4J47A

Crystal structure of xiap-bir2 domain with svpi bound
Total Genus 21
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
21
sequence length
83
structure length
83
Chain Sequence
GTIYPRNPAMYSEEARLKSFQNWPDYAHLTPRELASAGLYYTGIGDQVQCFACGGKLKNWEPGDRAWSEHRRHFPNCFFVLGR
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title The structure of XIAP BIR2: understanding the selectivity of the BIR domains.
pubmed doi rcsb
molecule tags Apoptosis
source organism Homo sapiens
molecule keywords E3 ubiquitin-protein ligase XIAP
total genus 21
structure length 83
sequence length 83
chains with identical sequence C
ec nomenclature ec 2.3.2.27: RING-type E3 ubiquitin transferase.
pdb deposition date 2013-02-06

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00653 BIR Inhibitor of Apoptosis domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.1170.10 Mainly Alpha Orthogonal Bundle Inhibitor Of Apoptosis Protein (2mihbC-IAP-1); Chain A Inhibitor Of Apoptosis Protein (2mihbC-IAP-1); Chain A 4j47A00
5C7DA 1SDZA 4LGUA 4WVSA 3UIHA 3F7IA 1XOXA 3HL5A 3UEIA 1JD5A 5C3KA 1C9QA 3MUPA 4OXCA 3G76A 1JD4A 2VSLA 1OXQA 5C7AA 3CLXA 5C7CA 1XB1A 2POIA 3OZ1A 5C83A 4EB9A 3D9TA 4MTIA 3M0AD 4HY0A 2VM5A 5C3HA 3UIJA 1F3HA 5C0LA 3T6PA 3UEHA 3UECA 2RAXA 3GT9A 1JD6A 3UEGA 5C7BA 4MTZA 1NW9A 4J47A 4J45A 4KJVA 4EC4A 1I3OE 3UW4A 4HY4A 2RAWA 2UVLA 2OPYA 1TW6A 4J3YA 1F9XA 3GTAA 4MU7A 3UEDA 3UEEA 4J46A 1TFTA 3UW5A 2QRAA 3EYLA 3UIKA 3UEFA 3D9UA 4KMNA 2JK7A 3F7HA 4KMPA 1G73C 1E31A 3SIQA 4J48A 3SIPE 1SE0A 4WVUA 3CM2A 1M4MA 5C0KA 1TFQA 2OPZA 4J44A 1QBHA 3F7GA 3CM7A 1XB0A 4WVTA 2I3IA 5C84A 4KJUA 2POPB 1Q4QA 3M0DD 3M1DA 2QFAA 4HY5A 1G3FA 1OY7A 4A0IA 2I3HA 1OXNA 4LGEA 3UIIA 3UIGA 4A0JA 4A0NA
chains in the Genus database with same CATH superfamily
5C7DA 1SDZA 4LGUA 4WVSA 3UIHA 3F7IA 1XOXA 3HL5A 3UEIA 1JD5A 5C3KA 1C9QA 3MUPA 4OXCA 3G76A 1JD4A 2VSLA 1OXQA 5C7AA 3CLXA 5C7CA 1XB1A 2POIA 3OZ1A 5C83A 4EB9A 3D9TA 4MTIA 3M0AD 4HY0A 2VM5A 5C3HA 3UIJA 1F3HA 5C0LA 3T6PA 3UEHA 3UECA 2RAXA 3GT9A 1JD6A 3UEGA 5C7BA 4MTZA 1NW9A 4J47A 4J45A 4KJVA 4EC4A 1I3OE 3UW4A 4HY4A 2RAWA 2UVLA 2OPYA 1TW6A 4J3YA 1F9XA 3GTAA 4MU7A 3UEDA 3UEEA 4J46A 1TFTA 3UW5A 2QRAA 3EYLA 3UIKA 3UEFA 3D9UA 4KMNA 2JK7A 3F7HA 4KMPA 1G73C 1E31A 3SIQA 4J48A 3SIPE 1SE0A 4WVUA 3CM2A 1M4MA 5C0KA 1TFQA 2OPZA 4J44A 1QBHA 3F7GA 3CM7A 1XB0A 4WVTA 2I3IA 5C84A 4KJUA 2POPB 1Q4QA 3M0DD 3M1DA 2QFAA 4HY5A 1G3FA 1OY7A 4A0IA 2I3HA 1OXNA 4LGEA 3UIIA 3UIGA 4A0JA 4A0NA
chains in the Genus database with same CATH topology
5C7DA 1SDZA 4LGUA 4WVSA 3UIHA 3F7IA 1XOXA 3HL5A 3UEIA 1JD5A 5C3KA 1C9QA 3MUPA 4OXCA 3G76A 1JD4A 2VSLA 1OXQA 5C7AA 3CLXA 5C7CA 1XB1A 2POIA 3OZ1A 5C83A 4EB9A 3D9TA 4MTIA 3M0AD 4HY0A 2VM5A 5C3HA 3UIJA 1F3HA 5C0LA 3T6PA 3UEHA 3UECA 2RAXA 3GT9A 1JD6A 3UEGA 5C7BA 4MTZA 1NW9A 4J47A 4J45A 4KJVA 4EC4A 1I3OE 3UW4A 4HY4A 2RAWA 2UVLA 2OPYA 1TW6A 4J3YA 1F9XA 3GTAA 4MU7A 3UEDA 3UEEA 4J46A 1TFTA 3UW5A 2QRAA 3EYLA 3UIKA 3UEFA 3D9UA 4KMNA 2JK7A 3F7HA 4KMPA 1G73C 1E31A 3SIQA 4J48A 3SIPE 1SE0A 4WVUA 3CM2A 1M4MA 5C0KA 1TFQA 2OPZA 4J44A 1QBHA 3F7GA 3CM7A 1XB0A 4WVTA 2I3IA 5C84A 4KJUA 2POPB 1Q4QA 3M0DD 3M1DA 2QFAA 4HY5A 1G3FA 1OY7A 4A0IA 2I3HA 1OXNA 4LGEA 3UIIA 3UIGA 4A0JA 4A0NA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5C7D A;  1SDZ A;  4LGU A;  4WVS A;  3UIH A;  3F7I A;  1XOX A;  3HL5 A;  3UEI A;  1JD5 A;  5C3K A;  1C9Q A;  3MUP A;  4OXC A;  3G76 A;  1JD4 A;  2VSL A;  1OXQ A;  5C7A A;  3CLX A;  5C7C A;  1XB1 A;  2POI A;  3OZ1 A;  5C83 A;  4EB9 A;  3D9T A;  4MTI A;  3M0A D;  4HY0 A;  2VM5 A;  5C3H A;  3UIJ A;  1F3H A;  5C0L A;  3T6P A;  3UEH A;  3UEC A;  2RAX A;  3GT9 A;  1JD6 A;  3UEG A;  5C7B A;  4MTZ A;  1NW9 A;  4J47 A;  4J45 A;  4KJV A;  4EC4 A;  1I3O E;  3UW4 A;  4HY4 A;  2RAW A;  2UVL A;  2OPY A;  1TW6 A;  4J3Y A;  1F9X A;  3GTA A;  4MU7 A;  3UED A;  3UEE A;  4J46 A;  1TFT A;  3UW5 A;  2QRA A;  3EYL A;  3UIK A;  3UEF A;  3D9U A;  4KMN A;  2JK7 A;  3F7H A;  4KMP A;  1G73 C;  1E31 A;  3SIQ A;  4J48 A;  3SIP E;  1SE0 A;  4WVU A;  3CM2 A;  1M4M A;  5C0K A;  1TFQ A;  2OPZ A;  4J44 A;  1QBH A;  3F7G A;  3CM7 A;  1XB0 A;  4WVT A;  2I3I A;  5C84 A;  4KJU A;  2POP B;  1Q4Q A;  3M0D D;  3M1D A;  2QFA A;  4HY5 A;  1G3F A;  1OY7 A;  4A0I A;  2I3H A;  1OXN A;  4LGE A;  3UII A;  3UIG A;  4A0J A;  4A0N A; 
#chains in the Genus database with same CATH topology
 5C7D A;  1SDZ A;  4LGU A;  4WVS A;  3UIH A;  3F7I A;  1XOX A;  3HL5 A;  3UEI A;  1JD5 A;  5C3K A;  1C9Q A;  3MUP A;  4OXC A;  3G76 A;  1JD4 A;  2VSL A;  1OXQ A;  5C7A A;  3CLX A;  5C7C A;  1XB1 A;  2POI A;  3OZ1 A;  5C83 A;  4EB9 A;  3D9T A;  4MTI A;  3M0A D;  4HY0 A;  2VM5 A;  5C3H A;  3UIJ A;  1F3H A;  5C0L A;  3T6P A;  3UEH A;  3UEC A;  2RAX A;  3GT9 A;  1JD6 A;  3UEG A;  5C7B A;  4MTZ A;  1NW9 A;  4J47 A;  4J45 A;  4KJV A;  4EC4 A;  1I3O E;  3UW4 A;  4HY4 A;  2RAW A;  2UVL A;  2OPY A;  1TW6 A;  4J3Y A;  1F9X A;  3GTA A;  4MU7 A;  3UED A;  3UEE A;  4J46 A;  1TFT A;  3UW5 A;  2QRA A;  3EYL A;  3UIK A;  3UEF A;  3D9U A;  4KMN A;  2JK7 A;  3F7H A;  4KMP A;  1G73 C;  1E31 A;  3SIQ A;  4J48 A;  3SIP E;  1SE0 A;  4WVU A;  3CM2 A;  1M4M A;  5C0K A;  1TFQ A;  2OPZ A;  4J44 A;  1QBH A;  3F7G A;  3CM7 A;  1XB0 A;  4WVT A;  2I3I A;  5C84 A;  4KJU A;  2POP B;  1Q4Q A;  3M0D D;  3M1D A;  2QFA A;  4HY5 A;  1G3F A;  1OY7 A;  4A0I A;  2I3H A;  1OXN A;  4LGE A;  3UII A;  3UIG A;  4A0J A;  4A0N A; 
#chains in the Genus database with same CATH homology
 5C7D A;  1SDZ A;  4LGU A;  4WVS A;  3UIH A;  3F7I A;  1XOX A;  3HL5 A;  3UEI A;  1JD5 A;  5C3K A;  1C9Q A;  3MUP A;  4OXC A;  3G76 A;  1JD4 A;  2VSL A;  1OXQ A;  5C7A A;  3CLX A;  5C7C A;  1XB1 A;  2POI A;  3OZ1 A;  5C83 A;  4EB9 A;  3D9T A;  4MTI A;  3M0A D;  4HY0 A;  2VM5 A;  5C3H A;  3UIJ A;  1F3H A;  5C0L A;  3T6P A;  3UEH A;  3UEC A;  2RAX A;  3GT9 A;  1JD6 A;  3UEG A;  5C7B A;  4MTZ A;  1NW9 A;  4J47 A;  4J45 A;  4KJV A;  4EC4 A;  1I3O E;  3UW4 A;  4HY4 A;  2RAW A;  2UVL A;  2OPY A;  1TW6 A;  4J3Y A;  1F9X A;  3GTA A;  4MU7 A;  3UED A;  3UEE A;  4J46 A;  1TFT A;  3UW5 A;  2QRA A;  3EYL A;  3UIK A;  3UEF A;  3D9U A;  4KMN A;  2JK7 A;  3F7H A;  4KMP A;  1G73 C;  1E31 A;  3SIQ A;  4J48 A;  3SIP E;  1SE0 A;  4WVU A;  3CM2 A;  1M4M A;  5C0K A;  1TFQ A;  2OPZ A;  4J44 A;  1QBH A;  3F7G A;  3CM7 A;  1XB0 A;  4WVT A;  2I3I A;  5C84 A;  4KJU A;  2POP B;  1Q4Q A;  3M0D D;  3M1D A;  2QFA A;  4HY5 A;  1G3F A;  1OY7 A;  4A0I A;  2I3H A;  1OXN A;  4LGE A;  3UII A;  3UIG A;  4A0J A;  4A0N A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...