3WDEA

Mutant n-terminal domain of mycobacterium tuberculosis clpc1, f80y, bound to cyclomarin a
Total Genus 60
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
60
sequence length
147
structure length
147
Chain Sequence
MFERFTDRARRVVVLAQEEARMLNHNYIGTEHILLGLIHEGEGVAAKSLESLGISLEGVRSQVEEIIGQGQQAPSGHIPYTPRAKKVLELSLREALQLGHNYIGTEHILLGLIREGEGVAAQVLVKLGAELTRVRQQVIQLLSGYLE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural basis of mycobacterial inhibition by cyclomarin A
pubmed doi rcsb
molecule keywords Probable ATP-dependent Clp protease ATP-binding subunit
molecule tags Chaperone/antimicrobial protein
source organism Mycobacterium tuberculosis
total genus 60
structure length 147
sequence length 147
ec nomenclature
pdb deposition date 2013-06-14

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF02861 Clp_N Clp amino terminal domain, pathogenicity island component
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.1780.10 Mainly Alpha Orthogonal Bundle Double Clp-N motif Clp, N-terminal domain 3wdeA00
4Y0BA 3WDCA 3FESA 2K77A 3WDEA 1MG9B 1R6QA 3WDBA 1R6CX 4UQWA 3ZRIA 4Y0CA 1KSFX 1MBXA 1QVRA 5HBNA 5GUIA 4HH5A 2Y1RA 4P15A 1R6BX 3ZRJA 1K6KA 3WDDA 1R6OA 1MBUA 1LZWB 2Y1QA 1MBVA 3PXGA 4IODA 4HH6A 4IRFA 1KHYA 3FH2A
chains in the Genus database with same CATH superfamily
4Y0BA 3WDCA 3FESA 2K77A 3WDEA 1MG9B 1R6QA 3WDBA 1R6CX 4UQWA 3ZRIA 4Y0CA 1KSFX 1MBXA 1QVRA 5HBNA 5GUIA 4HH5A 2Y1RA 4P15A 1R6BX 3ZRJA 1K6KA 3WDDA 1R6OA 1MBUA 1LZWB 2Y1QA 1MBVA 3PXGA 4IODA 4HH6A 4IRFA 1KHYA 3FH2A
chains in the Genus database with same CATH topology
4Y0BA 3WDCA 3FESA 2K77A 3WDEA 1MG9B 1R6QA 3WDBA 1R6CX 4UQWA 3ZRIA 4Y0CA 1KSFX 1MBXA 1QVRA 5HBNA 5GUIA 4HH5A 2Y1RA 4P15A 1R6BX 3ZRJA 1K6KA 3WDDA 1R6OA 1MBUA 1LZWB 2Y1QA 1MBVA 3PXGA 4IODA 4HH6A 4IRFA 1KHYA 3FH2A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4Y0B A;  3WDC A;  3FES A;  2K77 A;  3WDE A;  1MG9 B;  1R6Q A;  3WDB A;  1R6C X;  4UQW A;  3ZRI A;  4Y0C A;  1KSF X;  1MBX A;  1QVR A;  5HBN A;  5GUI A;  4HH5 A;  2Y1R A;  4P15 A;  1R6B X;  3ZRJ A;  1K6K A;  3WDD A;  1R6O A;  1MBU A;  1LZW B;  2Y1Q A;  1MBV A;  3PXG A;  4IOD A;  4HH6 A;  4IRF A;  1KHY A;  3FH2 A; 
#chains in the Genus database with same CATH topology
 4Y0B A;  3WDC A;  3FES A;  2K77 A;  3WDE A;  1MG9 B;  1R6Q A;  3WDB A;  1R6C X;  4UQW A;  3ZRI A;  4Y0C A;  1KSF X;  1MBX A;  1QVR A;  5HBN A;  5GUI A;  4HH5 A;  2Y1R A;  4P15 A;  1R6B X;  3ZRJ A;  1K6K A;  3WDD A;  1R6O A;  1MBU A;  1LZW B;  2Y1Q A;  1MBV A;  3PXG A;  4IOD A;  4HH6 A;  4IRF A;  1KHY A;  3FH2 A; 
#chains in the Genus database with same CATH homology
 4Y0B A;  3WDC A;  3FES A;  2K77 A;  3WDE A;  1MG9 B;  1R6Q A;  3WDB A;  1R6C X;  4UQW A;  3ZRI A;  4Y0C A;  1KSF X;  1MBX A;  1QVR A;  5HBN A;  5GUI A;  4HH5 A;  2Y1R A;  4P15 A;  1R6B X;  3ZRJ A;  1K6K A;  3WDD A;  1R6O A;  1MBU A;  1LZW B;  2Y1Q A;  1MBV A;  3PXG A;  4IOD A;  4HH6 A;  4IRF A;  1KHY A;  3FH2 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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#similar chains, but unknotted
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