3SIPE

Crystal structure of drice and diap1-bir1 complex
Total Genus 22
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
22
sequence length
100
structure length
100
Chain Sequence
DLNREETRLKTFTDWPLDWLDKRQLAQTGMYFTHAGDKVKCFFCGVEIGSWEQEDQPVPEHQRWSPNCPLLRRRTTNNVPINAEALDRILPPISYDICGA
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural mechanisms of DIAP1 auto-inhibition and DIAP1-mediated inhibition of drICE.
pubmed doi rcsb
molecule tags Hydrolase/ligase/hydrolase
source organism Drosophila melanogaster
molecule keywords Caspase
total genus 22
structure length 100
sequence length 100
chains with identical sequence F
ec nomenclature ec 2.3.2.27: RING-type E3 ubiquitin transferase.
pdb deposition date 2011-06-20

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
E PF00653 BIR Inhibitor of Apoptosis domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.1170.10 Mainly Alpha Orthogonal Bundle Inhibitor Of Apoptosis Protein (2mihbC-IAP-1); Chain A Inhibitor Of Apoptosis Protein (2mihbC-IAP-1); Chain A 3sipE00
1XOXA 3D9UA 3UIKA 3UW4A 4A0JA 1M4MA 4KMNA 4KMPA 4A0NA 3UEIA 1F3HA 4MTZA 5C3KA 4OXCA 3CLXA 3SIQA 1G3FA 2VM5A 1JD6A 3G76A 4HY4A 4WVTA 3F7HA 4KJUA 3UEEA 1QBHA 3T6PA 5C7CA 2QFAA 3UIIA 3UIHA 1NW9A 2UVLA 4J46A 1SDZA 4WVUA 1OXNA 3M1DA 2I3IA 4J3YA 2OPYA 1TFTA 2RAXA 4MU7A 3D9TA 4J48A 5C7AA 2POIA 2JK7A 3UECA 3UEFA 3EYLA 5C0KA 1I3OE 1JD4A 3UEGA 1TFQA 5C7BA 4LGUA 3GTAA 1E31A 4A0IA 5C83A 4KJVA 2VSLA 5C3HA 3UEDA 1OXQA 1F9XA 1JD5A 3UEHA 1OY7A 4WVSA 2POPB 1XB1A 5C7DA 4J44A 1TW6A 3SIPE 4HY0A 1SE0A 3CM2A 3M0AD 3M0DD 3F7GA 4J45A 4MTIA 2OPZA 3HL5A 3CM7A 4HY5A 3UIJA 4EC4A 1Q4QA 4J47A 4LGEA 4EB9A 1XB0A 3F7IA 1G73C 5C84A 3UW5A 1C9QA 3GT9A 5C0LA 3OZ1A 3UIGA 2RAWA 2QRAA 3MUPA 2I3HA
chains in the Genus database with same CATH superfamily
1XOXA 3D9UA 3UIKA 3UW4A 4A0JA 1M4MA 4KMNA 4KMPA 4A0NA 3UEIA 1F3HA 4MTZA 5C3KA 4OXCA 3CLXA 3SIQA 1G3FA 2VM5A 1JD6A 3G76A 4HY4A 4WVTA 3F7HA 4KJUA 3UEEA 1QBHA 3T6PA 5C7CA 2QFAA 3UIIA 3UIHA 1NW9A 2UVLA 4J46A 1SDZA 4WVUA 1OXNA 3M1DA 2I3IA 4J3YA 2OPYA 1TFTA 2RAXA 4MU7A 3D9TA 4J48A 5C7AA 2POIA 2JK7A 3UECA 3UEFA 3EYLA 5C0KA 1I3OE 1JD4A 3UEGA 1TFQA 5C7BA 4LGUA 3GTAA 1E31A 4A0IA 5C83A 4KJVA 2VSLA 5C3HA 3UEDA 1OXQA 1F9XA 1JD5A 3UEHA 1OY7A 4WVSA 2POPB 1XB1A 5C7DA 4J44A 1TW6A 3SIPE 4HY0A 1SE0A 3CM2A 3M0AD 3M0DD 3F7GA 4J45A 4MTIA 2OPZA 3HL5A 3CM7A 4HY5A 3UIJA 4EC4A 1Q4QA 4J47A 4LGEA 4EB9A 1XB0A 3F7IA 1G73C 5C84A 3UW5A 1C9QA 3GT9A 5C0LA 3OZ1A 3UIGA 2RAWA 2QRAA 3MUPA 2I3HA
chains in the Genus database with same CATH topology
1XOXA 3D9UA 3UIKA 3UW4A 4A0JA 1M4MA 4KMNA 4KMPA 4A0NA 3UEIA 1F3HA 4MTZA 5C3KA 4OXCA 3CLXA 3SIQA 1G3FA 2VM5A 1JD6A 3G76A 4HY4A 4WVTA 3F7HA 4KJUA 3UEEA 1QBHA 3T6PA 5C7CA 2QFAA 3UIIA 3UIHA 1NW9A 2UVLA 4J46A 1SDZA 4WVUA 1OXNA 3M1DA 2I3IA 4J3YA 2OPYA 1TFTA 2RAXA 4MU7A 3D9TA 4J48A 5C7AA 2POIA 2JK7A 3UECA 3UEFA 3EYLA 5C0KA 1I3OE 1JD4A 3UEGA 1TFQA 5C7BA 4LGUA 3GTAA 1E31A 4A0IA 5C83A 4KJVA 2VSLA 5C3HA 3UEDA 1OXQA 1F9XA 1JD5A 3UEHA 1OY7A 4WVSA 2POPB 1XB1A 5C7DA 4J44A 1TW6A 3SIPE 4HY0A 1SE0A 3CM2A 3M0AD 3M0DD 3F7GA 4J45A 4MTIA 2OPZA 3HL5A 3CM7A 4HY5A 3UIJA 4EC4A 1Q4QA 4J47A 4LGEA 4EB9A 1XB0A 3F7IA 1G73C 5C84A 3UW5A 1C9QA 3GT9A 5C0LA 3OZ1A 3UIGA 2RAWA 2QRAA 3MUPA 2I3HA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1XOX A;  3D9U A;  3UIK A;  3UW4 A;  4A0J A;  1M4M A;  4KMN A;  4KMP A;  4A0N A;  3UEI A;  1F3H A;  4MTZ A;  5C3K A;  4OXC A;  3CLX A;  3SIQ A;  1G3F A;  2VM5 A;  1JD6 A;  3G76 A;  4HY4 A;  4WVT A;  3F7H A;  4KJU A;  3UEE A;  1QBH A;  3T6P A;  5C7C A;  2QFA A;  3UII A;  3UIH A;  1NW9 A;  2UVL A;  4J46 A;  1SDZ A;  4WVU A;  1OXN A;  3M1D A;  2I3I A;  4J3Y A;  2OPY A;  1TFT A;  2RAX A;  4MU7 A;  3D9T A;  4J48 A;  5C7A A;  2POI A;  2JK7 A;  3UEC A;  3UEF A;  3EYL A;  5C0K A;  1I3O E;  1JD4 A;  3UEG A;  1TFQ A;  5C7B A;  4LGU A;  3GTA A;  1E31 A;  4A0I A;  5C83 A;  4KJV A;  2VSL A;  5C3H A;  3UED A;  1OXQ A;  1F9X A;  1JD5 A;  3UEH A;  1OY7 A;  4WVS A;  2POP B;  1XB1 A;  5C7D A;  4J44 A;  1TW6 A;  3SIP E;  4HY0 A;  1SE0 A;  3CM2 A;  3M0A D;  3M0D D;  3F7G A;  4J45 A;  4MTI A;  2OPZ A;  3HL5 A;  3CM7 A;  4HY5 A;  3UIJ A;  4EC4 A;  1Q4Q A;  4J47 A;  4LGE A;  4EB9 A;  1XB0 A;  3F7I A;  1G73 C;  5C84 A;  3UW5 A;  1C9Q A;  3GT9 A;  5C0L A;  3OZ1 A;  3UIG A;  2RAW A;  2QRA A;  3MUP A;  2I3H A; 
#chains in the Genus database with same CATH topology
 1XOX A;  3D9U A;  3UIK A;  3UW4 A;  4A0J A;  1M4M A;  4KMN A;  4KMP A;  4A0N A;  3UEI A;  1F3H A;  4MTZ A;  5C3K A;  4OXC A;  3CLX A;  3SIQ A;  1G3F A;  2VM5 A;  1JD6 A;  3G76 A;  4HY4 A;  4WVT A;  3F7H A;  4KJU A;  3UEE A;  1QBH A;  3T6P A;  5C7C A;  2QFA A;  3UII A;  3UIH A;  1NW9 A;  2UVL A;  4J46 A;  1SDZ A;  4WVU A;  1OXN A;  3M1D A;  2I3I A;  4J3Y A;  2OPY A;  1TFT A;  2RAX A;  4MU7 A;  3D9T A;  4J48 A;  5C7A A;  2POI A;  2JK7 A;  3UEC A;  3UEF A;  3EYL A;  5C0K A;  1I3O E;  1JD4 A;  3UEG A;  1TFQ A;  5C7B A;  4LGU A;  3GTA A;  1E31 A;  4A0I A;  5C83 A;  4KJV A;  2VSL A;  5C3H A;  3UED A;  1OXQ A;  1F9X A;  1JD5 A;  3UEH A;  1OY7 A;  4WVS A;  2POP B;  1XB1 A;  5C7D A;  4J44 A;  1TW6 A;  3SIP E;  4HY0 A;  1SE0 A;  3CM2 A;  3M0A D;  3M0D D;  3F7G A;  4J45 A;  4MTI A;  2OPZ A;  3HL5 A;  3CM7 A;  4HY5 A;  3UIJ A;  4EC4 A;  1Q4Q A;  4J47 A;  4LGE A;  4EB9 A;  1XB0 A;  3F7I A;  1G73 C;  5C84 A;  3UW5 A;  1C9Q A;  3GT9 A;  5C0L A;  3OZ1 A;  3UIG A;  2RAW A;  2QRA A;  3MUP A;  2I3H A; 
#chains in the Genus database with same CATH homology
 1XOX A;  3D9U A;  3UIK A;  3UW4 A;  4A0J A;  1M4M A;  4KMN A;  4KMP A;  4A0N A;  3UEI A;  1F3H A;  4MTZ A;  5C3K A;  4OXC A;  3CLX A;  3SIQ A;  1G3F A;  2VM5 A;  1JD6 A;  3G76 A;  4HY4 A;  4WVT A;  3F7H A;  4KJU A;  3UEE A;  1QBH A;  3T6P A;  5C7C A;  2QFA A;  3UII A;  3UIH A;  1NW9 A;  2UVL A;  4J46 A;  1SDZ A;  4WVU A;  1OXN A;  3M1D A;  2I3I A;  4J3Y A;  2OPY A;  1TFT A;  2RAX A;  4MU7 A;  3D9T A;  4J48 A;  5C7A A;  2POI A;  2JK7 A;  3UEC A;  3UEF A;  3EYL A;  5C0K A;  1I3O E;  1JD4 A;  3UEG A;  1TFQ A;  5C7B A;  4LGU A;  3GTA A;  1E31 A;  4A0I A;  5C83 A;  4KJV A;  2VSL A;  5C3H A;  3UED A;  1OXQ A;  1F9X A;  1JD5 A;  3UEH A;  1OY7 A;  4WVS A;  2POP B;  1XB1 A;  5C7D A;  4J44 A;  1TW6 A;  3SIP E;  4HY0 A;  1SE0 A;  3CM2 A;  3M0A D;  3M0D D;  3F7G A;  4J45 A;  4MTI A;  2OPZ A;  3HL5 A;  3CM7 A;  4HY5 A;  3UIJ A;  4EC4 A;  1Q4Q A;  4J47 A;  4LGE A;  4EB9 A;  1XB0 A;  3F7I A;  1G73 C;  5C84 A;  3UW5 A;  1C9Q A;  3GT9 A;  5C0L A;  3OZ1 A;  3UIG A;  2RAW A;  2QRA A;  3MUP A;  2I3H A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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