3GT9A

Structure of an ml-iap/xiap chimera bound to a peptidomimetic
Total Genus 24
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
24
sequence length
90
structure length
90
Chain Sequence
GPAFPGMGSEELRLASFYDWPLTAEVPPELLAAAGFFHTGHQDKVRCFFCYGGLQSWKRGDDPWTEHAKWFPGCQFLLRSKGQEYINNIH
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Antagonists of inhibitor of apoptosis proteins based on thiazole amide isosteres.
pubmed doi rcsb
molecule tags Apoptosis
source organism Homo sapiens
molecule keywords Baculoviral IAP repeat-containing 7
total genus 24
structure length 90
sequence length 90
chains with identical sequence B
ec nomenclature ec 2.3.2.27: RING-type E3 ubiquitin transferase.
pdb deposition date 2009-03-27

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00653 BIR Inhibitor of Apoptosis domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.1170.10 Mainly Alpha Orthogonal Bundle Inhibitor Of Apoptosis Protein (2mihbC-IAP-1); Chain A Inhibitor Of Apoptosis Protein (2mihbC-IAP-1); Chain A 3gt9A00
2JK7A 1XB1A 5C84A 3M1DA 4J44A 3CM2A 4WVSA 3UEDA 1NW9A 3SIQA 3M0DD 1OXNA 4LGEA 3MUPA 2QFAA 3GTAA 3UECA 1C9QA 1JD4A 4J45A 1E31A 4J3YA 2RAWA 2UVLA 3CM7A 3F7HA 5C7DA 3HL5A 5C0LA 2QRAA 3SIPE 4A0NA 3UIIA 3F7IA 5C3HA 4J48A 4EC4A 3CLXA 4J47A 4HY0A 3UIHA 4KMNA 4KJVA 5C7BA 4KJUA 4A0JA 1Q4QA 3UEHA 1M4MA 1F3HA 1TFQA 2I3IA 3UEGA 1XB0A 4WVTA 3UIGA 3UEIA 2I3HA 3GT9A 1G73C 1OXQA 4MTZA 2POIA 5C83A 5C0KA 4KMPA 5C7CA 3UIJA 3UW5A 1QBHA 4A0IA 1TW6A 3D9TA 2OPYA 4MTIA 1I3OE 2OPZA 1TFTA 1F9XA 3T6PA 2VM5A 4EB9A 4WVUA 4HY4A 1JD5A 5C7AA 3UIKA 1SDZA 2POPB 3M0AD 1OY7A 4MU7A 3UEEA 3D9UA 4LGUA 3UEFA 4OXCA 1XOXA 4HY5A 1SE0A 4J46A 5C3KA 3F7GA 1JD6A 2RAXA 2VSLA 3UW4A 3OZ1A 1G3FA 3EYLA 3G76A
chains in the Genus database with same CATH superfamily
2JK7A 1XB1A 5C84A 3M1DA 4J44A 3CM2A 4WVSA 3UEDA 1NW9A 3SIQA 3M0DD 1OXNA 4LGEA 3MUPA 2QFAA 3GTAA 3UECA 1C9QA 1JD4A 4J45A 1E31A 4J3YA 2RAWA 2UVLA 3CM7A 3F7HA 5C7DA 3HL5A 5C0LA 2QRAA 3SIPE 4A0NA 3UIIA 3F7IA 5C3HA 4J48A 4EC4A 3CLXA 4J47A 4HY0A 3UIHA 4KMNA 4KJVA 5C7BA 4KJUA 4A0JA 1Q4QA 3UEHA 1M4MA 1F3HA 1TFQA 2I3IA 3UEGA 1XB0A 4WVTA 3UIGA 3UEIA 2I3HA 3GT9A 1G73C 1OXQA 4MTZA 2POIA 5C83A 5C0KA 4KMPA 5C7CA 3UIJA 3UW5A 1QBHA 4A0IA 1TW6A 3D9TA 2OPYA 4MTIA 1I3OE 2OPZA 1TFTA 1F9XA 3T6PA 2VM5A 4EB9A 4WVUA 4HY4A 1JD5A 5C7AA 3UIKA 1SDZA 2POPB 3M0AD 1OY7A 4MU7A 3UEEA 3D9UA 4LGUA 3UEFA 4OXCA 1XOXA 4HY5A 1SE0A 4J46A 5C3KA 3F7GA 1JD6A 2RAXA 2VSLA 3UW4A 3OZ1A 1G3FA 3EYLA 3G76A
chains in the Genus database with same CATH topology
2JK7A 1XB1A 5C84A 3M1DA 4J44A 3CM2A 4WVSA 3UEDA 1NW9A 3SIQA 3M0DD 1OXNA 4LGEA 3MUPA 2QFAA 3GTAA 3UECA 1C9QA 1JD4A 4J45A 1E31A 4J3YA 2RAWA 2UVLA 3CM7A 3F7HA 5C7DA 3HL5A 5C0LA 2QRAA 3SIPE 4A0NA 3UIIA 3F7IA 5C3HA 4J48A 4EC4A 3CLXA 4J47A 4HY0A 3UIHA 4KMNA 4KJVA 5C7BA 4KJUA 4A0JA 1Q4QA 3UEHA 1M4MA 1F3HA 1TFQA 2I3IA 3UEGA 1XB0A 4WVTA 3UIGA 3UEIA 2I3HA 3GT9A 1G73C 1OXQA 4MTZA 2POIA 5C83A 5C0KA 4KMPA 5C7CA 3UIJA 3UW5A 1QBHA 4A0IA 1TW6A 3D9TA 2OPYA 4MTIA 1I3OE 2OPZA 1TFTA 1F9XA 3T6PA 2VM5A 4EB9A 4WVUA 4HY4A 1JD5A 5C7AA 3UIKA 1SDZA 2POPB 3M0AD 1OY7A 4MU7A 3UEEA 3D9UA 4LGUA 3UEFA 4OXCA 1XOXA 4HY5A 1SE0A 4J46A 5C3KA 3F7GA 1JD6A 2RAXA 2VSLA 3UW4A 3OZ1A 1G3FA 3EYLA 3G76A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2JK7 A;  1XB1 A;  5C84 A;  3M1D A;  4J44 A;  3CM2 A;  4WVS A;  3UED A;  1NW9 A;  3SIQ A;  3M0D D;  1OXN A;  4LGE A;  3MUP A;  2QFA A;  3GTA A;  3UEC A;  1C9Q A;  1JD4 A;  4J45 A;  1E31 A;  4J3Y A;  2RAW A;  2UVL A;  3CM7 A;  3F7H A;  5C7D A;  3HL5 A;  5C0L A;  2QRA A;  3SIP E;  4A0N A;  3UII A;  3F7I A;  5C3H A;  4J48 A;  4EC4 A;  3CLX A;  4J47 A;  4HY0 A;  3UIH A;  4KMN A;  4KJV A;  5C7B A;  4KJU A;  4A0J A;  1Q4Q A;  3UEH A;  1M4M A;  1F3H A;  1TFQ A;  2I3I A;  3UEG A;  1XB0 A;  4WVT A;  3UIG A;  3UEI A;  2I3H A;  3GT9 A;  1G73 C;  1OXQ A;  4MTZ A;  2POI A;  5C83 A;  5C0K A;  4KMP A;  5C7C A;  3UIJ A;  3UW5 A;  1QBH A;  4A0I A;  1TW6 A;  3D9T A;  2OPY A;  4MTI A;  1I3O E;  2OPZ A;  1TFT A;  1F9X A;  3T6P A;  2VM5 A;  4EB9 A;  4WVU A;  4HY4 A;  1JD5 A;  5C7A A;  3UIK A;  1SDZ A;  2POP B;  3M0A D;  1OY7 A;  4MU7 A;  3UEE A;  3D9U A;  4LGU A;  3UEF A;  4OXC A;  1XOX A;  4HY5 A;  1SE0 A;  4J46 A;  5C3K A;  3F7G A;  1JD6 A;  2RAX A;  2VSL A;  3UW4 A;  3OZ1 A;  1G3F A;  3EYL A;  3G76 A; 
#chains in the Genus database with same CATH topology
 2JK7 A;  1XB1 A;  5C84 A;  3M1D A;  4J44 A;  3CM2 A;  4WVS A;  3UED A;  1NW9 A;  3SIQ A;  3M0D D;  1OXN A;  4LGE A;  3MUP A;  2QFA A;  3GTA A;  3UEC A;  1C9Q A;  1JD4 A;  4J45 A;  1E31 A;  4J3Y A;  2RAW A;  2UVL A;  3CM7 A;  3F7H A;  5C7D A;  3HL5 A;  5C0L A;  2QRA A;  3SIP E;  4A0N A;  3UII A;  3F7I A;  5C3H A;  4J48 A;  4EC4 A;  3CLX A;  4J47 A;  4HY0 A;  3UIH A;  4KMN A;  4KJV A;  5C7B A;  4KJU A;  4A0J A;  1Q4Q A;  3UEH A;  1M4M A;  1F3H A;  1TFQ A;  2I3I A;  3UEG A;  1XB0 A;  4WVT A;  3UIG A;  3UEI A;  2I3H A;  3GT9 A;  1G73 C;  1OXQ A;  4MTZ A;  2POI A;  5C83 A;  5C0K A;  4KMP A;  5C7C A;  3UIJ A;  3UW5 A;  1QBH A;  4A0I A;  1TW6 A;  3D9T A;  2OPY A;  4MTI A;  1I3O E;  2OPZ A;  1TFT A;  1F9X A;  3T6P A;  2VM5 A;  4EB9 A;  4WVU A;  4HY4 A;  1JD5 A;  5C7A A;  3UIK A;  1SDZ A;  2POP B;  3M0A D;  1OY7 A;  4MU7 A;  3UEE A;  3D9U A;  4LGU A;  3UEF A;  4OXC A;  1XOX A;  4HY5 A;  1SE0 A;  4J46 A;  5C3K A;  3F7G A;  1JD6 A;  2RAX A;  2VSL A;  3UW4 A;  3OZ1 A;  1G3F A;  3EYL A;  3G76 A; 
#chains in the Genus database with same CATH homology
 2JK7 A;  1XB1 A;  5C84 A;  3M1D A;  4J44 A;  3CM2 A;  4WVS A;  3UED A;  1NW9 A;  3SIQ A;  3M0D D;  1OXN A;  4LGE A;  3MUP A;  2QFA A;  3GTA A;  3UEC A;  1C9Q A;  1JD4 A;  4J45 A;  1E31 A;  4J3Y A;  2RAW A;  2UVL A;  3CM7 A;  3F7H A;  5C7D A;  3HL5 A;  5C0L A;  2QRA A;  3SIP E;  4A0N A;  3UII A;  3F7I A;  5C3H A;  4J48 A;  4EC4 A;  3CLX A;  4J47 A;  4HY0 A;  3UIH A;  4KMN A;  4KJV A;  5C7B A;  4KJU A;  4A0J A;  1Q4Q A;  3UEH A;  1M4M A;  1F3H A;  1TFQ A;  2I3I A;  3UEG A;  1XB0 A;  4WVT A;  3UIG A;  3UEI A;  2I3H A;  3GT9 A;  1G73 C;  1OXQ A;  4MTZ A;  2POI A;  5C83 A;  5C0K A;  4KMP A;  5C7C A;  3UIJ A;  3UW5 A;  1QBH A;  4A0I A;  1TW6 A;  3D9T A;  2OPY A;  4MTI A;  1I3O E;  2OPZ A;  1TFT A;  1F9X A;  3T6P A;  2VM5 A;  4EB9 A;  4WVU A;  4HY4 A;  1JD5 A;  5C7A A;  3UIK A;  1SDZ A;  2POP B;  3M0A D;  1OY7 A;  4MU7 A;  3UEE A;  3D9U A;  4LGU A;  3UEF A;  4OXC A;  1XOX A;  4HY5 A;  1SE0 A;  4J46 A;  5C3K A;  3F7G A;  1JD6 A;  2RAX A;  2VSL A;  3UW4 A;  3OZ1 A;  1G3F A;  3EYL A;  3G76 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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