4J45A

Crystal structure of xiap-bir2 domain with ataa bound
Total Genus 20
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
20
sequence length
83
structure length
83
Chain Sequence
GTIYPRNPAMYSEEARLKSFQNWPDYAHLTPRELASAGLYYTGIGDQVQCFACGGKLKNWEPGDRAWSEHRRHFPNCFFVLGR
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title The structure of XIAP BIR2: understanding the selectivity of the BIR domains.
pubmed doi rcsb
molecule tags Apoptosis
source organism Homo sapiens
molecule keywords E3 ubiquitin-protein ligase XIAP
total genus 20
structure length 83
sequence length 83
chains with identical sequence C
ec nomenclature ec 2.3.2.27: RING-type E3 ubiquitin transferase.
pdb deposition date 2013-02-06

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00653 BIR Inhibitor of Apoptosis domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.1170.10 Mainly Alpha Orthogonal Bundle Inhibitor Of Apoptosis Protein (2mihbC-IAP-1); Chain A Inhibitor Of Apoptosis Protein (2mihbC-IAP-1); Chain A 4j45A00
3UIIA 3T6PA 3D9TA 4A0NA 4LGEA 1SE0A 4MTIA 3UW4A 4J47A 3M1DA 1JD6A 1JD5A 4J46A 1XB0A 1Q4QA 4OXCA 3SIQA 2QRAA 5C7CA 4J45A 2OPZA 3UW5A 1TFTA 1TW6A 3CM7A 2I3IA 4HY5A 4MU7A 3D9UA 1F9XA 4KMNA 3UEHA 4HY0A 2POIA 1TFQA 1M4MA 5C83A 1QBHA 5C3HA 3UEIA 3CLXA 3MUPA 5C7AA 2VSLA 3UIGA 4J48A 3UEGA 3M0DD 2RAXA 3UIKA 3F7IA 4A0JA 3M0AD 1G3FA 4MTZA 1F3HA 2RAWA 3OZ1A 5C3KA 1G73C 2I3HA 4WVSA 3SIPE 4WVTA 1C9QA 4A0IA 4KJVA 2JK7A 5C0LA 3UEEA 1OXQA 5C0KA 3UIHA 1XB1A 3UIJA 5C84A 3UECA 1OY7A 4KMPA 1JD4A 2UVLA 1E31A 4HY4A 1OXNA 2OPYA 4EC4A 4KJUA 1XOXA 2VM5A 3CM2A 3GTAA 3F7GA 1I3OE 2QFAA 5C7BA 3GT9A 3G76A 4EB9A 1NW9A 4J44A 3UEFA 3HL5A 4LGUA 5C7DA 2POPB 4WVUA 1SDZA 3UEDA 3EYLA 3F7HA 4J3YA
chains in the Genus database with same CATH superfamily
3UIIA 3T6PA 3D9TA 4A0NA 4LGEA 1SE0A 4MTIA 3UW4A 4J47A 3M1DA 1JD6A 1JD5A 4J46A 1XB0A 1Q4QA 4OXCA 3SIQA 2QRAA 5C7CA 4J45A 2OPZA 3UW5A 1TFTA 1TW6A 3CM7A 2I3IA 4HY5A 4MU7A 3D9UA 1F9XA 4KMNA 3UEHA 4HY0A 2POIA 1TFQA 1M4MA 5C83A 1QBHA 5C3HA 3UEIA 3CLXA 3MUPA 5C7AA 2VSLA 3UIGA 4J48A 3UEGA 3M0DD 2RAXA 3UIKA 3F7IA 4A0JA 3M0AD 1G3FA 4MTZA 1F3HA 2RAWA 3OZ1A 5C3KA 1G73C 2I3HA 4WVSA 3SIPE 4WVTA 1C9QA 4A0IA 4KJVA 2JK7A 5C0LA 3UEEA 1OXQA 5C0KA 3UIHA 1XB1A 3UIJA 5C84A 3UECA 1OY7A 4KMPA 1JD4A 2UVLA 1E31A 4HY4A 1OXNA 2OPYA 4EC4A 4KJUA 1XOXA 2VM5A 3CM2A 3GTAA 3F7GA 1I3OE 2QFAA 5C7BA 3GT9A 3G76A 4EB9A 1NW9A 4J44A 3UEFA 3HL5A 4LGUA 5C7DA 2POPB 4WVUA 1SDZA 3UEDA 3EYLA 3F7HA 4J3YA
chains in the Genus database with same CATH topology
3UIIA 3T6PA 3D9TA 4A0NA 4LGEA 1SE0A 4MTIA 3UW4A 4J47A 3M1DA 1JD6A 1JD5A 4J46A 1XB0A 1Q4QA 4OXCA 3SIQA 2QRAA 5C7CA 4J45A 2OPZA 3UW5A 1TFTA 1TW6A 3CM7A 2I3IA 4HY5A 4MU7A 3D9UA 1F9XA 4KMNA 3UEHA 4HY0A 2POIA 1TFQA 1M4MA 5C83A 1QBHA 5C3HA 3UEIA 3CLXA 3MUPA 5C7AA 2VSLA 3UIGA 4J48A 3UEGA 3M0DD 2RAXA 3UIKA 3F7IA 4A0JA 3M0AD 1G3FA 4MTZA 1F3HA 2RAWA 3OZ1A 5C3KA 1G73C 2I3HA 4WVSA 3SIPE 4WVTA 1C9QA 4A0IA 4KJVA 2JK7A 5C0LA 3UEEA 1OXQA 5C0KA 3UIHA 1XB1A 3UIJA 5C84A 3UECA 1OY7A 4KMPA 1JD4A 2UVLA 1E31A 4HY4A 1OXNA 2OPYA 4EC4A 4KJUA 1XOXA 2VM5A 3CM2A 3GTAA 3F7GA 1I3OE 2QFAA 5C7BA 3GT9A 3G76A 4EB9A 1NW9A 4J44A 3UEFA 3HL5A 4LGUA 5C7DA 2POPB 4WVUA 1SDZA 3UEDA 3EYLA 3F7HA 4J3YA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3UII A;  3T6P A;  3D9T A;  4A0N A;  4LGE A;  1SE0 A;  4MTI A;  3UW4 A;  4J47 A;  3M1D A;  1JD6 A;  1JD5 A;  4J46 A;  1XB0 A;  1Q4Q A;  4OXC A;  3SIQ A;  2QRA A;  5C7C A;  4J45 A;  2OPZ A;  3UW5 A;  1TFT A;  1TW6 A;  3CM7 A;  2I3I A;  4HY5 A;  4MU7 A;  3D9U A;  1F9X A;  4KMN A;  3UEH A;  4HY0 A;  2POI A;  1TFQ A;  1M4M A;  5C83 A;  1QBH A;  5C3H A;  3UEI A;  3CLX A;  3MUP A;  5C7A A;  2VSL A;  3UIG A;  4J48 A;  3UEG A;  3M0D D;  2RAX A;  3UIK A;  3F7I A;  4A0J A;  3M0A D;  1G3F A;  4MTZ A;  1F3H A;  2RAW A;  3OZ1 A;  5C3K A;  1G73 C;  2I3H A;  4WVS A;  3SIP E;  4WVT A;  1C9Q A;  4A0I A;  4KJV A;  2JK7 A;  5C0L A;  3UEE A;  1OXQ A;  5C0K A;  3UIH A;  1XB1 A;  3UIJ A;  5C84 A;  3UEC A;  1OY7 A;  4KMP A;  1JD4 A;  2UVL A;  1E31 A;  4HY4 A;  1OXN A;  2OPY A;  4EC4 A;  4KJU A;  1XOX A;  2VM5 A;  3CM2 A;  3GTA A;  3F7G A;  1I3O E;  2QFA A;  5C7B A;  3GT9 A;  3G76 A;  4EB9 A;  1NW9 A;  4J44 A;  3UEF A;  3HL5 A;  4LGU A;  5C7D A;  2POP B;  4WVU A;  1SDZ A;  3UED A;  3EYL A;  3F7H A;  4J3Y A; 
#chains in the Genus database with same CATH topology
 3UII A;  3T6P A;  3D9T A;  4A0N A;  4LGE A;  1SE0 A;  4MTI A;  3UW4 A;  4J47 A;  3M1D A;  1JD6 A;  1JD5 A;  4J46 A;  1XB0 A;  1Q4Q A;  4OXC A;  3SIQ A;  2QRA A;  5C7C A;  4J45 A;  2OPZ A;  3UW5 A;  1TFT A;  1TW6 A;  3CM7 A;  2I3I A;  4HY5 A;  4MU7 A;  3D9U A;  1F9X A;  4KMN A;  3UEH A;  4HY0 A;  2POI A;  1TFQ A;  1M4M A;  5C83 A;  1QBH A;  5C3H A;  3UEI A;  3CLX A;  3MUP A;  5C7A A;  2VSL A;  3UIG A;  4J48 A;  3UEG A;  3M0D D;  2RAX A;  3UIK A;  3F7I A;  4A0J A;  3M0A D;  1G3F A;  4MTZ A;  1F3H A;  2RAW A;  3OZ1 A;  5C3K A;  1G73 C;  2I3H A;  4WVS A;  3SIP E;  4WVT A;  1C9Q A;  4A0I A;  4KJV A;  2JK7 A;  5C0L A;  3UEE A;  1OXQ A;  5C0K A;  3UIH A;  1XB1 A;  3UIJ A;  5C84 A;  3UEC A;  1OY7 A;  4KMP A;  1JD4 A;  2UVL A;  1E31 A;  4HY4 A;  1OXN A;  2OPY A;  4EC4 A;  4KJU A;  1XOX A;  2VM5 A;  3CM2 A;  3GTA A;  3F7G A;  1I3O E;  2QFA A;  5C7B A;  3GT9 A;  3G76 A;  4EB9 A;  1NW9 A;  4J44 A;  3UEF A;  3HL5 A;  4LGU A;  5C7D A;  2POP B;  4WVU A;  1SDZ A;  3UED A;  3EYL A;  3F7H A;  4J3Y A; 
#chains in the Genus database with same CATH homology
 3UII A;  3T6P A;  3D9T A;  4A0N A;  4LGE A;  1SE0 A;  4MTI A;  3UW4 A;  4J47 A;  3M1D A;  1JD6 A;  1JD5 A;  4J46 A;  1XB0 A;  1Q4Q A;  4OXC A;  3SIQ A;  2QRA A;  5C7C A;  4J45 A;  2OPZ A;  3UW5 A;  1TFT A;  1TW6 A;  3CM7 A;  2I3I A;  4HY5 A;  4MU7 A;  3D9U A;  1F9X A;  4KMN A;  3UEH A;  4HY0 A;  2POI A;  1TFQ A;  1M4M A;  5C83 A;  1QBH A;  5C3H A;  3UEI A;  3CLX A;  3MUP A;  5C7A A;  2VSL A;  3UIG A;  4J48 A;  3UEG A;  3M0D D;  2RAX A;  3UIK A;  3F7I A;  4A0J A;  3M0A D;  1G3F A;  4MTZ A;  1F3H A;  2RAW A;  3OZ1 A;  5C3K A;  1G73 C;  2I3H A;  4WVS A;  3SIP E;  4WVT A;  1C9Q A;  4A0I A;  4KJV A;  2JK7 A;  5C0L A;  3UEE A;  1OXQ A;  5C0K A;  3UIH A;  1XB1 A;  3UIJ A;  5C84 A;  3UEC A;  1OY7 A;  4KMP A;  1JD4 A;  2UVL A;  1E31 A;  4HY4 A;  1OXN A;  2OPY A;  4EC4 A;  4KJU A;  1XOX A;  2VM5 A;  3CM2 A;  3GTA A;  3F7G A;  1I3O E;  2QFA A;  5C7B A;  3GT9 A;  3G76 A;  4EB9 A;  1NW9 A;  4J44 A;  3UEF A;  3HL5 A;  4LGU A;  5C7D A;  2POP B;  4WVU A;  1SDZ A;  3UED A;  3EYL A;  3F7H A;  4J3Y A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...