4IRFA

Preliminary structural investigations of a malarial protein secretion system
Total Genus 61
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
61
sequence length
145
structure length
145
Chain Sequence
QGKYLNRTINILNAGKNIAKSYGHNKLKPIHILSALAKSDYGSTLFKENNVNAANLKEYIDIALEQTRAGAPLDNKSKIVNSAEVKETLALAEAAANKYKSPKVDVEHLLSGLSNDELVNEIFNEVYLTDEAIKAILKRKFEKTL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural mapping of the ClpB ATPases of Plasmodium falciparum: Targeting protein folding and secretion for antimalarial drug design.
pubmed doi rcsb
molecule tags Chaperone
source organism Plasmodium falciparum
molecule keywords MALARIAL CLPB2 ATPASE/HSP101 PROTEIN
total genus 61
structure length 145
sequence length 145
chains with identical sequence B
ec nomenclature
pdb deposition date 2013-01-14

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF02861 Clp_N Clp amino terminal domain, pathogenicity island component
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.1780.10 Mainly Alpha Orthogonal Bundle Double Clp-N motif Clp, N-terminal domain 4irfA00
1MBXA 1QVRA 3WDCA 3PXGA 1MG9B 3FH2A 4IODA 5GUIA 2Y1RA 1MBVA 4IRFA 2Y1QA 1R6QA 3WDBA 1MBUA 1R6CX 4Y0CA 1LZWB 3FESA 4P15A 1R6BX 3ZRIA 1KSFX 2K77A 1K6KA 1R6OA 3WDEA 5HBNA 3WDDA 4UQWA 4Y0BA 4HH5A 3ZRJA 4HH6A 1KHYA
chains in the Genus database with same CATH superfamily
1MBXA 1QVRA 3WDCA 3PXGA 1MG9B 3FH2A 4IODA 5GUIA 2Y1RA 1MBVA 4IRFA 2Y1QA 1R6QA 3WDBA 1MBUA 1R6CX 4Y0CA 1LZWB 3FESA 4P15A 1R6BX 3ZRIA 1KSFX 2K77A 1K6KA 1R6OA 3WDEA 5HBNA 3WDDA 4UQWA 4Y0BA 4HH5A 3ZRJA 4HH6A 1KHYA
chains in the Genus database with same CATH topology
1MBXA 1QVRA 3WDCA 3PXGA 1MG9B 3FH2A 4IODA 5GUIA 2Y1RA 1MBVA 4IRFA 2Y1QA 1R6QA 3WDBA 1MBUA 1R6CX 4Y0CA 1LZWB 3FESA 4P15A 1R6BX 3ZRIA 1KSFX 2K77A 1K6KA 1R6OA 3WDEA 5HBNA 3WDDA 4UQWA 4Y0BA 4HH5A 3ZRJA 4HH6A 1KHYA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1MBX A;  1QVR A;  3WDC A;  3PXG A;  1MG9 B;  3FH2 A;  4IOD A;  5GUI A;  2Y1R A;  1MBV A;  4IRF A;  2Y1Q A;  1R6Q A;  3WDB A;  1MBU A;  1R6C X;  4Y0C A;  1LZW B;  3FES A;  4P15 A;  1R6B X;  3ZRI A;  1KSF X;  2K77 A;  1K6K A;  1R6O A;  3WDE A;  5HBN A;  3WDD A;  4UQW A;  4Y0B A;  4HH5 A;  3ZRJ A;  4HH6 A;  1KHY A; 
#chains in the Genus database with same CATH topology
 1MBX A;  1QVR A;  3WDC A;  3PXG A;  1MG9 B;  3FH2 A;  4IOD A;  5GUI A;  2Y1R A;  1MBV A;  4IRF A;  2Y1Q A;  1R6Q A;  3WDB A;  1MBU A;  1R6C X;  4Y0C A;  1LZW B;  3FES A;  4P15 A;  1R6B X;  3ZRI A;  1KSF X;  2K77 A;  1K6K A;  1R6O A;  3WDE A;  5HBN A;  3WDD A;  4UQW A;  4Y0B A;  4HH5 A;  3ZRJ A;  4HH6 A;  1KHY A; 
#chains in the Genus database with same CATH homology
 1MBX A;  1QVR A;  3WDC A;  3PXG A;  1MG9 B;  3FH2 A;  4IOD A;  5GUI A;  2Y1R A;  1MBV A;  4IRF A;  2Y1Q A;  1R6Q A;  3WDB A;  1MBU A;  1R6C X;  4Y0C A;  1LZW B;  3FES A;  4P15 A;  1R6B X;  3ZRI A;  1KSF X;  2K77 A;  1K6K A;  1R6O A;  3WDE A;  5HBN A;  3WDD A;  4UQW A;  4Y0B A;  4HH5 A;  3ZRJ A;  4HH6 A;  1KHY A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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