4IODA

Preliminary structural investigations of a malarial protein secretion system.
Total Genus 64
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
64
sequence length
147
structure length
147
Chain Sequence
GKYLNRTINILNAGKNIAKSYGHNKLKPIHILSALAKSDYGSTLFKENNVNAANLKEYIDIALEQTRAGAPLDNKSKIVNSAEVKETLALAEAAANKYKSPKVDVEHLLSGLSNDELVNEIFNEVYLTDEAIKAILKRKFEKTLVPR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural mapping of the ClpB ATPases of Plasmodium falciparum: Targeting protein folding and secretion for antimalarial drug design.
pubmed doi rcsb
molecule tags Chaperone
source organism Plasmodium falciparum
molecule keywords Malarial CLP B2 atpase/HSP101 protein
total genus 64
structure length 147
sequence length 147
chains with identical sequence B, C
ec nomenclature
pdb deposition date 2013-01-07

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF02861 Clp_N Clp amino terminal domain, pathogenicity island component
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.1780.10 Mainly Alpha Orthogonal Bundle Double Clp-N motif Clp, N-terminal domain 4iodA00
5HBNA 4UQWA 1MBVA 2Y1QA 3WDBA 1KSFX 3WDEA 5GUIA 1LZWB 3FESA 3WDCA 4HH5A 2Y1RA 1KHYA 3ZRIA 4IODA 1QVRA 3FH2A 1R6QA 1MBUA 4IRFA 1R6OA 4Y0BA 4Y0CA 1K6KA 4HH6A 3WDDA 1MG9B 1R6CX 4P15A 3ZRJA 1MBXA 1R6BX 3PXGA 2K77A
chains in the Genus database with same CATH superfamily
5HBNA 4UQWA 1MBVA 2Y1QA 3WDBA 1KSFX 3WDEA 5GUIA 1LZWB 3FESA 3WDCA 4HH5A 2Y1RA 1KHYA 3ZRIA 4IODA 1QVRA 3FH2A 1R6QA 1MBUA 4IRFA 1R6OA 4Y0BA 4Y0CA 1K6KA 4HH6A 3WDDA 1MG9B 1R6CX 4P15A 3ZRJA 1MBXA 1R6BX 3PXGA 2K77A
chains in the Genus database with same CATH topology
5HBNA 4UQWA 1MBVA 2Y1QA 3WDBA 1KSFX 3WDEA 5GUIA 1LZWB 3FESA 3WDCA 4HH5A 2Y1RA 1KHYA 3ZRIA 4IODA 1QVRA 3FH2A 1R6QA 1MBUA 4IRFA 1R6OA 4Y0BA 4Y0CA 1K6KA 4HH6A 3WDDA 1MG9B 1R6CX 4P15A 3ZRJA 1MBXA 1R6BX 3PXGA 2K77A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5HBN A;  4UQW A;  1MBV A;  2Y1Q A;  3WDB A;  1KSF X;  3WDE A;  5GUI A;  1LZW B;  3FES A;  3WDC A;  4HH5 A;  2Y1R A;  1KHY A;  3ZRI A;  4IOD A;  1QVR A;  3FH2 A;  1R6Q A;  1MBU A;  4IRF A;  1R6O A;  4Y0B A;  4Y0C A;  1K6K A;  4HH6 A;  3WDD A;  1MG9 B;  1R6C X;  4P15 A;  3ZRJ A;  1MBX A;  1R6B X;  3PXG A;  2K77 A; 
#chains in the Genus database with same CATH topology
 5HBN A;  4UQW A;  1MBV A;  2Y1Q A;  3WDB A;  1KSF X;  3WDE A;  5GUI A;  1LZW B;  3FES A;  3WDC A;  4HH5 A;  2Y1R A;  1KHY A;  3ZRI A;  4IOD A;  1QVR A;  3FH2 A;  1R6Q A;  1MBU A;  4IRF A;  1R6O A;  4Y0B A;  4Y0C A;  1K6K A;  4HH6 A;  3WDD A;  1MG9 B;  1R6C X;  4P15 A;  3ZRJ A;  1MBX A;  1R6B X;  3PXG A;  2K77 A; 
#chains in the Genus database with same CATH homology
 5HBN A;  4UQW A;  1MBV A;  2Y1Q A;  3WDB A;  1KSF X;  3WDE A;  5GUI A;  1LZW B;  3FES A;  3WDC A;  4HH5 A;  2Y1R A;  1KHY A;  3ZRI A;  4IOD A;  1QVR A;  3FH2 A;  1R6Q A;  1MBU A;  4IRF A;  1R6O A;  4Y0B A;  4Y0C A;  1K6K A;  4HH6 A;  3WDD A;  1MG9 B;  1R6C X;  4P15 A;  3ZRJ A;  1MBX A;  1R6B X;  3PXG A;  2K77 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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