4LDBA

Crystal structure of ebola virus vp40 dimer
Total Genus 53
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
53
sequence length
276
structure length
266
Chain Sequence
GDTPSNPLRPIADDTIDHASHTPGSVSSAFILEAMVNVISGPKVLMKQIPIWLPLGVADQKTYSFDSTTAAIMLASYTITHFGKATNPLVRVNRLGPGIPDHPLRLLRIGNQAFLQEFVLPPVQLPQYFTFDLTALKLITQPLPAATWTDDPTGSNGALRPGISFHPKLRPILLPNKLTSPEKIQAIMTSLQDFKIVPIDPTKNIMGIEVPETLVHKLTGKKVTSKNGQPIIPVLLPKYIGLDPVAPGDLTMVITQDCDTCHSPAS
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural Rearrangement of Ebola Virus VP40 Begets Multiple Functions in the Virus Life Cycle.
pubmed doi rcsb
molecule keywords Matrix protein VP40
molecule tags Viral protein
source organism Ebola virus
total genus 53
structure length 266
sequence length 276
chains with identical sequence B, C, D
ec nomenclature
pdb deposition date 2013-06-24
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.60.510.10 Mainly Beta Sandwich EV matrix protein fold EV matrix protein 4ldbA02
2.70.20.20 Mainly Beta Distorted Sandwich Topoisomerase I; domain 3 Topoisomerase I; domain 3 4ldbA01
1ES6A 4LD8A 3TCQA 4LDMA 5B0VA 4LDBA 1H2DA 4LDDA 1H2CA
chains in the Genus database with same CATH superfamily
5D5HA 2VQPA 4G1LA 1I7DA 1MW9X 3TCQA 1D6MA 1ECLA 4HI5A 4HI6A 1MW8X 4LP7A 4G1OA 1GL9B 1CY1A 1ES6A 4LD8A 1CY6A 4DDTA 4DDWA 4LDMA 1H2DA 4LDBA 4CGYA 4V23A 4HIYA 1GKUB 1H2CA 2GAJA 4HIWA 2GAIA 1CY0A 3F1JA 4RULA 3PX7A 1CY2A 4HIUA 4DDUA 1CY8A 5B0VA 4CHTA 4LDDA 1CY7A 2O5EA 3PWTA 1CYYA 4G1GA 1CY4A 2YKDA 2O54A 1CY9A 2O5CA 4D4TA 2O19A 2O59A 4DDVA 4HITA
chains in the Genus database with same CATH topology
2VQPA 4G1LA 3TCQA 4HI5A 4HI6A 4LP7A 4G1OA 1ES6A 4LD8A 4LDMA 1H2DA 4LDBA 4V23A 4HIYA 1H2CA 4HIWA 3F1JA 4HIUA 5B0VA 4LDDA 4G1GA 2YKDA 4D4TA 4HITA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1ES6 A;  4LD8 A;  3TCQ A;  4LDM A;  5B0V A;  4LDB A;  1H2D A;  4LDD A;  1H2C A; 
#chains in the Genus database with same CATH topology
 5D5H A;  2VQP A;  4G1L A;  1I7D A;  1MW9 X;  3TCQ A;  1D6M A;  1ECL A;  4HI5 A;  4HI6 A;  1MW8 X;  4LP7 A;  4G1O A;  1GL9 B;  1CY1 A;  1ES6 A;  4LD8 A;  1CY6 A;  4DDT A;  4DDW A;  4LDM A;  1H2D A;  4LDB A;  4CGY A;  4V23 A;  4HIY A;  1GKU B;  1H2C A;  2GAJ A;  4HIW A;  2GAI A;  1CY0 A;  3F1J A;  4RUL A;  3PX7 A;  1CY2 A;  4HIU A;  4DDU A;  1CY8 A;  5B0V A;  4CHT A;  4LDD A;  1CY7 A;  2O5E A;  3PWT A;  1CYY A;  4G1G A;  1CY4 A;  2YKD A;  2O54 A;  1CY9 A;  2O5C A;  4D4T A;  2O19 A;  2O59 A;  4DDV A;  4HIT A; 
#chains in the Genus database with same CATH homology
 2VQP A;  4G1L A;  3TCQ A;  4HI5 A;  4HI6 A;  4LP7 A;  4G1O A;  1ES6 A;  4LD8 A;  4LDM A;  1H2D A;  4LDB A;  4V23 A;  4HIY A;  1H2C A;  4HIW A;  3F1J A;  4HIU A;  5B0V A;  4LDD A;  4G1G A;  2YKD A;  4D4T A;  4HIT A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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