4J46A

Crystal structure of xiap-bir2 domain with avpi bound
Total Genus 21
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
21
sequence length
83
structure length
83
Chain Sequence
GTIYPRNPAMYSEEARLKSFQNWPDYAHLTPRELASAGLYYTGIGDQVQCFACGGKLKNWEPGDRAWSEHRRHFPNCFFVLGR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title The structure of XIAP BIR2: understanding the selectivity of the BIR domains.
pubmed doi rcsb
molecule tags Apoptosis
source organism Homo sapiens
molecule keywords E3 ubiquitin-protein ligase XIAP
total genus 21
structure length 83
sequence length 83
chains with identical sequence C
ec nomenclature ec 2.3.2.27: RING-type E3 ubiquitin transferase.
pdb deposition date 2013-02-06

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00653 BIR Inhibitor of Apoptosis domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.1170.10 Mainly Alpha Orthogonal Bundle Inhibitor Of Apoptosis Protein (2mihbC-IAP-1); Chain A Inhibitor Of Apoptosis Protein (2mihbC-IAP-1); Chain A 4j46A00
1M4MA 1NW9A 1TFTA 3F7IA 3MUPA 3UIKA 4A0JA 1SDZA 4LGEA 3EYLA 3UEGA 3UIGA 4WVSA 3CLXA 3UEIA 1G73C 1QBHA 5C7CA 2POIA 1Q4QA 3CM2A 2VSLA 3G76A 5C0LA 2POPB 4HY5A 2OPZA 1XOXA 3M0DD 1OXQA 4MTIA 4MU7A 4WVUA 3UEFA 1JD6A 4KJVA 4A0NA 2RAWA 3UIHA 5C0KA 3UEHA 4MTZA 4EB9A 3UEDA 5C84A 2UVLA 3GTAA 3UEEA 3UW5A 3GT9A 3UW4A 4OXCA 4J48A 4HY0A 1JD5A 4A0IA 1XB0A 3D9TA 1G3FA 4KMPA 3UIIA 5C3KA 1E31A 4HY4A 4J47A 4WVTA 5C7AA 2QFAA 3UIJA 1OXNA 5C7DA 1XB1A 1TFQA 3M0AD 4J44A 1TW6A 3HL5A 5C83A 1F3HA 2JK7A 4KMNA 4KJUA 1SE0A 3M1DA 3T6PA 3OZ1A 2I3HA 2VM5A 3F7HA 3SIQA 4J3YA 4J45A 1F9XA 5C7BA 3UECA 2I3IA 2RAXA 2QRAA 1JD4A 1C9QA 3SIPE 3D9UA 4EC4A 4J46A 3F7GA 1OY7A 5C3HA 1I3OE 4LGUA 2OPYA 3CM7A
chains in the Genus database with same CATH superfamily
1M4MA 1NW9A 1TFTA 3F7IA 3MUPA 3UIKA 4A0JA 1SDZA 4LGEA 3EYLA 3UEGA 3UIGA 4WVSA 3CLXA 3UEIA 1G73C 1QBHA 5C7CA 2POIA 1Q4QA 3CM2A 2VSLA 3G76A 5C0LA 2POPB 4HY5A 2OPZA 1XOXA 3M0DD 1OXQA 4MTIA 4MU7A 4WVUA 3UEFA 1JD6A 4KJVA 4A0NA 2RAWA 3UIHA 5C0KA 3UEHA 4MTZA 4EB9A 3UEDA 5C84A 2UVLA 3GTAA 3UEEA 3UW5A 3GT9A 3UW4A 4OXCA 4J48A 4HY0A 1JD5A 4A0IA 1XB0A 3D9TA 1G3FA 4KMPA 3UIIA 5C3KA 1E31A 4HY4A 4J47A 4WVTA 5C7AA 2QFAA 3UIJA 1OXNA 5C7DA 1XB1A 1TFQA 3M0AD 4J44A 1TW6A 3HL5A 5C83A 1F3HA 2JK7A 4KMNA 4KJUA 1SE0A 3M1DA 3T6PA 3OZ1A 2I3HA 2VM5A 3F7HA 3SIQA 4J3YA 4J45A 1F9XA 5C7BA 3UECA 2I3IA 2RAXA 2QRAA 1JD4A 1C9QA 3SIPE 3D9UA 4EC4A 4J46A 3F7GA 1OY7A 5C3HA 1I3OE 4LGUA 2OPYA 3CM7A
chains in the Genus database with same CATH topology
1M4MA 1NW9A 1TFTA 3F7IA 3MUPA 3UIKA 4A0JA 1SDZA 4LGEA 3EYLA 3UEGA 3UIGA 4WVSA 3CLXA 3UEIA 1G73C 1QBHA 5C7CA 2POIA 1Q4QA 3CM2A 2VSLA 3G76A 5C0LA 2POPB 4HY5A 2OPZA 1XOXA 3M0DD 1OXQA 4MTIA 4MU7A 4WVUA 3UEFA 1JD6A 4KJVA 4A0NA 2RAWA 3UIHA 5C0KA 3UEHA 4MTZA 4EB9A 3UEDA 5C84A 2UVLA 3GTAA 3UEEA 3UW5A 3GT9A 3UW4A 4OXCA 4J48A 4HY0A 1JD5A 4A0IA 1XB0A 3D9TA 1G3FA 4KMPA 3UIIA 5C3KA 1E31A 4HY4A 4J47A 4WVTA 5C7AA 2QFAA 3UIJA 1OXNA 5C7DA 1XB1A 1TFQA 3M0AD 4J44A 1TW6A 3HL5A 5C83A 1F3HA 2JK7A 4KMNA 4KJUA 1SE0A 3M1DA 3T6PA 3OZ1A 2I3HA 2VM5A 3F7HA 3SIQA 4J3YA 4J45A 1F9XA 5C7BA 3UECA 2I3IA 2RAXA 2QRAA 1JD4A 1C9QA 3SIPE 3D9UA 4EC4A 4J46A 3F7GA 1OY7A 5C3HA 1I3OE 4LGUA 2OPYA 3CM7A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1M4M A;  1NW9 A;  1TFT A;  3F7I A;  3MUP A;  3UIK A;  4A0J A;  1SDZ A;  4LGE A;  3EYL A;  3UEG A;  3UIG A;  4WVS A;  3CLX A;  3UEI A;  1G73 C;  1QBH A;  5C7C A;  2POI A;  1Q4Q A;  3CM2 A;  2VSL A;  3G76 A;  5C0L A;  2POP B;  4HY5 A;  2OPZ A;  1XOX A;  3M0D D;  1OXQ A;  4MTI A;  4MU7 A;  4WVU A;  3UEF A;  1JD6 A;  4KJV A;  4A0N A;  2RAW A;  3UIH A;  5C0K A;  3UEH A;  4MTZ A;  4EB9 A;  3UED A;  5C84 A;  2UVL A;  3GTA A;  3UEE A;  3UW5 A;  3GT9 A;  3UW4 A;  4OXC A;  4J48 A;  4HY0 A;  1JD5 A;  4A0I A;  1XB0 A;  3D9T A;  1G3F A;  4KMP A;  3UII A;  5C3K A;  1E31 A;  4HY4 A;  4J47 A;  4WVT A;  5C7A A;  2QFA A;  3UIJ A;  1OXN A;  5C7D A;  1XB1 A;  1TFQ A;  3M0A D;  4J44 A;  1TW6 A;  3HL5 A;  5C83 A;  1F3H A;  2JK7 A;  4KMN A;  4KJU A;  1SE0 A;  3M1D A;  3T6P A;  3OZ1 A;  2I3H A;  2VM5 A;  3F7H A;  3SIQ A;  4J3Y A;  4J45 A;  1F9X A;  5C7B A;  3UEC A;  2I3I A;  2RAX A;  2QRA A;  1JD4 A;  1C9Q A;  3SIP E;  3D9U A;  4EC4 A;  4J46 A;  3F7G A;  1OY7 A;  5C3H A;  1I3O E;  4LGU A;  2OPY A;  3CM7 A; 
#chains in the Genus database with same CATH topology
 1M4M A;  1NW9 A;  1TFT A;  3F7I A;  3MUP A;  3UIK A;  4A0J A;  1SDZ A;  4LGE A;  3EYL A;  3UEG A;  3UIG A;  4WVS A;  3CLX A;  3UEI A;  1G73 C;  1QBH A;  5C7C A;  2POI A;  1Q4Q A;  3CM2 A;  2VSL A;  3G76 A;  5C0L A;  2POP B;  4HY5 A;  2OPZ A;  1XOX A;  3M0D D;  1OXQ A;  4MTI A;  4MU7 A;  4WVU A;  3UEF A;  1JD6 A;  4KJV A;  4A0N A;  2RAW A;  3UIH A;  5C0K A;  3UEH A;  4MTZ A;  4EB9 A;  3UED A;  5C84 A;  2UVL A;  3GTA A;  3UEE A;  3UW5 A;  3GT9 A;  3UW4 A;  4OXC A;  4J48 A;  4HY0 A;  1JD5 A;  4A0I A;  1XB0 A;  3D9T A;  1G3F A;  4KMP A;  3UII A;  5C3K A;  1E31 A;  4HY4 A;  4J47 A;  4WVT A;  5C7A A;  2QFA A;  3UIJ A;  1OXN A;  5C7D A;  1XB1 A;  1TFQ A;  3M0A D;  4J44 A;  1TW6 A;  3HL5 A;  5C83 A;  1F3H A;  2JK7 A;  4KMN A;  4KJU A;  1SE0 A;  3M1D A;  3T6P A;  3OZ1 A;  2I3H A;  2VM5 A;  3F7H A;  3SIQ A;  4J3Y A;  4J45 A;  1F9X A;  5C7B A;  3UEC A;  2I3I A;  2RAX A;  2QRA A;  1JD4 A;  1C9Q A;  3SIP E;  3D9U A;  4EC4 A;  4J46 A;  3F7G A;  1OY7 A;  5C3H A;  1I3O E;  4LGU A;  2OPY A;  3CM7 A; 
#chains in the Genus database with same CATH homology
 1M4M A;  1NW9 A;  1TFT A;  3F7I A;  3MUP A;  3UIK A;  4A0J A;  1SDZ A;  4LGE A;  3EYL A;  3UEG A;  3UIG A;  4WVS A;  3CLX A;  3UEI A;  1G73 C;  1QBH A;  5C7C A;  2POI A;  1Q4Q A;  3CM2 A;  2VSL A;  3G76 A;  5C0L A;  2POP B;  4HY5 A;  2OPZ A;  1XOX A;  3M0D D;  1OXQ A;  4MTI A;  4MU7 A;  4WVU A;  3UEF A;  1JD6 A;  4KJV A;  4A0N A;  2RAW A;  3UIH A;  5C0K A;  3UEH A;  4MTZ A;  4EB9 A;  3UED A;  5C84 A;  2UVL A;  3GTA A;  3UEE A;  3UW5 A;  3GT9 A;  3UW4 A;  4OXC A;  4J48 A;  4HY0 A;  1JD5 A;  4A0I A;  1XB0 A;  3D9T A;  1G3F A;  4KMP A;  3UII A;  5C3K A;  1E31 A;  4HY4 A;  4J47 A;  4WVT A;  5C7A A;  2QFA A;  3UIJ A;  1OXN A;  5C7D A;  1XB1 A;  1TFQ A;  3M0A D;  4J44 A;  1TW6 A;  3HL5 A;  5C83 A;  1F3H A;  2JK7 A;  4KMN A;  4KJU A;  1SE0 A;  3M1D A;  3T6P A;  3OZ1 A;  2I3H A;  2VM5 A;  3F7H A;  3SIQ A;  4J3Y A;  4J45 A;  1F9X A;  5C7B A;  3UEC A;  2I3I A;  2RAX A;  2QRA A;  1JD4 A;  1C9Q A;  3SIP E;  3D9U A;  4EC4 A;  4J46 A;  3F7G A;  1OY7 A;  5C3H A;  1I3O E;  4LGU A;  2OPY A;  3CM7 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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