3IT7 | Genus

Total Genus 48

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus	48
sequence length	182
structure length	182
Chain Sequence	APPSNLMQLPWRQGYSWQPNGAHSNTGSGYPYSSFDASYDWPRWGSATYSVVAAHAGTVRVLSRCQVRVTHPSGWATNYYHMDQIQVSNGQQVSADTKLGVYAGNINTALCEGGSSTGPHLHFSLLYNGAFVSLQGASFGPYRINVGTSNYDNDCRRYYFYNQSAGTTHCAFRPLYNPGLAL

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

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After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Genus data interpretation

Chord Diagram

molecule tags	Hydrolase
publication title	Crystal structure of the LasA virulence factor from Pseudomonas aeruginosa: substrate specificity and mechanism of M23 metallopeptidases. pubmed doi rcsb
molecule keywords	Protease lasA
total genus	48
structure length	182
sequence length	182
chains with identical sequence	B
ec nomenclature	ec 3.4.24.-:
pdb deposition date	2009-08-27

pfam database annotations

chain	Pfam Accession Code	Pfam Family Identifier	Pfam Description
A	PF01551	Peptidase_M23	Peptidase family M23

Image from the rcsb pdb (www.rcsb.org)

cath code	Class	Architecture	Topology	Homology	Domain
2.70.70.10	Mainly Beta	Distorted Sandwich	Glucose Permease (Domain IIA)	Glucose Permease (Domain IIA)	3it7A00

3NYYA 4QP5A 2GU1A 2MP0B 3IT7A 1F3GA 2F3GA 4RNZA 2HSIA 3CSQA 1GLBF 3OURB 5B0HA 3TUFB 1GLCF 1QWYA 4RNYA 4BH5A 1GLEF 1AX3A 3IT5A 1F3ZA 1GPRA 1GLAF 3UZ0B 1O2FA 1GLDF 1GGRA 2B44A 2B0PA 4QPBA 2B13A 4ZYBA 5KVPA 4JBWM 3SLUA 4LXCA 2GPRA
chains in the Genus database with same CATH superfamily

#chains in the Genus database with same CATH superfamily
 3NYY A;  4QP5 A;  2GU1 A;  2MP0 B;  3IT7 A;  1F3G A;  2F3G A;  4RNZ A;  2HSI A;  3CSQ A;  1GLB F;  3OUR B;  5B0H A;  3TUF B;  1GLC F;  1QWY A;  4RNY A;  4BH5 A;  1GLE F;  1AX3 A;  3IT5 A;  1F3Z A;  1GPR A;  1GLA F;  3UZ0 B;  1O2F A;  1GLD F;  1GGR A;  2B44 A;  2B0P A;  4QPB A;  2B13 A;  4ZYB A;  5KVP A;  4JBW M;  3SLU A;  4LXC A;  2GPR A; 
#chains in the Genus database with same CATH topology
 3NYY A;  4QP5 A;  2GU1 A;  2MP0 B;  3IT7 A;  1F3G A;  2F3G A;  4RNZ A;  2HSI A;  3CSQ A;  1GLB F;  3OUR B;  5B0H A;  3TUF B;  1GLC F;  1QWY A;  4RNY A;  4BH5 A;  1GLE F;  1AX3 A;  3IT5 A;  1F3Z A;  1GPR A;  1GLA F;  3UZ0 B;  1O2F A;  1GLD F;  1GGR A;  2B44 A;  2B0P A;  4QPB A;  2B13 A;  4ZYB A;  5KVP A;  4JBW M;  3SLU A;  4LXC A;  2GPR A; 
#chains in the Genus database with same CATH homology
 3NYY A;  4QP5 A;  2GU1 A;  2MP0 B;  3IT7 A;  1F3G A;  2F3G A;  4RNZ A;  2HSI A;  3CSQ A;  1GLB F;  3OUR B;  5B0H A;  3TUF B;  1GLC F;  1QWY A;  4RNY A;  4BH5 A;  1GLE F;  1AX3 A;  3IT5 A;  1F3Z A;  1GPR A;  1GLA F;  3UZ0 B;  1O2F A;  1GLD F;  1GGR A;  2B44 A;  2B0P A;  4QPB A;  2B13 A;  4ZYB A;  5KVP A;  4JBW M;  3SLU A;  4LXC A;  2GPR A;

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similar chains in the Genus database (?% sequence similarity)

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similar chains in the pdb database (?% sequence similarity)

#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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3IT7A

Total Genus

sequence length

structure length

Chain Sequence

Structure visualization

Chord Diagram

connected with : NaN

pfam database annotations