3IT7A

Crystal structure of the lasa virulence factor from pseudomonas aeruginosa
Total Genus 48
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
48
sequence length
182
structure length
182
Chain Sequence
APPSNLMQLPWRQGYSWQPNGAHSNTGSGYPYSSFDASYDWPRWGSATYSVVAAHAGTVRVLSRCQVRVTHPSGWATNYYHMDQIQVSNGQQVSADTKLGVYAGNINTALCEGGSSTGPHLHFSLLYNGAFVSLQGASFGPYRINVGTSNYDNDCRRYYFYNQSAGTTHCAFRPLYNPGLAL
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
molecule tags Hydrolase
molecule keywords Protease lasA
publication title Crystal structure of the LasA virulence factor from Pseudomonas aeruginosa: substrate specificity and mechanism of M23 metallopeptidases.
pubmed doi rcsb
total genus 48
structure length 182
sequence length 182
chains with identical sequence B
ec nomenclature ec 3.4.24.-:
pdb deposition date 2009-08-27

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01551 Peptidase_M23 Peptidase family M23
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.70.70.10 Mainly Beta Distorted Sandwich Glucose Permease (Domain IIA) Glucose Permease (Domain IIA) 3it7A00
4BH5A 4QPBA 1GPRA 2B44A 3IT5A 1GGRA 3TUFB 4RNYA 3CSQA 1GLCF 1GLAF 2GU1A 1F3ZA 4RNZA 5KVPA 2GPRA 3SLUA 5B0HA 1QWYA 3OURB 3IT7A 4JBWM 1F3GA 2B0PA 1O2FA 4ZYBA 3NYYA 1GLDF 3UZ0B 2MP0B 1GLBF 2HSIA 2F3GA 1AX3A 4QP5A 1GLEF 2B13A 4LXCA
chains in the Genus database with same CATH superfamily
4BH5A 4QPBA 1GPRA 2B44A 3IT5A 1GGRA 3TUFB 4RNYA 3CSQA 1GLCF 1GLAF 2GU1A 1F3ZA 4RNZA 5KVPA 2GPRA 3SLUA 5B0HA 1QWYA 3OURB 3IT7A 4JBWM 1F3GA 2B0PA 1O2FA 4ZYBA 3NYYA 1GLDF 3UZ0B 2MP0B 1GLBF 2HSIA 2F3GA 1AX3A 4QP5A 1GLEF 2B13A 4LXCA
chains in the Genus database with same CATH topology
4BH5A 4QPBA 1GPRA 2B44A 3IT5A 1GGRA 3TUFB 4RNYA 3CSQA 1GLCF 1GLAF 2GU1A 1F3ZA 4RNZA 5KVPA 2GPRA 3SLUA 5B0HA 1QWYA 3OURB 3IT7A 4JBWM 1F3GA 2B0PA 1O2FA 4ZYBA 3NYYA 1GLDF 3UZ0B 2MP0B 1GLBF 2HSIA 2F3GA 1AX3A 4QP5A 1GLEF 2B13A 4LXCA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4BH5 A;  4QPB A;  1GPR A;  2B44 A;  3IT5 A;  1GGR A;  3TUF B;  4RNY A;  3CSQ A;  1GLC F;  1GLA F;  2GU1 A;  1F3Z A;  4RNZ A;  5KVP A;  2GPR A;  3SLU A;  5B0H A;  1QWY A;  3OUR B;  3IT7 A;  4JBW M;  1F3G A;  2B0P A;  1O2F A;  4ZYB A;  3NYY A;  1GLD F;  3UZ0 B;  2MP0 B;  1GLB F;  2HSI A;  2F3G A;  1AX3 A;  4QP5 A;  1GLE F;  2B13 A;  4LXC A; 
#chains in the Genus database with same CATH topology
 4BH5 A;  4QPB A;  1GPR A;  2B44 A;  3IT5 A;  1GGR A;  3TUF B;  4RNY A;  3CSQ A;  1GLC F;  1GLA F;  2GU1 A;  1F3Z A;  4RNZ A;  5KVP A;  2GPR A;  3SLU A;  5B0H A;  1QWY A;  3OUR B;  3IT7 A;  4JBW M;  1F3G A;  2B0P A;  1O2F A;  4ZYB A;  3NYY A;  1GLD F;  3UZ0 B;  2MP0 B;  1GLB F;  2HSI A;  2F3G A;  1AX3 A;  4QP5 A;  1GLE F;  2B13 A;  4LXC A; 
#chains in the Genus database with same CATH homology
 4BH5 A;  4QPB A;  1GPR A;  2B44 A;  3IT5 A;  1GGR A;  3TUF B;  4RNY A;  3CSQ A;  1GLC F;  1GLA F;  2GU1 A;  1F3Z A;  4RNZ A;  5KVP A;  2GPR A;  3SLU A;  5B0H A;  1QWY A;  3OUR B;  3IT7 A;  4JBW M;  1F3G A;  2B0P A;  1O2F A;  4ZYB A;  3NYY A;  1GLD F;  3UZ0 B;  2MP0 B;  1GLB F;  2HSI A;  2F3G A;  1AX3 A;  4QP5 A;  1GLE F;  2B13 A;  4LXC A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...