4EB9A

Ciap1-bir3 in complex with a divalent smac mimetic
Total Genus 18
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
18
sequence length
102
structure length
102
Chain Sequence
SISNLSMQTHAARMRTFMYWPSSVPVQPEQLASAGFYYVGRNDDVKCFCCDGGLRCWESGDDPWVEHAKWFPRCEFLIRMKGQEFVDEIQGRYPHLLEQLLS
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Structural insight into inhibitor of apoptosis proteins recognition by a potent divalent smac-mimetic.
pubmed doi rcsb
molecule tags Apoptosis inhibitor
source organism Homo sapiens
molecule keywords Baculoviral IAP repeat-containing protein 2
total genus 18
structure length 102
sequence length 102
chains with identical sequence B, C, D
ec nomenclature ec 2.3.2.27: RING-type E3 ubiquitin transferase.
pdb deposition date 2012-03-23

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00653 BIR Inhibitor of Apoptosis domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.1170.10 Mainly Alpha Orthogonal Bundle Inhibitor Of Apoptosis Protein (2mihbC-IAP-1); Chain A Inhibitor Of Apoptosis Protein (2mihbC-IAP-1); Chain A 4eb9A00
1JD6A 4KJVA 1C9QA 2OPYA 1Q4QA 2RAXA 3D9UA 1XOXA 3F7GA 2OPZA 3UEFA 4LGUA 3UEEA 3UIGA 2I3IA 5C3HA 3F7HA 4KMNA 4J48A 4HY0A 4WVTA 3UIIA 3GTAA 4J47A 2I3HA 3UIHA 5C7BA 5C0KA 3UEGA 4WVUA 3M1DA 2VM5A 1TFTA 3UEDA 5C83A 1TW6A 4MTIA 4MTZA 1NW9A 3F7IA 4A0JA 4J44A 3HL5A 4KJUA 3UECA 4J45A 1M4MA 1I3OE 5C84A 4HY5A 1E31A 5C3KA 3UEHA 3EYLA 1TFQA 4MU7A 1JD5A 2QRAA 3SIQA 2VSLA 1XB1A 2POIA 1F3HA 3M0DD 1OXNA 3G76A 4J46A 2JK7A 3CLXA 5C0LA 2UVLA 3GT9A 3CM7A 1JD4A 3OZ1A 4A0NA 5C7AA 3CM2A 4OXCA 3UW4A 1OXQA 3SIPE 1G73C 1XB0A 4EB9A 3UW5A 1F9XA 4LGEA 4A0IA 4J3YA 3D9TA 4EC4A 5C7CA 2RAWA 3UIJA 1SE0A 2POPB 1QBHA 3M0AD 3UIKA 4HY4A 2QFAA 1OY7A 3UEIA 3MUPA 1G3FA 3T6PA 4KMPA 5C7DA 1SDZA 4WVSA
chains in the Genus database with same CATH superfamily
1JD6A 4KJVA 1C9QA 2OPYA 1Q4QA 2RAXA 3D9UA 1XOXA 3F7GA 2OPZA 3UEFA 4LGUA 3UEEA 3UIGA 2I3IA 5C3HA 3F7HA 4KMNA 4J48A 4HY0A 4WVTA 3UIIA 3GTAA 4J47A 2I3HA 3UIHA 5C7BA 5C0KA 3UEGA 4WVUA 3M1DA 2VM5A 1TFTA 3UEDA 5C83A 1TW6A 4MTIA 4MTZA 1NW9A 3F7IA 4A0JA 4J44A 3HL5A 4KJUA 3UECA 4J45A 1M4MA 1I3OE 5C84A 4HY5A 1E31A 5C3KA 3UEHA 3EYLA 1TFQA 4MU7A 1JD5A 2QRAA 3SIQA 2VSLA 1XB1A 2POIA 1F3HA 3M0DD 1OXNA 3G76A 4J46A 2JK7A 3CLXA 5C0LA 2UVLA 3GT9A 3CM7A 1JD4A 3OZ1A 4A0NA 5C7AA 3CM2A 4OXCA 3UW4A 1OXQA 3SIPE 1G73C 1XB0A 4EB9A 3UW5A 1F9XA 4LGEA 4A0IA 4J3YA 3D9TA 4EC4A 5C7CA 2RAWA 3UIJA 1SE0A 2POPB 1QBHA 3M0AD 3UIKA 4HY4A 2QFAA 1OY7A 3UEIA 3MUPA 1G3FA 3T6PA 4KMPA 5C7DA 1SDZA 4WVSA
chains in the Genus database with same CATH topology
1JD6A 4KJVA 1C9QA 2OPYA 1Q4QA 2RAXA 3D9UA 1XOXA 3F7GA 2OPZA 3UEFA 4LGUA 3UEEA 3UIGA 2I3IA 5C3HA 3F7HA 4KMNA 4J48A 4HY0A 4WVTA 3UIIA 3GTAA 4J47A 2I3HA 3UIHA 5C7BA 5C0KA 3UEGA 4WVUA 3M1DA 2VM5A 1TFTA 3UEDA 5C83A 1TW6A 4MTIA 4MTZA 1NW9A 3F7IA 4A0JA 4J44A 3HL5A 4KJUA 3UECA 4J45A 1M4MA 1I3OE 5C84A 4HY5A 1E31A 5C3KA 3UEHA 3EYLA 1TFQA 4MU7A 1JD5A 2QRAA 3SIQA 2VSLA 1XB1A 2POIA 1F3HA 3M0DD 1OXNA 3G76A 4J46A 2JK7A 3CLXA 5C0LA 2UVLA 3GT9A 3CM7A 1JD4A 3OZ1A 4A0NA 5C7AA 3CM2A 4OXCA 3UW4A 1OXQA 3SIPE 1G73C 1XB0A 4EB9A 3UW5A 1F9XA 4LGEA 4A0IA 4J3YA 3D9TA 4EC4A 5C7CA 2RAWA 3UIJA 1SE0A 2POPB 1QBHA 3M0AD 3UIKA 4HY4A 2QFAA 1OY7A 3UEIA 3MUPA 1G3FA 3T6PA 4KMPA 5C7DA 1SDZA 4WVSA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1JD6 A;  4KJV A;  1C9Q A;  2OPY A;  1Q4Q A;  2RAX A;  3D9U A;  1XOX A;  3F7G A;  2OPZ A;  3UEF A;  4LGU A;  3UEE A;  3UIG A;  2I3I A;  5C3H A;  3F7H A;  4KMN A;  4J48 A;  4HY0 A;  4WVT A;  3UII A;  3GTA A;  4J47 A;  2I3H A;  3UIH A;  5C7B A;  5C0K A;  3UEG A;  4WVU A;  3M1D A;  2VM5 A;  1TFT A;  3UED A;  5C83 A;  1TW6 A;  4MTI A;  4MTZ A;  1NW9 A;  3F7I A;  4A0J A;  4J44 A;  3HL5 A;  4KJU A;  3UEC A;  4J45 A;  1M4M A;  1I3O E;  5C84 A;  4HY5 A;  1E31 A;  5C3K A;  3UEH A;  3EYL A;  1TFQ A;  4MU7 A;  1JD5 A;  2QRA A;  3SIQ A;  2VSL A;  1XB1 A;  2POI A;  1F3H A;  3M0D D;  1OXN A;  3G76 A;  4J46 A;  2JK7 A;  3CLX A;  5C0L A;  2UVL A;  3GT9 A;  3CM7 A;  1JD4 A;  3OZ1 A;  4A0N A;  5C7A A;  3CM2 A;  4OXC A;  3UW4 A;  1OXQ A;  3SIP E;  1G73 C;  1XB0 A;  4EB9 A;  3UW5 A;  1F9X A;  4LGE A;  4A0I A;  4J3Y A;  3D9T A;  4EC4 A;  5C7C A;  2RAW A;  3UIJ A;  1SE0 A;  2POP B;  1QBH A;  3M0A D;  3UIK A;  4HY4 A;  2QFA A;  1OY7 A;  3UEI A;  3MUP A;  1G3F A;  3T6P A;  4KMP A;  5C7D A;  1SDZ A;  4WVS A; 
#chains in the Genus database with same CATH topology
 1JD6 A;  4KJV A;  1C9Q A;  2OPY A;  1Q4Q A;  2RAX A;  3D9U A;  1XOX A;  3F7G A;  2OPZ A;  3UEF A;  4LGU A;  3UEE A;  3UIG A;  2I3I A;  5C3H A;  3F7H A;  4KMN A;  4J48 A;  4HY0 A;  4WVT A;  3UII A;  3GTA A;  4J47 A;  2I3H A;  3UIH A;  5C7B A;  5C0K A;  3UEG A;  4WVU A;  3M1D A;  2VM5 A;  1TFT A;  3UED A;  5C83 A;  1TW6 A;  4MTI A;  4MTZ A;  1NW9 A;  3F7I A;  4A0J A;  4J44 A;  3HL5 A;  4KJU A;  3UEC A;  4J45 A;  1M4M A;  1I3O E;  5C84 A;  4HY5 A;  1E31 A;  5C3K A;  3UEH A;  3EYL A;  1TFQ A;  4MU7 A;  1JD5 A;  2QRA A;  3SIQ A;  2VSL A;  1XB1 A;  2POI A;  1F3H A;  3M0D D;  1OXN A;  3G76 A;  4J46 A;  2JK7 A;  3CLX A;  5C0L A;  2UVL A;  3GT9 A;  3CM7 A;  1JD4 A;  3OZ1 A;  4A0N A;  5C7A A;  3CM2 A;  4OXC A;  3UW4 A;  1OXQ A;  3SIP E;  1G73 C;  1XB0 A;  4EB9 A;  3UW5 A;  1F9X A;  4LGE A;  4A0I A;  4J3Y A;  3D9T A;  4EC4 A;  5C7C A;  2RAW A;  3UIJ A;  1SE0 A;  2POP B;  1QBH A;  3M0A D;  3UIK A;  4HY4 A;  2QFA A;  1OY7 A;  3UEI A;  3MUP A;  1G3F A;  3T6P A;  4KMP A;  5C7D A;  1SDZ A;  4WVS A; 
#chains in the Genus database with same CATH homology
 1JD6 A;  4KJV A;  1C9Q A;  2OPY A;  1Q4Q A;  2RAX A;  3D9U A;  1XOX A;  3F7G A;  2OPZ A;  3UEF A;  4LGU A;  3UEE A;  3UIG A;  2I3I A;  5C3H A;  3F7H A;  4KMN A;  4J48 A;  4HY0 A;  4WVT A;  3UII A;  3GTA A;  4J47 A;  2I3H A;  3UIH A;  5C7B A;  5C0K A;  3UEG A;  4WVU A;  3M1D A;  2VM5 A;  1TFT A;  3UED A;  5C83 A;  1TW6 A;  4MTI A;  4MTZ A;  1NW9 A;  3F7I A;  4A0J A;  4J44 A;  3HL5 A;  4KJU A;  3UEC A;  4J45 A;  1M4M A;  1I3O E;  5C84 A;  4HY5 A;  1E31 A;  5C3K A;  3UEH A;  3EYL A;  1TFQ A;  4MU7 A;  1JD5 A;  2QRA A;  3SIQ A;  2VSL A;  1XB1 A;  2POI A;  1F3H A;  3M0D D;  1OXN A;  3G76 A;  4J46 A;  2JK7 A;  3CLX A;  5C0L A;  2UVL A;  3GT9 A;  3CM7 A;  1JD4 A;  3OZ1 A;  4A0N A;  5C7A A;  3CM2 A;  4OXC A;  3UW4 A;  1OXQ A;  3SIP E;  1G73 C;  1XB0 A;  4EB9 A;  3UW5 A;  1F9X A;  4LGE A;  4A0I A;  4J3Y A;  3D9T A;  4EC4 A;  5C7C A;  2RAW A;  3UIJ A;  1SE0 A;  2POP B;  1QBH A;  3M0A D;  3UIK A;  4HY4 A;  2QFA A;  1OY7 A;  3UEI A;  3MUP A;  1G3F A;  3T6P A;  4KMP A;  5C7D A;  1SDZ A;  4WVS A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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