4J44A

Crystal structure of xiap-bir2 domain with aiav bound
Total Genus 21
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
21
sequence length
83
structure length
83
Chain Sequence
GTIYPRNPAMYSEEARLKSFQNWPDYAHLTPRELASAGLYYTGIGDQVQCFACGGKLKNWEPGDRAWSEHRRHFPNCFFVLGR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title The structure of XIAP BIR2: understanding the selectivity of the BIR domains.
pubmed doi rcsb
molecule tags Apoptosis
source organism Homo sapiens
molecule keywords E3 ubiquitin-protein ligase XIAP
total genus 21
structure length 83
sequence length 83
chains with identical sequence C
ec nomenclature ec 2.3.2.27: RING-type E3 ubiquitin transferase.
pdb deposition date 2013-02-06

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00653 BIR Inhibitor of Apoptosis domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.1170.10 Mainly Alpha Orthogonal Bundle Inhibitor Of Apoptosis Protein (2mihbC-IAP-1); Chain A Inhibitor Of Apoptosis Protein (2mihbC-IAP-1); Chain A 4j44A00
2JK7A 4J48A 5C3HA 3UEGA 5C3KA 5C7AA 4HY0A 4EC4A 1XB0A 1SE0A 1OY7A 4LGUA 3CM7A 1JD6A 4A0IA 3UIIA 4WVTA 1C9QA 5C7DA 3GTAA 5C7CA 4EB9A 1NW9A 2UVLA 4A0JA 4J45A 1TFTA 3M0AD 3T6PA 3UEIA 5C7BA 3UIGA 3UIJA 1XB1A 2VM5A 4MTIA 4MU7A 2QRAA 3CLXA 4WVSA 3UEFA 5C0LA 4J47A 3UEDA 3HL5A 2VSLA 3GT9A 4MTZA 1F9XA 4J3YA 4WVUA 1I3OE 3F7HA 3M0DD 3UEHA 3M1DA 4HY4A 2POIA 3CM2A 2OPZA 3MUPA 1QBHA 5C84A 3UEEA 3UIKA 4J44A 2RAWA 1G3FA 3UECA 1G73C 4KMPA 1JD5A 1OXNA 2RAXA 3UW5A 3G76A 1XOXA 3SIQA 3OZ1A 3D9UA 1OXQA 1JD4A 4A0NA 2QFAA 4KJVA 1Q4QA 2I3IA 3F7GA 1SDZA 1F3HA 4HY5A 1TW6A 2POPB 4J46A 4KMNA 4LGEA 3UW4A 3UIHA 4KJUA 1E31A 3D9TA 4OXCA 5C0KA 5C83A 2OPYA 3F7IA 3EYLA 1M4MA 2I3HA 3SIPE 1TFQA
chains in the Genus database with same CATH superfamily
2JK7A 4J48A 5C3HA 3UEGA 5C3KA 5C7AA 4HY0A 4EC4A 1XB0A 1SE0A 1OY7A 4LGUA 3CM7A 1JD6A 4A0IA 3UIIA 4WVTA 1C9QA 5C7DA 3GTAA 5C7CA 4EB9A 1NW9A 2UVLA 4A0JA 4J45A 1TFTA 3M0AD 3T6PA 3UEIA 5C7BA 3UIGA 3UIJA 1XB1A 2VM5A 4MTIA 4MU7A 2QRAA 3CLXA 4WVSA 3UEFA 5C0LA 4J47A 3UEDA 3HL5A 2VSLA 3GT9A 4MTZA 1F9XA 4J3YA 4WVUA 1I3OE 3F7HA 3M0DD 3UEHA 3M1DA 4HY4A 2POIA 3CM2A 2OPZA 3MUPA 1QBHA 5C84A 3UEEA 3UIKA 4J44A 2RAWA 1G3FA 3UECA 1G73C 4KMPA 1JD5A 1OXNA 2RAXA 3UW5A 3G76A 1XOXA 3SIQA 3OZ1A 3D9UA 1OXQA 1JD4A 4A0NA 2QFAA 4KJVA 1Q4QA 2I3IA 3F7GA 1SDZA 1F3HA 4HY5A 1TW6A 2POPB 4J46A 4KMNA 4LGEA 3UW4A 3UIHA 4KJUA 1E31A 3D9TA 4OXCA 5C0KA 5C83A 2OPYA 3F7IA 3EYLA 1M4MA 2I3HA 3SIPE 1TFQA
chains in the Genus database with same CATH topology
2JK7A 4J48A 5C3HA 3UEGA 5C3KA 5C7AA 4HY0A 4EC4A 1XB0A 1SE0A 1OY7A 4LGUA 3CM7A 1JD6A 4A0IA 3UIIA 4WVTA 1C9QA 5C7DA 3GTAA 5C7CA 4EB9A 1NW9A 2UVLA 4A0JA 4J45A 1TFTA 3M0AD 3T6PA 3UEIA 5C7BA 3UIGA 3UIJA 1XB1A 2VM5A 4MTIA 4MU7A 2QRAA 3CLXA 4WVSA 3UEFA 5C0LA 4J47A 3UEDA 3HL5A 2VSLA 3GT9A 4MTZA 1F9XA 4J3YA 4WVUA 1I3OE 3F7HA 3M0DD 3UEHA 3M1DA 4HY4A 2POIA 3CM2A 2OPZA 3MUPA 1QBHA 5C84A 3UEEA 3UIKA 4J44A 2RAWA 1G3FA 3UECA 1G73C 4KMPA 1JD5A 1OXNA 2RAXA 3UW5A 3G76A 1XOXA 3SIQA 3OZ1A 3D9UA 1OXQA 1JD4A 4A0NA 2QFAA 4KJVA 1Q4QA 2I3IA 3F7GA 1SDZA 1F3HA 4HY5A 1TW6A 2POPB 4J46A 4KMNA 4LGEA 3UW4A 3UIHA 4KJUA 1E31A 3D9TA 4OXCA 5C0KA 5C83A 2OPYA 3F7IA 3EYLA 1M4MA 2I3HA 3SIPE 1TFQA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2JK7 A;  4J48 A;  5C3H A;  3UEG A;  5C3K A;  5C7A A;  4HY0 A;  4EC4 A;  1XB0 A;  1SE0 A;  1OY7 A;  4LGU A;  3CM7 A;  1JD6 A;  4A0I A;  3UII A;  4WVT A;  1C9Q A;  5C7D A;  3GTA A;  5C7C A;  4EB9 A;  1NW9 A;  2UVL A;  4A0J A;  4J45 A;  1TFT A;  3M0A D;  3T6P A;  3UEI A;  5C7B A;  3UIG A;  3UIJ A;  1XB1 A;  2VM5 A;  4MTI A;  4MU7 A;  2QRA A;  3CLX A;  4WVS A;  3UEF A;  5C0L A;  4J47 A;  3UED A;  3HL5 A;  2VSL A;  3GT9 A;  4MTZ A;  1F9X A;  4J3Y A;  4WVU A;  1I3O E;  3F7H A;  3M0D D;  3UEH A;  3M1D A;  4HY4 A;  2POI A;  3CM2 A;  2OPZ A;  3MUP A;  1QBH A;  5C84 A;  3UEE A;  3UIK A;  4J44 A;  2RAW A;  1G3F A;  3UEC A;  1G73 C;  4KMP A;  1JD5 A;  1OXN A;  2RAX A;  3UW5 A;  3G76 A;  1XOX A;  3SIQ A;  3OZ1 A;  3D9U A;  1OXQ A;  1JD4 A;  4A0N A;  2QFA A;  4KJV A;  1Q4Q A;  2I3I A;  3F7G A;  1SDZ A;  1F3H A;  4HY5 A;  1TW6 A;  2POP B;  4J46 A;  4KMN A;  4LGE A;  3UW4 A;  3UIH A;  4KJU A;  1E31 A;  3D9T A;  4OXC A;  5C0K A;  5C83 A;  2OPY A;  3F7I A;  3EYL A;  1M4M A;  2I3H A;  3SIP E;  1TFQ A; 
#chains in the Genus database with same CATH topology
 2JK7 A;  4J48 A;  5C3H A;  3UEG A;  5C3K A;  5C7A A;  4HY0 A;  4EC4 A;  1XB0 A;  1SE0 A;  1OY7 A;  4LGU A;  3CM7 A;  1JD6 A;  4A0I A;  3UII A;  4WVT A;  1C9Q A;  5C7D A;  3GTA A;  5C7C A;  4EB9 A;  1NW9 A;  2UVL A;  4A0J A;  4J45 A;  1TFT A;  3M0A D;  3T6P A;  3UEI A;  5C7B A;  3UIG A;  3UIJ A;  1XB1 A;  2VM5 A;  4MTI A;  4MU7 A;  2QRA A;  3CLX A;  4WVS A;  3UEF A;  5C0L A;  4J47 A;  3UED A;  3HL5 A;  2VSL A;  3GT9 A;  4MTZ A;  1F9X A;  4J3Y A;  4WVU A;  1I3O E;  3F7H A;  3M0D D;  3UEH A;  3M1D A;  4HY4 A;  2POI A;  3CM2 A;  2OPZ A;  3MUP A;  1QBH A;  5C84 A;  3UEE A;  3UIK A;  4J44 A;  2RAW A;  1G3F A;  3UEC A;  1G73 C;  4KMP A;  1JD5 A;  1OXN A;  2RAX A;  3UW5 A;  3G76 A;  1XOX A;  3SIQ A;  3OZ1 A;  3D9U A;  1OXQ A;  1JD4 A;  4A0N A;  2QFA A;  4KJV A;  1Q4Q A;  2I3I A;  3F7G A;  1SDZ A;  1F3H A;  4HY5 A;  1TW6 A;  2POP B;  4J46 A;  4KMN A;  4LGE A;  3UW4 A;  3UIH A;  4KJU A;  1E31 A;  3D9T A;  4OXC A;  5C0K A;  5C83 A;  2OPY A;  3F7I A;  3EYL A;  1M4M A;  2I3H A;  3SIP E;  1TFQ A; 
#chains in the Genus database with same CATH homology
 2JK7 A;  4J48 A;  5C3H A;  3UEG A;  5C3K A;  5C7A A;  4HY0 A;  4EC4 A;  1XB0 A;  1SE0 A;  1OY7 A;  4LGU A;  3CM7 A;  1JD6 A;  4A0I A;  3UII A;  4WVT A;  1C9Q A;  5C7D A;  3GTA A;  5C7C A;  4EB9 A;  1NW9 A;  2UVL A;  4A0J A;  4J45 A;  1TFT A;  3M0A D;  3T6P A;  3UEI A;  5C7B A;  3UIG A;  3UIJ A;  1XB1 A;  2VM5 A;  4MTI A;  4MU7 A;  2QRA A;  3CLX A;  4WVS A;  3UEF A;  5C0L A;  4J47 A;  3UED A;  3HL5 A;  2VSL A;  3GT9 A;  4MTZ A;  1F9X A;  4J3Y A;  4WVU A;  1I3O E;  3F7H A;  3M0D D;  3UEH A;  3M1D A;  4HY4 A;  2POI A;  3CM2 A;  2OPZ A;  3MUP A;  1QBH A;  5C84 A;  3UEE A;  3UIK A;  4J44 A;  2RAW A;  1G3F A;  3UEC A;  1G73 C;  4KMP A;  1JD5 A;  1OXN A;  2RAX A;  3UW5 A;  3G76 A;  1XOX A;  3SIQ A;  3OZ1 A;  3D9U A;  1OXQ A;  1JD4 A;  4A0N A;  2QFA A;  4KJV A;  1Q4Q A;  2I3I A;  3F7G A;  1SDZ A;  1F3H A;  4HY5 A;  1TW6 A;  2POP B;  4J46 A;  4KMN A;  4LGE A;  3UW4 A;  3UIH A;  4KJU A;  1E31 A;  3D9T A;  4OXC A;  5C0K A;  5C83 A;  2OPY A;  3F7I A;  3EYL A;  1M4M A;  2I3H A;  3SIP E;  1TFQ A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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