2POIA

Crystal structure of xiap bir1 domain (i222 form)
Total Genus 21
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
21
sequence length
78
structure length
78
Chain Sequence
EFVEEFNRLKTFANFPSGSPVSASTLARAGFLYTGEGDTVRCFSCHAAVDRWQYGDSAVGRHRKVSPNCRFINGFYLE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title XIAP Induces NF-kappaB Activation via the BIR1/TAB1 Interaction and BIR1 Dimerization.
pubmed doi rcsb
molecule tags Signaling protein/apoptosis
source organism Homo sapiens
molecule keywords Baculoviral IAP repeat-containing protein 4
total genus 21
structure length 78
sequence length 78
ec nomenclature ec 2.3.2.27: RING-type E3 ubiquitin transferase.
pdb deposition date 2007-04-26

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00653 BIR Inhibitor of Apoptosis domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.1170.10 Mainly Alpha Orthogonal Bundle Inhibitor Of Apoptosis Protein (2mihbC-IAP-1); Chain A Inhibitor Of Apoptosis Protein (2mihbC-IAP-1); Chain A 2poiA00
3CLXA 2OPZA 4WVUA 3CM7A 3M0DD 3UECA 1XB1A 3F7HA 1G73C 4MTZA 1OXNA 4HY0A 4LGUA 4WVTA 2RAWA 3UEHA 1E31A 3UW5A 3UIJA 4KJVA 3M1DA 5C7BA 4A0JA 4J46A 4J44A 1TFQA 1SDZA 3SIPE 4HY5A 5C3KA 1JD5A 3UIIA 2QFAA 4WVSA 1I3OE 2RAXA 3OZ1A 4J48A 1XOXA 5C0KA 4HY4A 5C7DA 5C0LA 2I3IA 2POPB 2UVLA 3GTAA 3UEFA 1F9XA 4LGEA 2VM5A 2VSLA 3GT9A 4A0NA 2POIA 4MU7A 1JD6A 3T6PA 3UW4A 3MUPA 1G3FA 1M4MA 1Q4QA 3CM2A 3F7IA 1OY7A 1XB0A 4J3YA 3EYLA 3HL5A 3UEEA 3F7GA 2I3HA 5C83A 3SIQA 4J45A 3M0AD 1TFTA 2OPYA 2QRAA 1SE0A 3UIHA 1JD4A 4KJUA 5C7AA 5C84A 4MTIA 3D9TA 4A0IA 1QBHA 1TW6A 4EB9A 3UIGA 3G76A 1OXQA 3UEDA 4EC4A 5C7CA 3UEIA 3D9UA 4OXCA 4KMNA 1NW9A 4KMPA 5C3HA 3UIKA 4J47A 3UEGA 1C9QA 1F3HA 2JK7A
chains in the Genus database with same CATH superfamily
3CLXA 2OPZA 4WVUA 3CM7A 3M0DD 3UECA 1XB1A 3F7HA 1G73C 4MTZA 1OXNA 4HY0A 4LGUA 4WVTA 2RAWA 3UEHA 1E31A 3UW5A 3UIJA 4KJVA 3M1DA 5C7BA 4A0JA 4J46A 4J44A 1TFQA 1SDZA 3SIPE 4HY5A 5C3KA 1JD5A 3UIIA 2QFAA 4WVSA 1I3OE 2RAXA 3OZ1A 4J48A 1XOXA 5C0KA 4HY4A 5C7DA 5C0LA 2I3IA 2POPB 2UVLA 3GTAA 3UEFA 1F9XA 4LGEA 2VM5A 2VSLA 3GT9A 4A0NA 2POIA 4MU7A 1JD6A 3T6PA 3UW4A 3MUPA 1G3FA 1M4MA 1Q4QA 3CM2A 3F7IA 1OY7A 1XB0A 4J3YA 3EYLA 3HL5A 3UEEA 3F7GA 2I3HA 5C83A 3SIQA 4J45A 3M0AD 1TFTA 2OPYA 2QRAA 1SE0A 3UIHA 1JD4A 4KJUA 5C7AA 5C84A 4MTIA 3D9TA 4A0IA 1QBHA 1TW6A 4EB9A 3UIGA 3G76A 1OXQA 3UEDA 4EC4A 5C7CA 3UEIA 3D9UA 4OXCA 4KMNA 1NW9A 4KMPA 5C3HA 3UIKA 4J47A 3UEGA 1C9QA 1F3HA 2JK7A
chains in the Genus database with same CATH topology
3CLXA 2OPZA 4WVUA 3CM7A 3M0DD 3UECA 1XB1A 3F7HA 1G73C 4MTZA 1OXNA 4HY0A 4LGUA 4WVTA 2RAWA 3UEHA 1E31A 3UW5A 3UIJA 4KJVA 3M1DA 5C7BA 4A0JA 4J46A 4J44A 1TFQA 1SDZA 3SIPE 4HY5A 5C3KA 1JD5A 3UIIA 2QFAA 4WVSA 1I3OE 2RAXA 3OZ1A 4J48A 1XOXA 5C0KA 4HY4A 5C7DA 5C0LA 2I3IA 2POPB 2UVLA 3GTAA 3UEFA 1F9XA 4LGEA 2VM5A 2VSLA 3GT9A 4A0NA 2POIA 4MU7A 1JD6A 3T6PA 3UW4A 3MUPA 1G3FA 1M4MA 1Q4QA 3CM2A 3F7IA 1OY7A 1XB0A 4J3YA 3EYLA 3HL5A 3UEEA 3F7GA 2I3HA 5C83A 3SIQA 4J45A 3M0AD 1TFTA 2OPYA 2QRAA 1SE0A 3UIHA 1JD4A 4KJUA 5C7AA 5C84A 4MTIA 3D9TA 4A0IA 1QBHA 1TW6A 4EB9A 3UIGA 3G76A 1OXQA 3UEDA 4EC4A 5C7CA 3UEIA 3D9UA 4OXCA 4KMNA 1NW9A 4KMPA 5C3HA 3UIKA 4J47A 3UEGA 1C9QA 1F3HA 2JK7A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3CLX A;  2OPZ A;  4WVU A;  3CM7 A;  3M0D D;  3UEC A;  1XB1 A;  3F7H A;  1G73 C;  4MTZ A;  1OXN A;  4HY0 A;  4LGU A;  4WVT A;  2RAW A;  3UEH A;  1E31 A;  3UW5 A;  3UIJ A;  4KJV A;  3M1D A;  5C7B A;  4A0J A;  4J46 A;  4J44 A;  1TFQ A;  1SDZ A;  3SIP E;  4HY5 A;  5C3K A;  1JD5 A;  3UII A;  2QFA A;  4WVS A;  1I3O E;  2RAX A;  3OZ1 A;  4J48 A;  1XOX A;  5C0K A;  4HY4 A;  5C7D A;  5C0L A;  2I3I A;  2POP B;  2UVL A;  3GTA A;  3UEF A;  1F9X A;  4LGE A;  2VM5 A;  2VSL A;  3GT9 A;  4A0N A;  2POI A;  4MU7 A;  1JD6 A;  3T6P A;  3UW4 A;  3MUP A;  1G3F A;  1M4M A;  1Q4Q A;  3CM2 A;  3F7I A;  1OY7 A;  1XB0 A;  4J3Y A;  3EYL A;  3HL5 A;  3UEE A;  3F7G A;  2I3H A;  5C83 A;  3SIQ A;  4J45 A;  3M0A D;  1TFT A;  2OPY A;  2QRA A;  1SE0 A;  3UIH A;  1JD4 A;  4KJU A;  5C7A A;  5C84 A;  4MTI A;  3D9T A;  4A0I A;  1QBH A;  1TW6 A;  4EB9 A;  3UIG A;  3G76 A;  1OXQ A;  3UED A;  4EC4 A;  5C7C A;  3UEI A;  3D9U A;  4OXC A;  4KMN A;  1NW9 A;  4KMP A;  5C3H A;  3UIK A;  4J47 A;  3UEG A;  1C9Q A;  1F3H A;  2JK7 A; 
#chains in the Genus database with same CATH topology
 3CLX A;  2OPZ A;  4WVU A;  3CM7 A;  3M0D D;  3UEC A;  1XB1 A;  3F7H A;  1G73 C;  4MTZ A;  1OXN A;  4HY0 A;  4LGU A;  4WVT A;  2RAW A;  3UEH A;  1E31 A;  3UW5 A;  3UIJ A;  4KJV A;  3M1D A;  5C7B A;  4A0J A;  4J46 A;  4J44 A;  1TFQ A;  1SDZ A;  3SIP E;  4HY5 A;  5C3K A;  1JD5 A;  3UII A;  2QFA A;  4WVS A;  1I3O E;  2RAX A;  3OZ1 A;  4J48 A;  1XOX A;  5C0K A;  4HY4 A;  5C7D A;  5C0L A;  2I3I A;  2POP B;  2UVL A;  3GTA A;  3UEF A;  1F9X A;  4LGE A;  2VM5 A;  2VSL A;  3GT9 A;  4A0N A;  2POI A;  4MU7 A;  1JD6 A;  3T6P A;  3UW4 A;  3MUP A;  1G3F A;  1M4M A;  1Q4Q A;  3CM2 A;  3F7I A;  1OY7 A;  1XB0 A;  4J3Y A;  3EYL A;  3HL5 A;  3UEE A;  3F7G A;  2I3H A;  5C83 A;  3SIQ A;  4J45 A;  3M0A D;  1TFT A;  2OPY A;  2QRA A;  1SE0 A;  3UIH A;  1JD4 A;  4KJU A;  5C7A A;  5C84 A;  4MTI A;  3D9T A;  4A0I A;  1QBH A;  1TW6 A;  4EB9 A;  3UIG A;  3G76 A;  1OXQ A;  3UED A;  4EC4 A;  5C7C A;  3UEI A;  3D9U A;  4OXC A;  4KMN A;  1NW9 A;  4KMP A;  5C3H A;  3UIK A;  4J47 A;  3UEG A;  1C9Q A;  1F3H A;  2JK7 A; 
#chains in the Genus database with same CATH homology
 3CLX A;  2OPZ A;  4WVU A;  3CM7 A;  3M0D D;  3UEC A;  1XB1 A;  3F7H A;  1G73 C;  4MTZ A;  1OXN A;  4HY0 A;  4LGU A;  4WVT A;  2RAW A;  3UEH A;  1E31 A;  3UW5 A;  3UIJ A;  4KJV A;  3M1D A;  5C7B A;  4A0J A;  4J46 A;  4J44 A;  1TFQ A;  1SDZ A;  3SIP E;  4HY5 A;  5C3K A;  1JD5 A;  3UII A;  2QFA A;  4WVS A;  1I3O E;  2RAX A;  3OZ1 A;  4J48 A;  1XOX A;  5C0K A;  4HY4 A;  5C7D A;  5C0L A;  2I3I A;  2POP B;  2UVL A;  3GTA A;  3UEF A;  1F9X A;  4LGE A;  2VM5 A;  2VSL A;  3GT9 A;  4A0N A;  2POI A;  4MU7 A;  1JD6 A;  3T6P A;  3UW4 A;  3MUP A;  1G3F A;  1M4M A;  1Q4Q A;  3CM2 A;  3F7I A;  1OY7 A;  1XB0 A;  4J3Y A;  3EYL A;  3HL5 A;  3UEE A;  3F7G A;  2I3H A;  5C83 A;  3SIQ A;  4J45 A;  3M0A D;  1TFT A;  2OPY A;  2QRA A;  1SE0 A;  3UIH A;  1JD4 A;  4KJU A;  5C7A A;  5C84 A;  4MTI A;  3D9T A;  4A0I A;  1QBH A;  1TW6 A;  4EB9 A;  3UIG A;  3G76 A;  1OXQ A;  3UED A;  4EC4 A;  5C7C A;  3UEI A;  3D9U A;  4OXC A;  4KMN A;  1NW9 A;  4KMP A;  5C3H A;  3UIK A;  4J47 A;  3UEG A;  1C9Q A;  1F3H A;  2JK7 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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