3G76A

Crystal structure of xiap-bir3 in complex with a bivalent compound
Total Genus 22
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
22
sequence length
97
structure length
97
Chain Sequence
NSTNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Structural basis for bivalent smac-mimetics recognition in the IAP protein family
pubmed doi rcsb
molecule tags Ligase
source organism Homo sapiens
molecule keywords Baculoviral IAP repeat-containing protein 4
total genus 22
structure length 97
sequence length 97
chains with identical sequence B, C, D, E, F, G, H
ec nomenclature ec 2.3.2.27: RING-type E3 ubiquitin transferase.
pdb deposition date 2009-02-09

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00653 BIR Inhibitor of Apoptosis domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.1170.10 Mainly Alpha Orthogonal Bundle Inhibitor Of Apoptosis Protein (2mihbC-IAP-1); Chain A Inhibitor Of Apoptosis Protein (2mihbC-IAP-1); Chain A 3g76A00
3GT9A 3OZ1A 4OXCA 3SIQA 3D9UA 3F7HA 2OPYA 4KJVA 2RAXA 3M0AD 4KJUA 3CM2A 4KMNA 4A0IA 1JD6A 1OY7A 3M1DA 4MU7A 2POIA 1OXNA 5C3KA 5C7AA 4EB9A 3G76A 4LGEA 1SE0A 3UEDA 4WVSA 5C84A 3UEHA 1XB0A 3UECA 3CLXA 4J44A 1M4MA 1Q4QA 3UIIA 1SDZA 2RAWA 1XOXA 4HY5A 1F3HA 4HY0A 1TFQA 1C9QA 4MTIA 1F9XA 3F7GA 4KMPA 2QFAA 3UIKA 3UIJA 2OPZA 2VSLA 3EYLA 4MTZA 3SIPE 3UW4A 4HY4A 5C83A 5C7DA 1E31A 5C7CA 1XB1A 3MUPA 1JD5A 2VM5A 4J3YA 1OXQA 3D9TA 4WVUA 4J45A 3F7IA 1TFTA 2QRAA 5C7BA 3M0DD 5C0LA 4J48A 1G3FA 3UIHA 1JD4A 5C0KA 3UEFA 4LGUA 3T6PA 2UVLA 4A0JA 3GTAA 1NW9A 1G73C 2I3IA 1I3OE 4EC4A 2POPB 1QBHA 2JK7A 3UIGA 3UEGA 3UEEA 4WVTA 2I3HA 3UEIA 4J47A 1TW6A 4J46A 3UW5A 5C3HA 3HL5A 3CM7A 4A0NA
chains in the Genus database with same CATH superfamily
3GT9A 3OZ1A 4OXCA 3SIQA 3D9UA 3F7HA 2OPYA 4KJVA 2RAXA 3M0AD 4KJUA 3CM2A 4KMNA 4A0IA 1JD6A 1OY7A 3M1DA 4MU7A 2POIA 1OXNA 5C3KA 5C7AA 4EB9A 3G76A 4LGEA 1SE0A 3UEDA 4WVSA 5C84A 3UEHA 1XB0A 3UECA 3CLXA 4J44A 1M4MA 1Q4QA 3UIIA 1SDZA 2RAWA 1XOXA 4HY5A 1F3HA 4HY0A 1TFQA 1C9QA 4MTIA 1F9XA 3F7GA 4KMPA 2QFAA 3UIKA 3UIJA 2OPZA 2VSLA 3EYLA 4MTZA 3SIPE 3UW4A 4HY4A 5C83A 5C7DA 1E31A 5C7CA 1XB1A 3MUPA 1JD5A 2VM5A 4J3YA 1OXQA 3D9TA 4WVUA 4J45A 3F7IA 1TFTA 2QRAA 5C7BA 3M0DD 5C0LA 4J48A 1G3FA 3UIHA 1JD4A 5C0KA 3UEFA 4LGUA 3T6PA 2UVLA 4A0JA 3GTAA 1NW9A 1G73C 2I3IA 1I3OE 4EC4A 2POPB 1QBHA 2JK7A 3UIGA 3UEGA 3UEEA 4WVTA 2I3HA 3UEIA 4J47A 1TW6A 4J46A 3UW5A 5C3HA 3HL5A 3CM7A 4A0NA
chains in the Genus database with same CATH topology
3GT9A 3OZ1A 4OXCA 3SIQA 3D9UA 3F7HA 2OPYA 4KJVA 2RAXA 3M0AD 4KJUA 3CM2A 4KMNA 4A0IA 1JD6A 1OY7A 3M1DA 4MU7A 2POIA 1OXNA 5C3KA 5C7AA 4EB9A 3G76A 4LGEA 1SE0A 3UEDA 4WVSA 5C84A 3UEHA 1XB0A 3UECA 3CLXA 4J44A 1M4MA 1Q4QA 3UIIA 1SDZA 2RAWA 1XOXA 4HY5A 1F3HA 4HY0A 1TFQA 1C9QA 4MTIA 1F9XA 3F7GA 4KMPA 2QFAA 3UIKA 3UIJA 2OPZA 2VSLA 3EYLA 4MTZA 3SIPE 3UW4A 4HY4A 5C83A 5C7DA 1E31A 5C7CA 1XB1A 3MUPA 1JD5A 2VM5A 4J3YA 1OXQA 3D9TA 4WVUA 4J45A 3F7IA 1TFTA 2QRAA 5C7BA 3M0DD 5C0LA 4J48A 1G3FA 3UIHA 1JD4A 5C0KA 3UEFA 4LGUA 3T6PA 2UVLA 4A0JA 3GTAA 1NW9A 1G73C 2I3IA 1I3OE 4EC4A 2POPB 1QBHA 2JK7A 3UIGA 3UEGA 3UEEA 4WVTA 2I3HA 3UEIA 4J47A 1TW6A 4J46A 3UW5A 5C3HA 3HL5A 3CM7A 4A0NA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3GT9 A;  3OZ1 A;  4OXC A;  3SIQ A;  3D9U A;  3F7H A;  2OPY A;  4KJV A;  2RAX A;  3M0A D;  4KJU A;  3CM2 A;  4KMN A;  4A0I A;  1JD6 A;  1OY7 A;  3M1D A;  4MU7 A;  2POI A;  1OXN A;  5C3K A;  5C7A A;  4EB9 A;  3G76 A;  4LGE A;  1SE0 A;  3UED A;  4WVS A;  5C84 A;  3UEH A;  1XB0 A;  3UEC A;  3CLX A;  4J44 A;  1M4M A;  1Q4Q A;  3UII A;  1SDZ A;  2RAW A;  1XOX A;  4HY5 A;  1F3H A;  4HY0 A;  1TFQ A;  1C9Q A;  4MTI A;  1F9X A;  3F7G A;  4KMP A;  2QFA A;  3UIK A;  3UIJ A;  2OPZ A;  2VSL A;  3EYL A;  4MTZ A;  3SIP E;  3UW4 A;  4HY4 A;  5C83 A;  5C7D A;  1E31 A;  5C7C A;  1XB1 A;  3MUP A;  1JD5 A;  2VM5 A;  4J3Y A;  1OXQ A;  3D9T A;  4WVU A;  4J45 A;  3F7I A;  1TFT A;  2QRA A;  5C7B A;  3M0D D;  5C0L A;  4J48 A;  1G3F A;  3UIH A;  1JD4 A;  5C0K A;  3UEF A;  4LGU A;  3T6P A;  2UVL A;  4A0J A;  3GTA A;  1NW9 A;  1G73 C;  2I3I A;  1I3O E;  4EC4 A;  2POP B;  1QBH A;  2JK7 A;  3UIG A;  3UEG A;  3UEE A;  4WVT A;  2I3H A;  3UEI A;  4J47 A;  1TW6 A;  4J46 A;  3UW5 A;  5C3H A;  3HL5 A;  3CM7 A;  4A0N A; 
#chains in the Genus database with same CATH topology
 3GT9 A;  3OZ1 A;  4OXC A;  3SIQ A;  3D9U A;  3F7H A;  2OPY A;  4KJV A;  2RAX A;  3M0A D;  4KJU A;  3CM2 A;  4KMN A;  4A0I A;  1JD6 A;  1OY7 A;  3M1D A;  4MU7 A;  2POI A;  1OXN A;  5C3K A;  5C7A A;  4EB9 A;  3G76 A;  4LGE A;  1SE0 A;  3UED A;  4WVS A;  5C84 A;  3UEH A;  1XB0 A;  3UEC A;  3CLX A;  4J44 A;  1M4M A;  1Q4Q A;  3UII A;  1SDZ A;  2RAW A;  1XOX A;  4HY5 A;  1F3H A;  4HY0 A;  1TFQ A;  1C9Q A;  4MTI A;  1F9X A;  3F7G A;  4KMP A;  2QFA A;  3UIK A;  3UIJ A;  2OPZ A;  2VSL A;  3EYL A;  4MTZ A;  3SIP E;  3UW4 A;  4HY4 A;  5C83 A;  5C7D A;  1E31 A;  5C7C A;  1XB1 A;  3MUP A;  1JD5 A;  2VM5 A;  4J3Y A;  1OXQ A;  3D9T A;  4WVU A;  4J45 A;  3F7I A;  1TFT A;  2QRA A;  5C7B A;  3M0D D;  5C0L A;  4J48 A;  1G3F A;  3UIH A;  1JD4 A;  5C0K A;  3UEF A;  4LGU A;  3T6P A;  2UVL A;  4A0J A;  3GTA A;  1NW9 A;  1G73 C;  2I3I A;  1I3O E;  4EC4 A;  2POP B;  1QBH A;  2JK7 A;  3UIG A;  3UEG A;  3UEE A;  4WVT A;  2I3H A;  3UEI A;  4J47 A;  1TW6 A;  4J46 A;  3UW5 A;  5C3H A;  3HL5 A;  3CM7 A;  4A0N A; 
#chains in the Genus database with same CATH homology
 3GT9 A;  3OZ1 A;  4OXC A;  3SIQ A;  3D9U A;  3F7H A;  2OPY A;  4KJV A;  2RAX A;  3M0A D;  4KJU A;  3CM2 A;  4KMN A;  4A0I A;  1JD6 A;  1OY7 A;  3M1D A;  4MU7 A;  2POI A;  1OXN A;  5C3K A;  5C7A A;  4EB9 A;  3G76 A;  4LGE A;  1SE0 A;  3UED A;  4WVS A;  5C84 A;  3UEH A;  1XB0 A;  3UEC A;  3CLX A;  4J44 A;  1M4M A;  1Q4Q A;  3UII A;  1SDZ A;  2RAW A;  1XOX A;  4HY5 A;  1F3H A;  4HY0 A;  1TFQ A;  1C9Q A;  4MTI A;  1F9X A;  3F7G A;  4KMP A;  2QFA A;  3UIK A;  3UIJ A;  2OPZ A;  2VSL A;  3EYL A;  4MTZ A;  3SIP E;  3UW4 A;  4HY4 A;  5C83 A;  5C7D A;  1E31 A;  5C7C A;  1XB1 A;  3MUP A;  1JD5 A;  2VM5 A;  4J3Y A;  1OXQ A;  3D9T A;  4WVU A;  4J45 A;  3F7I A;  1TFT A;  2QRA A;  5C7B A;  3M0D D;  5C0L A;  4J48 A;  1G3F A;  3UIH A;  1JD4 A;  5C0K A;  3UEF A;  4LGU A;  3T6P A;  2UVL A;  4A0J A;  3GTA A;  1NW9 A;  1G73 C;  2I3I A;  1I3O E;  4EC4 A;  2POP B;  1QBH A;  2JK7 A;  3UIG A;  3UEG A;  3UEE A;  4WVT A;  2I3H A;  3UEI A;  4J47 A;  1TW6 A;  4J46 A;  3UW5 A;  5C3H A;  3HL5 A;  3CM7 A;  4A0N A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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