3VYQA

Crystal structure of the methyl cpg binding domain of mbd4 in complex with the 5mcg/tg sequence in space group p1
Total Genus 12
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
12
sequence length
63
structure length
63
Chain Sequence
HKPVPCGWERVVKQRLSGKTAGKFDVYFISPQGLKFRSKRSLANYLLKNGETFLKPEDFNFTV
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

molecule tags Hydrolase/dna
molecule keywords Methyl-CpG-binding domain protein 4
publication title Structural basis of the versatile DNA recognition ability of the methyl-CpG binding domain of methyl-CpG binding domain protein 4
pubmed doi rcsb
source organism Mus musculus
total genus 12
structure length 63
sequence length 63
chains with identical sequence D
ec nomenclature ec 3.2.2.-:
pdb deposition date 2012-10-02

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01429 MBD Methyl-CpG binding domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.890.10 Alpha Beta 2-Layer Sandwich Methyl-cpg-binding Protein 2; Chain A Methyl-cpg-binding Protein 2; Chain A 3vyqA00
3C2IA 2MOEA 3VXXA 3VYBA 3VYQA 1IG4A 3VXVA 1UB1A 1D9NA 1QK9A 2MB7A 5BT2A 2KY8A 4LG7A
chains in the Genus database with same CATH superfamily
3C2IA 2MOEA 3VXXA 3VYBA 3VYQA 1IG4A 3VXVA 1UB1A 1D9NA 1QK9A 2MB7A 5BT2A 2KY8A 4LG7A
chains in the Genus database with same CATH topology
3C2IA 2MOEA 3VXXA 3VYBA 3VYQA 1IG4A 3VXVA 1UB1A 1D9NA 1QK9A 2MB7A 5BT2A 2KY8A 4LG7A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3C2I A;  2MOE A;  3VXX A;  3VYB A;  3VYQ A;  1IG4 A;  3VXV A;  1UB1 A;  1D9N A;  1QK9 A;  2MB7 A;  5BT2 A;  2KY8 A;  4LG7 A; 
#chains in the Genus database with same CATH topology
 3C2I A;  2MOE A;  3VXX A;  3VYB A;  3VYQ A;  1IG4 A;  3VXV A;  1UB1 A;  1D9N A;  1QK9 A;  2MB7 A;  5BT2 A;  2KY8 A;  4LG7 A; 
#chains in the Genus database with same CATH homology
 3C2I A;  2MOE A;  3VXX A;  3VYB A;  3VYQ A;  1IG4 A;  3VXV A;  1UB1 A;  1D9N A;  1QK9 A;  2MB7 A;  5BT2 A;  2KY8 A;  4LG7 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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