4LDBA

Crystal structure of ebola virus vp40 dimer
Total Genus 53
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
53
sequence length
276
structure length
266
Chain Sequence
GDTPSNPLRPIADDTIDHASHTPGSVSSAFILEAMVNVISGPKVLMKQIPIWLPLGVADQKTYSFDSTTAAIMLASYTITHFGKATNPLVRVNRLGPGIPDHPLRLLRIGNQAFLQEFVLPPVQLPQYFTFDLTALKLITQPLPAATWTDDPTGSNGALRPGISFHPKLRPILLPNKLTSPEKIQAIMTSLQDFKIVPIDPTKNIMGIEVPETLVHKLTGKKVTSKNGQPIIPVLLPKYIGLDPVAPGDLTMVITQDCDTCHSPAS
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural Rearrangement of Ebola Virus VP40 Begets Multiple Functions in the Virus Life Cycle.
pubmed doi rcsb
molecule tags Viral protein
source organism Ebola virus
molecule keywords Matrix protein VP40
total genus 53
structure length 266
sequence length 276
chains with identical sequence B, C, D
ec nomenclature
pdb deposition date 2013-06-24
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.60.510.10 Mainly Beta Sandwich EV matrix protein fold EV matrix protein 4ldbA02
2.70.20.20 Mainly Beta Distorted Sandwich Topoisomerase I; domain 3 Topoisomerase I; domain 3 4ldbA01
4LDBA 1H2DA 5B0VA 1ES6A 4LD8A 4LDMA 4LDDA 3TCQA 1H2CA
chains in the Genus database with same CATH superfamily
1CY7A 1GKUB 2GAJA 4CHTA 4HIWA 5B0VA 1CY9A 4LDMA 1CYYA 4V23A 4LP7A 4CGYA 4D4TA 2YKDA 4DDUA 4G1LA 3F1JA 1H2DA 2O54A 5D5HA 1GL9B 1CY4A 4HIUA 4LDDA 3TCQA 1CY2A 1MW9X 4HIYA 4DDVA 4G1GA 2O5EA 2O19A 1CY0A 1CY8A 2VQPA 4LD8A 3PWTA 1ECLA 2GAIA 4G1OA 1H2CA 2O59A 1MW8X 4HITA 3PX7A 4LDBA 1CY1A 4DDWA 4HI6A 1I7DA 1CY6A 1ES6A 2O5CA 4RULA 4DDTA 4HI5A 1D6MA
chains in the Genus database with same CATH topology
4HIWA 5B0VA 4LDMA 4V23A 4LP7A 4D4TA 2YKDA 4G1LA 3F1JA 1H2DA 4HIUA 4LDDA 3TCQA 4HIYA 4G1GA 2VQPA 4LD8A 4G1OA 1H2CA 4HITA 4LDBA 4HI6A 1ES6A 4HI5A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4LDB A;  1H2D A;  5B0V A;  1ES6 A;  4LD8 A;  4LDM A;  4LDD A;  3TCQ A;  1H2C A; 
#chains in the Genus database with same CATH topology
 1CY7 A;  1GKU B;  2GAJ A;  4CHT A;  4HIW A;  5B0V A;  1CY9 A;  4LDM A;  1CYY A;  4V23 A;  4LP7 A;  4CGY A;  4D4T A;  2YKD A;  4DDU A;  4G1L A;  3F1J A;  1H2D A;  2O54 A;  5D5H A;  1GL9 B;  1CY4 A;  4HIU A;  4LDD A;  3TCQ A;  1CY2 A;  1MW9 X;  4HIY A;  4DDV A;  4G1G A;  2O5E A;  2O19 A;  1CY0 A;  1CY8 A;  2VQP A;  4LD8 A;  3PWT A;  1ECL A;  2GAI A;  4G1O A;  1H2C A;  2O59 A;  1MW8 X;  4HIT A;  3PX7 A;  4LDB A;  1CY1 A;  4DDW A;  4HI6 A;  1I7D A;  1CY6 A;  1ES6 A;  2O5C A;  4RUL A;  4DDT A;  4HI5 A;  1D6M A; 
#chains in the Genus database with same CATH homology
 4HIW A;  5B0V A;  4LDM A;  4V23 A;  4LP7 A;  4D4T A;  2YKD A;  4G1L A;  3F1J A;  1H2D A;  4HIU A;  4LDD A;  3TCQ A;  4HIY A;  4G1G A;  2VQP A;  4LD8 A;  4G1O A;  1H2C A;  4HIT A;  4LDB A;  4HI6 A;  1ES6 A;  4HI5 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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