2RAWA

Crystal structure of the borealin-survivin complex
Total Genus 44
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
44
sequence length
137
structure length
137
Chain Sequence
TLPPAWQPFLKDHRISTFKNWPFLEGCACTPERMAEAGFIHCPTENEPDLAQCFFCFKELEGWEPDDDPIEEHKKHSSGCAFLSVKKQFEELTLGEFLKLDRERAKNKIAKETNNKKKEFEETAKKVRRAIEQLAAM
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title The mitotic regulator Survivin binds as a monomer to its functional interactor Borealin.
pubmed doi rcsb
molecule tags Cell cycle
source organism Homo sapiens
molecule keywords Baculoviral IAP repeat-containing protein 5
total genus 44
structure length 137
sequence length 137
ec nomenclature
pdb deposition date 2007-09-17

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00653 BIR Inhibitor of Apoptosis domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.1170.10 Mainly Alpha Orthogonal Bundle Inhibitor Of Apoptosis Protein (2mihbC-IAP-1); Chain A Inhibitor Of Apoptosis Protein (2mihbC-IAP-1); Chain A 2rawA00
4EC4A 4LGUA 3UIKA 4WVSA 2RAXA 1OXQA 1I3OE 3D9UA 3G76A 1F3HA 4OXCA 5C84A 5C0KA 3M0DD 3UW5A 1G3FA 4WVTA 3UEHA 1TFTA 3UEDA 4A0NA 4MU7A 3F7IA 3OZ1A 1JD4A 2I3IA 1JD6A 3M1DA 4J47A 3UIGA 3MUPA 3F7HA 3UEGA 4HY5A 3GTAA 3T6PA 5C7CA 3EYLA 3UEIA 3UW4A 2JK7A 3CM7A 1QBHA 1TW6A 1XOXA 4KMPA 1XB0A 3CM2A 5C3HA 1OXNA 2QFAA 4KJUA 3UEFA 4HY4A 3UIIA 5C7BA 4MTIA 3F7GA 1C9QA 4EB9A 3UIJA 1G73C 5C83A 4J3YA 1TFQA 3CLXA 1SE0A 3D9TA 1OY7A 2OPZA 1XB1A 3GT9A 4J48A 4J44A 4J46A 3UIHA 2RAWA 2VM5A 3HL5A 1Q4QA 4MTZA 1SDZA 3M0AD 4A0IA 3SIPE 2UVLA 3UECA 4J45A 2POPB 2OPYA 4KJVA 1JD5A 1E31A 5C7AA 4A0JA 3SIQA 4KMNA 4LGEA 2I3HA 2POIA 2VSLA 1NW9A 5C7DA 5C0LA 1M4MA 3UEEA 4HY0A 5C3KA 2QRAA 4WVUA 1F9XA
chains in the Genus database with same CATH superfamily
4EC4A 4LGUA 3UIKA 4WVSA 2RAXA 1OXQA 1I3OE 3D9UA 3G76A 1F3HA 4OXCA 5C84A 5C0KA 3M0DD 3UW5A 1G3FA 4WVTA 3UEHA 1TFTA 3UEDA 4A0NA 4MU7A 3F7IA 3OZ1A 1JD4A 2I3IA 1JD6A 3M1DA 4J47A 3UIGA 3MUPA 3F7HA 3UEGA 4HY5A 3GTAA 3T6PA 5C7CA 3EYLA 3UEIA 3UW4A 2JK7A 3CM7A 1QBHA 1TW6A 1XOXA 4KMPA 1XB0A 3CM2A 5C3HA 1OXNA 2QFAA 4KJUA 3UEFA 4HY4A 3UIIA 5C7BA 4MTIA 3F7GA 1C9QA 4EB9A 3UIJA 1G73C 5C83A 4J3YA 1TFQA 3CLXA 1SE0A 3D9TA 1OY7A 2OPZA 1XB1A 3GT9A 4J48A 4J44A 4J46A 3UIHA 2RAWA 2VM5A 3HL5A 1Q4QA 4MTZA 1SDZA 3M0AD 4A0IA 3SIPE 2UVLA 3UECA 4J45A 2POPB 2OPYA 4KJVA 1JD5A 1E31A 5C7AA 4A0JA 3SIQA 4KMNA 4LGEA 2I3HA 2POIA 2VSLA 1NW9A 5C7DA 5C0LA 1M4MA 3UEEA 4HY0A 5C3KA 2QRAA 4WVUA 1F9XA
chains in the Genus database with same CATH topology
4EC4A 4LGUA 3UIKA 4WVSA 2RAXA 1OXQA 1I3OE 3D9UA 3G76A 1F3HA 4OXCA 5C84A 5C0KA 3M0DD 3UW5A 1G3FA 4WVTA 3UEHA 1TFTA 3UEDA 4A0NA 4MU7A 3F7IA 3OZ1A 1JD4A 2I3IA 1JD6A 3M1DA 4J47A 3UIGA 3MUPA 3F7HA 3UEGA 4HY5A 3GTAA 3T6PA 5C7CA 3EYLA 3UEIA 3UW4A 2JK7A 3CM7A 1QBHA 1TW6A 1XOXA 4KMPA 1XB0A 3CM2A 5C3HA 1OXNA 2QFAA 4KJUA 3UEFA 4HY4A 3UIIA 5C7BA 4MTIA 3F7GA 1C9QA 4EB9A 3UIJA 1G73C 5C83A 4J3YA 1TFQA 3CLXA 1SE0A 3D9TA 1OY7A 2OPZA 1XB1A 3GT9A 4J48A 4J44A 4J46A 3UIHA 2RAWA 2VM5A 3HL5A 1Q4QA 4MTZA 1SDZA 3M0AD 4A0IA 3SIPE 2UVLA 3UECA 4J45A 2POPB 2OPYA 4KJVA 1JD5A 1E31A 5C7AA 4A0JA 3SIQA 4KMNA 4LGEA 2I3HA 2POIA 2VSLA 1NW9A 5C7DA 5C0LA 1M4MA 3UEEA 4HY0A 5C3KA 2QRAA 4WVUA 1F9XA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4EC4 A;  4LGU A;  3UIK A;  4WVS A;  2RAX A;  1OXQ A;  1I3O E;  3D9U A;  3G76 A;  1F3H A;  4OXC A;  5C84 A;  5C0K A;  3M0D D;  3UW5 A;  1G3F A;  4WVT A;  3UEH A;  1TFT A;  3UED A;  4A0N A;  4MU7 A;  3F7I A;  3OZ1 A;  1JD4 A;  2I3I A;  1JD6 A;  3M1D A;  4J47 A;  3UIG A;  3MUP A;  3F7H A;  3UEG A;  4HY5 A;  3GTA A;  3T6P A;  5C7C A;  3EYL A;  3UEI A;  3UW4 A;  2JK7 A;  3CM7 A;  1QBH A;  1TW6 A;  1XOX A;  4KMP A;  1XB0 A;  3CM2 A;  5C3H A;  1OXN A;  2QFA A;  4KJU A;  3UEF A;  4HY4 A;  3UII A;  5C7B A;  4MTI A;  3F7G A;  1C9Q A;  4EB9 A;  3UIJ A;  1G73 C;  5C83 A;  4J3Y A;  1TFQ A;  3CLX A;  1SE0 A;  3D9T A;  1OY7 A;  2OPZ A;  1XB1 A;  3GT9 A;  4J48 A;  4J44 A;  4J46 A;  3UIH A;  2RAW A;  2VM5 A;  3HL5 A;  1Q4Q A;  4MTZ A;  1SDZ A;  3M0A D;  4A0I A;  3SIP E;  2UVL A;  3UEC A;  4J45 A;  2POP B;  2OPY A;  4KJV A;  1JD5 A;  1E31 A;  5C7A A;  4A0J A;  3SIQ A;  4KMN A;  4LGE A;  2I3H A;  2POI A;  2VSL A;  1NW9 A;  5C7D A;  5C0L A;  1M4M A;  3UEE A;  4HY0 A;  5C3K A;  2QRA A;  4WVU A;  1F9X A; 
#chains in the Genus database with same CATH topology
 4EC4 A;  4LGU A;  3UIK A;  4WVS A;  2RAX A;  1OXQ A;  1I3O E;  3D9U A;  3G76 A;  1F3H A;  4OXC A;  5C84 A;  5C0K A;  3M0D D;  3UW5 A;  1G3F A;  4WVT A;  3UEH A;  1TFT A;  3UED A;  4A0N A;  4MU7 A;  3F7I A;  3OZ1 A;  1JD4 A;  2I3I A;  1JD6 A;  3M1D A;  4J47 A;  3UIG A;  3MUP A;  3F7H A;  3UEG A;  4HY5 A;  3GTA A;  3T6P A;  5C7C A;  3EYL A;  3UEI A;  3UW4 A;  2JK7 A;  3CM7 A;  1QBH A;  1TW6 A;  1XOX A;  4KMP A;  1XB0 A;  3CM2 A;  5C3H A;  1OXN A;  2QFA A;  4KJU A;  3UEF A;  4HY4 A;  3UII A;  5C7B A;  4MTI A;  3F7G A;  1C9Q A;  4EB9 A;  3UIJ A;  1G73 C;  5C83 A;  4J3Y A;  1TFQ A;  3CLX A;  1SE0 A;  3D9T A;  1OY7 A;  2OPZ A;  1XB1 A;  3GT9 A;  4J48 A;  4J44 A;  4J46 A;  3UIH A;  2RAW A;  2VM5 A;  3HL5 A;  1Q4Q A;  4MTZ A;  1SDZ A;  3M0A D;  4A0I A;  3SIP E;  2UVL A;  3UEC A;  4J45 A;  2POP B;  2OPY A;  4KJV A;  1JD5 A;  1E31 A;  5C7A A;  4A0J A;  3SIQ A;  4KMN A;  4LGE A;  2I3H A;  2POI A;  2VSL A;  1NW9 A;  5C7D A;  5C0L A;  1M4M A;  3UEE A;  4HY0 A;  5C3K A;  2QRA A;  4WVU A;  1F9X A; 
#chains in the Genus database with same CATH homology
 4EC4 A;  4LGU A;  3UIK A;  4WVS A;  2RAX A;  1OXQ A;  1I3O E;  3D9U A;  3G76 A;  1F3H A;  4OXC A;  5C84 A;  5C0K A;  3M0D D;  3UW5 A;  1G3F A;  4WVT A;  3UEH A;  1TFT A;  3UED A;  4A0N A;  4MU7 A;  3F7I A;  3OZ1 A;  1JD4 A;  2I3I A;  1JD6 A;  3M1D A;  4J47 A;  3UIG A;  3MUP A;  3F7H A;  3UEG A;  4HY5 A;  3GTA A;  3T6P A;  5C7C A;  3EYL A;  3UEI A;  3UW4 A;  2JK7 A;  3CM7 A;  1QBH A;  1TW6 A;  1XOX A;  4KMP A;  1XB0 A;  3CM2 A;  5C3H A;  1OXN A;  2QFA A;  4KJU A;  3UEF A;  4HY4 A;  3UII A;  5C7B A;  4MTI A;  3F7G A;  1C9Q A;  4EB9 A;  3UIJ A;  1G73 C;  5C83 A;  4J3Y A;  1TFQ A;  3CLX A;  1SE0 A;  3D9T A;  1OY7 A;  2OPZ A;  1XB1 A;  3GT9 A;  4J48 A;  4J44 A;  4J46 A;  3UIH A;  2RAW A;  2VM5 A;  3HL5 A;  1Q4Q A;  4MTZ A;  1SDZ A;  3M0A D;  4A0I A;  3SIP E;  2UVL A;  3UEC A;  4J45 A;  2POP B;  2OPY A;  4KJV A;  1JD5 A;  1E31 A;  5C7A A;  4A0J A;  3SIQ A;  4KMN A;  4LGE A;  2I3H A;  2POI A;  2VSL A;  1NW9 A;  5C7D A;  5C0L A;  1M4M A;  3UEE A;  4HY0 A;  5C3K A;  2QRA A;  4WVU A;  1F9X A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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