3GTAA

Structure of an ml-iap/xiap chimera bound to a peptidomimetic
Total Genus 23
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
23
sequence length
90
structure length
90
Chain Sequence
GPAFPGMGSEELRLASFYDWPLTAEVPPELLAAAGFFHTGHQDKVRCFFCYGGLQSWKRGDDPWTEHAKWFPGCQFLLRSKGQEYINNIH
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Antagonists of inhibitor of apoptosis proteins based on thiazole amide isosteres.
pubmed doi rcsb
molecule tags Apoptosis
source organism Homo sapiens
molecule keywords Baculoviral IAP repeat-containing 7
total genus 23
structure length 90
sequence length 90
chains with identical sequence B
ec nomenclature ec 2.3.2.27: RING-type E3 ubiquitin transferase.
pdb deposition date 2009-03-27

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00653 BIR Inhibitor of Apoptosis domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.1170.10 Mainly Alpha Orthogonal Bundle Inhibitor Of Apoptosis Protein (2mihbC-IAP-1); Chain A Inhibitor Of Apoptosis Protein (2mihbC-IAP-1); Chain A 3gtaA00
4KJVA 5C7AA 3D9TA 1F3HA 4J45A 3UW5A 5C7CA 1G3FA 1Q4QA 2VSLA 4A0JA 2I3IA 3UIIA 4OXCA 3UIGA 1OXNA 2QFAA 3SIPE 4EB9A 3G76A 4EC4A 3D9UA 3M0DD 5C7BA 4LGEA 3GT9A 1OXQA 3MUPA 4KMNA 5C83A 2OPYA 1TFQA 1I3OE 4WVUA 4KMPA 3T6PA 1G73C 2QRAA 4A0IA 4HY0A 3UIHA 1NW9A 1TW6A 4MU7A 4MTIA 3SIQA 1JD6A 3HL5A 1XB1A 3UEGA 3UEIA 4J47A 3UEFA 3CLXA 2RAXA 4J3YA 5C84A 5C0KA 3UEEA 3F7IA 4J46A 3UECA 3EYLA 1M4MA 1JD4A 4KJUA 3F7HA 5C3KA 2JK7A 3CM2A 4MTZA 3UEHA 3UW4A 1TFTA 2I3HA 4WVTA 1C9QA 5C0LA 1XB0A 3CM7A 3M0AD 2VM5A 1XOXA 4HY5A 3M1DA 2OPZA 4J44A 4HY4A 3GTAA 1OY7A 1JD5A 3UEDA 1E31A 3F7GA 3OZ1A 4J48A 4LGUA 2POPB 2POIA 3UIKA 3UIJA 4WVSA 1SE0A 5C7DA 2UVLA 1SDZA 1F9XA 4A0NA 2RAWA 5C3HA 1QBHA
chains in the Genus database with same CATH superfamily
4KJVA 5C7AA 3D9TA 1F3HA 4J45A 3UW5A 5C7CA 1G3FA 1Q4QA 2VSLA 4A0JA 2I3IA 3UIIA 4OXCA 3UIGA 1OXNA 2QFAA 3SIPE 4EB9A 3G76A 4EC4A 3D9UA 3M0DD 5C7BA 4LGEA 3GT9A 1OXQA 3MUPA 4KMNA 5C83A 2OPYA 1TFQA 1I3OE 4WVUA 4KMPA 3T6PA 1G73C 2QRAA 4A0IA 4HY0A 3UIHA 1NW9A 1TW6A 4MU7A 4MTIA 3SIQA 1JD6A 3HL5A 1XB1A 3UEGA 3UEIA 4J47A 3UEFA 3CLXA 2RAXA 4J3YA 5C84A 5C0KA 3UEEA 3F7IA 4J46A 3UECA 3EYLA 1M4MA 1JD4A 4KJUA 3F7HA 5C3KA 2JK7A 3CM2A 4MTZA 3UEHA 3UW4A 1TFTA 2I3HA 4WVTA 1C9QA 5C0LA 1XB0A 3CM7A 3M0AD 2VM5A 1XOXA 4HY5A 3M1DA 2OPZA 4J44A 4HY4A 3GTAA 1OY7A 1JD5A 3UEDA 1E31A 3F7GA 3OZ1A 4J48A 4LGUA 2POPB 2POIA 3UIKA 3UIJA 4WVSA 1SE0A 5C7DA 2UVLA 1SDZA 1F9XA 4A0NA 2RAWA 5C3HA 1QBHA
chains in the Genus database with same CATH topology
4KJVA 5C7AA 3D9TA 1F3HA 4J45A 3UW5A 5C7CA 1G3FA 1Q4QA 2VSLA 4A0JA 2I3IA 3UIIA 4OXCA 3UIGA 1OXNA 2QFAA 3SIPE 4EB9A 3G76A 4EC4A 3D9UA 3M0DD 5C7BA 4LGEA 3GT9A 1OXQA 3MUPA 4KMNA 5C83A 2OPYA 1TFQA 1I3OE 4WVUA 4KMPA 3T6PA 1G73C 2QRAA 4A0IA 4HY0A 3UIHA 1NW9A 1TW6A 4MU7A 4MTIA 3SIQA 1JD6A 3HL5A 1XB1A 3UEGA 3UEIA 4J47A 3UEFA 3CLXA 2RAXA 4J3YA 5C84A 5C0KA 3UEEA 3F7IA 4J46A 3UECA 3EYLA 1M4MA 1JD4A 4KJUA 3F7HA 5C3KA 2JK7A 3CM2A 4MTZA 3UEHA 3UW4A 1TFTA 2I3HA 4WVTA 1C9QA 5C0LA 1XB0A 3CM7A 3M0AD 2VM5A 1XOXA 4HY5A 3M1DA 2OPZA 4J44A 4HY4A 3GTAA 1OY7A 1JD5A 3UEDA 1E31A 3F7GA 3OZ1A 4J48A 4LGUA 2POPB 2POIA 3UIKA 3UIJA 4WVSA 1SE0A 5C7DA 2UVLA 1SDZA 1F9XA 4A0NA 2RAWA 5C3HA 1QBHA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4KJV A;  5C7A A;  3D9T A;  1F3H A;  4J45 A;  3UW5 A;  5C7C A;  1G3F A;  1Q4Q A;  2VSL A;  4A0J A;  2I3I A;  3UII A;  4OXC A;  3UIG A;  1OXN A;  2QFA A;  3SIP E;  4EB9 A;  3G76 A;  4EC4 A;  3D9U A;  3M0D D;  5C7B A;  4LGE A;  3GT9 A;  1OXQ A;  3MUP A;  4KMN A;  5C83 A;  2OPY A;  1TFQ A;  1I3O E;  4WVU A;  4KMP A;  3T6P A;  1G73 C;  2QRA A;  4A0I A;  4HY0 A;  3UIH A;  1NW9 A;  1TW6 A;  4MU7 A;  4MTI A;  3SIQ A;  1JD6 A;  3HL5 A;  1XB1 A;  3UEG A;  3UEI A;  4J47 A;  3UEF A;  3CLX A;  2RAX A;  4J3Y A;  5C84 A;  5C0K A;  3UEE A;  3F7I A;  4J46 A;  3UEC A;  3EYL A;  1M4M A;  1JD4 A;  4KJU A;  3F7H A;  5C3K A;  2JK7 A;  3CM2 A;  4MTZ A;  3UEH A;  3UW4 A;  1TFT A;  2I3H A;  4WVT A;  1C9Q A;  5C0L A;  1XB0 A;  3CM7 A;  3M0A D;  2VM5 A;  1XOX A;  4HY5 A;  3M1D A;  2OPZ A;  4J44 A;  4HY4 A;  3GTA A;  1OY7 A;  1JD5 A;  3UED A;  1E31 A;  3F7G A;  3OZ1 A;  4J48 A;  4LGU A;  2POP B;  2POI A;  3UIK A;  3UIJ A;  4WVS A;  1SE0 A;  5C7D A;  2UVL A;  1SDZ A;  1F9X A;  4A0N A;  2RAW A;  5C3H A;  1QBH A; 
#chains in the Genus database with same CATH topology
 4KJV A;  5C7A A;  3D9T A;  1F3H A;  4J45 A;  3UW5 A;  5C7C A;  1G3F A;  1Q4Q A;  2VSL A;  4A0J A;  2I3I A;  3UII A;  4OXC A;  3UIG A;  1OXN A;  2QFA A;  3SIP E;  4EB9 A;  3G76 A;  4EC4 A;  3D9U A;  3M0D D;  5C7B A;  4LGE A;  3GT9 A;  1OXQ A;  3MUP A;  4KMN A;  5C83 A;  2OPY A;  1TFQ A;  1I3O E;  4WVU A;  4KMP A;  3T6P A;  1G73 C;  2QRA A;  4A0I A;  4HY0 A;  3UIH A;  1NW9 A;  1TW6 A;  4MU7 A;  4MTI A;  3SIQ A;  1JD6 A;  3HL5 A;  1XB1 A;  3UEG A;  3UEI A;  4J47 A;  3UEF A;  3CLX A;  2RAX A;  4J3Y A;  5C84 A;  5C0K A;  3UEE A;  3F7I A;  4J46 A;  3UEC A;  3EYL A;  1M4M A;  1JD4 A;  4KJU A;  3F7H A;  5C3K A;  2JK7 A;  3CM2 A;  4MTZ A;  3UEH A;  3UW4 A;  1TFT A;  2I3H A;  4WVT A;  1C9Q A;  5C0L A;  1XB0 A;  3CM7 A;  3M0A D;  2VM5 A;  1XOX A;  4HY5 A;  3M1D A;  2OPZ A;  4J44 A;  4HY4 A;  3GTA A;  1OY7 A;  1JD5 A;  3UED A;  1E31 A;  3F7G A;  3OZ1 A;  4J48 A;  4LGU A;  2POP B;  2POI A;  3UIK A;  3UIJ A;  4WVS A;  1SE0 A;  5C7D A;  2UVL A;  1SDZ A;  1F9X A;  4A0N A;  2RAW A;  5C3H A;  1QBH A; 
#chains in the Genus database with same CATH homology
 4KJV A;  5C7A A;  3D9T A;  1F3H A;  4J45 A;  3UW5 A;  5C7C A;  1G3F A;  1Q4Q A;  2VSL A;  4A0J A;  2I3I A;  3UII A;  4OXC A;  3UIG A;  1OXN A;  2QFA A;  3SIP E;  4EB9 A;  3G76 A;  4EC4 A;  3D9U A;  3M0D D;  5C7B A;  4LGE A;  3GT9 A;  1OXQ A;  3MUP A;  4KMN A;  5C83 A;  2OPY A;  1TFQ A;  1I3O E;  4WVU A;  4KMP A;  3T6P A;  1G73 C;  2QRA A;  4A0I A;  4HY0 A;  3UIH A;  1NW9 A;  1TW6 A;  4MU7 A;  4MTI A;  3SIQ A;  1JD6 A;  3HL5 A;  1XB1 A;  3UEG A;  3UEI A;  4J47 A;  3UEF A;  3CLX A;  2RAX A;  4J3Y A;  5C84 A;  5C0K A;  3UEE A;  3F7I A;  4J46 A;  3UEC A;  3EYL A;  1M4M A;  1JD4 A;  4KJU A;  3F7H A;  5C3K A;  2JK7 A;  3CM2 A;  4MTZ A;  3UEH A;  3UW4 A;  1TFT A;  2I3H A;  4WVT A;  1C9Q A;  5C0L A;  1XB0 A;  3CM7 A;  3M0A D;  2VM5 A;  1XOX A;  4HY5 A;  3M1D A;  2OPZ A;  4J44 A;  4HY4 A;  3GTA A;  1OY7 A;  1JD5 A;  3UED A;  1E31 A;  3F7G A;  3OZ1 A;  4J48 A;  4LGU A;  2POP B;  2POI A;  3UIK A;  3UIJ A;  4WVS A;  1SE0 A;  5C7D A;  2UVL A;  1SDZ A;  1F9X A;  4A0N A;  2RAW A;  5C3H A;  1QBH A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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