3M0DD

Crystal structure of the traf1:traf2:ciap2 complex
Total Genus 17
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
17
sequence length
75
structure length
75
Chain Sequence
MLSCELYRMSTYSTFPAGVPVSERSLARAGFYYTGVNDKVKCFCCGLMLDNWKRGDSPTEKHKKLYPSCRFVQSL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal structures of the TRAF2: cIAP2 and the TRAF1: TRAF2: cIAP2 complexes: affinity, specificity, and regulation.
pubmed doi rcsb
molecule tags Signaling protein
source organism Homo sapiens
molecule keywords TNF receptor-associated factor 2
total genus 17
structure length 75
sequence length 75
ec nomenclature ec 2.3.2.27: RING-type E3 ubiquitin transferase.
pdb deposition date 2010-03-02

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
D PF00653 BIR Inhibitor of Apoptosis domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.1170.10 Mainly Alpha Orthogonal Bundle Inhibitor Of Apoptosis Protein (2mihbC-IAP-1); Chain A Inhibitor Of Apoptosis Protein (2mihbC-IAP-1); Chain A 3m0dD00
3F7HA 4WVTA 3G76A 3UIGA 1SE0A 3UIHA 3UEHA 1OXNA 3GT9A 4EB9A 4KJVA 3SIPE 3UIJA 3EYLA 3UW5A 1I3OE 4MU7A 1C9QA 1JD5A 5C84A 2I3IA 1TW6A 1JD6A 1XOXA 1TFTA 1XB1A 3OZ1A 2I3HA 4J44A 3MUPA 2VSLA 3CLXA 4HY5A 3UEEA 3M0DD 4MTIA 2RAWA 3CM2A 3GTAA 4J47A 2VM5A 3CM7A 3UECA 3UIIA 3UEDA 3M1DA 3M0AD 2QFAA 2OPYA 3D9TA 1OXQA 5C0LA 4KMPA 5C3KA 3F7IA 1G73C 2OPZA 3UEGA 5C7CA 1SDZA 4KJUA 1TFQA 2POPB 4J45A 2UVLA 1XB0A 3UW4A 3D9UA 4LGEA 3UIKA 1G3FA 3UEIA 5C0KA 4LGUA 5C83A 3UEFA 4J48A 5C7AA 1M4MA 4WVSA 4KMNA 1JD4A 4OXCA 2POIA 3F7GA 4EC4A 4HY0A 3SIQA 4HY4A 4J3YA 1F3HA 1QBHA 4A0IA 4A0JA 5C3HA 3HL5A 5C7DA 2RAXA 1Q4QA 1F9XA 3T6PA 1OY7A 5C7BA 4A0NA 4WVUA 2QRAA 4MTZA 2JK7A 4J46A 1E31A 1NW9A
chains in the Genus database with same CATH superfamily
3F7HA 4WVTA 3G76A 3UIGA 1SE0A 3UIHA 3UEHA 1OXNA 3GT9A 4EB9A 4KJVA 3SIPE 3UIJA 3EYLA 3UW5A 1I3OE 4MU7A 1C9QA 1JD5A 5C84A 2I3IA 1TW6A 1JD6A 1XOXA 1TFTA 1XB1A 3OZ1A 2I3HA 4J44A 3MUPA 2VSLA 3CLXA 4HY5A 3UEEA 3M0DD 4MTIA 2RAWA 3CM2A 3GTAA 4J47A 2VM5A 3CM7A 3UECA 3UIIA 3UEDA 3M1DA 3M0AD 2QFAA 2OPYA 3D9TA 1OXQA 5C0LA 4KMPA 5C3KA 3F7IA 1G73C 2OPZA 3UEGA 5C7CA 1SDZA 4KJUA 1TFQA 2POPB 4J45A 2UVLA 1XB0A 3UW4A 3D9UA 4LGEA 3UIKA 1G3FA 3UEIA 5C0KA 4LGUA 5C83A 3UEFA 4J48A 5C7AA 1M4MA 4WVSA 4KMNA 1JD4A 4OXCA 2POIA 3F7GA 4EC4A 4HY0A 3SIQA 4HY4A 4J3YA 1F3HA 1QBHA 4A0IA 4A0JA 5C3HA 3HL5A 5C7DA 2RAXA 1Q4QA 1F9XA 3T6PA 1OY7A 5C7BA 4A0NA 4WVUA 2QRAA 4MTZA 2JK7A 4J46A 1E31A 1NW9A
chains in the Genus database with same CATH topology
3F7HA 4WVTA 3G76A 3UIGA 1SE0A 3UIHA 3UEHA 1OXNA 3GT9A 4EB9A 4KJVA 3SIPE 3UIJA 3EYLA 3UW5A 1I3OE 4MU7A 1C9QA 1JD5A 5C84A 2I3IA 1TW6A 1JD6A 1XOXA 1TFTA 1XB1A 3OZ1A 2I3HA 4J44A 3MUPA 2VSLA 3CLXA 4HY5A 3UEEA 3M0DD 4MTIA 2RAWA 3CM2A 3GTAA 4J47A 2VM5A 3CM7A 3UECA 3UIIA 3UEDA 3M1DA 3M0AD 2QFAA 2OPYA 3D9TA 1OXQA 5C0LA 4KMPA 5C3KA 3F7IA 1G73C 2OPZA 3UEGA 5C7CA 1SDZA 4KJUA 1TFQA 2POPB 4J45A 2UVLA 1XB0A 3UW4A 3D9UA 4LGEA 3UIKA 1G3FA 3UEIA 5C0KA 4LGUA 5C83A 3UEFA 4J48A 5C7AA 1M4MA 4WVSA 4KMNA 1JD4A 4OXCA 2POIA 3F7GA 4EC4A 4HY0A 3SIQA 4HY4A 4J3YA 1F3HA 1QBHA 4A0IA 4A0JA 5C3HA 3HL5A 5C7DA 2RAXA 1Q4QA 1F9XA 3T6PA 1OY7A 5C7BA 4A0NA 4WVUA 2QRAA 4MTZA 2JK7A 4J46A 1E31A 1NW9A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3F7H A;  4WVT A;  3G76 A;  3UIG A;  1SE0 A;  3UIH A;  3UEH A;  1OXN A;  3GT9 A;  4EB9 A;  4KJV A;  3SIP E;  3UIJ A;  3EYL A;  3UW5 A;  1I3O E;  4MU7 A;  1C9Q A;  1JD5 A;  5C84 A;  2I3I A;  1TW6 A;  1JD6 A;  1XOX A;  1TFT A;  1XB1 A;  3OZ1 A;  2I3H A;  4J44 A;  3MUP A;  2VSL A;  3CLX A;  4HY5 A;  3UEE A;  3M0D D;  4MTI A;  2RAW A;  3CM2 A;  3GTA A;  4J47 A;  2VM5 A;  3CM7 A;  3UEC A;  3UII A;  3UED A;  3M1D A;  3M0A D;  2QFA A;  2OPY A;  3D9T A;  1OXQ A;  5C0L A;  4KMP A;  5C3K A;  3F7I A;  1G73 C;  2OPZ A;  3UEG A;  5C7C A;  1SDZ A;  4KJU A;  1TFQ A;  2POP B;  4J45 A;  2UVL A;  1XB0 A;  3UW4 A;  3D9U A;  4LGE A;  3UIK A;  1G3F A;  3UEI A;  5C0K A;  4LGU A;  5C83 A;  3UEF A;  4J48 A;  5C7A A;  1M4M A;  4WVS A;  4KMN A;  1JD4 A;  4OXC A;  2POI A;  3F7G A;  4EC4 A;  4HY0 A;  3SIQ A;  4HY4 A;  4J3Y A;  1F3H A;  1QBH A;  4A0I A;  4A0J A;  5C3H A;  3HL5 A;  5C7D A;  2RAX A;  1Q4Q A;  1F9X A;  3T6P A;  1OY7 A;  5C7B A;  4A0N A;  4WVU A;  2QRA A;  4MTZ A;  2JK7 A;  4J46 A;  1E31 A;  1NW9 A; 
#chains in the Genus database with same CATH topology
 3F7H A;  4WVT A;  3G76 A;  3UIG A;  1SE0 A;  3UIH A;  3UEH A;  1OXN A;  3GT9 A;  4EB9 A;  4KJV A;  3SIP E;  3UIJ A;  3EYL A;  3UW5 A;  1I3O E;  4MU7 A;  1C9Q A;  1JD5 A;  5C84 A;  2I3I A;  1TW6 A;  1JD6 A;  1XOX A;  1TFT A;  1XB1 A;  3OZ1 A;  2I3H A;  4J44 A;  3MUP A;  2VSL A;  3CLX A;  4HY5 A;  3UEE A;  3M0D D;  4MTI A;  2RAW A;  3CM2 A;  3GTA A;  4J47 A;  2VM5 A;  3CM7 A;  3UEC A;  3UII A;  3UED A;  3M1D A;  3M0A D;  2QFA A;  2OPY A;  3D9T A;  1OXQ A;  5C0L A;  4KMP A;  5C3K A;  3F7I A;  1G73 C;  2OPZ A;  3UEG A;  5C7C A;  1SDZ A;  4KJU A;  1TFQ A;  2POP B;  4J45 A;  2UVL A;  1XB0 A;  3UW4 A;  3D9U A;  4LGE A;  3UIK A;  1G3F A;  3UEI A;  5C0K A;  4LGU A;  5C83 A;  3UEF A;  4J48 A;  5C7A A;  1M4M A;  4WVS A;  4KMN A;  1JD4 A;  4OXC A;  2POI A;  3F7G A;  4EC4 A;  4HY0 A;  3SIQ A;  4HY4 A;  4J3Y A;  1F3H A;  1QBH A;  4A0I A;  4A0J A;  5C3H A;  3HL5 A;  5C7D A;  2RAX A;  1Q4Q A;  1F9X A;  3T6P A;  1OY7 A;  5C7B A;  4A0N A;  4WVU A;  2QRA A;  4MTZ A;  2JK7 A;  4J46 A;  1E31 A;  1NW9 A; 
#chains in the Genus database with same CATH homology
 3F7H A;  4WVT A;  3G76 A;  3UIG A;  1SE0 A;  3UIH A;  3UEH A;  1OXN A;  3GT9 A;  4EB9 A;  4KJV A;  3SIP E;  3UIJ A;  3EYL A;  3UW5 A;  1I3O E;  4MU7 A;  1C9Q A;  1JD5 A;  5C84 A;  2I3I A;  1TW6 A;  1JD6 A;  1XOX A;  1TFT A;  1XB1 A;  3OZ1 A;  2I3H A;  4J44 A;  3MUP A;  2VSL A;  3CLX A;  4HY5 A;  3UEE A;  3M0D D;  4MTI A;  2RAW A;  3CM2 A;  3GTA A;  4J47 A;  2VM5 A;  3CM7 A;  3UEC A;  3UII A;  3UED A;  3M1D A;  3M0A D;  2QFA A;  2OPY A;  3D9T A;  1OXQ A;  5C0L A;  4KMP A;  5C3K A;  3F7I A;  1G73 C;  2OPZ A;  3UEG A;  5C7C A;  1SDZ A;  4KJU A;  1TFQ A;  2POP B;  4J45 A;  2UVL A;  1XB0 A;  3UW4 A;  3D9U A;  4LGE A;  3UIK A;  1G3F A;  3UEI A;  5C0K A;  4LGU A;  5C83 A;  3UEF A;  4J48 A;  5C7A A;  1M4M A;  4WVS A;  4KMN A;  1JD4 A;  4OXC A;  2POI A;  3F7G A;  4EC4 A;  4HY0 A;  3SIQ A;  4HY4 A;  4J3Y A;  1F3H A;  1QBH A;  4A0I A;  4A0J A;  5C3H A;  3HL5 A;  5C7D A;  2RAX A;  1Q4Q A;  1F9X A;  3T6P A;  1OY7 A;  5C7B A;  4A0N A;  4WVU A;  2QRA A;  4MTZ A;  2JK7 A;  4J46 A;  1E31 A;  1NW9 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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