3OZ1A

Ciap1-bir3 domain in complex with the smac-mimetic compound smac066
Total Genus 27
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
27
sequence length
103
structure length
103
Chain Sequence
FSISNLSMQTHAARMRTFMYWPSSVPVQPEQLASAGFYYVGRNDDVKCFCCDGGLRCWESGDDPWVEHAKWFPRCEFLIRMKGQEFVDEIQGRYPHLLEQLLS
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Recognition of Smac-mimetic compounds by the BIR3 domain of cIAP1
pubmed doi rcsb
molecule tags Apoptosis inhibitor
source organism Homo sapiens
molecule keywords Baculoviral IAP repeat-containing protein 2
total genus 27
structure length 103
sequence length 103
chains with identical sequence B, C, D
ec nomenclature ec 2.3.2.27: RING-type E3 ubiquitin transferase.
pdb deposition date 2010-09-24

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00653 BIR Inhibitor of Apoptosis domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.1170.10 Mainly Alpha Orthogonal Bundle Inhibitor Of Apoptosis Protein (2mihbC-IAP-1); Chain A Inhibitor Of Apoptosis Protein (2mihbC-IAP-1); Chain A 3oz1A00
1SDZA 4WVUA 3GT9A 4J45A 4HY4A 3HL5A 1NW9A 4MTIA 1I3OE 1OXQA 3UEGA 4A0NA 2UVLA 4KMPA 1JD6A 3UEIA 3UECA 5C7BA 3GTAA 1F3HA 4WVTA 5C7CA 1JD4A 3UEFA 2OPZA 3UIHA 5C7AA 1XB0A 2I3HA 4HY5A 5C0LA 3EYLA 2RAXA 4J3YA 3D9TA 1XOXA 5C0KA 1TFTA 4J46A 2VM5A 4KJVA 5C84A 2QFAA 5C7DA 3UEEA 3UEHA 1QBHA 1G3FA 1TFQA 1G73C 1OXNA 4MTZA 1F9XA 1JD5A 5C3HA 1C9QA 2JK7A 1M4MA 3CLXA 3G76A 3CM2A 4WVSA 2VSLA 1XB1A 4KJUA 3SIQA 2RAWA 3UIJA 4A0IA 3CM7A 4LGEA 4OXCA 3T6PA 3UIIA 3UW4A 4HY0A 1SE0A 5C83A 3M0DD 1TW6A 3UEDA 3UIGA 2QRAA 3UIKA 3UW5A 3M1DA 4J48A 4EC4A 3F7GA 1OY7A 3SIPE 3MUPA 4EB9A 4MU7A 3M0AD 4A0JA 1Q4QA 5C3KA 2POPB 1E31A 4J47A 3F7HA 4LGUA 3F7IA 2POIA 4J44A 3D9UA 3OZ1A 2I3IA 4KMNA 2OPYA
chains in the Genus database with same CATH superfamily
1SDZA 4WVUA 3GT9A 4J45A 4HY4A 3HL5A 1NW9A 4MTIA 1I3OE 1OXQA 3UEGA 4A0NA 2UVLA 4KMPA 1JD6A 3UEIA 3UECA 5C7BA 3GTAA 1F3HA 4WVTA 5C7CA 1JD4A 3UEFA 2OPZA 3UIHA 5C7AA 1XB0A 2I3HA 4HY5A 5C0LA 3EYLA 2RAXA 4J3YA 3D9TA 1XOXA 5C0KA 1TFTA 4J46A 2VM5A 4KJVA 5C84A 2QFAA 5C7DA 3UEEA 3UEHA 1QBHA 1G3FA 1TFQA 1G73C 1OXNA 4MTZA 1F9XA 1JD5A 5C3HA 1C9QA 2JK7A 1M4MA 3CLXA 3G76A 3CM2A 4WVSA 2VSLA 1XB1A 4KJUA 3SIQA 2RAWA 3UIJA 4A0IA 3CM7A 4LGEA 4OXCA 3T6PA 3UIIA 3UW4A 4HY0A 1SE0A 5C83A 3M0DD 1TW6A 3UEDA 3UIGA 2QRAA 3UIKA 3UW5A 3M1DA 4J48A 4EC4A 3F7GA 1OY7A 3SIPE 3MUPA 4EB9A 4MU7A 3M0AD 4A0JA 1Q4QA 5C3KA 2POPB 1E31A 4J47A 3F7HA 4LGUA 3F7IA 2POIA 4J44A 3D9UA 3OZ1A 2I3IA 4KMNA 2OPYA
chains in the Genus database with same CATH topology
1SDZA 4WVUA 3GT9A 4J45A 4HY4A 3HL5A 1NW9A 4MTIA 1I3OE 1OXQA 3UEGA 4A0NA 2UVLA 4KMPA 1JD6A 3UEIA 3UECA 5C7BA 3GTAA 1F3HA 4WVTA 5C7CA 1JD4A 3UEFA 2OPZA 3UIHA 5C7AA 1XB0A 2I3HA 4HY5A 5C0LA 3EYLA 2RAXA 4J3YA 3D9TA 1XOXA 5C0KA 1TFTA 4J46A 2VM5A 4KJVA 5C84A 2QFAA 5C7DA 3UEEA 3UEHA 1QBHA 1G3FA 1TFQA 1G73C 1OXNA 4MTZA 1F9XA 1JD5A 5C3HA 1C9QA 2JK7A 1M4MA 3CLXA 3G76A 3CM2A 4WVSA 2VSLA 1XB1A 4KJUA 3SIQA 2RAWA 3UIJA 4A0IA 3CM7A 4LGEA 4OXCA 3T6PA 3UIIA 3UW4A 4HY0A 1SE0A 5C83A 3M0DD 1TW6A 3UEDA 3UIGA 2QRAA 3UIKA 3UW5A 3M1DA 4J48A 4EC4A 3F7GA 1OY7A 3SIPE 3MUPA 4EB9A 4MU7A 3M0AD 4A0JA 1Q4QA 5C3KA 2POPB 1E31A 4J47A 3F7HA 4LGUA 3F7IA 2POIA 4J44A 3D9UA 3OZ1A 2I3IA 4KMNA 2OPYA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1SDZ A;  4WVU A;  3GT9 A;  4J45 A;  4HY4 A;  3HL5 A;  1NW9 A;  4MTI A;  1I3O E;  1OXQ A;  3UEG A;  4A0N A;  2UVL A;  4KMP A;  1JD6 A;  3UEI A;  3UEC A;  5C7B A;  3GTA A;  1F3H A;  4WVT A;  5C7C A;  1JD4 A;  3UEF A;  2OPZ A;  3UIH A;  5C7A A;  1XB0 A;  2I3H A;  4HY5 A;  5C0L A;  3EYL A;  2RAX A;  4J3Y A;  3D9T A;  1XOX A;  5C0K A;  1TFT A;  4J46 A;  2VM5 A;  4KJV A;  5C84 A;  2QFA A;  5C7D A;  3UEE A;  3UEH A;  1QBH A;  1G3F A;  1TFQ A;  1G73 C;  1OXN A;  4MTZ A;  1F9X A;  1JD5 A;  5C3H A;  1C9Q A;  2JK7 A;  1M4M A;  3CLX A;  3G76 A;  3CM2 A;  4WVS A;  2VSL A;  1XB1 A;  4KJU A;  3SIQ A;  2RAW A;  3UIJ A;  4A0I A;  3CM7 A;  4LGE A;  4OXC A;  3T6P A;  3UII A;  3UW4 A;  4HY0 A;  1SE0 A;  5C83 A;  3M0D D;  1TW6 A;  3UED A;  3UIG A;  2QRA A;  3UIK A;  3UW5 A;  3M1D A;  4J48 A;  4EC4 A;  3F7G A;  1OY7 A;  3SIP E;  3MUP A;  4EB9 A;  4MU7 A;  3M0A D;  4A0J A;  1Q4Q A;  5C3K A;  2POP B;  1E31 A;  4J47 A;  3F7H A;  4LGU A;  3F7I A;  2POI A;  4J44 A;  3D9U A;  3OZ1 A;  2I3I A;  4KMN A;  2OPY A; 
#chains in the Genus database with same CATH topology
 1SDZ A;  4WVU A;  3GT9 A;  4J45 A;  4HY4 A;  3HL5 A;  1NW9 A;  4MTI A;  1I3O E;  1OXQ A;  3UEG A;  4A0N A;  2UVL A;  4KMP A;  1JD6 A;  3UEI A;  3UEC A;  5C7B A;  3GTA A;  1F3H A;  4WVT A;  5C7C A;  1JD4 A;  3UEF A;  2OPZ A;  3UIH A;  5C7A A;  1XB0 A;  2I3H A;  4HY5 A;  5C0L A;  3EYL A;  2RAX A;  4J3Y A;  3D9T A;  1XOX A;  5C0K A;  1TFT A;  4J46 A;  2VM5 A;  4KJV A;  5C84 A;  2QFA A;  5C7D A;  3UEE A;  3UEH A;  1QBH A;  1G3F A;  1TFQ A;  1G73 C;  1OXN A;  4MTZ A;  1F9X A;  1JD5 A;  5C3H A;  1C9Q A;  2JK7 A;  1M4M A;  3CLX A;  3G76 A;  3CM2 A;  4WVS A;  2VSL A;  1XB1 A;  4KJU A;  3SIQ A;  2RAW A;  3UIJ A;  4A0I A;  3CM7 A;  4LGE A;  4OXC A;  3T6P A;  3UII A;  3UW4 A;  4HY0 A;  1SE0 A;  5C83 A;  3M0D D;  1TW6 A;  3UED A;  3UIG A;  2QRA A;  3UIK A;  3UW5 A;  3M1D A;  4J48 A;  4EC4 A;  3F7G A;  1OY7 A;  3SIP E;  3MUP A;  4EB9 A;  4MU7 A;  3M0A D;  4A0J A;  1Q4Q A;  5C3K A;  2POP B;  1E31 A;  4J47 A;  3F7H A;  4LGU A;  3F7I A;  2POI A;  4J44 A;  3D9U A;  3OZ1 A;  2I3I A;  4KMN A;  2OPY A; 
#chains in the Genus database with same CATH homology
 1SDZ A;  4WVU A;  3GT9 A;  4J45 A;  4HY4 A;  3HL5 A;  1NW9 A;  4MTI A;  1I3O E;  1OXQ A;  3UEG A;  4A0N A;  2UVL A;  4KMP A;  1JD6 A;  3UEI A;  3UEC A;  5C7B A;  3GTA A;  1F3H A;  4WVT A;  5C7C A;  1JD4 A;  3UEF A;  2OPZ A;  3UIH A;  5C7A A;  1XB0 A;  2I3H A;  4HY5 A;  5C0L A;  3EYL A;  2RAX A;  4J3Y A;  3D9T A;  1XOX A;  5C0K A;  1TFT A;  4J46 A;  2VM5 A;  4KJV A;  5C84 A;  2QFA A;  5C7D A;  3UEE A;  3UEH A;  1QBH A;  1G3F A;  1TFQ A;  1G73 C;  1OXN A;  4MTZ A;  1F9X A;  1JD5 A;  5C3H A;  1C9Q A;  2JK7 A;  1M4M A;  3CLX A;  3G76 A;  3CM2 A;  4WVS A;  2VSL A;  1XB1 A;  4KJU A;  3SIQ A;  2RAW A;  3UIJ A;  4A0I A;  3CM7 A;  4LGE A;  4OXC A;  3T6P A;  3UII A;  3UW4 A;  4HY0 A;  1SE0 A;  5C83 A;  3M0D D;  1TW6 A;  3UED A;  3UIG A;  2QRA A;  3UIK A;  3UW5 A;  3M1D A;  4J48 A;  4EC4 A;  3F7G A;  1OY7 A;  3SIP E;  3MUP A;  4EB9 A;  4MU7 A;  3M0A D;  4A0J A;  1Q4Q A;  5C3K A;  2POP B;  1E31 A;  4J47 A;  3F7H A;  4LGU A;  3F7I A;  2POI A;  4J44 A;  3D9U A;  3OZ1 A;  2I3I A;  4KMN A;  2OPY A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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