3WDEA

Mutant n-terminal domain of mycobacterium tuberculosis clpc1, f80y, bound to cyclomarin a
Total Genus 60
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
60
sequence length
147
structure length
147
Chain Sequence
MFERFTDRARRVVVLAQEEARMLNHNYIGTEHILLGLIHEGEGVAAKSLESLGISLEGVRSQVEEIIGQGQQAPSGHIPYTPRAKKVLELSLREALQLGHNYIGTEHILLGLIREGEGVAAQVLVKLGAELTRVRQQVIQLLSGYLE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural basis of mycobacterial inhibition by cyclomarin A
pubmed doi rcsb
molecule tags Chaperone/antimicrobial protein
source organism Mycobacterium tuberculosis
molecule keywords Probable ATP-dependent Clp protease ATP-binding subunit
total genus 60
structure length 147
sequence length 147
ec nomenclature
pdb deposition date 2013-06-14

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF02861 Clp_N Clp amino terminal domain, pathogenicity island component
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.1780.10 Mainly Alpha Orthogonal Bundle Double Clp-N motif Clp, N-terminal domain 3wdeA00
3ZRJA 1MBUA 5GUIA 4UQWA 1R6QA 1MBXA 1MBVA 3ZRIA 1MG9B 5HBNA 1KHYA 1LZWB 2K77A 3FH2A 1R6OA 3WDCA 3WDDA 4HH5A 4Y0BA 1R6CX 3WDEA 4IRFA 3PXGA 1R6BX 2Y1QA 4P15A 1K6KA 3WDBA 2Y1RA 4IODA 4Y0CA 1KSFX 4HH6A 3FESA 1QVRA
chains in the Genus database with same CATH superfamily
3ZRJA 1MBUA 5GUIA 4UQWA 1R6QA 1MBXA 1MBVA 3ZRIA 1MG9B 5HBNA 1KHYA 1LZWB 2K77A 3FH2A 1R6OA 3WDCA 3WDDA 4HH5A 4Y0BA 1R6CX 3WDEA 4IRFA 3PXGA 1R6BX 2Y1QA 4P15A 1K6KA 3WDBA 2Y1RA 4IODA 4Y0CA 1KSFX 4HH6A 3FESA 1QVRA
chains in the Genus database with same CATH topology
3ZRJA 1MBUA 5GUIA 4UQWA 1R6QA 1MBXA 1MBVA 3ZRIA 1MG9B 5HBNA 1KHYA 1LZWB 2K77A 3FH2A 1R6OA 3WDCA 3WDDA 4HH5A 4Y0BA 1R6CX 3WDEA 4IRFA 3PXGA 1R6BX 2Y1QA 4P15A 1K6KA 3WDBA 2Y1RA 4IODA 4Y0CA 1KSFX 4HH6A 3FESA 1QVRA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3ZRJ A;  1MBU A;  5GUI A;  4UQW A;  1R6Q A;  1MBX A;  1MBV A;  3ZRI A;  1MG9 B;  5HBN A;  1KHY A;  1LZW B;  2K77 A;  3FH2 A;  1R6O A;  3WDC A;  3WDD A;  4HH5 A;  4Y0B A;  1R6C X;  3WDE A;  4IRF A;  3PXG A;  1R6B X;  2Y1Q A;  4P15 A;  1K6K A;  3WDB A;  2Y1R A;  4IOD A;  4Y0C A;  1KSF X;  4HH6 A;  3FES A;  1QVR A; 
#chains in the Genus database with same CATH topology
 3ZRJ A;  1MBU A;  5GUI A;  4UQW A;  1R6Q A;  1MBX A;  1MBV A;  3ZRI A;  1MG9 B;  5HBN A;  1KHY A;  1LZW B;  2K77 A;  3FH2 A;  1R6O A;  3WDC A;  3WDD A;  4HH5 A;  4Y0B A;  1R6C X;  3WDE A;  4IRF A;  3PXG A;  1R6B X;  2Y1Q A;  4P15 A;  1K6K A;  3WDB A;  2Y1R A;  4IOD A;  4Y0C A;  1KSF X;  4HH6 A;  3FES A;  1QVR A; 
#chains in the Genus database with same CATH homology
 3ZRJ A;  1MBU A;  5GUI A;  4UQW A;  1R6Q A;  1MBX A;  1MBV A;  3ZRI A;  1MG9 B;  5HBN A;  1KHY A;  1LZW B;  2K77 A;  3FH2 A;  1R6O A;  3WDC A;  3WDD A;  4HH5 A;  4Y0B A;  1R6C X;  3WDE A;  4IRF A;  3PXG A;  1R6B X;  2Y1Q A;  4P15 A;  1K6K A;  3WDB A;  2Y1R A;  4IOD A;  4Y0C A;  1KSF X;  4HH6 A;  3FES A;  1QVR A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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