3SIQA

Crystal structure of autoinhibited diap1-bir1 domain
Total Genus 26
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
26
sequence length
125
structure length
103
Chain Sequence
ASVVPIRMNDLNREETRLKTFTDWPLDWLDKRQLAQTGMYFTHAGDKVKCFFCGVEIGSWEQEDQPVPEHQRWSPNCPLLRRRTTNNVPINAEALDRILPPIS
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural mechanisms of DIAP1 auto-inhibition and DIAP1-mediated inhibition of drICE.
pubmed doi rcsb
molecule tags Ligase
source organism Drosophila melanogaster
molecule keywords Apoptosis 1 inhibitor
total genus 26
structure length 103
sequence length 125
chains with identical sequence B, C, D, E, F
ec nomenclature ec 2.3.2.27: RING-type E3 ubiquitin transferase.
pdb deposition date 2011-06-20

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00653 BIR Inhibitor of Apoptosis domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.1170.10 Mainly Alpha Orthogonal Bundle Inhibitor Of Apoptosis Protein (2mihbC-IAP-1); Chain A Inhibitor Of Apoptosis Protein (2mihbC-IAP-1); Chain A 3siqA00
4J3YA 2RAWA 3D9UA 3D9TA 3T6PA 5C83A 4A0IA 1XB1A 1SE0A 1C9QA 3UW5A 3M0DD 3HL5A 2VSLA 5C7AA 4EC4A 3CM7A 1JD6A 4A0NA 3F7GA 1NW9A 2UVLA 5C3KA 4MTZA 3F7IA 1M4MA 3UEIA 2I3IA 2POIA 1OXNA 2QRAA 4A0JA 3UIHA 4LGUA 3UECA 3UEDA 4EB9A 4HY4A 1OXQA 2RAXA 3EYLA 4J48A 5C0LA 4WVUA 1TFTA 3MUPA 4WVTA 4MU7A 5C3HA 1JD5A 4KMNA 2VM5A 3UEGA 2JK7A 4KMPA 1SDZA 3UEFA 1Q4QA 2POPB 3GTAA 1E31A 5C7DA 3M0AD 4J46A 3UIIA 4OXCA 3OZ1A 4J45A 3UEHA 5C84A 1XOXA 3UIJA 3UIKA 1I3OE 1JD4A 4LGEA 3SIQA 1XB0A 1QBHA 5C7BA 2OPZA 3UIGA 3CLXA 3SIPE 3CM2A 2QFAA 1F9XA 1G73C 5C0KA 4HY5A 3G76A 2I3HA 1TW6A 4J44A 4KJUA 4HY0A 2OPYA 1TFQA 3F7HA 5C7CA 3UEEA 1F3HA 4WVSA 4MTIA 1OY7A 4KJVA 1G3FA 3UW4A 3M1DA 4J47A 3GT9A
chains in the Genus database with same CATH superfamily
4J3YA 2RAWA 3D9UA 3D9TA 3T6PA 5C83A 4A0IA 1XB1A 1SE0A 1C9QA 3UW5A 3M0DD 3HL5A 2VSLA 5C7AA 4EC4A 3CM7A 1JD6A 4A0NA 3F7GA 1NW9A 2UVLA 5C3KA 4MTZA 3F7IA 1M4MA 3UEIA 2I3IA 2POIA 1OXNA 2QRAA 4A0JA 3UIHA 4LGUA 3UECA 3UEDA 4EB9A 4HY4A 1OXQA 2RAXA 3EYLA 4J48A 5C0LA 4WVUA 1TFTA 3MUPA 4WVTA 4MU7A 5C3HA 1JD5A 4KMNA 2VM5A 3UEGA 2JK7A 4KMPA 1SDZA 3UEFA 1Q4QA 2POPB 3GTAA 1E31A 5C7DA 3M0AD 4J46A 3UIIA 4OXCA 3OZ1A 4J45A 3UEHA 5C84A 1XOXA 3UIJA 3UIKA 1I3OE 1JD4A 4LGEA 3SIQA 1XB0A 1QBHA 5C7BA 2OPZA 3UIGA 3CLXA 3SIPE 3CM2A 2QFAA 1F9XA 1G73C 5C0KA 4HY5A 3G76A 2I3HA 1TW6A 4J44A 4KJUA 4HY0A 2OPYA 1TFQA 3F7HA 5C7CA 3UEEA 1F3HA 4WVSA 4MTIA 1OY7A 4KJVA 1G3FA 3UW4A 3M1DA 4J47A 3GT9A
chains in the Genus database with same CATH topology
4J3YA 2RAWA 3D9UA 3D9TA 3T6PA 5C83A 4A0IA 1XB1A 1SE0A 1C9QA 3UW5A 3M0DD 3HL5A 2VSLA 5C7AA 4EC4A 3CM7A 1JD6A 4A0NA 3F7GA 1NW9A 2UVLA 5C3KA 4MTZA 3F7IA 1M4MA 3UEIA 2I3IA 2POIA 1OXNA 2QRAA 4A0JA 3UIHA 4LGUA 3UECA 3UEDA 4EB9A 4HY4A 1OXQA 2RAXA 3EYLA 4J48A 5C0LA 4WVUA 1TFTA 3MUPA 4WVTA 4MU7A 5C3HA 1JD5A 4KMNA 2VM5A 3UEGA 2JK7A 4KMPA 1SDZA 3UEFA 1Q4QA 2POPB 3GTAA 1E31A 5C7DA 3M0AD 4J46A 3UIIA 4OXCA 3OZ1A 4J45A 3UEHA 5C84A 1XOXA 3UIJA 3UIKA 1I3OE 1JD4A 4LGEA 3SIQA 1XB0A 1QBHA 5C7BA 2OPZA 3UIGA 3CLXA 3SIPE 3CM2A 2QFAA 1F9XA 1G73C 5C0KA 4HY5A 3G76A 2I3HA 1TW6A 4J44A 4KJUA 4HY0A 2OPYA 1TFQA 3F7HA 5C7CA 3UEEA 1F3HA 4WVSA 4MTIA 1OY7A 4KJVA 1G3FA 3UW4A 3M1DA 4J47A 3GT9A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4J3Y A;  2RAW A;  3D9U A;  3D9T A;  3T6P A;  5C83 A;  4A0I A;  1XB1 A;  1SE0 A;  1C9Q A;  3UW5 A;  3M0D D;  3HL5 A;  2VSL A;  5C7A A;  4EC4 A;  3CM7 A;  1JD6 A;  4A0N A;  3F7G A;  1NW9 A;  2UVL A;  5C3K A;  4MTZ A;  3F7I A;  1M4M A;  3UEI A;  2I3I A;  2POI A;  1OXN A;  2QRA A;  4A0J A;  3UIH A;  4LGU A;  3UEC A;  3UED A;  4EB9 A;  4HY4 A;  1OXQ A;  2RAX A;  3EYL A;  4J48 A;  5C0L A;  4WVU A;  1TFT A;  3MUP A;  4WVT A;  4MU7 A;  5C3H A;  1JD5 A;  4KMN A;  2VM5 A;  3UEG A;  2JK7 A;  4KMP A;  1SDZ A;  3UEF A;  1Q4Q A;  2POP B;  3GTA A;  1E31 A;  5C7D A;  3M0A D;  4J46 A;  3UII A;  4OXC A;  3OZ1 A;  4J45 A;  3UEH A;  5C84 A;  1XOX A;  3UIJ A;  3UIK A;  1I3O E;  1JD4 A;  4LGE A;  3SIQ A;  1XB0 A;  1QBH A;  5C7B A;  2OPZ A;  3UIG A;  3CLX A;  3SIP E;  3CM2 A;  2QFA A;  1F9X A;  1G73 C;  5C0K A;  4HY5 A;  3G76 A;  2I3H A;  1TW6 A;  4J44 A;  4KJU A;  4HY0 A;  2OPY A;  1TFQ A;  3F7H A;  5C7C A;  3UEE A;  1F3H A;  4WVS A;  4MTI A;  1OY7 A;  4KJV A;  1G3F A;  3UW4 A;  3M1D A;  4J47 A;  3GT9 A; 
#chains in the Genus database with same CATH topology
 4J3Y A;  2RAW A;  3D9U A;  3D9T A;  3T6P A;  5C83 A;  4A0I A;  1XB1 A;  1SE0 A;  1C9Q A;  3UW5 A;  3M0D D;  3HL5 A;  2VSL A;  5C7A A;  4EC4 A;  3CM7 A;  1JD6 A;  4A0N A;  3F7G A;  1NW9 A;  2UVL A;  5C3K A;  4MTZ A;  3F7I A;  1M4M A;  3UEI A;  2I3I A;  2POI A;  1OXN A;  2QRA A;  4A0J A;  3UIH A;  4LGU A;  3UEC A;  3UED A;  4EB9 A;  4HY4 A;  1OXQ A;  2RAX A;  3EYL A;  4J48 A;  5C0L A;  4WVU A;  1TFT A;  3MUP A;  4WVT A;  4MU7 A;  5C3H A;  1JD5 A;  4KMN A;  2VM5 A;  3UEG A;  2JK7 A;  4KMP A;  1SDZ A;  3UEF A;  1Q4Q A;  2POP B;  3GTA A;  1E31 A;  5C7D A;  3M0A D;  4J46 A;  3UII A;  4OXC A;  3OZ1 A;  4J45 A;  3UEH A;  5C84 A;  1XOX A;  3UIJ A;  3UIK A;  1I3O E;  1JD4 A;  4LGE A;  3SIQ A;  1XB0 A;  1QBH A;  5C7B A;  2OPZ A;  3UIG A;  3CLX A;  3SIP E;  3CM2 A;  2QFA A;  1F9X A;  1G73 C;  5C0K A;  4HY5 A;  3G76 A;  2I3H A;  1TW6 A;  4J44 A;  4KJU A;  4HY0 A;  2OPY A;  1TFQ A;  3F7H A;  5C7C A;  3UEE A;  1F3H A;  4WVS A;  4MTI A;  1OY7 A;  4KJV A;  1G3F A;  3UW4 A;  3M1D A;  4J47 A;  3GT9 A; 
#chains in the Genus database with same CATH homology
 4J3Y A;  2RAW A;  3D9U A;  3D9T A;  3T6P A;  5C83 A;  4A0I A;  1XB1 A;  1SE0 A;  1C9Q A;  3UW5 A;  3M0D D;  3HL5 A;  2VSL A;  5C7A A;  4EC4 A;  3CM7 A;  1JD6 A;  4A0N A;  3F7G A;  1NW9 A;  2UVL A;  5C3K A;  4MTZ A;  3F7I A;  1M4M A;  3UEI A;  2I3I A;  2POI A;  1OXN A;  2QRA A;  4A0J A;  3UIH A;  4LGU A;  3UEC A;  3UED A;  4EB9 A;  4HY4 A;  1OXQ A;  2RAX A;  3EYL A;  4J48 A;  5C0L A;  4WVU A;  1TFT A;  3MUP A;  4WVT A;  4MU7 A;  5C3H A;  1JD5 A;  4KMN A;  2VM5 A;  3UEG A;  2JK7 A;  4KMP A;  1SDZ A;  3UEF A;  1Q4Q A;  2POP B;  3GTA A;  1E31 A;  5C7D A;  3M0A D;  4J46 A;  3UII A;  4OXC A;  3OZ1 A;  4J45 A;  3UEH A;  5C84 A;  1XOX A;  3UIJ A;  3UIK A;  1I3O E;  1JD4 A;  4LGE A;  3SIQ A;  1XB0 A;  1QBH A;  5C7B A;  2OPZ A;  3UIG A;  3CLX A;  3SIP E;  3CM2 A;  2QFA A;  1F9X A;  1G73 C;  5C0K A;  4HY5 A;  3G76 A;  2I3H A;  1TW6 A;  4J44 A;  4KJU A;  4HY0 A;  2OPY A;  1TFQ A;  3F7H A;  5C7C A;  3UEE A;  1F3H A;  4WVS A;  4MTI A;  1OY7 A;  4KJV A;  1G3F A;  3UW4 A;  3M1D A;  4J47 A;  3GT9 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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