4EC4A

Xiap-bir3 in complex with a potent divalent smac mimetic
Total Genus 32
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
32
sequence length
109
structure length
109
Chain Sequence
SDRNFPNSTNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Structural insight into inhibitor of apoptosis proteins recognition by a potent divalent smac-mimetic.
pubmed doi rcsb
molecule tags Apoptosis inhibitor
source organism Homo sapiens
molecule keywords Baculoviral IAP repeat-containing protein 4
total genus 32
structure length 109
sequence length 109
chains with identical sequence B, C, D, E, F, G, J, K, L
ec nomenclature ec 2.3.2.27: RING-type E3 ubiquitin transferase.
pdb deposition date 2012-03-26

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00653 BIR Inhibitor of Apoptosis domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.1170.10 Mainly Alpha Orthogonal Bundle Inhibitor Of Apoptosis Protein (2mihbC-IAP-1); Chain A Inhibitor Of Apoptosis Protein (2mihbC-IAP-1); Chain A 4ec4A00
2POPB 4EC4A 2QRAA 3CLXA 5C0LA 1XB1A 3UIIA 4OXCA 1NW9A 3T6PA 1I3OE 1SDZA 1M4MA 3UEIA 3UEGA 4J48A 3UIKA 5C3HA 4WVSA 2OPZA 3SIPE 4A0IA 4KMPA 3SIQA 1XOXA 4J44A 3UW5A 3UEEA 3CM2A 4A0JA 1TW6A 3D9TA 4MTIA 5C3KA 1XB0A 5C7AA 1OXNA 3MUPA 5C0KA 1JD6A 3UW4A 3F7GA 1OXQA 2UVLA 4HY5A 3D9UA 1QBHA 4HY4A 1JD4A 1Q4QA 4LGUA 3OZ1A 2VSLA 2RAWA 4J45A 3M0DD 3EYLA 2POIA 4EB9A 4WVUA 2JK7A 4MTZA 4WVTA 1F9XA 1TFTA 2VM5A 4A0NA 2RAXA 3GTAA 4LGEA 3M1DA 3HL5A 4KJUA 3F7IA 5C83A 2QFAA 3G76A 3M0AD 1G3FA 1TFQA 5C84A 3UIGA 2OPYA 5C7DA 1C9QA 3GT9A 4J47A 2I3HA 1E31A 3UIJA 2I3IA 4J46A 1SE0A 3UEDA 5C7CA 4KMNA 4HY0A 3UEHA 4KJVA 1G73C 1JD5A 5C7BA 4MU7A 4J3YA 1F3HA 3UIHA 3UECA 1OY7A 3UEFA 3CM7A 3F7HA
chains in the Genus database with same CATH superfamily
2POPB 4EC4A 2QRAA 3CLXA 5C0LA 1XB1A 3UIIA 4OXCA 1NW9A 3T6PA 1I3OE 1SDZA 1M4MA 3UEIA 3UEGA 4J48A 3UIKA 5C3HA 4WVSA 2OPZA 3SIPE 4A0IA 4KMPA 3SIQA 1XOXA 4J44A 3UW5A 3UEEA 3CM2A 4A0JA 1TW6A 3D9TA 4MTIA 5C3KA 1XB0A 5C7AA 1OXNA 3MUPA 5C0KA 1JD6A 3UW4A 3F7GA 1OXQA 2UVLA 4HY5A 3D9UA 1QBHA 4HY4A 1JD4A 1Q4QA 4LGUA 3OZ1A 2VSLA 2RAWA 4J45A 3M0DD 3EYLA 2POIA 4EB9A 4WVUA 2JK7A 4MTZA 4WVTA 1F9XA 1TFTA 2VM5A 4A0NA 2RAXA 3GTAA 4LGEA 3M1DA 3HL5A 4KJUA 3F7IA 5C83A 2QFAA 3G76A 3M0AD 1G3FA 1TFQA 5C84A 3UIGA 2OPYA 5C7DA 1C9QA 3GT9A 4J47A 2I3HA 1E31A 3UIJA 2I3IA 4J46A 1SE0A 3UEDA 5C7CA 4KMNA 4HY0A 3UEHA 4KJVA 1G73C 1JD5A 5C7BA 4MU7A 4J3YA 1F3HA 3UIHA 3UECA 1OY7A 3UEFA 3CM7A 3F7HA
chains in the Genus database with same CATH topology
2POPB 4EC4A 2QRAA 3CLXA 5C0LA 1XB1A 3UIIA 4OXCA 1NW9A 3T6PA 1I3OE 1SDZA 1M4MA 3UEIA 3UEGA 4J48A 3UIKA 5C3HA 4WVSA 2OPZA 3SIPE 4A0IA 4KMPA 3SIQA 1XOXA 4J44A 3UW5A 3UEEA 3CM2A 4A0JA 1TW6A 3D9TA 4MTIA 5C3KA 1XB0A 5C7AA 1OXNA 3MUPA 5C0KA 1JD6A 3UW4A 3F7GA 1OXQA 2UVLA 4HY5A 3D9UA 1QBHA 4HY4A 1JD4A 1Q4QA 4LGUA 3OZ1A 2VSLA 2RAWA 4J45A 3M0DD 3EYLA 2POIA 4EB9A 4WVUA 2JK7A 4MTZA 4WVTA 1F9XA 1TFTA 2VM5A 4A0NA 2RAXA 3GTAA 4LGEA 3M1DA 3HL5A 4KJUA 3F7IA 5C83A 2QFAA 3G76A 3M0AD 1G3FA 1TFQA 5C84A 3UIGA 2OPYA 5C7DA 1C9QA 3GT9A 4J47A 2I3HA 1E31A 3UIJA 2I3IA 4J46A 1SE0A 3UEDA 5C7CA 4KMNA 4HY0A 3UEHA 4KJVA 1G73C 1JD5A 5C7BA 4MU7A 4J3YA 1F3HA 3UIHA 3UECA 1OY7A 3UEFA 3CM7A 3F7HA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2POP B;  4EC4 A;  2QRA A;  3CLX A;  5C0L A;  1XB1 A;  3UII A;  4OXC A;  1NW9 A;  3T6P A;  1I3O E;  1SDZ A;  1M4M A;  3UEI A;  3UEG A;  4J48 A;  3UIK A;  5C3H A;  4WVS A;  2OPZ A;  3SIP E;  4A0I A;  4KMP A;  3SIQ A;  1XOX A;  4J44 A;  3UW5 A;  3UEE A;  3CM2 A;  4A0J A;  1TW6 A;  3D9T A;  4MTI A;  5C3K A;  1XB0 A;  5C7A A;  1OXN A;  3MUP A;  5C0K A;  1JD6 A;  3UW4 A;  3F7G A;  1OXQ A;  2UVL A;  4HY5 A;  3D9U A;  1QBH A;  4HY4 A;  1JD4 A;  1Q4Q A;  4LGU A;  3OZ1 A;  2VSL A;  2RAW A;  4J45 A;  3M0D D;  3EYL A;  2POI A;  4EB9 A;  4WVU A;  2JK7 A;  4MTZ A;  4WVT A;  1F9X A;  1TFT A;  2VM5 A;  4A0N A;  2RAX A;  3GTA A;  4LGE A;  3M1D A;  3HL5 A;  4KJU A;  3F7I A;  5C83 A;  2QFA A;  3G76 A;  3M0A D;  1G3F A;  1TFQ A;  5C84 A;  3UIG A;  2OPY A;  5C7D A;  1C9Q A;  3GT9 A;  4J47 A;  2I3H A;  1E31 A;  3UIJ A;  2I3I A;  4J46 A;  1SE0 A;  3UED A;  5C7C A;  4KMN A;  4HY0 A;  3UEH A;  4KJV A;  1G73 C;  1JD5 A;  5C7B A;  4MU7 A;  4J3Y A;  1F3H A;  3UIH A;  3UEC A;  1OY7 A;  3UEF A;  3CM7 A;  3F7H A; 
#chains in the Genus database with same CATH topology
 2POP B;  4EC4 A;  2QRA A;  3CLX A;  5C0L A;  1XB1 A;  3UII A;  4OXC A;  1NW9 A;  3T6P A;  1I3O E;  1SDZ A;  1M4M A;  3UEI A;  3UEG A;  4J48 A;  3UIK A;  5C3H A;  4WVS A;  2OPZ A;  3SIP E;  4A0I A;  4KMP A;  3SIQ A;  1XOX A;  4J44 A;  3UW5 A;  3UEE A;  3CM2 A;  4A0J A;  1TW6 A;  3D9T A;  4MTI A;  5C3K A;  1XB0 A;  5C7A A;  1OXN A;  3MUP A;  5C0K A;  1JD6 A;  3UW4 A;  3F7G A;  1OXQ A;  2UVL A;  4HY5 A;  3D9U A;  1QBH A;  4HY4 A;  1JD4 A;  1Q4Q A;  4LGU A;  3OZ1 A;  2VSL A;  2RAW A;  4J45 A;  3M0D D;  3EYL A;  2POI A;  4EB9 A;  4WVU A;  2JK7 A;  4MTZ A;  4WVT A;  1F9X A;  1TFT A;  2VM5 A;  4A0N A;  2RAX A;  3GTA A;  4LGE A;  3M1D A;  3HL5 A;  4KJU A;  3F7I A;  5C83 A;  2QFA A;  3G76 A;  3M0A D;  1G3F A;  1TFQ A;  5C84 A;  3UIG A;  2OPY A;  5C7D A;  1C9Q A;  3GT9 A;  4J47 A;  2I3H A;  1E31 A;  3UIJ A;  2I3I A;  4J46 A;  1SE0 A;  3UED A;  5C7C A;  4KMN A;  4HY0 A;  3UEH A;  4KJV A;  1G73 C;  1JD5 A;  5C7B A;  4MU7 A;  4J3Y A;  1F3H A;  3UIH A;  3UEC A;  1OY7 A;  3UEF A;  3CM7 A;  3F7H A; 
#chains in the Genus database with same CATH homology
 2POP B;  4EC4 A;  2QRA A;  3CLX A;  5C0L A;  1XB1 A;  3UII A;  4OXC A;  1NW9 A;  3T6P A;  1I3O E;  1SDZ A;  1M4M A;  3UEI A;  3UEG A;  4J48 A;  3UIK A;  5C3H A;  4WVS A;  2OPZ A;  3SIP E;  4A0I A;  4KMP A;  3SIQ A;  1XOX A;  4J44 A;  3UW5 A;  3UEE A;  3CM2 A;  4A0J A;  1TW6 A;  3D9T A;  4MTI A;  5C3K A;  1XB0 A;  5C7A A;  1OXN A;  3MUP A;  5C0K A;  1JD6 A;  3UW4 A;  3F7G A;  1OXQ A;  2UVL A;  4HY5 A;  3D9U A;  1QBH A;  4HY4 A;  1JD4 A;  1Q4Q A;  4LGU A;  3OZ1 A;  2VSL A;  2RAW A;  4J45 A;  3M0D D;  3EYL A;  2POI A;  4EB9 A;  4WVU A;  2JK7 A;  4MTZ A;  4WVT A;  1F9X A;  1TFT A;  2VM5 A;  4A0N A;  2RAX A;  3GTA A;  4LGE A;  3M1D A;  3HL5 A;  4KJU A;  3F7I A;  5C83 A;  2QFA A;  3G76 A;  3M0A D;  1G3F A;  1TFQ A;  5C84 A;  3UIG A;  2OPY A;  5C7D A;  1C9Q A;  3GT9 A;  4J47 A;  2I3H A;  1E31 A;  3UIJ A;  2I3I A;  4J46 A;  1SE0 A;  3UED A;  5C7C A;  4KMN A;  4HY0 A;  3UEH A;  4KJV A;  1G73 C;  1JD5 A;  5C7B A;  4MU7 A;  4J3Y A;  1F3H A;  3UIH A;  3UEC A;  1OY7 A;  3UEF A;  3CM7 A;  3F7H A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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