4J3YA

Crystal structure of xiap-bir2 domain
Total Genus 20
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
20
sequence length
83
structure length
83
Chain Sequence
GTIYPRNPAMYSEEARLKSFQNWPDYAHLTPRELASAGLYYTGIGDQVQCFACGGKLKNWEPGDRAWSEHRRHFPNCFFVLGR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title The structure of XIAP BIR2: understanding the selectivity of the BIR domains.
pubmed doi rcsb
molecule tags Apoptosis
source organism Homo sapiens
molecule keywords E3 ubiquitin-protein ligase XIAP
total genus 20
structure length 83
sequence length 83
chains with identical sequence C
ec nomenclature ec 2.3.2.27: RING-type E3 ubiquitin transferase.
pdb deposition date 2013-02-06

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00653 BIR Inhibitor of Apoptosis domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.1170.10 Mainly Alpha Orthogonal Bundle Inhibitor Of Apoptosis Protein (2mihbC-IAP-1); Chain A Inhibitor Of Apoptosis Protein (2mihbC-IAP-1); Chain A 4j3yA00
4LGUA 2I3IA 5C83A 3SIQA 2VM5A 4KMPA 4A0JA 5C3KA 3UECA 1M4MA 1NW9A 4LGEA 2RAWA 2VSLA 5C7BA 5C3HA 1I3OE 4J48A 1F9XA 3T6PA 2JK7A 3M0AD 4MU7A 5C0LA 1OXQA 1OY7A 4KJVA 2UVLA 4HY5A 3UEHA 3UW4A 3UEFA 3UEIA 3MUPA 4A0IA 2POPB 5C84A 1XOXA 3F7GA 3CM2A 3G76A 4EC4A 1TFQA 2QFAA 3OZ1A 3UEDA 4KMNA 4EB9A 1SDZA 3UIGA 3CLXA 1QBHA 3UEGA 3D9UA 1G3FA 1TW6A 1OXNA 4J44A 3F7HA 3CM7A 4KJUA 3D9TA 2OPYA 3UIHA 1SE0A 3EYLA 4OXCA 5C0KA 5C7CA 4J3YA 4J45A 3UIJA 4MTZA 3UIKA 1C9QA 5C7DA 1XB0A 1JD5A 3GTAA 3M1DA 4WVTA 1TFTA 4A0NA 1JD4A 1JD6A 1G73C 3F7IA 3UIIA 3GT9A 4WVUA 3SIPE 3UW5A 1F3HA 3UEEA 1Q4QA 5C7AA 3HL5A 2POIA 4HY4A 2RAXA 4J47A 4J46A 2I3HA 3M0DD 1E31A 4HY0A 2OPZA 4MTIA 2QRAA 1XB1A 4WVSA
chains in the Genus database with same CATH superfamily
4LGUA 2I3IA 5C83A 3SIQA 2VM5A 4KMPA 4A0JA 5C3KA 3UECA 1M4MA 1NW9A 4LGEA 2RAWA 2VSLA 5C7BA 5C3HA 1I3OE 4J48A 1F9XA 3T6PA 2JK7A 3M0AD 4MU7A 5C0LA 1OXQA 1OY7A 4KJVA 2UVLA 4HY5A 3UEHA 3UW4A 3UEFA 3UEIA 3MUPA 4A0IA 2POPB 5C84A 1XOXA 3F7GA 3CM2A 3G76A 4EC4A 1TFQA 2QFAA 3OZ1A 3UEDA 4KMNA 4EB9A 1SDZA 3UIGA 3CLXA 1QBHA 3UEGA 3D9UA 1G3FA 1TW6A 1OXNA 4J44A 3F7HA 3CM7A 4KJUA 3D9TA 2OPYA 3UIHA 1SE0A 3EYLA 4OXCA 5C0KA 5C7CA 4J3YA 4J45A 3UIJA 4MTZA 3UIKA 1C9QA 5C7DA 1XB0A 1JD5A 3GTAA 3M1DA 4WVTA 1TFTA 4A0NA 1JD4A 1JD6A 1G73C 3F7IA 3UIIA 3GT9A 4WVUA 3SIPE 3UW5A 1F3HA 3UEEA 1Q4QA 5C7AA 3HL5A 2POIA 4HY4A 2RAXA 4J47A 4J46A 2I3HA 3M0DD 1E31A 4HY0A 2OPZA 4MTIA 2QRAA 1XB1A 4WVSA
chains in the Genus database with same CATH topology
4LGUA 2I3IA 5C83A 3SIQA 2VM5A 4KMPA 4A0JA 5C3KA 3UECA 1M4MA 1NW9A 4LGEA 2RAWA 2VSLA 5C7BA 5C3HA 1I3OE 4J48A 1F9XA 3T6PA 2JK7A 3M0AD 4MU7A 5C0LA 1OXQA 1OY7A 4KJVA 2UVLA 4HY5A 3UEHA 3UW4A 3UEFA 3UEIA 3MUPA 4A0IA 2POPB 5C84A 1XOXA 3F7GA 3CM2A 3G76A 4EC4A 1TFQA 2QFAA 3OZ1A 3UEDA 4KMNA 4EB9A 1SDZA 3UIGA 3CLXA 1QBHA 3UEGA 3D9UA 1G3FA 1TW6A 1OXNA 4J44A 3F7HA 3CM7A 4KJUA 3D9TA 2OPYA 3UIHA 1SE0A 3EYLA 4OXCA 5C0KA 5C7CA 4J3YA 4J45A 3UIJA 4MTZA 3UIKA 1C9QA 5C7DA 1XB0A 1JD5A 3GTAA 3M1DA 4WVTA 1TFTA 4A0NA 1JD4A 1JD6A 1G73C 3F7IA 3UIIA 3GT9A 4WVUA 3SIPE 3UW5A 1F3HA 3UEEA 1Q4QA 5C7AA 3HL5A 2POIA 4HY4A 2RAXA 4J47A 4J46A 2I3HA 3M0DD 1E31A 4HY0A 2OPZA 4MTIA 2QRAA 1XB1A 4WVSA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4LGU A;  2I3I A;  5C83 A;  3SIQ A;  2VM5 A;  4KMP A;  4A0J A;  5C3K A;  3UEC A;  1M4M A;  1NW9 A;  4LGE A;  2RAW A;  2VSL A;  5C7B A;  5C3H A;  1I3O E;  4J48 A;  1F9X A;  3T6P A;  2JK7 A;  3M0A D;  4MU7 A;  5C0L A;  1OXQ A;  1OY7 A;  4KJV A;  2UVL A;  4HY5 A;  3UEH A;  3UW4 A;  3UEF A;  3UEI A;  3MUP A;  4A0I A;  2POP B;  5C84 A;  1XOX A;  3F7G A;  3CM2 A;  3G76 A;  4EC4 A;  1TFQ A;  2QFA A;  3OZ1 A;  3UED A;  4KMN A;  4EB9 A;  1SDZ A;  3UIG A;  3CLX A;  1QBH A;  3UEG A;  3D9U A;  1G3F A;  1TW6 A;  1OXN A;  4J44 A;  3F7H A;  3CM7 A;  4KJU A;  3D9T A;  2OPY A;  3UIH A;  1SE0 A;  3EYL A;  4OXC A;  5C0K A;  5C7C A;  4J3Y A;  4J45 A;  3UIJ A;  4MTZ A;  3UIK A;  1C9Q A;  5C7D A;  1XB0 A;  1JD5 A;  3GTA A;  3M1D A;  4WVT A;  1TFT A;  4A0N A;  1JD4 A;  1JD6 A;  1G73 C;  3F7I A;  3UII A;  3GT9 A;  4WVU A;  3SIP E;  3UW5 A;  1F3H A;  3UEE A;  1Q4Q A;  5C7A A;  3HL5 A;  2POI A;  4HY4 A;  2RAX A;  4J47 A;  4J46 A;  2I3H A;  3M0D D;  1E31 A;  4HY0 A;  2OPZ A;  4MTI A;  2QRA A;  1XB1 A;  4WVS A; 
#chains in the Genus database with same CATH topology
 4LGU A;  2I3I A;  5C83 A;  3SIQ A;  2VM5 A;  4KMP A;  4A0J A;  5C3K A;  3UEC A;  1M4M A;  1NW9 A;  4LGE A;  2RAW A;  2VSL A;  5C7B A;  5C3H A;  1I3O E;  4J48 A;  1F9X A;  3T6P A;  2JK7 A;  3M0A D;  4MU7 A;  5C0L A;  1OXQ A;  1OY7 A;  4KJV A;  2UVL A;  4HY5 A;  3UEH A;  3UW4 A;  3UEF A;  3UEI A;  3MUP A;  4A0I A;  2POP B;  5C84 A;  1XOX A;  3F7G A;  3CM2 A;  3G76 A;  4EC4 A;  1TFQ A;  2QFA A;  3OZ1 A;  3UED A;  4KMN A;  4EB9 A;  1SDZ A;  3UIG A;  3CLX A;  1QBH A;  3UEG A;  3D9U A;  1G3F A;  1TW6 A;  1OXN A;  4J44 A;  3F7H A;  3CM7 A;  4KJU A;  3D9T A;  2OPY A;  3UIH A;  1SE0 A;  3EYL A;  4OXC A;  5C0K A;  5C7C A;  4J3Y A;  4J45 A;  3UIJ A;  4MTZ A;  3UIK A;  1C9Q A;  5C7D A;  1XB0 A;  1JD5 A;  3GTA A;  3M1D A;  4WVT A;  1TFT A;  4A0N A;  1JD4 A;  1JD6 A;  1G73 C;  3F7I A;  3UII A;  3GT9 A;  4WVU A;  3SIP E;  3UW5 A;  1F3H A;  3UEE A;  1Q4Q A;  5C7A A;  3HL5 A;  2POI A;  4HY4 A;  2RAX A;  4J47 A;  4J46 A;  2I3H A;  3M0D D;  1E31 A;  4HY0 A;  2OPZ A;  4MTI A;  2QRA A;  1XB1 A;  4WVS A; 
#chains in the Genus database with same CATH homology
 4LGU A;  2I3I A;  5C83 A;  3SIQ A;  2VM5 A;  4KMP A;  4A0J A;  5C3K A;  3UEC A;  1M4M A;  1NW9 A;  4LGE A;  2RAW A;  2VSL A;  5C7B A;  5C3H A;  1I3O E;  4J48 A;  1F9X A;  3T6P A;  2JK7 A;  3M0A D;  4MU7 A;  5C0L A;  1OXQ A;  1OY7 A;  4KJV A;  2UVL A;  4HY5 A;  3UEH A;  3UW4 A;  3UEF A;  3UEI A;  3MUP A;  4A0I A;  2POP B;  5C84 A;  1XOX A;  3F7G A;  3CM2 A;  3G76 A;  4EC4 A;  1TFQ A;  2QFA A;  3OZ1 A;  3UED A;  4KMN A;  4EB9 A;  1SDZ A;  3UIG A;  3CLX A;  1QBH A;  3UEG A;  3D9U A;  1G3F A;  1TW6 A;  1OXN A;  4J44 A;  3F7H A;  3CM7 A;  4KJU A;  3D9T A;  2OPY A;  3UIH A;  1SE0 A;  3EYL A;  4OXC A;  5C0K A;  5C7C A;  4J3Y A;  4J45 A;  3UIJ A;  4MTZ A;  3UIK A;  1C9Q A;  5C7D A;  1XB0 A;  1JD5 A;  3GTA A;  3M1D A;  4WVT A;  1TFT A;  4A0N A;  1JD4 A;  1JD6 A;  1G73 C;  3F7I A;  3UII A;  3GT9 A;  4WVU A;  3SIP E;  3UW5 A;  1F3H A;  3UEE A;  1Q4Q A;  5C7A A;  3HL5 A;  2POI A;  4HY4 A;  2RAX A;  4J47 A;  4J46 A;  2I3H A;  3M0D D;  1E31 A;  4HY0 A;  2OPZ A;  4MTI A;  2QRA A;  1XB1 A;  4WVS A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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