3WDDA

Mutant n-terminal domain of mycobacterium tuberculosis clpc1, f2y, bound to cyclomarin a
Total Genus 59
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
59
sequence length
147
structure length
147
Chain Sequence
MYERFTDRARRVVVLAQEEARMLNHNYIGTEHILLGLIHEGEGVAAKSLESLGISLEGVRSQVEEIIGQGQQAPSGHIPFTPRAKKVLELSLREALQLGHNYIGTEHILLGLIREGEGVAAQVLVKLGAELTRVRQQVIQLLSGYLE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural basis of mycobacterial inhibition by cyclomarin A
pubmed doi rcsb
molecule keywords Probable ATP-dependent Clp protease ATP-binding subunit
molecule tags Chaperone/antimicrobial protein
source organism Mycobacterium tuberculosis
total genus 59
structure length 147
sequence length 147
ec nomenclature
pdb deposition date 2013-06-14

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF02861 Clp_N Clp amino terminal domain, pathogenicity island component
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.1780.10 Mainly Alpha Orthogonal Bundle Double Clp-N motif Clp, N-terminal domain 3wddA00
1R6OA 3ZRIA 4P15A 2K77A 5HBNA 1KHYA 1R6CX 4Y0BA 2Y1RA 1MG9B 3WDDA 4UQWA 3FH2A 2Y1QA 1K6KA 1QVRA 4IRFA 1R6QA 3WDEA 1KSFX 1LZWB 1MBXA 5GUIA 3PXGA 3ZRJA 3WDBA 4HH5A 1MBVA 1R6BX 1MBUA 4IODA 3FESA 4Y0CA 3WDCA 4HH6A
chains in the Genus database with same CATH superfamily
1R6OA 3ZRIA 4P15A 2K77A 5HBNA 1KHYA 1R6CX 4Y0BA 2Y1RA 1MG9B 3WDDA 4UQWA 3FH2A 2Y1QA 1K6KA 1QVRA 4IRFA 1R6QA 3WDEA 1KSFX 1LZWB 1MBXA 5GUIA 3PXGA 3ZRJA 3WDBA 4HH5A 1MBVA 1R6BX 1MBUA 4IODA 3FESA 4Y0CA 3WDCA 4HH6A
chains in the Genus database with same CATH topology
1R6OA 3ZRIA 4P15A 2K77A 5HBNA 1KHYA 1R6CX 4Y0BA 2Y1RA 1MG9B 3WDDA 4UQWA 3FH2A 2Y1QA 1K6KA 1QVRA 4IRFA 1R6QA 3WDEA 1KSFX 1LZWB 1MBXA 5GUIA 3PXGA 3ZRJA 3WDBA 4HH5A 1MBVA 1R6BX 1MBUA 4IODA 3FESA 4Y0CA 3WDCA 4HH6A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1R6O A;  3ZRI A;  4P15 A;  2K77 A;  5HBN A;  1KHY A;  1R6C X;  4Y0B A;  2Y1R A;  1MG9 B;  3WDD A;  4UQW A;  3FH2 A;  2Y1Q A;  1K6K A;  1QVR A;  4IRF A;  1R6Q A;  3WDE A;  1KSF X;  1LZW B;  1MBX A;  5GUI A;  3PXG A;  3ZRJ A;  3WDB A;  4HH5 A;  1MBV A;  1R6B X;  1MBU A;  4IOD A;  3FES A;  4Y0C A;  3WDC A;  4HH6 A; 
#chains in the Genus database with same CATH topology
 1R6O A;  3ZRI A;  4P15 A;  2K77 A;  5HBN A;  1KHY A;  1R6C X;  4Y0B A;  2Y1R A;  1MG9 B;  3WDD A;  4UQW A;  3FH2 A;  2Y1Q A;  1K6K A;  1QVR A;  4IRF A;  1R6Q A;  3WDE A;  1KSF X;  1LZW B;  1MBX A;  5GUI A;  3PXG A;  3ZRJ A;  3WDB A;  4HH5 A;  1MBV A;  1R6B X;  1MBU A;  4IOD A;  3FES A;  4Y0C A;  3WDC A;  4HH6 A; 
#chains in the Genus database with same CATH homology
 1R6O A;  3ZRI A;  4P15 A;  2K77 A;  5HBN A;  1KHY A;  1R6C X;  4Y0B A;  2Y1R A;  1MG9 B;  3WDD A;  4UQW A;  3FH2 A;  2Y1Q A;  1K6K A;  1QVR A;  4IRF A;  1R6Q A;  3WDE A;  1KSF X;  1LZW B;  1MBX A;  5GUI A;  3PXG A;  3ZRJ A;  3WDB A;  4HH5 A;  1MBV A;  1R6B X;  1MBU A;  4IOD A;  3FES A;  4Y0C A;  3WDC A;  4HH6 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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#similar chains, but unknotted
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