3M0DD

Crystal structure of the traf1:traf2:ciap2 complex
Total Genus 17
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
17
sequence length
75
structure length
75
Chain Sequence
MLSCELYRMSTYSTFPAGVPVSERSLARAGFYYTGVNDKVKCFCCGLMLDNWKRGDSPTEKHKKLYPSCRFVQSL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal structures of the TRAF2: cIAP2 and the TRAF1: TRAF2: cIAP2 complexes: affinity, specificity, and regulation.
pubmed doi rcsb
molecule tags Signaling protein
source organism Homo sapiens
molecule keywords TNF receptor-associated factor 2
total genus 17
structure length 75
sequence length 75
ec nomenclature ec 2.3.2.27: RING-type E3 ubiquitin transferase.
pdb deposition date 2010-03-02

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
D PF00653 BIR Inhibitor of Apoptosis domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.1170.10 Mainly Alpha Orthogonal Bundle Inhibitor Of Apoptosis Protein (2mihbC-IAP-1); Chain A Inhibitor Of Apoptosis Protein (2mihbC-IAP-1); Chain A 3m0dD00
4MTIA 3UECA 4KMPA 4MTZA 4WVUA 1XOXA 4KJUA 2I3HA 1XB1A 2OPYA 2VSLA 3UIIA 3D9TA 1TW6A 3UEHA 4KJVA 1Q4QA 1TFTA 4LGEA 5C7AA 1JD5A 3MUPA 4WVTA 1OY7A 1M4MA 3M0DD 4A0JA 2VM5A 4J44A 3HL5A 4HY0A 4J48A 3UEFA 4A0IA 3UIGA 1TFQA 3D9UA 3CM2A 1XB0A 3OZ1A 4A0NA 3T6PA 5C83A 3UW4A 5C3HA 1JD4A 4J46A 1E31A 3F7HA 2RAXA 4EB9A 4OXCA 1OXNA 3UIJA 1C9QA 2RAWA 3CLXA 1I3OE 3UIHA 5C0LA 2OPZA 1G3FA 3G76A 3UW5A 1F3HA 3EYLA 5C84A 4J47A 2JK7A 4J3YA 4MU7A 5C7CA 3UEEA 3SIPE 1SDZA 4HY5A 2QFAA 4LGUA 1QBHA 3M0AD 5C7DA 4HY4A 3F7IA 3UEGA 3F7GA 2QRAA 3GT9A 3UIKA 5C7BA 3CM7A 1G73C 5C0KA 2UVLA 1JD6A 5C3KA 3UEIA 2I3IA 3UEDA 2POIA 4J45A 1NW9A 3GTAA 2POPB 4KMNA 4EC4A 4WVSA 3SIQA 1SE0A 1F9XA 1OXQA 3M1DA
chains in the Genus database with same CATH superfamily
4MTIA 3UECA 4KMPA 4MTZA 4WVUA 1XOXA 4KJUA 2I3HA 1XB1A 2OPYA 2VSLA 3UIIA 3D9TA 1TW6A 3UEHA 4KJVA 1Q4QA 1TFTA 4LGEA 5C7AA 1JD5A 3MUPA 4WVTA 1OY7A 1M4MA 3M0DD 4A0JA 2VM5A 4J44A 3HL5A 4HY0A 4J48A 3UEFA 4A0IA 3UIGA 1TFQA 3D9UA 3CM2A 1XB0A 3OZ1A 4A0NA 3T6PA 5C83A 3UW4A 5C3HA 1JD4A 4J46A 1E31A 3F7HA 2RAXA 4EB9A 4OXCA 1OXNA 3UIJA 1C9QA 2RAWA 3CLXA 1I3OE 3UIHA 5C0LA 2OPZA 1G3FA 3G76A 3UW5A 1F3HA 3EYLA 5C84A 4J47A 2JK7A 4J3YA 4MU7A 5C7CA 3UEEA 3SIPE 1SDZA 4HY5A 2QFAA 4LGUA 1QBHA 3M0AD 5C7DA 4HY4A 3F7IA 3UEGA 3F7GA 2QRAA 3GT9A 3UIKA 5C7BA 3CM7A 1G73C 5C0KA 2UVLA 1JD6A 5C3KA 3UEIA 2I3IA 3UEDA 2POIA 4J45A 1NW9A 3GTAA 2POPB 4KMNA 4EC4A 4WVSA 3SIQA 1SE0A 1F9XA 1OXQA 3M1DA
chains in the Genus database with same CATH topology
4MTIA 3UECA 4KMPA 4MTZA 4WVUA 1XOXA 4KJUA 2I3HA 1XB1A 2OPYA 2VSLA 3UIIA 3D9TA 1TW6A 3UEHA 4KJVA 1Q4QA 1TFTA 4LGEA 5C7AA 1JD5A 3MUPA 4WVTA 1OY7A 1M4MA 3M0DD 4A0JA 2VM5A 4J44A 3HL5A 4HY0A 4J48A 3UEFA 4A0IA 3UIGA 1TFQA 3D9UA 3CM2A 1XB0A 3OZ1A 4A0NA 3T6PA 5C83A 3UW4A 5C3HA 1JD4A 4J46A 1E31A 3F7HA 2RAXA 4EB9A 4OXCA 1OXNA 3UIJA 1C9QA 2RAWA 3CLXA 1I3OE 3UIHA 5C0LA 2OPZA 1G3FA 3G76A 3UW5A 1F3HA 3EYLA 5C84A 4J47A 2JK7A 4J3YA 4MU7A 5C7CA 3UEEA 3SIPE 1SDZA 4HY5A 2QFAA 4LGUA 1QBHA 3M0AD 5C7DA 4HY4A 3F7IA 3UEGA 3F7GA 2QRAA 3GT9A 3UIKA 5C7BA 3CM7A 1G73C 5C0KA 2UVLA 1JD6A 5C3KA 3UEIA 2I3IA 3UEDA 2POIA 4J45A 1NW9A 3GTAA 2POPB 4KMNA 4EC4A 4WVSA 3SIQA 1SE0A 1F9XA 1OXQA 3M1DA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4MTI A;  3UEC A;  4KMP A;  4MTZ A;  4WVU A;  1XOX A;  4KJU A;  2I3H A;  1XB1 A;  2OPY A;  2VSL A;  3UII A;  3D9T A;  1TW6 A;  3UEH A;  4KJV A;  1Q4Q A;  1TFT A;  4LGE A;  5C7A A;  1JD5 A;  3MUP A;  4WVT A;  1OY7 A;  1M4M A;  3M0D D;  4A0J A;  2VM5 A;  4J44 A;  3HL5 A;  4HY0 A;  4J48 A;  3UEF A;  4A0I A;  3UIG A;  1TFQ A;  3D9U A;  3CM2 A;  1XB0 A;  3OZ1 A;  4A0N A;  3T6P A;  5C83 A;  3UW4 A;  5C3H A;  1JD4 A;  4J46 A;  1E31 A;  3F7H A;  2RAX A;  4EB9 A;  4OXC A;  1OXN A;  3UIJ A;  1C9Q A;  2RAW A;  3CLX A;  1I3O E;  3UIH A;  5C0L A;  2OPZ A;  1G3F A;  3G76 A;  3UW5 A;  1F3H A;  3EYL A;  5C84 A;  4J47 A;  2JK7 A;  4J3Y A;  4MU7 A;  5C7C A;  3UEE A;  3SIP E;  1SDZ A;  4HY5 A;  2QFA A;  4LGU A;  1QBH A;  3M0A D;  5C7D A;  4HY4 A;  3F7I A;  3UEG A;  3F7G A;  2QRA A;  3GT9 A;  3UIK A;  5C7B A;  3CM7 A;  1G73 C;  5C0K A;  2UVL A;  1JD6 A;  5C3K A;  3UEI A;  2I3I A;  3UED A;  2POI A;  4J45 A;  1NW9 A;  3GTA A;  2POP B;  4KMN A;  4EC4 A;  4WVS A;  3SIQ A;  1SE0 A;  1F9X A;  1OXQ A;  3M1D A; 
#chains in the Genus database with same CATH topology
 4MTI A;  3UEC A;  4KMP A;  4MTZ A;  4WVU A;  1XOX A;  4KJU A;  2I3H A;  1XB1 A;  2OPY A;  2VSL A;  3UII A;  3D9T A;  1TW6 A;  3UEH A;  4KJV A;  1Q4Q A;  1TFT A;  4LGE A;  5C7A A;  1JD5 A;  3MUP A;  4WVT A;  1OY7 A;  1M4M A;  3M0D D;  4A0J A;  2VM5 A;  4J44 A;  3HL5 A;  4HY0 A;  4J48 A;  3UEF A;  4A0I A;  3UIG A;  1TFQ A;  3D9U A;  3CM2 A;  1XB0 A;  3OZ1 A;  4A0N A;  3T6P A;  5C83 A;  3UW4 A;  5C3H A;  1JD4 A;  4J46 A;  1E31 A;  3F7H A;  2RAX A;  4EB9 A;  4OXC A;  1OXN A;  3UIJ A;  1C9Q A;  2RAW A;  3CLX A;  1I3O E;  3UIH A;  5C0L A;  2OPZ A;  1G3F A;  3G76 A;  3UW5 A;  1F3H A;  3EYL A;  5C84 A;  4J47 A;  2JK7 A;  4J3Y A;  4MU7 A;  5C7C A;  3UEE A;  3SIP E;  1SDZ A;  4HY5 A;  2QFA A;  4LGU A;  1QBH A;  3M0A D;  5C7D A;  4HY4 A;  3F7I A;  3UEG A;  3F7G A;  2QRA A;  3GT9 A;  3UIK A;  5C7B A;  3CM7 A;  1G73 C;  5C0K A;  2UVL A;  1JD6 A;  5C3K A;  3UEI A;  2I3I A;  3UED A;  2POI A;  4J45 A;  1NW9 A;  3GTA A;  2POP B;  4KMN A;  4EC4 A;  4WVS A;  3SIQ A;  1SE0 A;  1F9X A;  1OXQ A;  3M1D A; 
#chains in the Genus database with same CATH homology
 4MTI A;  3UEC A;  4KMP A;  4MTZ A;  4WVU A;  1XOX A;  4KJU A;  2I3H A;  1XB1 A;  2OPY A;  2VSL A;  3UII A;  3D9T A;  1TW6 A;  3UEH A;  4KJV A;  1Q4Q A;  1TFT A;  4LGE A;  5C7A A;  1JD5 A;  3MUP A;  4WVT A;  1OY7 A;  1M4M A;  3M0D D;  4A0J A;  2VM5 A;  4J44 A;  3HL5 A;  4HY0 A;  4J48 A;  3UEF A;  4A0I A;  3UIG A;  1TFQ A;  3D9U A;  3CM2 A;  1XB0 A;  3OZ1 A;  4A0N A;  3T6P A;  5C83 A;  3UW4 A;  5C3H A;  1JD4 A;  4J46 A;  1E31 A;  3F7H A;  2RAX A;  4EB9 A;  4OXC A;  1OXN A;  3UIJ A;  1C9Q A;  2RAW A;  3CLX A;  1I3O E;  3UIH A;  5C0L A;  2OPZ A;  1G3F A;  3G76 A;  3UW5 A;  1F3H A;  3EYL A;  5C84 A;  4J47 A;  2JK7 A;  4J3Y A;  4MU7 A;  5C7C A;  3UEE A;  3SIP E;  1SDZ A;  4HY5 A;  2QFA A;  4LGU A;  1QBH A;  3M0A D;  5C7D A;  4HY4 A;  3F7I A;  3UEG A;  3F7G A;  2QRA A;  3GT9 A;  3UIK A;  5C7B A;  3CM7 A;  1G73 C;  5C0K A;  2UVL A;  1JD6 A;  5C3K A;  3UEI A;  2I3I A;  3UED A;  2POI A;  4J45 A;  1NW9 A;  3GTA A;  2POP B;  4KMN A;  4EC4 A;  4WVS A;  3SIQ A;  1SE0 A;  1F9X A;  1OXQ A;  3M1D A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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