3IT7A

Crystal structure of the lasa virulence factor from pseudomonas aeruginosa
Total Genus 48
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
48
sequence length
182
structure length
182
Chain Sequence
APPSNLMQLPWRQGYSWQPNGAHSNTGSGYPYSSFDASYDWPRWGSATYSVVAAHAGTVRVLSRCQVRVTHPSGWATNYYHMDQIQVSNGQQVSADTKLGVYAGNINTALCEGGSSTGPHLHFSLLYNGAFVSLQGASFGPYRINVGTSNYDNDCRRYYFYNQSAGTTHCAFRPLYNPGLAL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal structure of the LasA virulence factor from Pseudomonas aeruginosa: substrate specificity and mechanism of M23 metallopeptidases.
pubmed doi rcsb
molecule tags Hydrolase
molecule keywords Protease lasA
total genus 48
structure length 182
sequence length 182
chains with identical sequence B
ec nomenclature ec 3.4.24.-:
pdb deposition date 2009-08-27

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01551 Peptidase_M23 Peptidase family M23
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.70.70.10 Mainly Beta Distorted Sandwich Glucose Permease (Domain IIA) Glucose Permease (Domain IIA) 3it7A00
1GLEF 4RNYA 3TUFB 5KVPA 1GPRA 2GPRA 4BH5A 4QP5A 3CSQA 2B44A 5B0HA 2F3GA 1GLCF 1O2FA 1GGRA 2MP0B 3IT5A 1GLBF 4ZYBA 2B13A 1GLAF 2B0PA 3UZ0B 4RNZA 1AX3A 2HSIA 1GLDF 1F3GA 4QPBA 1QWYA 1F3ZA 3SLUA 3NYYA 2GU1A 4LXCA 4JBWM 3IT7A 3OURB
chains in the Genus database with same CATH superfamily
1GLEF 4RNYA 3TUFB 5KVPA 1GPRA 2GPRA 4BH5A 4QP5A 3CSQA 2B44A 5B0HA 2F3GA 1GLCF 1O2FA 1GGRA 2MP0B 3IT5A 1GLBF 4ZYBA 2B13A 1GLAF 2B0PA 3UZ0B 4RNZA 1AX3A 2HSIA 1GLDF 1F3GA 4QPBA 1QWYA 1F3ZA 3SLUA 3NYYA 2GU1A 4LXCA 4JBWM 3IT7A 3OURB
chains in the Genus database with same CATH topology
1GLEF 4RNYA 3TUFB 5KVPA 1GPRA 2GPRA 4BH5A 4QP5A 3CSQA 2B44A 5B0HA 2F3GA 1GLCF 1O2FA 1GGRA 2MP0B 3IT5A 1GLBF 4ZYBA 2B13A 1GLAF 2B0PA 3UZ0B 4RNZA 1AX3A 2HSIA 1GLDF 1F3GA 4QPBA 1QWYA 1F3ZA 3SLUA 3NYYA 2GU1A 4LXCA 4JBWM 3IT7A 3OURB
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1GLE F;  4RNY A;  3TUF B;  5KVP A;  1GPR A;  2GPR A;  4BH5 A;  4QP5 A;  3CSQ A;  2B44 A;  5B0H A;  2F3G A;  1GLC F;  1O2F A;  1GGR A;  2MP0 B;  3IT5 A;  1GLB F;  4ZYB A;  2B13 A;  1GLA F;  2B0P A;  3UZ0 B;  4RNZ A;  1AX3 A;  2HSI A;  1GLD F;  1F3G A;  4QPB A;  1QWY A;  1F3Z A;  3SLU A;  3NYY A;  2GU1 A;  4LXC A;  4JBW M;  3IT7 A;  3OUR B; 
#chains in the Genus database with same CATH topology
 1GLE F;  4RNY A;  3TUF B;  5KVP A;  1GPR A;  2GPR A;  4BH5 A;  4QP5 A;  3CSQ A;  2B44 A;  5B0H A;  2F3G A;  1GLC F;  1O2F A;  1GGR A;  2MP0 B;  3IT5 A;  1GLB F;  4ZYB A;  2B13 A;  1GLA F;  2B0P A;  3UZ0 B;  4RNZ A;  1AX3 A;  2HSI A;  1GLD F;  1F3G A;  4QPB A;  1QWY A;  1F3Z A;  3SLU A;  3NYY A;  2GU1 A;  4LXC A;  4JBW M;  3IT7 A;  3OUR B; 
#chains in the Genus database with same CATH homology
 1GLE F;  4RNY A;  3TUF B;  5KVP A;  1GPR A;  2GPR A;  4BH5 A;  4QP5 A;  3CSQ A;  2B44 A;  5B0H A;  2F3G A;  1GLC F;  1O2F A;  1GGR A;  2MP0 B;  3IT5 A;  1GLB F;  4ZYB A;  2B13 A;  1GLA F;  2B0P A;  3UZ0 B;  4RNZ A;  1AX3 A;  2HSI A;  1GLD F;  1F3G A;  4QPB A;  1QWY A;  1F3Z A;  3SLU A;  3NYY A;  2GU1 A;  4LXC A;  4JBW M;  3IT7 A;  3OUR B; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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