2VSLA

Crystal structure of xiap bir3 with a bivalent smac mimetic
Total Genus 27
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
27
sequence length
96
structure length
96
Chain Sequence
FPNSTNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLT
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Interaction of a Cyclic, Bivalent Smac Mimetic with the X-Linked Inhibitor of Apoptosis Protein.
pubmed doi rcsb
molecule tags Ligase
source organism Homo sapiens
molecule keywords BACULOVIRAL IAP REPEAT-CONTAINING PROTEIN 4
total genus 27
structure length 96
sequence length 96
ec nomenclature ec 2.3.2.27: RING-type E3 ubiquitin transferase.
pdb deposition date 2008-04-24

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00653 BIR Inhibitor of Apoptosis domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.1170.10 Mainly Alpha Orthogonal Bundle Inhibitor Of Apoptosis Protein (2mihbC-IAP-1); Chain A Inhibitor Of Apoptosis Protein (2mihbC-IAP-1); Chain A 2vslA00
3M0AD 2RAXA 2QFAA 4WVUA 3UIKA 4HY4A 4KJVA 4EB9A 5C7DA 4MTIA 3UEEA 3UECA 3SIQA 3OZ1A 1C9QA 1G3FA 2POIA 3UIHA 3F7HA 5C7AA 1OY7A 1XB1A 2JK7A 1SE0A 4KMPA 1SDZA 2POPB 3CM2A 3D9UA 4WVSA 3M0DD 3G76A 3GTAA 2I3IA 1OXQA 2QRAA 2OPYA 4J44A 3F7IA 4J3YA 4A0JA 3UIGA 4KJUA 4HY0A 2RAWA 1JD4A 1QBHA 4MTZA 3T6PA 2VSLA 4LGUA 1OXNA 1TW6A 1G73C 3UEHA 4KMNA 5C3KA 1NW9A 1TFTA 1M4MA 3UEDA 1F9XA 5C7CA 4EC4A 4WVTA 3GT9A 1F3HA 5C3HA 4J47A 3UIIA 3CLXA 3SIPE 1I3OE 1Q4QA 4A0NA 3CM7A 2UVLA 1JD5A 1TFQA 3HL5A 3UEGA 4J45A 1XOXA 5C84A 2I3HA 4HY5A 3UIJA 3MUPA 1E31A 1XB0A 4OXCA 2OPZA 4A0IA 4J48A 5C7BA 3UEFA 3F7GA 3UW5A 1JD6A 5C0LA 4LGEA 3M1DA 3UW4A 2VM5A 5C0KA 3D9TA 5C83A 4MU7A 4J46A 3EYLA 3UEIA
chains in the Genus database with same CATH superfamily
3M0AD 2RAXA 2QFAA 4WVUA 3UIKA 4HY4A 4KJVA 4EB9A 5C7DA 4MTIA 3UEEA 3UECA 3SIQA 3OZ1A 1C9QA 1G3FA 2POIA 3UIHA 3F7HA 5C7AA 1OY7A 1XB1A 2JK7A 1SE0A 4KMPA 1SDZA 2POPB 3CM2A 3D9UA 4WVSA 3M0DD 3G76A 3GTAA 2I3IA 1OXQA 2QRAA 2OPYA 4J44A 3F7IA 4J3YA 4A0JA 3UIGA 4KJUA 4HY0A 2RAWA 1JD4A 1QBHA 4MTZA 3T6PA 2VSLA 4LGUA 1OXNA 1TW6A 1G73C 3UEHA 4KMNA 5C3KA 1NW9A 1TFTA 1M4MA 3UEDA 1F9XA 5C7CA 4EC4A 4WVTA 3GT9A 1F3HA 5C3HA 4J47A 3UIIA 3CLXA 3SIPE 1I3OE 1Q4QA 4A0NA 3CM7A 2UVLA 1JD5A 1TFQA 3HL5A 3UEGA 4J45A 1XOXA 5C84A 2I3HA 4HY5A 3UIJA 3MUPA 1E31A 1XB0A 4OXCA 2OPZA 4A0IA 4J48A 5C7BA 3UEFA 3F7GA 3UW5A 1JD6A 5C0LA 4LGEA 3M1DA 3UW4A 2VM5A 5C0KA 3D9TA 5C83A 4MU7A 4J46A 3EYLA 3UEIA
chains in the Genus database with same CATH topology
3M0AD 2RAXA 2QFAA 4WVUA 3UIKA 4HY4A 4KJVA 4EB9A 5C7DA 4MTIA 3UEEA 3UECA 3SIQA 3OZ1A 1C9QA 1G3FA 2POIA 3UIHA 3F7HA 5C7AA 1OY7A 1XB1A 2JK7A 1SE0A 4KMPA 1SDZA 2POPB 3CM2A 3D9UA 4WVSA 3M0DD 3G76A 3GTAA 2I3IA 1OXQA 2QRAA 2OPYA 4J44A 3F7IA 4J3YA 4A0JA 3UIGA 4KJUA 4HY0A 2RAWA 1JD4A 1QBHA 4MTZA 3T6PA 2VSLA 4LGUA 1OXNA 1TW6A 1G73C 3UEHA 4KMNA 5C3KA 1NW9A 1TFTA 1M4MA 3UEDA 1F9XA 5C7CA 4EC4A 4WVTA 3GT9A 1F3HA 5C3HA 4J47A 3UIIA 3CLXA 3SIPE 1I3OE 1Q4QA 4A0NA 3CM7A 2UVLA 1JD5A 1TFQA 3HL5A 3UEGA 4J45A 1XOXA 5C84A 2I3HA 4HY5A 3UIJA 3MUPA 1E31A 1XB0A 4OXCA 2OPZA 4A0IA 4J48A 5C7BA 3UEFA 3F7GA 3UW5A 1JD6A 5C0LA 4LGEA 3M1DA 3UW4A 2VM5A 5C0KA 3D9TA 5C83A 4MU7A 4J46A 3EYLA 3UEIA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3M0A D;  2RAX A;  2QFA A;  4WVU A;  3UIK A;  4HY4 A;  4KJV A;  4EB9 A;  5C7D A;  4MTI A;  3UEE A;  3UEC A;  3SIQ A;  3OZ1 A;  1C9Q A;  1G3F A;  2POI A;  3UIH A;  3F7H A;  5C7A A;  1OY7 A;  1XB1 A;  2JK7 A;  1SE0 A;  4KMP A;  1SDZ A;  2POP B;  3CM2 A;  3D9U A;  4WVS A;  3M0D D;  3G76 A;  3GTA A;  2I3I A;  1OXQ A;  2QRA A;  2OPY A;  4J44 A;  3F7I A;  4J3Y A;  4A0J A;  3UIG A;  4KJU A;  4HY0 A;  2RAW A;  1JD4 A;  1QBH A;  4MTZ A;  3T6P A;  2VSL A;  4LGU A;  1OXN A;  1TW6 A;  1G73 C;  3UEH A;  4KMN A;  5C3K A;  1NW9 A;  1TFT A;  1M4M A;  3UED A;  1F9X A;  5C7C A;  4EC4 A;  4WVT A;  3GT9 A;  1F3H A;  5C3H A;  4J47 A;  3UII A;  3CLX A;  3SIP E;  1I3O E;  1Q4Q A;  4A0N A;  3CM7 A;  2UVL A;  1JD5 A;  1TFQ A;  3HL5 A;  3UEG A;  4J45 A;  1XOX A;  5C84 A;  2I3H A;  4HY5 A;  3UIJ A;  3MUP A;  1E31 A;  1XB0 A;  4OXC A;  2OPZ A;  4A0I A;  4J48 A;  5C7B A;  3UEF A;  3F7G A;  3UW5 A;  1JD6 A;  5C0L A;  4LGE A;  3M1D A;  3UW4 A;  2VM5 A;  5C0K A;  3D9T A;  5C83 A;  4MU7 A;  4J46 A;  3EYL A;  3UEI A; 
#chains in the Genus database with same CATH topology
 3M0A D;  2RAX A;  2QFA A;  4WVU A;  3UIK A;  4HY4 A;  4KJV A;  4EB9 A;  5C7D A;  4MTI A;  3UEE A;  3UEC A;  3SIQ A;  3OZ1 A;  1C9Q A;  1G3F A;  2POI A;  3UIH A;  3F7H A;  5C7A A;  1OY7 A;  1XB1 A;  2JK7 A;  1SE0 A;  4KMP A;  1SDZ A;  2POP B;  3CM2 A;  3D9U A;  4WVS A;  3M0D D;  3G76 A;  3GTA A;  2I3I A;  1OXQ A;  2QRA A;  2OPY A;  4J44 A;  3F7I A;  4J3Y A;  4A0J A;  3UIG A;  4KJU A;  4HY0 A;  2RAW A;  1JD4 A;  1QBH A;  4MTZ A;  3T6P A;  2VSL A;  4LGU A;  1OXN A;  1TW6 A;  1G73 C;  3UEH A;  4KMN A;  5C3K A;  1NW9 A;  1TFT A;  1M4M A;  3UED A;  1F9X A;  5C7C A;  4EC4 A;  4WVT A;  3GT9 A;  1F3H A;  5C3H A;  4J47 A;  3UII A;  3CLX A;  3SIP E;  1I3O E;  1Q4Q A;  4A0N A;  3CM7 A;  2UVL A;  1JD5 A;  1TFQ A;  3HL5 A;  3UEG A;  4J45 A;  1XOX A;  5C84 A;  2I3H A;  4HY5 A;  3UIJ A;  3MUP A;  1E31 A;  1XB0 A;  4OXC A;  2OPZ A;  4A0I A;  4J48 A;  5C7B A;  3UEF A;  3F7G A;  3UW5 A;  1JD6 A;  5C0L A;  4LGE A;  3M1D A;  3UW4 A;  2VM5 A;  5C0K A;  3D9T A;  5C83 A;  4MU7 A;  4J46 A;  3EYL A;  3UEI A; 
#chains in the Genus database with same CATH homology
 3M0A D;  2RAX A;  2QFA A;  4WVU A;  3UIK A;  4HY4 A;  4KJV A;  4EB9 A;  5C7D A;  4MTI A;  3UEE A;  3UEC A;  3SIQ A;  3OZ1 A;  1C9Q A;  1G3F A;  2POI A;  3UIH A;  3F7H A;  5C7A A;  1OY7 A;  1XB1 A;  2JK7 A;  1SE0 A;  4KMP A;  1SDZ A;  2POP B;  3CM2 A;  3D9U A;  4WVS A;  3M0D D;  3G76 A;  3GTA A;  2I3I A;  1OXQ A;  2QRA A;  2OPY A;  4J44 A;  3F7I A;  4J3Y A;  4A0J A;  3UIG A;  4KJU A;  4HY0 A;  2RAW A;  1JD4 A;  1QBH A;  4MTZ A;  3T6P A;  2VSL A;  4LGU A;  1OXN A;  1TW6 A;  1G73 C;  3UEH A;  4KMN A;  5C3K A;  1NW9 A;  1TFT A;  1M4M A;  3UED A;  1F9X A;  5C7C A;  4EC4 A;  4WVT A;  3GT9 A;  1F3H A;  5C3H A;  4J47 A;  3UII A;  3CLX A;  3SIP E;  1I3O E;  1Q4Q A;  4A0N A;  3CM7 A;  2UVL A;  1JD5 A;  1TFQ A;  3HL5 A;  3UEG A;  4J45 A;  1XOX A;  5C84 A;  2I3H A;  4HY5 A;  3UIJ A;  3MUP A;  1E31 A;  1XB0 A;  4OXC A;  2OPZ A;  4A0I A;  4J48 A;  5C7B A;  3UEF A;  3F7G A;  3UW5 A;  1JD6 A;  5C0L A;  4LGE A;  3M1D A;  3UW4 A;  2VM5 A;  5C0K A;  3D9T A;  5C83 A;  4MU7 A;  4J46 A;  3EYL A;  3UEI A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...