2QRAA

Crystal structure of xiap bir1 domain (p21 form)
Total Genus 23
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
23
sequence length
80
structure length
80
Chain Sequence
EEEFVEEFNRLKTFANFPSGSPVSASTLARAGFLYTGEGDTVRCFSCHAAVDRWQYGDSAVGRHRKVSPNCRFINGFYLE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal structure of the BIR1 domain of XIAP in two crystal forms
pubmed doi rcsb
molecule tags Apoptosis, signaling protein
source organism Homo sapiens
molecule keywords Baculoviral IAP repeat-containing protein 4
total genus 23
structure length 80
sequence length 80
chains with identical sequence B, C, D
ec nomenclature ec 2.3.2.27: RING-type E3 ubiquitin transferase.
pdb deposition date 2007-07-27

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00653 BIR Inhibitor of Apoptosis domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.1170.10 Mainly Alpha Orthogonal Bundle Inhibitor Of Apoptosis Protein (2mihbC-IAP-1); Chain A Inhibitor Of Apoptosis Protein (2mihbC-IAP-1); Chain A 2qraA00
5C7CA 3UIJA 1F9XA 3F7IA 1F3HA 4J46A 3UIIA 4KMNA 4J47A 4LGEA 2I3HA 4A0IA 3D9UA 5C3KA 1C9QA 5C83A 3CM2A 4LGUA 2POPB 2VSLA 1SE0A 3CLXA 1M4MA 1TFTA 1NW9A 2VM5A 4MTZA 1JD6A 3G76A 4WVTA 3UIKA 4OXCA 1Q4QA 2RAWA 3MUPA 5C0KA 3UW4A 5C7DA 3EYLA 1XB0A 4J44A 4HY5A 3M0DD 3OZ1A 4MTIA 5C3HA 3SIPE 1G3FA 4KJVA 3UEIA 5C7AA 2RAXA 3M1DA 2OPYA 3UEGA 4J48A 2I3IA 3UEEA 5C7BA 1OXQA 3UIGA 4WVSA 1I3OE 1OXNA 1JD5A 1E31A 3F7HA 3GT9A 3F7GA 3SIQA 3UEFA 3UECA 1G73C 4HY0A 4J3YA 3UW5A 4WVUA 1SDZA 5C84A 3UEHA 1TFQA 1XOXA 1JD4A 3M0AD 4J45A 3UEDA 3GTAA 4KMPA 1QBHA 4KJUA 1XB1A 2QRAA 1OY7A 4EB9A 4A0JA 4EC4A 4A0NA 4MU7A 3HL5A 5C0LA 3CM7A 3T6PA 2UVLA 2OPZA 2POIA 1TW6A 3D9TA 4HY4A 3UIHA 2JK7A 2QFAA
chains in the Genus database with same CATH superfamily
5C7CA 3UIJA 1F9XA 3F7IA 1F3HA 4J46A 3UIIA 4KMNA 4J47A 4LGEA 2I3HA 4A0IA 3D9UA 5C3KA 1C9QA 5C83A 3CM2A 4LGUA 2POPB 2VSLA 1SE0A 3CLXA 1M4MA 1TFTA 1NW9A 2VM5A 4MTZA 1JD6A 3G76A 4WVTA 3UIKA 4OXCA 1Q4QA 2RAWA 3MUPA 5C0KA 3UW4A 5C7DA 3EYLA 1XB0A 4J44A 4HY5A 3M0DD 3OZ1A 4MTIA 5C3HA 3SIPE 1G3FA 4KJVA 3UEIA 5C7AA 2RAXA 3M1DA 2OPYA 3UEGA 4J48A 2I3IA 3UEEA 5C7BA 1OXQA 3UIGA 4WVSA 1I3OE 1OXNA 1JD5A 1E31A 3F7HA 3GT9A 3F7GA 3SIQA 3UEFA 3UECA 1G73C 4HY0A 4J3YA 3UW5A 4WVUA 1SDZA 5C84A 3UEHA 1TFQA 1XOXA 1JD4A 3M0AD 4J45A 3UEDA 3GTAA 4KMPA 1QBHA 4KJUA 1XB1A 2QRAA 1OY7A 4EB9A 4A0JA 4EC4A 4A0NA 4MU7A 3HL5A 5C0LA 3CM7A 3T6PA 2UVLA 2OPZA 2POIA 1TW6A 3D9TA 4HY4A 3UIHA 2JK7A 2QFAA
chains in the Genus database with same CATH topology
5C7CA 3UIJA 1F9XA 3F7IA 1F3HA 4J46A 3UIIA 4KMNA 4J47A 4LGEA 2I3HA 4A0IA 3D9UA 5C3KA 1C9QA 5C83A 3CM2A 4LGUA 2POPB 2VSLA 1SE0A 3CLXA 1M4MA 1TFTA 1NW9A 2VM5A 4MTZA 1JD6A 3G76A 4WVTA 3UIKA 4OXCA 1Q4QA 2RAWA 3MUPA 5C0KA 3UW4A 5C7DA 3EYLA 1XB0A 4J44A 4HY5A 3M0DD 3OZ1A 4MTIA 5C3HA 3SIPE 1G3FA 4KJVA 3UEIA 5C7AA 2RAXA 3M1DA 2OPYA 3UEGA 4J48A 2I3IA 3UEEA 5C7BA 1OXQA 3UIGA 4WVSA 1I3OE 1OXNA 1JD5A 1E31A 3F7HA 3GT9A 3F7GA 3SIQA 3UEFA 3UECA 1G73C 4HY0A 4J3YA 3UW5A 4WVUA 1SDZA 5C84A 3UEHA 1TFQA 1XOXA 1JD4A 3M0AD 4J45A 3UEDA 3GTAA 4KMPA 1QBHA 4KJUA 1XB1A 2QRAA 1OY7A 4EB9A 4A0JA 4EC4A 4A0NA 4MU7A 3HL5A 5C0LA 3CM7A 3T6PA 2UVLA 2OPZA 2POIA 1TW6A 3D9TA 4HY4A 3UIHA 2JK7A 2QFAA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5C7C A;  3UIJ A;  1F9X A;  3F7I A;  1F3H A;  4J46 A;  3UII A;  4KMN A;  4J47 A;  4LGE A;  2I3H A;  4A0I A;  3D9U A;  5C3K A;  1C9Q A;  5C83 A;  3CM2 A;  4LGU A;  2POP B;  2VSL A;  1SE0 A;  3CLX A;  1M4M A;  1TFT A;  1NW9 A;  2VM5 A;  4MTZ A;  1JD6 A;  3G76 A;  4WVT A;  3UIK A;  4OXC A;  1Q4Q A;  2RAW A;  3MUP A;  5C0K A;  3UW4 A;  5C7D A;  3EYL A;  1XB0 A;  4J44 A;  4HY5 A;  3M0D D;  3OZ1 A;  4MTI A;  5C3H A;  3SIP E;  1G3F A;  4KJV A;  3UEI A;  5C7A A;  2RAX A;  3M1D A;  2OPY A;  3UEG A;  4J48 A;  2I3I A;  3UEE A;  5C7B A;  1OXQ A;  3UIG A;  4WVS A;  1I3O E;  1OXN A;  1JD5 A;  1E31 A;  3F7H A;  3GT9 A;  3F7G A;  3SIQ A;  3UEF A;  3UEC A;  1G73 C;  4HY0 A;  4J3Y A;  3UW5 A;  4WVU A;  1SDZ A;  5C84 A;  3UEH A;  1TFQ A;  1XOX A;  1JD4 A;  3M0A D;  4J45 A;  3UED A;  3GTA A;  4KMP A;  1QBH A;  4KJU A;  1XB1 A;  2QRA A;  1OY7 A;  4EB9 A;  4A0J A;  4EC4 A;  4A0N A;  4MU7 A;  3HL5 A;  5C0L A;  3CM7 A;  3T6P A;  2UVL A;  2OPZ A;  2POI A;  1TW6 A;  3D9T A;  4HY4 A;  3UIH A;  2JK7 A;  2QFA A; 
#chains in the Genus database with same CATH topology
 5C7C A;  3UIJ A;  1F9X A;  3F7I A;  1F3H A;  4J46 A;  3UII A;  4KMN A;  4J47 A;  4LGE A;  2I3H A;  4A0I A;  3D9U A;  5C3K A;  1C9Q A;  5C83 A;  3CM2 A;  4LGU A;  2POP B;  2VSL A;  1SE0 A;  3CLX A;  1M4M A;  1TFT A;  1NW9 A;  2VM5 A;  4MTZ A;  1JD6 A;  3G76 A;  4WVT A;  3UIK A;  4OXC A;  1Q4Q A;  2RAW A;  3MUP A;  5C0K A;  3UW4 A;  5C7D A;  3EYL A;  1XB0 A;  4J44 A;  4HY5 A;  3M0D D;  3OZ1 A;  4MTI A;  5C3H A;  3SIP E;  1G3F A;  4KJV A;  3UEI A;  5C7A A;  2RAX A;  3M1D A;  2OPY A;  3UEG A;  4J48 A;  2I3I A;  3UEE A;  5C7B A;  1OXQ A;  3UIG A;  4WVS A;  1I3O E;  1OXN A;  1JD5 A;  1E31 A;  3F7H A;  3GT9 A;  3F7G A;  3SIQ A;  3UEF A;  3UEC A;  1G73 C;  4HY0 A;  4J3Y A;  3UW5 A;  4WVU A;  1SDZ A;  5C84 A;  3UEH A;  1TFQ A;  1XOX A;  1JD4 A;  3M0A D;  4J45 A;  3UED A;  3GTA A;  4KMP A;  1QBH A;  4KJU A;  1XB1 A;  2QRA A;  1OY7 A;  4EB9 A;  4A0J A;  4EC4 A;  4A0N A;  4MU7 A;  3HL5 A;  5C0L A;  3CM7 A;  3T6P A;  2UVL A;  2OPZ A;  2POI A;  1TW6 A;  3D9T A;  4HY4 A;  3UIH A;  2JK7 A;  2QFA A; 
#chains in the Genus database with same CATH homology
 5C7C A;  3UIJ A;  1F9X A;  3F7I A;  1F3H A;  4J46 A;  3UII A;  4KMN A;  4J47 A;  4LGE A;  2I3H A;  4A0I A;  3D9U A;  5C3K A;  1C9Q A;  5C83 A;  3CM2 A;  4LGU A;  2POP B;  2VSL A;  1SE0 A;  3CLX A;  1M4M A;  1TFT A;  1NW9 A;  2VM5 A;  4MTZ A;  1JD6 A;  3G76 A;  4WVT A;  3UIK A;  4OXC A;  1Q4Q A;  2RAW A;  3MUP A;  5C0K A;  3UW4 A;  5C7D A;  3EYL A;  1XB0 A;  4J44 A;  4HY5 A;  3M0D D;  3OZ1 A;  4MTI A;  5C3H A;  3SIP E;  1G3F A;  4KJV A;  3UEI A;  5C7A A;  2RAX A;  3M1D A;  2OPY A;  3UEG A;  4J48 A;  2I3I A;  3UEE A;  5C7B A;  1OXQ A;  3UIG A;  4WVS A;  1I3O E;  1OXN A;  1JD5 A;  1E31 A;  3F7H A;  3GT9 A;  3F7G A;  3SIQ A;  3UEF A;  3UEC A;  1G73 C;  4HY0 A;  4J3Y A;  3UW5 A;  4WVU A;  1SDZ A;  5C84 A;  3UEH A;  1TFQ A;  1XOX A;  1JD4 A;  3M0A D;  4J45 A;  3UED A;  3GTA A;  4KMP A;  1QBH A;  4KJU A;  1XB1 A;  2QRA A;  1OY7 A;  4EB9 A;  4A0J A;  4EC4 A;  4A0N A;  4MU7 A;  3HL5 A;  5C0L A;  3CM7 A;  3T6P A;  2UVL A;  2OPZ A;  2POI A;  1TW6 A;  3D9T A;  4HY4 A;  3UIH A;  2JK7 A;  2QFA A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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