2OPZA

Avpf bound to bir3-xiap
Total Genus 33
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
33
sequence length
109
structure length
109
Chain Sequence
NFPNSTNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTTE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Structure-activity based study of the Smac-binding pocket within the BIR3 domain of XIAP.
pubmed doi rcsb
molecule tags Apoptosis inhibitor
source organism Homo sapiens
molecule keywords Baculoviral IAP repeat-containing protein 4
total genus 33
structure length 109
sequence length 109
chains with identical sequence B, C, D
ec nomenclature ec 2.3.2.27: RING-type E3 ubiquitin transferase.
pdb deposition date 2007-01-30

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00653 BIR Inhibitor of Apoptosis domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.1170.10 Mainly Alpha Orthogonal Bundle Inhibitor Of Apoptosis Protein (2mihbC-IAP-1); Chain A Inhibitor Of Apoptosis Protein (2mihbC-IAP-1); Chain A 2opzA00
2POIA 3UIGA 4EC4A 4A0IA 3UEIA 1G3FA 5C7DA 4J47A 4KJVA 4EB9A 2VM5A 3UEHA 3CM7A 1XB0A 5C7CA 1Q4QA 1XB1A 2QFAA 3GT9A 1I3OE 4LGUA 4WVSA 4MTIA 3UEGA 3M0AD 4J3YA 1E31A 3CLXA 4HY5A 4A0JA 5C7AA 1XOXA 3F7GA 3EYLA 2JK7A 2OPYA 3SIPE 3HL5A 3M1DA 3G76A 1TFTA 5C0KA 4J48A 1F3HA 3T6PA 1OXQA 4KJUA 3CM2A 5C3HA 2RAWA 1JD6A 3UIJA 5C84A 1NW9A 4KMPA 4WVUA 3M0DD 1TFQA 5C3KA 4HY4A 1QBHA 4J46A 4J44A 1SE0A 4MTZA 1G73C 3D9TA 3GTAA 5C83A 3F7HA 4J45A 4HY0A 3UIIA 4A0NA 3D9UA 2OPZA 3MUPA 3UECA 5C7BA 1JD5A 5C0LA 1M4MA 3UIKA 3UIHA 4WVTA 1OXNA 3UW4A 3UEFA 2QRAA 4OXCA 1TW6A 4MU7A 1C9QA 2RAXA 2VSLA 1OY7A 2UVLA 4LGEA 3UW5A 3F7IA 2POPB 2I3HA 1F9XA 1SDZA 2I3IA 3UEEA 3SIQA 4KMNA 3OZ1A 1JD4A 3UEDA
chains in the Genus database with same CATH superfamily
2POIA 3UIGA 4EC4A 4A0IA 3UEIA 1G3FA 5C7DA 4J47A 4KJVA 4EB9A 2VM5A 3UEHA 3CM7A 1XB0A 5C7CA 1Q4QA 1XB1A 2QFAA 3GT9A 1I3OE 4LGUA 4WVSA 4MTIA 3UEGA 3M0AD 4J3YA 1E31A 3CLXA 4HY5A 4A0JA 5C7AA 1XOXA 3F7GA 3EYLA 2JK7A 2OPYA 3SIPE 3HL5A 3M1DA 3G76A 1TFTA 5C0KA 4J48A 1F3HA 3T6PA 1OXQA 4KJUA 3CM2A 5C3HA 2RAWA 1JD6A 3UIJA 5C84A 1NW9A 4KMPA 4WVUA 3M0DD 1TFQA 5C3KA 4HY4A 1QBHA 4J46A 4J44A 1SE0A 4MTZA 1G73C 3D9TA 3GTAA 5C83A 3F7HA 4J45A 4HY0A 3UIIA 4A0NA 3D9UA 2OPZA 3MUPA 3UECA 5C7BA 1JD5A 5C0LA 1M4MA 3UIKA 3UIHA 4WVTA 1OXNA 3UW4A 3UEFA 2QRAA 4OXCA 1TW6A 4MU7A 1C9QA 2RAXA 2VSLA 1OY7A 2UVLA 4LGEA 3UW5A 3F7IA 2POPB 2I3HA 1F9XA 1SDZA 2I3IA 3UEEA 3SIQA 4KMNA 3OZ1A 1JD4A 3UEDA
chains in the Genus database with same CATH topology
2POIA 3UIGA 4EC4A 4A0IA 3UEIA 1G3FA 5C7DA 4J47A 4KJVA 4EB9A 2VM5A 3UEHA 3CM7A 1XB0A 5C7CA 1Q4QA 1XB1A 2QFAA 3GT9A 1I3OE 4LGUA 4WVSA 4MTIA 3UEGA 3M0AD 4J3YA 1E31A 3CLXA 4HY5A 4A0JA 5C7AA 1XOXA 3F7GA 3EYLA 2JK7A 2OPYA 3SIPE 3HL5A 3M1DA 3G76A 1TFTA 5C0KA 4J48A 1F3HA 3T6PA 1OXQA 4KJUA 3CM2A 5C3HA 2RAWA 1JD6A 3UIJA 5C84A 1NW9A 4KMPA 4WVUA 3M0DD 1TFQA 5C3KA 4HY4A 1QBHA 4J46A 4J44A 1SE0A 4MTZA 1G73C 3D9TA 3GTAA 5C83A 3F7HA 4J45A 4HY0A 3UIIA 4A0NA 3D9UA 2OPZA 3MUPA 3UECA 5C7BA 1JD5A 5C0LA 1M4MA 3UIKA 3UIHA 4WVTA 1OXNA 3UW4A 3UEFA 2QRAA 4OXCA 1TW6A 4MU7A 1C9QA 2RAXA 2VSLA 1OY7A 2UVLA 4LGEA 3UW5A 3F7IA 2POPB 2I3HA 1F9XA 1SDZA 2I3IA 3UEEA 3SIQA 4KMNA 3OZ1A 1JD4A 3UEDA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2POI A;  3UIG A;  4EC4 A;  4A0I A;  3UEI A;  1G3F A;  5C7D A;  4J47 A;  4KJV A;  4EB9 A;  2VM5 A;  3UEH A;  3CM7 A;  1XB0 A;  5C7C A;  1Q4Q A;  1XB1 A;  2QFA A;  3GT9 A;  1I3O E;  4LGU A;  4WVS A;  4MTI A;  3UEG A;  3M0A D;  4J3Y A;  1E31 A;  3CLX A;  4HY5 A;  4A0J A;  5C7A A;  1XOX A;  3F7G A;  3EYL A;  2JK7 A;  2OPY A;  3SIP E;  3HL5 A;  3M1D A;  3G76 A;  1TFT A;  5C0K A;  4J48 A;  1F3H A;  3T6P A;  1OXQ A;  4KJU A;  3CM2 A;  5C3H A;  2RAW A;  1JD6 A;  3UIJ A;  5C84 A;  1NW9 A;  4KMP A;  4WVU A;  3M0D D;  1TFQ A;  5C3K A;  4HY4 A;  1QBH A;  4J46 A;  4J44 A;  1SE0 A;  4MTZ A;  1G73 C;  3D9T A;  3GTA A;  5C83 A;  3F7H A;  4J45 A;  4HY0 A;  3UII A;  4A0N A;  3D9U A;  2OPZ A;  3MUP A;  3UEC A;  5C7B A;  1JD5 A;  5C0L A;  1M4M A;  3UIK A;  3UIH A;  4WVT A;  1OXN A;  3UW4 A;  3UEF A;  2QRA A;  4OXC A;  1TW6 A;  4MU7 A;  1C9Q A;  2RAX A;  2VSL A;  1OY7 A;  2UVL A;  4LGE A;  3UW5 A;  3F7I A;  2POP B;  2I3H A;  1F9X A;  1SDZ A;  2I3I A;  3UEE A;  3SIQ A;  4KMN A;  3OZ1 A;  1JD4 A;  3UED A; 
#chains in the Genus database with same CATH topology
 2POI A;  3UIG A;  4EC4 A;  4A0I A;  3UEI A;  1G3F A;  5C7D A;  4J47 A;  4KJV A;  4EB9 A;  2VM5 A;  3UEH A;  3CM7 A;  1XB0 A;  5C7C A;  1Q4Q A;  1XB1 A;  2QFA A;  3GT9 A;  1I3O E;  4LGU A;  4WVS A;  4MTI A;  3UEG A;  3M0A D;  4J3Y A;  1E31 A;  3CLX A;  4HY5 A;  4A0J A;  5C7A A;  1XOX A;  3F7G A;  3EYL A;  2JK7 A;  2OPY A;  3SIP E;  3HL5 A;  3M1D A;  3G76 A;  1TFT A;  5C0K A;  4J48 A;  1F3H A;  3T6P A;  1OXQ A;  4KJU A;  3CM2 A;  5C3H A;  2RAW A;  1JD6 A;  3UIJ A;  5C84 A;  1NW9 A;  4KMP A;  4WVU A;  3M0D D;  1TFQ A;  5C3K A;  4HY4 A;  1QBH A;  4J46 A;  4J44 A;  1SE0 A;  4MTZ A;  1G73 C;  3D9T A;  3GTA A;  5C83 A;  3F7H A;  4J45 A;  4HY0 A;  3UII A;  4A0N A;  3D9U A;  2OPZ A;  3MUP A;  3UEC A;  5C7B A;  1JD5 A;  5C0L A;  1M4M A;  3UIK A;  3UIH A;  4WVT A;  1OXN A;  3UW4 A;  3UEF A;  2QRA A;  4OXC A;  1TW6 A;  4MU7 A;  1C9Q A;  2RAX A;  2VSL A;  1OY7 A;  2UVL A;  4LGE A;  3UW5 A;  3F7I A;  2POP B;  2I3H A;  1F9X A;  1SDZ A;  2I3I A;  3UEE A;  3SIQ A;  4KMN A;  3OZ1 A;  1JD4 A;  3UED A; 
#chains in the Genus database with same CATH homology
 2POI A;  3UIG A;  4EC4 A;  4A0I A;  3UEI A;  1G3F A;  5C7D A;  4J47 A;  4KJV A;  4EB9 A;  2VM5 A;  3UEH A;  3CM7 A;  1XB0 A;  5C7C A;  1Q4Q A;  1XB1 A;  2QFA A;  3GT9 A;  1I3O E;  4LGU A;  4WVS A;  4MTI A;  3UEG A;  3M0A D;  4J3Y A;  1E31 A;  3CLX A;  4HY5 A;  4A0J A;  5C7A A;  1XOX A;  3F7G A;  3EYL A;  2JK7 A;  2OPY A;  3SIP E;  3HL5 A;  3M1D A;  3G76 A;  1TFT A;  5C0K A;  4J48 A;  1F3H A;  3T6P A;  1OXQ A;  4KJU A;  3CM2 A;  5C3H A;  2RAW A;  1JD6 A;  3UIJ A;  5C84 A;  1NW9 A;  4KMP A;  4WVU A;  3M0D D;  1TFQ A;  5C3K A;  4HY4 A;  1QBH A;  4J46 A;  4J44 A;  1SE0 A;  4MTZ A;  1G73 C;  3D9T A;  3GTA A;  5C83 A;  3F7H A;  4J45 A;  4HY0 A;  3UII A;  4A0N A;  3D9U A;  2OPZ A;  3MUP A;  3UEC A;  5C7B A;  1JD5 A;  5C0L A;  1M4M A;  3UIK A;  3UIH A;  4WVT A;  1OXN A;  3UW4 A;  3UEF A;  2QRA A;  4OXC A;  1TW6 A;  4MU7 A;  1C9Q A;  2RAX A;  2VSL A;  1OY7 A;  2UVL A;  4LGE A;  3UW5 A;  3F7I A;  2POP B;  2I3H A;  1F9X A;  1SDZ A;  2I3I A;  3UEE A;  3SIQ A;  4KMN A;  3OZ1 A;  1JD4 A;  3UED A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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