3MUPA

Ciap1-bir3 domain in complex with the smac-mimetic compound smac037
Total Genus 25
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
25
sequence length
101
structure length
101
Chain Sequence
SISNLSMQTHAARMRTFMYWPSSVPVQPEQLASAGFYYVGRNDDVKCFCCDGGLRCWESGDDPWVEHAKWFPRCEFLIRMKGQEFVDEIQGRYPHLLEQLL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Recognition of Smac-mimetic compounds by the BIR domain of cIAP1
pubmed doi rcsb
molecule tags Apoptosis inhibitor
source organism Homo sapiens
molecule keywords Baculoviral IAP repeat-containing protein 2
total genus 25
structure length 101
sequence length 101
chains with identical sequence B, C, D
ec nomenclature ec 2.3.2.27: RING-type E3 ubiquitin transferase.
pdb deposition date 2010-05-03

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00653 BIR Inhibitor of Apoptosis domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.1170.10 Mainly Alpha Orthogonal Bundle Inhibitor Of Apoptosis Protein (2mihbC-IAP-1); Chain A Inhibitor Of Apoptosis Protein (2mihbC-IAP-1); Chain A 3mupA00
3CLXA 3CM2A 3M0DD 3UEEA 4A0JA 5C7BA 3UECA 5C7DA 5C83A 2I3IA 3UIGA 4J47A 1NW9A 3M0AD 2OPYA 1JD4A 4KMPA 3UEGA 1XOXA 3M1DA 5C84A 1F3HA 5C0KA 2VSLA 3F7GA 4MTZA 3UEDA 1OXQA 2RAWA 3SIQA 1JD5A 3UEHA 1M4MA 3HL5A 1TW6A 4MTIA 4KMNA 5C3KA 3UEIA 3MUPA 4EC4A 3G76A 4HY5A 1OY7A 4J46A 1TFQA 4J48A 4WVSA 2I3HA 1JD6A 4A0NA 1C9QA 4A0IA 1Q4QA 4WVTA 4LGUA 3UIIA 4MU7A 5C7CA 3SIPE 3UIHA 1OXNA 2RAXA 3UW5A 4OXCA 1QBHA 4J3YA 2UVLA 3CM7A 2POIA 4WVUA 1G73C 1I3OE 5C0LA 2JK7A 1SE0A 3UEFA 3UIKA 5C7AA 1G3FA 3F7IA 3D9UA 4HY4A 2QFAA 3T6PA 3D9TA 2OPZA 4LGEA 2QRAA 1XB0A 4KJUA 3F7HA 4KJVA 1SDZA 3OZ1A 4J45A 4EB9A 2VM5A 2POPB 4J44A 1E31A 1TFTA 3GTAA 5C3HA 3EYLA 1F9XA 3UW4A 1XB1A 3GT9A 4HY0A 3UIJA
chains in the Genus database with same CATH superfamily
3CLXA 3CM2A 3M0DD 3UEEA 4A0JA 5C7BA 3UECA 5C7DA 5C83A 2I3IA 3UIGA 4J47A 1NW9A 3M0AD 2OPYA 1JD4A 4KMPA 3UEGA 1XOXA 3M1DA 5C84A 1F3HA 5C0KA 2VSLA 3F7GA 4MTZA 3UEDA 1OXQA 2RAWA 3SIQA 1JD5A 3UEHA 1M4MA 3HL5A 1TW6A 4MTIA 4KMNA 5C3KA 3UEIA 3MUPA 4EC4A 3G76A 4HY5A 1OY7A 4J46A 1TFQA 4J48A 4WVSA 2I3HA 1JD6A 4A0NA 1C9QA 4A0IA 1Q4QA 4WVTA 4LGUA 3UIIA 4MU7A 5C7CA 3SIPE 3UIHA 1OXNA 2RAXA 3UW5A 4OXCA 1QBHA 4J3YA 2UVLA 3CM7A 2POIA 4WVUA 1G73C 1I3OE 5C0LA 2JK7A 1SE0A 3UEFA 3UIKA 5C7AA 1G3FA 3F7IA 3D9UA 4HY4A 2QFAA 3T6PA 3D9TA 2OPZA 4LGEA 2QRAA 1XB0A 4KJUA 3F7HA 4KJVA 1SDZA 3OZ1A 4J45A 4EB9A 2VM5A 2POPB 4J44A 1E31A 1TFTA 3GTAA 5C3HA 3EYLA 1F9XA 3UW4A 1XB1A 3GT9A 4HY0A 3UIJA
chains in the Genus database with same CATH topology
3CLXA 3CM2A 3M0DD 3UEEA 4A0JA 5C7BA 3UECA 5C7DA 5C83A 2I3IA 3UIGA 4J47A 1NW9A 3M0AD 2OPYA 1JD4A 4KMPA 3UEGA 1XOXA 3M1DA 5C84A 1F3HA 5C0KA 2VSLA 3F7GA 4MTZA 3UEDA 1OXQA 2RAWA 3SIQA 1JD5A 3UEHA 1M4MA 3HL5A 1TW6A 4MTIA 4KMNA 5C3KA 3UEIA 3MUPA 4EC4A 3G76A 4HY5A 1OY7A 4J46A 1TFQA 4J48A 4WVSA 2I3HA 1JD6A 4A0NA 1C9QA 4A0IA 1Q4QA 4WVTA 4LGUA 3UIIA 4MU7A 5C7CA 3SIPE 3UIHA 1OXNA 2RAXA 3UW5A 4OXCA 1QBHA 4J3YA 2UVLA 3CM7A 2POIA 4WVUA 1G73C 1I3OE 5C0LA 2JK7A 1SE0A 3UEFA 3UIKA 5C7AA 1G3FA 3F7IA 3D9UA 4HY4A 2QFAA 3T6PA 3D9TA 2OPZA 4LGEA 2QRAA 1XB0A 4KJUA 3F7HA 4KJVA 1SDZA 3OZ1A 4J45A 4EB9A 2VM5A 2POPB 4J44A 1E31A 1TFTA 3GTAA 5C3HA 3EYLA 1F9XA 3UW4A 1XB1A 3GT9A 4HY0A 3UIJA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3CLX A;  3CM2 A;  3M0D D;  3UEE A;  4A0J A;  5C7B A;  3UEC A;  5C7D A;  5C83 A;  2I3I A;  3UIG A;  4J47 A;  1NW9 A;  3M0A D;  2OPY A;  1JD4 A;  4KMP A;  3UEG A;  1XOX A;  3M1D A;  5C84 A;  1F3H A;  5C0K A;  2VSL A;  3F7G A;  4MTZ A;  3UED A;  1OXQ A;  2RAW A;  3SIQ A;  1JD5 A;  3UEH A;  1M4M A;  3HL5 A;  1TW6 A;  4MTI A;  4KMN A;  5C3K A;  3UEI A;  3MUP A;  4EC4 A;  3G76 A;  4HY5 A;  1OY7 A;  4J46 A;  1TFQ A;  4J48 A;  4WVS A;  2I3H A;  1JD6 A;  4A0N A;  1C9Q A;  4A0I A;  1Q4Q A;  4WVT A;  4LGU A;  3UII A;  4MU7 A;  5C7C A;  3SIP E;  3UIH A;  1OXN A;  2RAX A;  3UW5 A;  4OXC A;  1QBH A;  4J3Y A;  2UVL A;  3CM7 A;  2POI A;  4WVU A;  1G73 C;  1I3O E;  5C0L A;  2JK7 A;  1SE0 A;  3UEF A;  3UIK A;  5C7A A;  1G3F A;  3F7I A;  3D9U A;  4HY4 A;  2QFA A;  3T6P A;  3D9T A;  2OPZ A;  4LGE A;  2QRA A;  1XB0 A;  4KJU A;  3F7H A;  4KJV A;  1SDZ A;  3OZ1 A;  4J45 A;  4EB9 A;  2VM5 A;  2POP B;  4J44 A;  1E31 A;  1TFT A;  3GTA A;  5C3H A;  3EYL A;  1F9X A;  3UW4 A;  1XB1 A;  3GT9 A;  4HY0 A;  3UIJ A; 
#chains in the Genus database with same CATH topology
 3CLX A;  3CM2 A;  3M0D D;  3UEE A;  4A0J A;  5C7B A;  3UEC A;  5C7D A;  5C83 A;  2I3I A;  3UIG A;  4J47 A;  1NW9 A;  3M0A D;  2OPY A;  1JD4 A;  4KMP A;  3UEG A;  1XOX A;  3M1D A;  5C84 A;  1F3H A;  5C0K A;  2VSL A;  3F7G A;  4MTZ A;  3UED A;  1OXQ A;  2RAW A;  3SIQ A;  1JD5 A;  3UEH A;  1M4M A;  3HL5 A;  1TW6 A;  4MTI A;  4KMN A;  5C3K A;  3UEI A;  3MUP A;  4EC4 A;  3G76 A;  4HY5 A;  1OY7 A;  4J46 A;  1TFQ A;  4J48 A;  4WVS A;  2I3H A;  1JD6 A;  4A0N A;  1C9Q A;  4A0I A;  1Q4Q A;  4WVT A;  4LGU A;  3UII A;  4MU7 A;  5C7C A;  3SIP E;  3UIH A;  1OXN A;  2RAX A;  3UW5 A;  4OXC A;  1QBH A;  4J3Y A;  2UVL A;  3CM7 A;  2POI A;  4WVU A;  1G73 C;  1I3O E;  5C0L A;  2JK7 A;  1SE0 A;  3UEF A;  3UIK A;  5C7A A;  1G3F A;  3F7I A;  3D9U A;  4HY4 A;  2QFA A;  3T6P A;  3D9T A;  2OPZ A;  4LGE A;  2QRA A;  1XB0 A;  4KJU A;  3F7H A;  4KJV A;  1SDZ A;  3OZ1 A;  4J45 A;  4EB9 A;  2VM5 A;  2POP B;  4J44 A;  1E31 A;  1TFT A;  3GTA A;  5C3H A;  3EYL A;  1F9X A;  3UW4 A;  1XB1 A;  3GT9 A;  4HY0 A;  3UIJ A; 
#chains in the Genus database with same CATH homology
 3CLX A;  3CM2 A;  3M0D D;  3UEE A;  4A0J A;  5C7B A;  3UEC A;  5C7D A;  5C83 A;  2I3I A;  3UIG A;  4J47 A;  1NW9 A;  3M0A D;  2OPY A;  1JD4 A;  4KMP A;  3UEG A;  1XOX A;  3M1D A;  5C84 A;  1F3H A;  5C0K A;  2VSL A;  3F7G A;  4MTZ A;  3UED A;  1OXQ A;  2RAW A;  3SIQ A;  1JD5 A;  3UEH A;  1M4M A;  3HL5 A;  1TW6 A;  4MTI A;  4KMN A;  5C3K A;  3UEI A;  3MUP A;  4EC4 A;  3G76 A;  4HY5 A;  1OY7 A;  4J46 A;  1TFQ A;  4J48 A;  4WVS A;  2I3H A;  1JD6 A;  4A0N A;  1C9Q A;  4A0I A;  1Q4Q A;  4WVT A;  4LGU A;  3UII A;  4MU7 A;  5C7C A;  3SIP E;  3UIH A;  1OXN A;  2RAX A;  3UW5 A;  4OXC A;  1QBH A;  4J3Y A;  2UVL A;  3CM7 A;  2POI A;  4WVU A;  1G73 C;  1I3O E;  5C0L A;  2JK7 A;  1SE0 A;  3UEF A;  3UIK A;  5C7A A;  1G3F A;  3F7I A;  3D9U A;  4HY4 A;  2QFA A;  3T6P A;  3D9T A;  2OPZ A;  4LGE A;  2QRA A;  1XB0 A;  4KJU A;  3F7H A;  4KJV A;  1SDZ A;  3OZ1 A;  4J45 A;  4EB9 A;  2VM5 A;  2POP B;  4J44 A;  1E31 A;  1TFT A;  3GTA A;  5C3H A;  3EYL A;  1F9X A;  3UW4 A;  1XB1 A;  3GT9 A;  4HY0 A;  3UIJ A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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