4J48A

Crystal structure of xiap-bir2 domain with amrv bound
Total Genus 21
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
21
sequence length
84
structure length
84
Chain Sequence
GTIYPRNPAMYSEEARLKSFQNWPDYAHLTPRELASAGLYYTGIGDQVQCFACGGKLKNWEPGDRAWSEHRRHFPNCFFVLGRN
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title The structure of XIAP BIR2: understanding the selectivity of the BIR domains.
pubmed doi rcsb
molecule tags Apoptosis
source organism Homo sapiens
molecule keywords E3 ubiquitin-protein ligase XIAP
total genus 21
structure length 84
sequence length 84
chains with identical sequence C
ec nomenclature ec 2.3.2.27: RING-type E3 ubiquitin transferase.
pdb deposition date 2013-02-06

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00653 BIR Inhibitor of Apoptosis domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.1170.10 Mainly Alpha Orthogonal Bundle Inhibitor Of Apoptosis Protein (2mihbC-IAP-1); Chain A Inhibitor Of Apoptosis Protein (2mihbC-IAP-1); Chain A 4j48A00
4HY0A 5C83A 4A0IA 3M0DD 2QRAA 3UECA 3G76A 2OPZA 3UEFA 4J47A 1OXNA 3D9TA 2I3IA 3CLXA 4MU7A 3SIPE 1F3HA 1F9XA 3UEIA 3F7GA 3GTAA 1OY7A 1TFTA 3SIQA 1G73C 2JK7A 1QBHA 4J48A 3F7HA 4HY5A 4KJVA 4KMNA 2POPB 4EC4A 4KJUA 3F7IA 3UIHA 1OXQA 3UW5A 3T6PA 3UEDA 1XB0A 5C7AA 1G3FA 4LGEA 3UEGA 2POIA 2I3HA 5C7BA 3CM2A 2UVLA 4WVTA 3UIKA 4HY4A 1NW9A 4WVSA 1SDZA 2QFAA 4KMPA 3UIGA 4EB9A 4J45A 4A0NA 4J46A 3GT9A 1I3OE 3M1DA 4OXCA 4MTZA 4A0JA 5C84A 4J3YA 3UEHA 5C7DA 2OPYA 1TFQA 5C0LA 3EYLA 3UEEA 3UIIA 1M4MA 3M0AD 1SE0A 2RAWA 3MUPA 5C7CA 3CM7A 2RAXA 1C9QA 1XOXA 4WVUA 2VM5A 4MTIA 1TW6A 1JD4A 1JD6A 4LGUA 2VSLA 3UW4A 1XB1A 5C0KA 1JD5A 1Q4QA 3UIJA 1E31A 3HL5A 4J44A 5C3KA 5C3HA 3OZ1A 3D9UA
chains in the Genus database with same CATH superfamily
4HY0A 5C83A 4A0IA 3M0DD 2QRAA 3UECA 3G76A 2OPZA 3UEFA 4J47A 1OXNA 3D9TA 2I3IA 3CLXA 4MU7A 3SIPE 1F3HA 1F9XA 3UEIA 3F7GA 3GTAA 1OY7A 1TFTA 3SIQA 1G73C 2JK7A 1QBHA 4J48A 3F7HA 4HY5A 4KJVA 4KMNA 2POPB 4EC4A 4KJUA 3F7IA 3UIHA 1OXQA 3UW5A 3T6PA 3UEDA 1XB0A 5C7AA 1G3FA 4LGEA 3UEGA 2POIA 2I3HA 5C7BA 3CM2A 2UVLA 4WVTA 3UIKA 4HY4A 1NW9A 4WVSA 1SDZA 2QFAA 4KMPA 3UIGA 4EB9A 4J45A 4A0NA 4J46A 3GT9A 1I3OE 3M1DA 4OXCA 4MTZA 4A0JA 5C84A 4J3YA 3UEHA 5C7DA 2OPYA 1TFQA 5C0LA 3EYLA 3UEEA 3UIIA 1M4MA 3M0AD 1SE0A 2RAWA 3MUPA 5C7CA 3CM7A 2RAXA 1C9QA 1XOXA 4WVUA 2VM5A 4MTIA 1TW6A 1JD4A 1JD6A 4LGUA 2VSLA 3UW4A 1XB1A 5C0KA 1JD5A 1Q4QA 3UIJA 1E31A 3HL5A 4J44A 5C3KA 5C3HA 3OZ1A 3D9UA
chains in the Genus database with same CATH topology
4HY0A 5C83A 4A0IA 3M0DD 2QRAA 3UECA 3G76A 2OPZA 3UEFA 4J47A 1OXNA 3D9TA 2I3IA 3CLXA 4MU7A 3SIPE 1F3HA 1F9XA 3UEIA 3F7GA 3GTAA 1OY7A 1TFTA 3SIQA 1G73C 2JK7A 1QBHA 4J48A 3F7HA 4HY5A 4KJVA 4KMNA 2POPB 4EC4A 4KJUA 3F7IA 3UIHA 1OXQA 3UW5A 3T6PA 3UEDA 1XB0A 5C7AA 1G3FA 4LGEA 3UEGA 2POIA 2I3HA 5C7BA 3CM2A 2UVLA 4WVTA 3UIKA 4HY4A 1NW9A 4WVSA 1SDZA 2QFAA 4KMPA 3UIGA 4EB9A 4J45A 4A0NA 4J46A 3GT9A 1I3OE 3M1DA 4OXCA 4MTZA 4A0JA 5C84A 4J3YA 3UEHA 5C7DA 2OPYA 1TFQA 5C0LA 3EYLA 3UEEA 3UIIA 1M4MA 3M0AD 1SE0A 2RAWA 3MUPA 5C7CA 3CM7A 2RAXA 1C9QA 1XOXA 4WVUA 2VM5A 4MTIA 1TW6A 1JD4A 1JD6A 4LGUA 2VSLA 3UW4A 1XB1A 5C0KA 1JD5A 1Q4QA 3UIJA 1E31A 3HL5A 4J44A 5C3KA 5C3HA 3OZ1A 3D9UA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4HY0 A;  5C83 A;  4A0I A;  3M0D D;  2QRA A;  3UEC A;  3G76 A;  2OPZ A;  3UEF A;  4J47 A;  1OXN A;  3D9T A;  2I3I A;  3CLX A;  4MU7 A;  3SIP E;  1F3H A;  1F9X A;  3UEI A;  3F7G A;  3GTA A;  1OY7 A;  1TFT A;  3SIQ A;  1G73 C;  2JK7 A;  1QBH A;  4J48 A;  3F7H A;  4HY5 A;  4KJV A;  4KMN A;  2POP B;  4EC4 A;  4KJU A;  3F7I A;  3UIH A;  1OXQ A;  3UW5 A;  3T6P A;  3UED A;  1XB0 A;  5C7A A;  1G3F A;  4LGE A;  3UEG A;  2POI A;  2I3H A;  5C7B A;  3CM2 A;  2UVL A;  4WVT A;  3UIK A;  4HY4 A;  1NW9 A;  4WVS A;  1SDZ A;  2QFA A;  4KMP A;  3UIG A;  4EB9 A;  4J45 A;  4A0N A;  4J46 A;  3GT9 A;  1I3O E;  3M1D A;  4OXC A;  4MTZ A;  4A0J A;  5C84 A;  4J3Y A;  3UEH A;  5C7D A;  2OPY A;  1TFQ A;  5C0L A;  3EYL A;  3UEE A;  3UII A;  1M4M A;  3M0A D;  1SE0 A;  2RAW A;  3MUP A;  5C7C A;  3CM7 A;  2RAX A;  1C9Q A;  1XOX A;  4WVU A;  2VM5 A;  4MTI A;  1TW6 A;  1JD4 A;  1JD6 A;  4LGU A;  2VSL A;  3UW4 A;  1XB1 A;  5C0K A;  1JD5 A;  1Q4Q A;  3UIJ A;  1E31 A;  3HL5 A;  4J44 A;  5C3K A;  5C3H A;  3OZ1 A;  3D9U A; 
#chains in the Genus database with same CATH topology
 4HY0 A;  5C83 A;  4A0I A;  3M0D D;  2QRA A;  3UEC A;  3G76 A;  2OPZ A;  3UEF A;  4J47 A;  1OXN A;  3D9T A;  2I3I A;  3CLX A;  4MU7 A;  3SIP E;  1F3H A;  1F9X A;  3UEI A;  3F7G A;  3GTA A;  1OY7 A;  1TFT A;  3SIQ A;  1G73 C;  2JK7 A;  1QBH A;  4J48 A;  3F7H A;  4HY5 A;  4KJV A;  4KMN A;  2POP B;  4EC4 A;  4KJU A;  3F7I A;  3UIH A;  1OXQ A;  3UW5 A;  3T6P A;  3UED A;  1XB0 A;  5C7A A;  1G3F A;  4LGE A;  3UEG A;  2POI A;  2I3H A;  5C7B A;  3CM2 A;  2UVL A;  4WVT A;  3UIK A;  4HY4 A;  1NW9 A;  4WVS A;  1SDZ A;  2QFA A;  4KMP A;  3UIG A;  4EB9 A;  4J45 A;  4A0N A;  4J46 A;  3GT9 A;  1I3O E;  3M1D A;  4OXC A;  4MTZ A;  4A0J A;  5C84 A;  4J3Y A;  3UEH A;  5C7D A;  2OPY A;  1TFQ A;  5C0L A;  3EYL A;  3UEE A;  3UII A;  1M4M A;  3M0A D;  1SE0 A;  2RAW A;  3MUP A;  5C7C A;  3CM7 A;  2RAX A;  1C9Q A;  1XOX A;  4WVU A;  2VM5 A;  4MTI A;  1TW6 A;  1JD4 A;  1JD6 A;  4LGU A;  2VSL A;  3UW4 A;  1XB1 A;  5C0K A;  1JD5 A;  1Q4Q A;  3UIJ A;  1E31 A;  3HL5 A;  4J44 A;  5C3K A;  5C3H A;  3OZ1 A;  3D9U A; 
#chains in the Genus database with same CATH homology
 4HY0 A;  5C83 A;  4A0I A;  3M0D D;  2QRA A;  3UEC A;  3G76 A;  2OPZ A;  3UEF A;  4J47 A;  1OXN A;  3D9T A;  2I3I A;  3CLX A;  4MU7 A;  3SIP E;  1F3H A;  1F9X A;  3UEI A;  3F7G A;  3GTA A;  1OY7 A;  1TFT A;  3SIQ A;  1G73 C;  2JK7 A;  1QBH A;  4J48 A;  3F7H A;  4HY5 A;  4KJV A;  4KMN A;  2POP B;  4EC4 A;  4KJU A;  3F7I A;  3UIH A;  1OXQ A;  3UW5 A;  3T6P A;  3UED A;  1XB0 A;  5C7A A;  1G3F A;  4LGE A;  3UEG A;  2POI A;  2I3H A;  5C7B A;  3CM2 A;  2UVL A;  4WVT A;  3UIK A;  4HY4 A;  1NW9 A;  4WVS A;  1SDZ A;  2QFA A;  4KMP A;  3UIG A;  4EB9 A;  4J45 A;  4A0N A;  4J46 A;  3GT9 A;  1I3O E;  3M1D A;  4OXC A;  4MTZ A;  4A0J A;  5C84 A;  4J3Y A;  3UEH A;  5C7D A;  2OPY A;  1TFQ A;  5C0L A;  3EYL A;  3UEE A;  3UII A;  1M4M A;  3M0A D;  1SE0 A;  2RAW A;  3MUP A;  5C7C A;  3CM7 A;  2RAX A;  1C9Q A;  1XOX A;  4WVU A;  2VM5 A;  4MTI A;  1TW6 A;  1JD4 A;  1JD6 A;  4LGU A;  2VSL A;  3UW4 A;  1XB1 A;  5C0K A;  1JD5 A;  1Q4Q A;  3UIJ A;  1E31 A;  3HL5 A;  4J44 A;  5C3K A;  5C3H A;  3OZ1 A;  3D9U A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...