4J46A

Crystal structure of xiap-bir2 domain with avpi bound
Total Genus 21
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
21
sequence length
83
structure length
83
Chain Sequence
GTIYPRNPAMYSEEARLKSFQNWPDYAHLTPRELASAGLYYTGIGDQVQCFACGGKLKNWEPGDRAWSEHRRHFPNCFFVLGR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title The structure of XIAP BIR2: understanding the selectivity of the BIR domains.
pubmed doi rcsb
molecule tags Apoptosis
source organism Homo sapiens
molecule keywords E3 ubiquitin-protein ligase XIAP
total genus 21
structure length 83
sequence length 83
chains with identical sequence C
ec nomenclature ec 2.3.2.27: RING-type E3 ubiquitin transferase.
pdb deposition date 2013-02-06

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00653 BIR Inhibitor of Apoptosis domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.1170.10 Mainly Alpha Orthogonal Bundle Inhibitor Of Apoptosis Protein (2mihbC-IAP-1); Chain A Inhibitor Of Apoptosis Protein (2mihbC-IAP-1); Chain A 4j46A00
4KJUA 2QRAA 4J47A 5C83A 4HY5A 3SIPE 3UIGA 2OPYA 3CLXA 1JD5A 3GTAA 4J3YA 3HL5A 1TFTA 3M0AD 5C7BA 4OXCA 4HY4A 4MU7A 2POPB 3M0DD 1XB1A 1Q4QA 4EB9A 3GT9A 4J46A 2VSLA 2I3IA 1QBHA 4A0JA 5C84A 3UEIA 1F9XA 2RAWA 3F7HA 4J48A 2OPZA 1SDZA 4J44A 1JD4A 3D9UA 3UEGA 3SIQA 1SE0A 4A0NA 2I3HA 3CM2A 2UVLA 3F7GA 1G3FA 4WVUA 5C3KA 3EYLA 4LGUA 1OXQA 1XB0A 3UW4A 3UEDA 5C3HA 4MTIA 1NW9A 4WVTA 5C0KA 3UW5A 5C0LA 4HY0A 1F3HA 3UIKA 1TFQA 2RAXA 1XOXA 3UEHA 1C9QA 1TW6A 3D9TA 4MTZA 4KJVA 3UECA 3UIHA 3UEEA 4A0IA 5C7DA 3MUPA 1G73C 2POIA 3T6PA 3CM7A 3OZ1A 2QFAA 3UEFA 1I3OE 5C7CA 3F7IA 5C7AA 1E31A 3UIJA 1OY7A 1M4MA 2JK7A 4KMPA 4J45A 1JD6A 2VM5A 3M1DA 3UIIA 1OXNA 3G76A 4KMNA 4EC4A 4WVSA 4LGEA
chains in the Genus database with same CATH superfamily
4KJUA 2QRAA 4J47A 5C83A 4HY5A 3SIPE 3UIGA 2OPYA 3CLXA 1JD5A 3GTAA 4J3YA 3HL5A 1TFTA 3M0AD 5C7BA 4OXCA 4HY4A 4MU7A 2POPB 3M0DD 1XB1A 1Q4QA 4EB9A 3GT9A 4J46A 2VSLA 2I3IA 1QBHA 4A0JA 5C84A 3UEIA 1F9XA 2RAWA 3F7HA 4J48A 2OPZA 1SDZA 4J44A 1JD4A 3D9UA 3UEGA 3SIQA 1SE0A 4A0NA 2I3HA 3CM2A 2UVLA 3F7GA 1G3FA 4WVUA 5C3KA 3EYLA 4LGUA 1OXQA 1XB0A 3UW4A 3UEDA 5C3HA 4MTIA 1NW9A 4WVTA 5C0KA 3UW5A 5C0LA 4HY0A 1F3HA 3UIKA 1TFQA 2RAXA 1XOXA 3UEHA 1C9QA 1TW6A 3D9TA 4MTZA 4KJVA 3UECA 3UIHA 3UEEA 4A0IA 5C7DA 3MUPA 1G73C 2POIA 3T6PA 3CM7A 3OZ1A 2QFAA 3UEFA 1I3OE 5C7CA 3F7IA 5C7AA 1E31A 3UIJA 1OY7A 1M4MA 2JK7A 4KMPA 4J45A 1JD6A 2VM5A 3M1DA 3UIIA 1OXNA 3G76A 4KMNA 4EC4A 4WVSA 4LGEA
chains in the Genus database with same CATH topology
4KJUA 2QRAA 4J47A 5C83A 4HY5A 3SIPE 3UIGA 2OPYA 3CLXA 1JD5A 3GTAA 4J3YA 3HL5A 1TFTA 3M0AD 5C7BA 4OXCA 4HY4A 4MU7A 2POPB 3M0DD 1XB1A 1Q4QA 4EB9A 3GT9A 4J46A 2VSLA 2I3IA 1QBHA 4A0JA 5C84A 3UEIA 1F9XA 2RAWA 3F7HA 4J48A 2OPZA 1SDZA 4J44A 1JD4A 3D9UA 3UEGA 3SIQA 1SE0A 4A0NA 2I3HA 3CM2A 2UVLA 3F7GA 1G3FA 4WVUA 5C3KA 3EYLA 4LGUA 1OXQA 1XB0A 3UW4A 3UEDA 5C3HA 4MTIA 1NW9A 4WVTA 5C0KA 3UW5A 5C0LA 4HY0A 1F3HA 3UIKA 1TFQA 2RAXA 1XOXA 3UEHA 1C9QA 1TW6A 3D9TA 4MTZA 4KJVA 3UECA 3UIHA 3UEEA 4A0IA 5C7DA 3MUPA 1G73C 2POIA 3T6PA 3CM7A 3OZ1A 2QFAA 3UEFA 1I3OE 5C7CA 3F7IA 5C7AA 1E31A 3UIJA 1OY7A 1M4MA 2JK7A 4KMPA 4J45A 1JD6A 2VM5A 3M1DA 3UIIA 1OXNA 3G76A 4KMNA 4EC4A 4WVSA 4LGEA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4KJU A;  2QRA A;  4J47 A;  5C83 A;  4HY5 A;  3SIP E;  3UIG A;  2OPY A;  3CLX A;  1JD5 A;  3GTA A;  4J3Y A;  3HL5 A;  1TFT A;  3M0A D;  5C7B A;  4OXC A;  4HY4 A;  4MU7 A;  2POP B;  3M0D D;  1XB1 A;  1Q4Q A;  4EB9 A;  3GT9 A;  4J46 A;  2VSL A;  2I3I A;  1QBH A;  4A0J A;  5C84 A;  3UEI A;  1F9X A;  2RAW A;  3F7H A;  4J48 A;  2OPZ A;  1SDZ A;  4J44 A;  1JD4 A;  3D9U A;  3UEG A;  3SIQ A;  1SE0 A;  4A0N A;  2I3H A;  3CM2 A;  2UVL A;  3F7G A;  1G3F A;  4WVU A;  5C3K A;  3EYL A;  4LGU A;  1OXQ A;  1XB0 A;  3UW4 A;  3UED A;  5C3H A;  4MTI A;  1NW9 A;  4WVT A;  5C0K A;  3UW5 A;  5C0L A;  4HY0 A;  1F3H A;  3UIK A;  1TFQ A;  2RAX A;  1XOX A;  3UEH A;  1C9Q A;  1TW6 A;  3D9T A;  4MTZ A;  4KJV A;  3UEC A;  3UIH A;  3UEE A;  4A0I A;  5C7D A;  3MUP A;  1G73 C;  2POI A;  3T6P A;  3CM7 A;  3OZ1 A;  2QFA A;  3UEF A;  1I3O E;  5C7C A;  3F7I A;  5C7A A;  1E31 A;  3UIJ A;  1OY7 A;  1M4M A;  2JK7 A;  4KMP A;  4J45 A;  1JD6 A;  2VM5 A;  3M1D A;  3UII A;  1OXN A;  3G76 A;  4KMN A;  4EC4 A;  4WVS A;  4LGE A; 
#chains in the Genus database with same CATH topology
 4KJU A;  2QRA A;  4J47 A;  5C83 A;  4HY5 A;  3SIP E;  3UIG A;  2OPY A;  3CLX A;  1JD5 A;  3GTA A;  4J3Y A;  3HL5 A;  1TFT A;  3M0A D;  5C7B A;  4OXC A;  4HY4 A;  4MU7 A;  2POP B;  3M0D D;  1XB1 A;  1Q4Q A;  4EB9 A;  3GT9 A;  4J46 A;  2VSL A;  2I3I A;  1QBH A;  4A0J A;  5C84 A;  3UEI A;  1F9X A;  2RAW A;  3F7H A;  4J48 A;  2OPZ A;  1SDZ A;  4J44 A;  1JD4 A;  3D9U A;  3UEG A;  3SIQ A;  1SE0 A;  4A0N A;  2I3H A;  3CM2 A;  2UVL A;  3F7G A;  1G3F A;  4WVU A;  5C3K A;  3EYL A;  4LGU A;  1OXQ A;  1XB0 A;  3UW4 A;  3UED A;  5C3H A;  4MTI A;  1NW9 A;  4WVT A;  5C0K A;  3UW5 A;  5C0L A;  4HY0 A;  1F3H A;  3UIK A;  1TFQ A;  2RAX A;  1XOX A;  3UEH A;  1C9Q A;  1TW6 A;  3D9T A;  4MTZ A;  4KJV A;  3UEC A;  3UIH A;  3UEE A;  4A0I A;  5C7D A;  3MUP A;  1G73 C;  2POI A;  3T6P A;  3CM7 A;  3OZ1 A;  2QFA A;  3UEF A;  1I3O E;  5C7C A;  3F7I A;  5C7A A;  1E31 A;  3UIJ A;  1OY7 A;  1M4M A;  2JK7 A;  4KMP A;  4J45 A;  1JD6 A;  2VM5 A;  3M1D A;  3UII A;  1OXN A;  3G76 A;  4KMN A;  4EC4 A;  4WVS A;  4LGE A; 
#chains in the Genus database with same CATH homology
 4KJU A;  2QRA A;  4J47 A;  5C83 A;  4HY5 A;  3SIP E;  3UIG A;  2OPY A;  3CLX A;  1JD5 A;  3GTA A;  4J3Y A;  3HL5 A;  1TFT A;  3M0A D;  5C7B A;  4OXC A;  4HY4 A;  4MU7 A;  2POP B;  3M0D D;  1XB1 A;  1Q4Q A;  4EB9 A;  3GT9 A;  4J46 A;  2VSL A;  2I3I A;  1QBH A;  4A0J A;  5C84 A;  3UEI A;  1F9X A;  2RAW A;  3F7H A;  4J48 A;  2OPZ A;  1SDZ A;  4J44 A;  1JD4 A;  3D9U A;  3UEG A;  3SIQ A;  1SE0 A;  4A0N A;  2I3H A;  3CM2 A;  2UVL A;  3F7G A;  1G3F A;  4WVU A;  5C3K A;  3EYL A;  4LGU A;  1OXQ A;  1XB0 A;  3UW4 A;  3UED A;  5C3H A;  4MTI A;  1NW9 A;  4WVT A;  5C0K A;  3UW5 A;  5C0L A;  4HY0 A;  1F3H A;  3UIK A;  1TFQ A;  2RAX A;  1XOX A;  3UEH A;  1C9Q A;  1TW6 A;  3D9T A;  4MTZ A;  4KJV A;  3UEC A;  3UIH A;  3UEE A;  4A0I A;  5C7D A;  3MUP A;  1G73 C;  2POI A;  3T6P A;  3CM7 A;  3OZ1 A;  2QFA A;  3UEF A;  1I3O E;  5C7C A;  3F7I A;  5C7A A;  1E31 A;  3UIJ A;  1OY7 A;  1M4M A;  2JK7 A;  4KMP A;  4J45 A;  1JD6 A;  2VM5 A;  3M1D A;  3UII A;  1OXN A;  3G76 A;  4KMN A;  4EC4 A;  4WVS A;  4LGE A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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