4LDDA

Crystal structure of ebola virus vp40 hexamer
Total Genus 27
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
27
sequence length
144
structure length
137
Chain Sequence
DTPSNPLRPIADDTIDHASHTPGSVSSAFILEAMVNVISGPLMKQIPIWLPLGVADQKTYSFDSTTAAIMLASYTITHFGNPLVRVNRLGPGIPDHPLRLLRIGNQAFLQEFVLPPLPQYFTFDLTALKLITQPLPA
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural Rearrangement of Ebola Virus VP40 Begets Multiple Functions in the Virus Life Cycle.
pubmed doi rcsb
molecule tags Viral protein
source organism Ebola virus
molecule keywords Matrix protein VP40
total genus 27
structure length 137
sequence length 144
chains with identical sequence B, C
ec nomenclature
pdb deposition date 2013-06-24
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.70.20.20 Mainly Beta Distorted Sandwich Topoisomerase I; domain 3 Topoisomerase I; domain 3 4lddA00
1ES6A 4LDDA 1H2DA 3TCQA 4LDMA 1H2CA 5B0VA 4LD8A 4LDBA
chains in the Genus database with same CATH superfamily
1CY2A 1CY6A 1MW9X 2YKDA 4HIWA 4RULA 1ECLA 4HIYA 2O5CA 2GAIA 4G1LA 1H2DA 4G1GA 2O5EA 2O54A 1CY9A 1CY8A 1MW8X 1CY7A 1CYYA 4LP7A 4HI5A 5B0VA 4CGYA 4CHTA 4G1OA 4LDBA 3F1JA 2VQPA 4HIUA 1CY1A 4LDDA 4V23A 2O59A 3TCQA 1D6MA 4HI6A 4LDMA 4D4TA 3PX7A 5D5HA 1ES6A 4HITA 1I7DA 1CY4A 1CY0A 1H2CA 2GAJA 2O19A 3PWTA 4LD8A
chains in the Genus database with same CATH topology
2YKDA 4HIWA 4HIYA 4G1LA 1H2DA 4G1GA 4LP7A 5B0VA 4HI5A 4G1OA 4LDBA 4V23A 2VQPA 4HIUA 4LDDA 3F1JA 3TCQA 4LDMA 4HI6A 4D4TA 1ES6A 4HITA 1H2CA 4LD8A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1ES6 A;  4LDD A;  1H2D A;  3TCQ A;  4LDM A;  1H2C A;  5B0V A;  4LD8 A;  4LDB A; 
#chains in the Genus database with same CATH topology
 1CY2 A;  1CY6 A;  1MW9 X;  2YKD A;  4HIW A;  4RUL A;  1ECL A;  4HIY A;  2O5C A;  2GAI A;  4G1L A;  1H2D A;  4G1G A;  2O5E A;  2O54 A;  1CY9 A;  1CY8 A;  1MW8 X;  1CY7 A;  1CYY A;  4LP7 A;  4HI5 A;  5B0V A;  4CGY A;  4CHT A;  4G1O A;  4LDB A;  3F1J A;  2VQP A;  4HIU A;  1CY1 A;  4LDD A;  4V23 A;  2O59 A;  3TCQ A;  1D6M A;  4HI6 A;  4LDM A;  4D4T A;  3PX7 A;  5D5H A;  1ES6 A;  4HIT A;  1I7D A;  1CY4 A;  1CY0 A;  1H2C A;  2GAJ A;  2O19 A;  3PWT A;  4LD8 A; 
#chains in the Genus database with same CATH homology
 2YKD A;  4HIW A;  4HIY A;  4G1L A;  1H2D A;  4G1G A;  4LP7 A;  5B0V A;  4HI5 A;  4G1O A;  4LDB A;  4V23 A;  2VQP A;  4HIU A;  4LDD A;  3F1J A;  3TCQ A;  4LDM A;  4HI6 A;  4D4T A;  1ES6 A;  4HIT A;  1H2C A;  4LD8 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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