4EB9A

Ciap1-bir3 in complex with a divalent smac mimetic
Total Genus 18
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
18
sequence length
102
structure length
102
Chain Sequence
SISNLSMQTHAARMRTFMYWPSSVPVQPEQLASAGFYYVGRNDDVKCFCCDGGLRCWESGDDPWVEHAKWFPRCEFLIRMKGQEFVDEIQGRYPHLLEQLLS
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Structural insight into inhibitor of apoptosis proteins recognition by a potent divalent smac-mimetic.
pubmed doi rcsb
molecule tags Apoptosis inhibitor
source organism Homo sapiens
molecule keywords Baculoviral IAP repeat-containing protein 2
total genus 18
structure length 102
sequence length 102
chains with identical sequence B, C, D
ec nomenclature ec 2.3.2.27: RING-type E3 ubiquitin transferase.
pdb deposition date 2012-03-23

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00653 BIR Inhibitor of Apoptosis domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.1170.10 Mainly Alpha Orthogonal Bundle Inhibitor Of Apoptosis Protein (2mihbC-IAP-1); Chain A Inhibitor Of Apoptosis Protein (2mihbC-IAP-1); Chain A 4eb9A00
4J44A 5C83A 1OXQA 4WVUA 4WVTA 1SE0A 3GT9A 3CLXA 1G3FA 3UEFA 3UEIA 1QBHA 4J3YA 3EYLA 3SIQA 4HY4A 1JD4A 2I3HA 1TFQA 3UEHA 4WVSA 5C84A 1JD6A 5C0KA 3UIIA 1M4MA 1OXNA 1SDZA 2RAWA 4MTIA 2I3IA 3UEEA 2UVLA 2RAXA 3UW5A 1XB0A 1Q4QA 1F3HA 3F7HA 5C0LA 2VM5A 1OY7A 4HY5A 3GTAA 5C3KA 2JK7A 3OZ1A 5C7BA 3F7GA 3UIJA 3G76A 3UEGA 2POPB 4EB9A 3HL5A 3F7IA 3MUPA 4J46A 1XB1A 3UW4A 1TFTA 4KMNA 2OPZA 4A0JA 2POIA 5C7CA 5C3HA 4LGEA 3CM2A 4J47A 5C7AA 3M0DD 3UECA 1NW9A 2QFAA 2OPYA 3SIPE 3UIGA 4MTZA 4A0NA 1G73C 1C9QA 2VSLA 3M0AD 2QRAA 1F9XA 3CM7A 4KMPA 3D9UA 3UEDA 1XOXA 4A0IA 4OXCA 3T6PA 4EC4A 4KJVA 3D9TA 4J48A 4HY0A 1E31A 1I3OE 1TW6A 4MU7A 4KJUA 1JD5A 3UIHA 4J45A 4LGUA 3UIKA 5C7DA 3M1DA
chains in the Genus database with same CATH superfamily
4J44A 5C83A 1OXQA 4WVUA 4WVTA 1SE0A 3GT9A 3CLXA 1G3FA 3UEFA 3UEIA 1QBHA 4J3YA 3EYLA 3SIQA 4HY4A 1JD4A 2I3HA 1TFQA 3UEHA 4WVSA 5C84A 1JD6A 5C0KA 3UIIA 1M4MA 1OXNA 1SDZA 2RAWA 4MTIA 2I3IA 3UEEA 2UVLA 2RAXA 3UW5A 1XB0A 1Q4QA 1F3HA 3F7HA 5C0LA 2VM5A 1OY7A 4HY5A 3GTAA 5C3KA 2JK7A 3OZ1A 5C7BA 3F7GA 3UIJA 3G76A 3UEGA 2POPB 4EB9A 3HL5A 3F7IA 3MUPA 4J46A 1XB1A 3UW4A 1TFTA 4KMNA 2OPZA 4A0JA 2POIA 5C7CA 5C3HA 4LGEA 3CM2A 4J47A 5C7AA 3M0DD 3UECA 1NW9A 2QFAA 2OPYA 3SIPE 3UIGA 4MTZA 4A0NA 1G73C 1C9QA 2VSLA 3M0AD 2QRAA 1F9XA 3CM7A 4KMPA 3D9UA 3UEDA 1XOXA 4A0IA 4OXCA 3T6PA 4EC4A 4KJVA 3D9TA 4J48A 4HY0A 1E31A 1I3OE 1TW6A 4MU7A 4KJUA 1JD5A 3UIHA 4J45A 4LGUA 3UIKA 5C7DA 3M1DA
chains in the Genus database with same CATH topology
4J44A 5C83A 1OXQA 4WVUA 4WVTA 1SE0A 3GT9A 3CLXA 1G3FA 3UEFA 3UEIA 1QBHA 4J3YA 3EYLA 3SIQA 4HY4A 1JD4A 2I3HA 1TFQA 3UEHA 4WVSA 5C84A 1JD6A 5C0KA 3UIIA 1M4MA 1OXNA 1SDZA 2RAWA 4MTIA 2I3IA 3UEEA 2UVLA 2RAXA 3UW5A 1XB0A 1Q4QA 1F3HA 3F7HA 5C0LA 2VM5A 1OY7A 4HY5A 3GTAA 5C3KA 2JK7A 3OZ1A 5C7BA 3F7GA 3UIJA 3G76A 3UEGA 2POPB 4EB9A 3HL5A 3F7IA 3MUPA 4J46A 1XB1A 3UW4A 1TFTA 4KMNA 2OPZA 4A0JA 2POIA 5C7CA 5C3HA 4LGEA 3CM2A 4J47A 5C7AA 3M0DD 3UECA 1NW9A 2QFAA 2OPYA 3SIPE 3UIGA 4MTZA 4A0NA 1G73C 1C9QA 2VSLA 3M0AD 2QRAA 1F9XA 3CM7A 4KMPA 3D9UA 3UEDA 1XOXA 4A0IA 4OXCA 3T6PA 4EC4A 4KJVA 3D9TA 4J48A 4HY0A 1E31A 1I3OE 1TW6A 4MU7A 4KJUA 1JD5A 3UIHA 4J45A 4LGUA 3UIKA 5C7DA 3M1DA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4J44 A;  5C83 A;  1OXQ A;  4WVU A;  4WVT A;  1SE0 A;  3GT9 A;  3CLX A;  1G3F A;  3UEF A;  3UEI A;  1QBH A;  4J3Y A;  3EYL A;  3SIQ A;  4HY4 A;  1JD4 A;  2I3H A;  1TFQ A;  3UEH A;  4WVS A;  5C84 A;  1JD6 A;  5C0K A;  3UII A;  1M4M A;  1OXN A;  1SDZ A;  2RAW A;  4MTI A;  2I3I A;  3UEE A;  2UVL A;  2RAX A;  3UW5 A;  1XB0 A;  1Q4Q A;  1F3H A;  3F7H A;  5C0L A;  2VM5 A;  1OY7 A;  4HY5 A;  3GTA A;  5C3K A;  2JK7 A;  3OZ1 A;  5C7B A;  3F7G A;  3UIJ A;  3G76 A;  3UEG A;  2POP B;  4EB9 A;  3HL5 A;  3F7I A;  3MUP A;  4J46 A;  1XB1 A;  3UW4 A;  1TFT A;  4KMN A;  2OPZ A;  4A0J A;  2POI A;  5C7C A;  5C3H A;  4LGE A;  3CM2 A;  4J47 A;  5C7A A;  3M0D D;  3UEC A;  1NW9 A;  2QFA A;  2OPY A;  3SIP E;  3UIG A;  4MTZ A;  4A0N A;  1G73 C;  1C9Q A;  2VSL A;  3M0A D;  2QRA A;  1F9X A;  3CM7 A;  4KMP A;  3D9U A;  3UED A;  1XOX A;  4A0I A;  4OXC A;  3T6P A;  4EC4 A;  4KJV A;  3D9T A;  4J48 A;  4HY0 A;  1E31 A;  1I3O E;  1TW6 A;  4MU7 A;  4KJU A;  1JD5 A;  3UIH A;  4J45 A;  4LGU A;  3UIK A;  5C7D A;  3M1D A; 
#chains in the Genus database with same CATH topology
 4J44 A;  5C83 A;  1OXQ A;  4WVU A;  4WVT A;  1SE0 A;  3GT9 A;  3CLX A;  1G3F A;  3UEF A;  3UEI A;  1QBH A;  4J3Y A;  3EYL A;  3SIQ A;  4HY4 A;  1JD4 A;  2I3H A;  1TFQ A;  3UEH A;  4WVS A;  5C84 A;  1JD6 A;  5C0K A;  3UII A;  1M4M A;  1OXN A;  1SDZ A;  2RAW A;  4MTI A;  2I3I A;  3UEE A;  2UVL A;  2RAX A;  3UW5 A;  1XB0 A;  1Q4Q A;  1F3H A;  3F7H A;  5C0L A;  2VM5 A;  1OY7 A;  4HY5 A;  3GTA A;  5C3K A;  2JK7 A;  3OZ1 A;  5C7B A;  3F7G A;  3UIJ A;  3G76 A;  3UEG A;  2POP B;  4EB9 A;  3HL5 A;  3F7I A;  3MUP A;  4J46 A;  1XB1 A;  3UW4 A;  1TFT A;  4KMN A;  2OPZ A;  4A0J A;  2POI A;  5C7C A;  5C3H A;  4LGE A;  3CM2 A;  4J47 A;  5C7A A;  3M0D D;  3UEC A;  1NW9 A;  2QFA A;  2OPY A;  3SIP E;  3UIG A;  4MTZ A;  4A0N A;  1G73 C;  1C9Q A;  2VSL A;  3M0A D;  2QRA A;  1F9X A;  3CM7 A;  4KMP A;  3D9U A;  3UED A;  1XOX A;  4A0I A;  4OXC A;  3T6P A;  4EC4 A;  4KJV A;  3D9T A;  4J48 A;  4HY0 A;  1E31 A;  1I3O E;  1TW6 A;  4MU7 A;  4KJU A;  1JD5 A;  3UIH A;  4J45 A;  4LGU A;  3UIK A;  5C7D A;  3M1D A; 
#chains in the Genus database with same CATH homology
 4J44 A;  5C83 A;  1OXQ A;  4WVU A;  4WVT A;  1SE0 A;  3GT9 A;  3CLX A;  1G3F A;  3UEF A;  3UEI A;  1QBH A;  4J3Y A;  3EYL A;  3SIQ A;  4HY4 A;  1JD4 A;  2I3H A;  1TFQ A;  3UEH A;  4WVS A;  5C84 A;  1JD6 A;  5C0K A;  3UII A;  1M4M A;  1OXN A;  1SDZ A;  2RAW A;  4MTI A;  2I3I A;  3UEE A;  2UVL A;  2RAX A;  3UW5 A;  1XB0 A;  1Q4Q A;  1F3H A;  3F7H A;  5C0L A;  2VM5 A;  1OY7 A;  4HY5 A;  3GTA A;  5C3K A;  2JK7 A;  3OZ1 A;  5C7B A;  3F7G A;  3UIJ A;  3G76 A;  3UEG A;  2POP B;  4EB9 A;  3HL5 A;  3F7I A;  3MUP A;  4J46 A;  1XB1 A;  3UW4 A;  1TFT A;  4KMN A;  2OPZ A;  4A0J A;  2POI A;  5C7C A;  5C3H A;  4LGE A;  3CM2 A;  4J47 A;  5C7A A;  3M0D D;  3UEC A;  1NW9 A;  2QFA A;  2OPY A;  3SIP E;  3UIG A;  4MTZ A;  4A0N A;  1G73 C;  1C9Q A;  2VSL A;  3M0A D;  2QRA A;  1F9X A;  3CM7 A;  4KMP A;  3D9U A;  3UED A;  1XOX A;  4A0I A;  4OXC A;  3T6P A;  4EC4 A;  4KJV A;  3D9T A;  4J48 A;  4HY0 A;  1E31 A;  1I3O E;  1TW6 A;  4MU7 A;  4KJU A;  1JD5 A;  3UIH A;  4J45 A;  4LGU A;  3UIK A;  5C7D A;  3M1D A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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