3HL5A

Crystal structure of xiap bir3 with cs3
Total Genus 27
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
27
sequence length
94
structure length
94
Chain Sequence
SHMLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTH
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Antagonism of c-IAP and XIAP proteins is required for efficient induction of cell death by small-molecule IAP antagonists.
pubmed doi rcsb
molecule tags Ligase
source organism Homo sapiens
molecule keywords Baculoviral IAP repeat-containing protein 4
total genus 27
structure length 94
sequence length 94
chains with identical sequence B
ec nomenclature ec 2.3.2.27: RING-type E3 ubiquitin transferase.
pdb deposition date 2009-05-26

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00653 BIR Inhibitor of Apoptosis domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.1170.10 Mainly Alpha Orthogonal Bundle Inhibitor Of Apoptosis Protein (2mihbC-IAP-1); Chain A Inhibitor Of Apoptosis Protein (2mihbC-IAP-1); Chain A 3hl5A00
4HY0A 3M0AD 4KMPA 4LGEA 4MTIA 3G76A 1F3HA 3F7IA 4J46A 5C84A 1XB1A 1SE0A 3GTAA 3CLXA 4EC4A 4J48A 4HY5A 3HL5A 4WVSA 1JD4A 4J44A 3UECA 3MUPA 3UEFA 2OPZA 3CM2A 5C83A 4MTZA 4KMNA 1G3FA 3UW5A 1XOXA 4A0NA 2OPYA 4WVTA 5C0LA 3UEDA 2I3IA 3UEEA 2UVLA 1OXNA 4KJUA 1OY7A 4MU7A 1QBHA 5C0KA 3F7HA 1G73C 4EB9A 5C7AA 1TFQA 4A0IA 1TFTA 3UIKA 4J3YA 3M0DD 4HY4A 1JD6A 2I3HA 1F9XA 1M4MA 2POPB 1NW9A 1TW6A 2JK7A 3SIPE 3SIQA 2VSLA 1Q4QA 2RAWA 4WVUA 3UEHA 3UIGA 1SDZA 3UW4A 4LGUA 4J45A 3UEIA 3UIHA 2VM5A 5C3HA 3CM7A 5C7BA 3M1DA 4OXCA 4A0JA 2QFAA 3D9UA 1XB0A 5C7DA 3D9TA 3OZ1A 1I3OE 3EYLA 5C3KA 5C7CA 1C9QA 2RAXA 3F7GA 1JD5A 4J47A 3UIJA 3T6PA 3UEGA 4KJVA 1OXQA 2QRAA 3UIIA 1E31A 2POIA 3GT9A
chains in the Genus database with same CATH superfamily
4HY0A 3M0AD 4KMPA 4LGEA 4MTIA 3G76A 1F3HA 3F7IA 4J46A 5C84A 1XB1A 1SE0A 3GTAA 3CLXA 4EC4A 4J48A 4HY5A 3HL5A 4WVSA 1JD4A 4J44A 3UECA 3MUPA 3UEFA 2OPZA 3CM2A 5C83A 4MTZA 4KMNA 1G3FA 3UW5A 1XOXA 4A0NA 2OPYA 4WVTA 5C0LA 3UEDA 2I3IA 3UEEA 2UVLA 1OXNA 4KJUA 1OY7A 4MU7A 1QBHA 5C0KA 3F7HA 1G73C 4EB9A 5C7AA 1TFQA 4A0IA 1TFTA 3UIKA 4J3YA 3M0DD 4HY4A 1JD6A 2I3HA 1F9XA 1M4MA 2POPB 1NW9A 1TW6A 2JK7A 3SIPE 3SIQA 2VSLA 1Q4QA 2RAWA 4WVUA 3UEHA 3UIGA 1SDZA 3UW4A 4LGUA 4J45A 3UEIA 3UIHA 2VM5A 5C3HA 3CM7A 5C7BA 3M1DA 4OXCA 4A0JA 2QFAA 3D9UA 1XB0A 5C7DA 3D9TA 3OZ1A 1I3OE 3EYLA 5C3KA 5C7CA 1C9QA 2RAXA 3F7GA 1JD5A 4J47A 3UIJA 3T6PA 3UEGA 4KJVA 1OXQA 2QRAA 3UIIA 1E31A 2POIA 3GT9A
chains in the Genus database with same CATH topology
4HY0A 3M0AD 4KMPA 4LGEA 4MTIA 3G76A 1F3HA 3F7IA 4J46A 5C84A 1XB1A 1SE0A 3GTAA 3CLXA 4EC4A 4J48A 4HY5A 3HL5A 4WVSA 1JD4A 4J44A 3UECA 3MUPA 3UEFA 2OPZA 3CM2A 5C83A 4MTZA 4KMNA 1G3FA 3UW5A 1XOXA 4A0NA 2OPYA 4WVTA 5C0LA 3UEDA 2I3IA 3UEEA 2UVLA 1OXNA 4KJUA 1OY7A 4MU7A 1QBHA 5C0KA 3F7HA 1G73C 4EB9A 5C7AA 1TFQA 4A0IA 1TFTA 3UIKA 4J3YA 3M0DD 4HY4A 1JD6A 2I3HA 1F9XA 1M4MA 2POPB 1NW9A 1TW6A 2JK7A 3SIPE 3SIQA 2VSLA 1Q4QA 2RAWA 4WVUA 3UEHA 3UIGA 1SDZA 3UW4A 4LGUA 4J45A 3UEIA 3UIHA 2VM5A 5C3HA 3CM7A 5C7BA 3M1DA 4OXCA 4A0JA 2QFAA 3D9UA 1XB0A 5C7DA 3D9TA 3OZ1A 1I3OE 3EYLA 5C3KA 5C7CA 1C9QA 2RAXA 3F7GA 1JD5A 4J47A 3UIJA 3T6PA 3UEGA 4KJVA 1OXQA 2QRAA 3UIIA 1E31A 2POIA 3GT9A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4HY0 A;  3M0A D;  4KMP A;  4LGE A;  4MTI A;  3G76 A;  1F3H A;  3F7I A;  4J46 A;  5C84 A;  1XB1 A;  1SE0 A;  3GTA A;  3CLX A;  4EC4 A;  4J48 A;  4HY5 A;  3HL5 A;  4WVS A;  1JD4 A;  4J44 A;  3UEC A;  3MUP A;  3UEF A;  2OPZ A;  3CM2 A;  5C83 A;  4MTZ A;  4KMN A;  1G3F A;  3UW5 A;  1XOX A;  4A0N A;  2OPY A;  4WVT A;  5C0L A;  3UED A;  2I3I A;  3UEE A;  2UVL A;  1OXN A;  4KJU A;  1OY7 A;  4MU7 A;  1QBH A;  5C0K A;  3F7H A;  1G73 C;  4EB9 A;  5C7A A;  1TFQ A;  4A0I A;  1TFT A;  3UIK A;  4J3Y A;  3M0D D;  4HY4 A;  1JD6 A;  2I3H A;  1F9X A;  1M4M A;  2POP B;  1NW9 A;  1TW6 A;  2JK7 A;  3SIP E;  3SIQ A;  2VSL A;  1Q4Q A;  2RAW A;  4WVU A;  3UEH A;  3UIG A;  1SDZ A;  3UW4 A;  4LGU A;  4J45 A;  3UEI A;  3UIH A;  2VM5 A;  5C3H A;  3CM7 A;  5C7B A;  3M1D A;  4OXC A;  4A0J A;  2QFA A;  3D9U A;  1XB0 A;  5C7D A;  3D9T A;  3OZ1 A;  1I3O E;  3EYL A;  5C3K A;  5C7C A;  1C9Q A;  2RAX A;  3F7G A;  1JD5 A;  4J47 A;  3UIJ A;  3T6P A;  3UEG A;  4KJV A;  1OXQ A;  2QRA A;  3UII A;  1E31 A;  2POI A;  3GT9 A; 
#chains in the Genus database with same CATH topology
 4HY0 A;  3M0A D;  4KMP A;  4LGE A;  4MTI A;  3G76 A;  1F3H A;  3F7I A;  4J46 A;  5C84 A;  1XB1 A;  1SE0 A;  3GTA A;  3CLX A;  4EC4 A;  4J48 A;  4HY5 A;  3HL5 A;  4WVS A;  1JD4 A;  4J44 A;  3UEC A;  3MUP A;  3UEF A;  2OPZ A;  3CM2 A;  5C83 A;  4MTZ A;  4KMN A;  1G3F A;  3UW5 A;  1XOX A;  4A0N A;  2OPY A;  4WVT A;  5C0L A;  3UED A;  2I3I A;  3UEE A;  2UVL A;  1OXN A;  4KJU A;  1OY7 A;  4MU7 A;  1QBH A;  5C0K A;  3F7H A;  1G73 C;  4EB9 A;  5C7A A;  1TFQ A;  4A0I A;  1TFT A;  3UIK A;  4J3Y A;  3M0D D;  4HY4 A;  1JD6 A;  2I3H A;  1F9X A;  1M4M A;  2POP B;  1NW9 A;  1TW6 A;  2JK7 A;  3SIP E;  3SIQ A;  2VSL A;  1Q4Q A;  2RAW A;  4WVU A;  3UEH A;  3UIG A;  1SDZ A;  3UW4 A;  4LGU A;  4J45 A;  3UEI A;  3UIH A;  2VM5 A;  5C3H A;  3CM7 A;  5C7B A;  3M1D A;  4OXC A;  4A0J A;  2QFA A;  3D9U A;  1XB0 A;  5C7D A;  3D9T A;  3OZ1 A;  1I3O E;  3EYL A;  5C3K A;  5C7C A;  1C9Q A;  2RAX A;  3F7G A;  1JD5 A;  4J47 A;  3UIJ A;  3T6P A;  3UEG A;  4KJV A;  1OXQ A;  2QRA A;  3UII A;  1E31 A;  2POI A;  3GT9 A; 
#chains in the Genus database with same CATH homology
 4HY0 A;  3M0A D;  4KMP A;  4LGE A;  4MTI A;  3G76 A;  1F3H A;  3F7I A;  4J46 A;  5C84 A;  1XB1 A;  1SE0 A;  3GTA A;  3CLX A;  4EC4 A;  4J48 A;  4HY5 A;  3HL5 A;  4WVS A;  1JD4 A;  4J44 A;  3UEC A;  3MUP A;  3UEF A;  2OPZ A;  3CM2 A;  5C83 A;  4MTZ A;  4KMN A;  1G3F A;  3UW5 A;  1XOX A;  4A0N A;  2OPY A;  4WVT A;  5C0L A;  3UED A;  2I3I A;  3UEE A;  2UVL A;  1OXN A;  4KJU A;  1OY7 A;  4MU7 A;  1QBH A;  5C0K A;  3F7H A;  1G73 C;  4EB9 A;  5C7A A;  1TFQ A;  4A0I A;  1TFT A;  3UIK A;  4J3Y A;  3M0D D;  4HY4 A;  1JD6 A;  2I3H A;  1F9X A;  1M4M A;  2POP B;  1NW9 A;  1TW6 A;  2JK7 A;  3SIP E;  3SIQ A;  2VSL A;  1Q4Q A;  2RAW A;  4WVU A;  3UEH A;  3UIG A;  1SDZ A;  3UW4 A;  4LGU A;  4J45 A;  3UEI A;  3UIH A;  2VM5 A;  5C3H A;  3CM7 A;  5C7B A;  3M1D A;  4OXC A;  4A0J A;  2QFA A;  3D9U A;  1XB0 A;  5C7D A;  3D9T A;  3OZ1 A;  1I3O E;  3EYL A;  5C3K A;  5C7C A;  1C9Q A;  2RAX A;  3F7G A;  1JD5 A;  4J47 A;  3UIJ A;  3T6P A;  3UEG A;  4KJV A;  1OXQ A;  2QRA A;  3UII A;  1E31 A;  2POI A;  3GT9 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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