3IT7A

Crystal structure of the lasa virulence factor from pseudomonas aeruginosa
Total Genus 48
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
48
sequence length
182
structure length
182
Chain Sequence
APPSNLMQLPWRQGYSWQPNGAHSNTGSGYPYSSFDASYDWPRWGSATYSVVAAHAGTVRVLSRCQVRVTHPSGWATNYYHMDQIQVSNGQQVSADTKLGVYAGNINTALCEGGSSTGPHLHFSLLYNGAFVSLQGASFGPYRINVGTSNYDNDCRRYYFYNQSAGTTHCAFRPLYNPGLAL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Hydrolase
publication title Crystal structure of the LasA virulence factor from Pseudomonas aeruginosa: substrate specificity and mechanism of M23 metallopeptidases.
pubmed doi rcsb
molecule keywords Protease lasA
total genus 48
structure length 182
sequence length 182
chains with identical sequence B
ec nomenclature ec 3.4.24.-:
pdb deposition date 2009-08-27

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01551 Peptidase_M23 Peptidase family M23
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.70.70.10 Mainly Beta Distorted Sandwich Glucose Permease (Domain IIA) Glucose Permease (Domain IIA) 3it7A00
4RNYA 4JBWM 1GGRA 4RNZA 2F3GA 3IT5A 1GLCF 4QPBA 3SLUA 1GPRA 4QP5A 3CSQA 1GLAF 5KVPA 1F3GA 3NYYA 1GLBF 1F3ZA 2B0PA 4BH5A 4ZYBA 2GPRA 1AX3A 5B0HA 2MP0B 2B44A 1GLEF 3IT7A 3OURB 1O2FA 2GU1A 1QWYA 1GLDF 3UZ0B 2B13A 4LXCA 2HSIA 3TUFB
chains in the Genus database with same CATH superfamily
4RNYA 4JBWM 1GGRA 4RNZA 2F3GA 3IT5A 1GLCF 4QPBA 3SLUA 1GPRA 4QP5A 3CSQA 1GLAF 5KVPA 1F3GA 3NYYA 1GLBF 1F3ZA 2B0PA 4BH5A 4ZYBA 2GPRA 1AX3A 5B0HA 2MP0B 2B44A 1GLEF 3IT7A 3OURB 1O2FA 2GU1A 1QWYA 1GLDF 3UZ0B 2B13A 4LXCA 2HSIA 3TUFB
chains in the Genus database with same CATH topology
4RNYA 4JBWM 1GGRA 4RNZA 2F3GA 3IT5A 1GLCF 4QPBA 3SLUA 1GPRA 4QP5A 3CSQA 1GLAF 5KVPA 1F3GA 3NYYA 1GLBF 1F3ZA 2B0PA 4BH5A 4ZYBA 2GPRA 1AX3A 5B0HA 2MP0B 2B44A 1GLEF 3IT7A 3OURB 1O2FA 2GU1A 1QWYA 1GLDF 3UZ0B 2B13A 4LXCA 2HSIA 3TUFB
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4RNY A;  4JBW M;  1GGR A;  4RNZ A;  2F3G A;  3IT5 A;  1GLC F;  4QPB A;  3SLU A;  1GPR A;  4QP5 A;  3CSQ A;  1GLA F;  5KVP A;  1F3G A;  3NYY A;  1GLB F;  1F3Z A;  2B0P A;  4BH5 A;  4ZYB A;  2GPR A;  1AX3 A;  5B0H A;  2MP0 B;  2B44 A;  1GLE F;  3IT7 A;  3OUR B;  1O2F A;  2GU1 A;  1QWY A;  1GLD F;  3UZ0 B;  2B13 A;  4LXC A;  2HSI A;  3TUF B; 
#chains in the Genus database with same CATH topology
 4RNY A;  4JBW M;  1GGR A;  4RNZ A;  2F3G A;  3IT5 A;  1GLC F;  4QPB A;  3SLU A;  1GPR A;  4QP5 A;  3CSQ A;  1GLA F;  5KVP A;  1F3G A;  3NYY A;  1GLB F;  1F3Z A;  2B0P A;  4BH5 A;  4ZYB A;  2GPR A;  1AX3 A;  5B0H A;  2MP0 B;  2B44 A;  1GLE F;  3IT7 A;  3OUR B;  1O2F A;  2GU1 A;  1QWY A;  1GLD F;  3UZ0 B;  2B13 A;  4LXC A;  2HSI A;  3TUF B; 
#chains in the Genus database with same CATH homology
 4RNY A;  4JBW M;  1GGR A;  4RNZ A;  2F3G A;  3IT5 A;  1GLC F;  4QPB A;  3SLU A;  1GPR A;  4QP5 A;  3CSQ A;  1GLA F;  5KVP A;  1F3G A;  3NYY A;  1GLB F;  1F3Z A;  2B0P A;  4BH5 A;  4ZYB A;  2GPR A;  1AX3 A;  5B0H A;  2MP0 B;  2B44 A;  1GLE F;  3IT7 A;  3OUR B;  1O2F A;  2GU1 A;  1QWY A;  1GLD F;  3UZ0 B;  2B13 A;  4LXC A;  2HSI A;  3TUF B; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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