3G76A

Crystal structure of xiap-bir3 in complex with a bivalent compound
Total Genus 22
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
22
sequence length
97
structure length
97
Chain Sequence
NSTNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Structural basis for bivalent smac-mimetics recognition in the IAP protein family
pubmed doi rcsb
molecule tags Ligase
source organism Homo sapiens
molecule keywords Baculoviral IAP repeat-containing protein 4
total genus 22
structure length 97
sequence length 97
chains with identical sequence B, C, D, E, F, G, H
ec nomenclature ec 2.3.2.27: RING-type E3 ubiquitin transferase.
pdb deposition date 2009-02-09

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00653 BIR Inhibitor of Apoptosis domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.1170.10 Mainly Alpha Orthogonal Bundle Inhibitor Of Apoptosis Protein (2mihbC-IAP-1); Chain A Inhibitor Of Apoptosis Protein (2mihbC-IAP-1); Chain A 3g76A00
5C84A 1SDZA 3GTAA 4OXCA 1XOXA 5C7AA 1Q4QA 3HL5A 2RAXA 4J46A 3D9UA 5C3KA 3F7HA 4LGUA 1OY7A 1G3FA 4WVSA 1TFQA 4WVTA 4EB9A 3UIIA 3UIJA 5C0LA 4HY5A 3F7IA 4MTIA 3UECA 3MUPA 1G73C 5C7CA 2JK7A 3EYLA 1QBHA 1F9XA 4MU7A 1I3OE 3UIKA 4J44A 3SIPE 3CM2A 2RAWA 5C3HA 2POIA 1SE0A 3OZ1A 4J48A 3M0DD 4A0IA 3UW5A 3G76A 3M0AD 4WVUA 3T6PA 4KMPA 4HY0A 3UW4A 1JD5A 1TFTA 3UEDA 3UEHA 4A0NA 1JD6A 5C7BA 4HY4A 3UEFA 4KJVA 4EC4A 3D9TA 5C7DA 1XB0A 4LGEA 5C0KA 1M4MA 1JD4A 2VSLA 1OXQA 2QFAA 3UEEA 4MTZA 1C9QA 3F7GA 3SIQA 2POPB 4KMNA 4KJUA 1TW6A 1F3HA 2OPYA 3UEIA 3CLXA 1XB1A 2UVLA 3UIHA 2I3HA 2VM5A 3UIGA 4A0JA 1OXNA 1E31A 2QRAA 4J45A 3GT9A 2I3IA 4J3YA 3M1DA 3UEGA 2OPZA 1NW9A 3CM7A 4J47A 5C83A
chains in the Genus database with same CATH superfamily
5C84A 1SDZA 3GTAA 4OXCA 1XOXA 5C7AA 1Q4QA 3HL5A 2RAXA 4J46A 3D9UA 5C3KA 3F7HA 4LGUA 1OY7A 1G3FA 4WVSA 1TFQA 4WVTA 4EB9A 3UIIA 3UIJA 5C0LA 4HY5A 3F7IA 4MTIA 3UECA 3MUPA 1G73C 5C7CA 2JK7A 3EYLA 1QBHA 1F9XA 4MU7A 1I3OE 3UIKA 4J44A 3SIPE 3CM2A 2RAWA 5C3HA 2POIA 1SE0A 3OZ1A 4J48A 3M0DD 4A0IA 3UW5A 3G76A 3M0AD 4WVUA 3T6PA 4KMPA 4HY0A 3UW4A 1JD5A 1TFTA 3UEDA 3UEHA 4A0NA 1JD6A 5C7BA 4HY4A 3UEFA 4KJVA 4EC4A 3D9TA 5C7DA 1XB0A 4LGEA 5C0KA 1M4MA 1JD4A 2VSLA 1OXQA 2QFAA 3UEEA 4MTZA 1C9QA 3F7GA 3SIQA 2POPB 4KMNA 4KJUA 1TW6A 1F3HA 2OPYA 3UEIA 3CLXA 1XB1A 2UVLA 3UIHA 2I3HA 2VM5A 3UIGA 4A0JA 1OXNA 1E31A 2QRAA 4J45A 3GT9A 2I3IA 4J3YA 3M1DA 3UEGA 2OPZA 1NW9A 3CM7A 4J47A 5C83A
chains in the Genus database with same CATH topology
5C84A 1SDZA 3GTAA 4OXCA 1XOXA 5C7AA 1Q4QA 3HL5A 2RAXA 4J46A 3D9UA 5C3KA 3F7HA 4LGUA 1OY7A 1G3FA 4WVSA 1TFQA 4WVTA 4EB9A 3UIIA 3UIJA 5C0LA 4HY5A 3F7IA 4MTIA 3UECA 3MUPA 1G73C 5C7CA 2JK7A 3EYLA 1QBHA 1F9XA 4MU7A 1I3OE 3UIKA 4J44A 3SIPE 3CM2A 2RAWA 5C3HA 2POIA 1SE0A 3OZ1A 4J48A 3M0DD 4A0IA 3UW5A 3G76A 3M0AD 4WVUA 3T6PA 4KMPA 4HY0A 3UW4A 1JD5A 1TFTA 3UEDA 3UEHA 4A0NA 1JD6A 5C7BA 4HY4A 3UEFA 4KJVA 4EC4A 3D9TA 5C7DA 1XB0A 4LGEA 5C0KA 1M4MA 1JD4A 2VSLA 1OXQA 2QFAA 3UEEA 4MTZA 1C9QA 3F7GA 3SIQA 2POPB 4KMNA 4KJUA 1TW6A 1F3HA 2OPYA 3UEIA 3CLXA 1XB1A 2UVLA 3UIHA 2I3HA 2VM5A 3UIGA 4A0JA 1OXNA 1E31A 2QRAA 4J45A 3GT9A 2I3IA 4J3YA 3M1DA 3UEGA 2OPZA 1NW9A 3CM7A 4J47A 5C83A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5C84 A;  1SDZ A;  3GTA A;  4OXC A;  1XOX A;  5C7A A;  1Q4Q A;  3HL5 A;  2RAX A;  4J46 A;  3D9U A;  5C3K A;  3F7H A;  4LGU A;  1OY7 A;  1G3F A;  4WVS A;  1TFQ A;  4WVT A;  4EB9 A;  3UII A;  3UIJ A;  5C0L A;  4HY5 A;  3F7I A;  4MTI A;  3UEC A;  3MUP A;  1G73 C;  5C7C A;  2JK7 A;  3EYL A;  1QBH A;  1F9X A;  4MU7 A;  1I3O E;  3UIK A;  4J44 A;  3SIP E;  3CM2 A;  2RAW A;  5C3H A;  2POI A;  1SE0 A;  3OZ1 A;  4J48 A;  3M0D D;  4A0I A;  3UW5 A;  3G76 A;  3M0A D;  4WVU A;  3T6P A;  4KMP A;  4HY0 A;  3UW4 A;  1JD5 A;  1TFT A;  3UED A;  3UEH A;  4A0N A;  1JD6 A;  5C7B A;  4HY4 A;  3UEF A;  4KJV A;  4EC4 A;  3D9T A;  5C7D A;  1XB0 A;  4LGE A;  5C0K A;  1M4M A;  1JD4 A;  2VSL A;  1OXQ A;  2QFA A;  3UEE A;  4MTZ A;  1C9Q A;  3F7G A;  3SIQ A;  2POP B;  4KMN A;  4KJU A;  1TW6 A;  1F3H A;  2OPY A;  3UEI A;  3CLX A;  1XB1 A;  2UVL A;  3UIH A;  2I3H A;  2VM5 A;  3UIG A;  4A0J A;  1OXN A;  1E31 A;  2QRA A;  4J45 A;  3GT9 A;  2I3I A;  4J3Y A;  3M1D A;  3UEG A;  2OPZ A;  1NW9 A;  3CM7 A;  4J47 A;  5C83 A; 
#chains in the Genus database with same CATH topology
 5C84 A;  1SDZ A;  3GTA A;  4OXC A;  1XOX A;  5C7A A;  1Q4Q A;  3HL5 A;  2RAX A;  4J46 A;  3D9U A;  5C3K A;  3F7H A;  4LGU A;  1OY7 A;  1G3F A;  4WVS A;  1TFQ A;  4WVT A;  4EB9 A;  3UII A;  3UIJ A;  5C0L A;  4HY5 A;  3F7I A;  4MTI A;  3UEC A;  3MUP A;  1G73 C;  5C7C A;  2JK7 A;  3EYL A;  1QBH A;  1F9X A;  4MU7 A;  1I3O E;  3UIK A;  4J44 A;  3SIP E;  3CM2 A;  2RAW A;  5C3H A;  2POI A;  1SE0 A;  3OZ1 A;  4J48 A;  3M0D D;  4A0I A;  3UW5 A;  3G76 A;  3M0A D;  4WVU A;  3T6P A;  4KMP A;  4HY0 A;  3UW4 A;  1JD5 A;  1TFT A;  3UED A;  3UEH A;  4A0N A;  1JD6 A;  5C7B A;  4HY4 A;  3UEF A;  4KJV A;  4EC4 A;  3D9T A;  5C7D A;  1XB0 A;  4LGE A;  5C0K A;  1M4M A;  1JD4 A;  2VSL A;  1OXQ A;  2QFA A;  3UEE A;  4MTZ A;  1C9Q A;  3F7G A;  3SIQ A;  2POP B;  4KMN A;  4KJU A;  1TW6 A;  1F3H A;  2OPY A;  3UEI A;  3CLX A;  1XB1 A;  2UVL A;  3UIH A;  2I3H A;  2VM5 A;  3UIG A;  4A0J A;  1OXN A;  1E31 A;  2QRA A;  4J45 A;  3GT9 A;  2I3I A;  4J3Y A;  3M1D A;  3UEG A;  2OPZ A;  1NW9 A;  3CM7 A;  4J47 A;  5C83 A; 
#chains in the Genus database with same CATH homology
 5C84 A;  1SDZ A;  3GTA A;  4OXC A;  1XOX A;  5C7A A;  1Q4Q A;  3HL5 A;  2RAX A;  4J46 A;  3D9U A;  5C3K A;  3F7H A;  4LGU A;  1OY7 A;  1G3F A;  4WVS A;  1TFQ A;  4WVT A;  4EB9 A;  3UII A;  3UIJ A;  5C0L A;  4HY5 A;  3F7I A;  4MTI A;  3UEC A;  3MUP A;  1G73 C;  5C7C A;  2JK7 A;  3EYL A;  1QBH A;  1F9X A;  4MU7 A;  1I3O E;  3UIK A;  4J44 A;  3SIP E;  3CM2 A;  2RAW A;  5C3H A;  2POI A;  1SE0 A;  3OZ1 A;  4J48 A;  3M0D D;  4A0I A;  3UW5 A;  3G76 A;  3M0A D;  4WVU A;  3T6P A;  4KMP A;  4HY0 A;  3UW4 A;  1JD5 A;  1TFT A;  3UED A;  3UEH A;  4A0N A;  1JD6 A;  5C7B A;  4HY4 A;  3UEF A;  4KJV A;  4EC4 A;  3D9T A;  5C7D A;  1XB0 A;  4LGE A;  5C0K A;  1M4M A;  1JD4 A;  2VSL A;  1OXQ A;  2QFA A;  3UEE A;  4MTZ A;  1C9Q A;  3F7G A;  3SIQ A;  2POP B;  4KMN A;  4KJU A;  1TW6 A;  1F3H A;  2OPY A;  3UEI A;  3CLX A;  1XB1 A;  2UVL A;  3UIH A;  2I3H A;  2VM5 A;  3UIG A;  4A0J A;  1OXN A;  1E31 A;  2QRA A;  4J45 A;  3GT9 A;  2I3I A;  4J3Y A;  3M1D A;  3UEG A;  2OPZ A;  1NW9 A;  3CM7 A;  4J47 A;  5C83 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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