4OXCA

Crystal structure of xiap bir1 domain
Total Genus 22
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
22
sequence length
78
structure length
78
Chain Sequence
EFVEEFNRLKTFANFPSGSPVSASTLARAGFLYTGEGDTVRCFSCHAAVDRWQYGDSAVGRHRKVSPNCRFINGFYLE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title NF023 binding to XIAP-BIR1: Searching drugs for regulation of the NF-kappa B pathway.
pubmed doi rcsb
molecule tags Ligase
source organism Homo sapiens
molecule keywords E3 ubiquitin-protein ligase XIAP
total genus 22
structure length 78
sequence length 78
chains with identical sequence B, C, D
ec nomenclature ec 2.3.2.27: RING-type E3 ubiquitin transferase.
pdb deposition date 2014-02-05

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00653 BIR Inhibitor of Apoptosis domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.1170.10 Mainly Alpha Orthogonal Bundle Inhibitor Of Apoptosis Protein (2mihbC-IAP-1); Chain A Inhibitor Of Apoptosis Protein (2mihbC-IAP-1); Chain A 4oxcA00
1OXQA 1JD4A 1E31A 2RAWA 3SIPE 4EC4A 3M1DA 3OZ1A 1Q4QA 3UEFA 4LGEA 1XB0A 3F7HA 3UIGA 1XOXA 1G3FA 3UIIA 4J48A 4J3YA 3UEDA 2QFAA 2I3IA 2RAXA 3UEEA 3UIKA 2QRAA 5C7DA 4KMPA 5C83A 3UW4A 3T6PA 5C7AA 1JD6A 4OXCA 5C3KA 2OPZA 3D9UA 3D9TA 5C0KA 2OPYA 4A0JA 3CLXA 5C7CA 3CM7A 3UEGA 4EB9A 3F7IA 1M4MA 5C0LA 2POPB 4J44A 4KMNA 4WVSA 3EYLA 4A0IA 2JK7A 3GT9A 3SIQA 3UIHA 4HY4A 4J47A 3UW5A 5C3HA 3G76A 3GTAA 1SE0A 1QBHA 4LGUA 5C7BA 1C9QA 4MTZA 1OY7A 3M0DD 1TFQA 4WVUA 1JD5A 1TFTA 3UEIA 1TW6A 4J46A 3F7GA 2UVLA 1NW9A 4MTIA 3UECA 3UIJA 2I3HA 1SDZA 3CM2A 1G73C 2POIA 3UEHA 3MUPA 3HL5A 1OXNA 5C84A 3M0AD 4J45A 4A0NA 1F9XA 4HY5A 2VM5A 2VSLA 4WVTA 4MU7A 4HY0A 1XB1A 4KJUA 1I3OE 1F3HA 4KJVA
chains in the Genus database with same CATH superfamily
1OXQA 1JD4A 1E31A 2RAWA 3SIPE 4EC4A 3M1DA 3OZ1A 1Q4QA 3UEFA 4LGEA 1XB0A 3F7HA 3UIGA 1XOXA 1G3FA 3UIIA 4J48A 4J3YA 3UEDA 2QFAA 2I3IA 2RAXA 3UEEA 3UIKA 2QRAA 5C7DA 4KMPA 5C83A 3UW4A 3T6PA 5C7AA 1JD6A 4OXCA 5C3KA 2OPZA 3D9UA 3D9TA 5C0KA 2OPYA 4A0JA 3CLXA 5C7CA 3CM7A 3UEGA 4EB9A 3F7IA 1M4MA 5C0LA 2POPB 4J44A 4KMNA 4WVSA 3EYLA 4A0IA 2JK7A 3GT9A 3SIQA 3UIHA 4HY4A 4J47A 3UW5A 5C3HA 3G76A 3GTAA 1SE0A 1QBHA 4LGUA 5C7BA 1C9QA 4MTZA 1OY7A 3M0DD 1TFQA 4WVUA 1JD5A 1TFTA 3UEIA 1TW6A 4J46A 3F7GA 2UVLA 1NW9A 4MTIA 3UECA 3UIJA 2I3HA 1SDZA 3CM2A 1G73C 2POIA 3UEHA 3MUPA 3HL5A 1OXNA 5C84A 3M0AD 4J45A 4A0NA 1F9XA 4HY5A 2VM5A 2VSLA 4WVTA 4MU7A 4HY0A 1XB1A 4KJUA 1I3OE 1F3HA 4KJVA
chains in the Genus database with same CATH topology
1OXQA 1JD4A 1E31A 2RAWA 3SIPE 4EC4A 3M1DA 3OZ1A 1Q4QA 3UEFA 4LGEA 1XB0A 3F7HA 3UIGA 1XOXA 1G3FA 3UIIA 4J48A 4J3YA 3UEDA 2QFAA 2I3IA 2RAXA 3UEEA 3UIKA 2QRAA 5C7DA 4KMPA 5C83A 3UW4A 3T6PA 5C7AA 1JD6A 4OXCA 5C3KA 2OPZA 3D9UA 3D9TA 5C0KA 2OPYA 4A0JA 3CLXA 5C7CA 3CM7A 3UEGA 4EB9A 3F7IA 1M4MA 5C0LA 2POPB 4J44A 4KMNA 4WVSA 3EYLA 4A0IA 2JK7A 3GT9A 3SIQA 3UIHA 4HY4A 4J47A 3UW5A 5C3HA 3G76A 3GTAA 1SE0A 1QBHA 4LGUA 5C7BA 1C9QA 4MTZA 1OY7A 3M0DD 1TFQA 4WVUA 1JD5A 1TFTA 3UEIA 1TW6A 4J46A 3F7GA 2UVLA 1NW9A 4MTIA 3UECA 3UIJA 2I3HA 1SDZA 3CM2A 1G73C 2POIA 3UEHA 3MUPA 3HL5A 1OXNA 5C84A 3M0AD 4J45A 4A0NA 1F9XA 4HY5A 2VM5A 2VSLA 4WVTA 4MU7A 4HY0A 1XB1A 4KJUA 1I3OE 1F3HA 4KJVA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1OXQ A;  1JD4 A;  1E31 A;  2RAW A;  3SIP E;  4EC4 A;  3M1D A;  3OZ1 A;  1Q4Q A;  3UEF A;  4LGE A;  1XB0 A;  3F7H A;  3UIG A;  1XOX A;  1G3F A;  3UII A;  4J48 A;  4J3Y A;  3UED A;  2QFA A;  2I3I A;  2RAX A;  3UEE A;  3UIK A;  2QRA A;  5C7D A;  4KMP A;  5C83 A;  3UW4 A;  3T6P A;  5C7A A;  1JD6 A;  4OXC A;  5C3K A;  2OPZ A;  3D9U A;  3D9T A;  5C0K A;  2OPY A;  4A0J A;  3CLX A;  5C7C A;  3CM7 A;  3UEG A;  4EB9 A;  3F7I A;  1M4M A;  5C0L A;  2POP B;  4J44 A;  4KMN A;  4WVS A;  3EYL A;  4A0I A;  2JK7 A;  3GT9 A;  3SIQ A;  3UIH A;  4HY4 A;  4J47 A;  3UW5 A;  5C3H A;  3G76 A;  3GTA A;  1SE0 A;  1QBH A;  4LGU A;  5C7B A;  1C9Q A;  4MTZ A;  1OY7 A;  3M0D D;  1TFQ A;  4WVU A;  1JD5 A;  1TFT A;  3UEI A;  1TW6 A;  4J46 A;  3F7G A;  2UVL A;  1NW9 A;  4MTI A;  3UEC A;  3UIJ A;  2I3H A;  1SDZ A;  3CM2 A;  1G73 C;  2POI A;  3UEH A;  3MUP A;  3HL5 A;  1OXN A;  5C84 A;  3M0A D;  4J45 A;  4A0N A;  1F9X A;  4HY5 A;  2VM5 A;  2VSL A;  4WVT A;  4MU7 A;  4HY0 A;  1XB1 A;  4KJU A;  1I3O E;  1F3H A;  4KJV A; 
#chains in the Genus database with same CATH topology
 1OXQ A;  1JD4 A;  1E31 A;  2RAW A;  3SIP E;  4EC4 A;  3M1D A;  3OZ1 A;  1Q4Q A;  3UEF A;  4LGE A;  1XB0 A;  3F7H A;  3UIG A;  1XOX A;  1G3F A;  3UII A;  4J48 A;  4J3Y A;  3UED A;  2QFA A;  2I3I A;  2RAX A;  3UEE A;  3UIK A;  2QRA A;  5C7D A;  4KMP A;  5C83 A;  3UW4 A;  3T6P A;  5C7A A;  1JD6 A;  4OXC A;  5C3K A;  2OPZ A;  3D9U A;  3D9T A;  5C0K A;  2OPY A;  4A0J A;  3CLX A;  5C7C A;  3CM7 A;  3UEG A;  4EB9 A;  3F7I A;  1M4M A;  5C0L A;  2POP B;  4J44 A;  4KMN A;  4WVS A;  3EYL A;  4A0I A;  2JK7 A;  3GT9 A;  3SIQ A;  3UIH A;  4HY4 A;  4J47 A;  3UW5 A;  5C3H A;  3G76 A;  3GTA A;  1SE0 A;  1QBH A;  4LGU A;  5C7B A;  1C9Q A;  4MTZ A;  1OY7 A;  3M0D D;  1TFQ A;  4WVU A;  1JD5 A;  1TFT A;  3UEI A;  1TW6 A;  4J46 A;  3F7G A;  2UVL A;  1NW9 A;  4MTI A;  3UEC A;  3UIJ A;  2I3H A;  1SDZ A;  3CM2 A;  1G73 C;  2POI A;  3UEH A;  3MUP A;  3HL5 A;  1OXN A;  5C84 A;  3M0A D;  4J45 A;  4A0N A;  1F9X A;  4HY5 A;  2VM5 A;  2VSL A;  4WVT A;  4MU7 A;  4HY0 A;  1XB1 A;  4KJU A;  1I3O E;  1F3H A;  4KJV A; 
#chains in the Genus database with same CATH homology
 1OXQ A;  1JD4 A;  1E31 A;  2RAW A;  3SIP E;  4EC4 A;  3M1D A;  3OZ1 A;  1Q4Q A;  3UEF A;  4LGE A;  1XB0 A;  3F7H A;  3UIG A;  1XOX A;  1G3F A;  3UII A;  4J48 A;  4J3Y A;  3UED A;  2QFA A;  2I3I A;  2RAX A;  3UEE A;  3UIK A;  2QRA A;  5C7D A;  4KMP A;  5C83 A;  3UW4 A;  3T6P A;  5C7A A;  1JD6 A;  4OXC A;  5C3K A;  2OPZ A;  3D9U A;  3D9T A;  5C0K A;  2OPY A;  4A0J A;  3CLX A;  5C7C A;  3CM7 A;  3UEG A;  4EB9 A;  3F7I A;  1M4M A;  5C0L A;  2POP B;  4J44 A;  4KMN A;  4WVS A;  3EYL A;  4A0I A;  2JK7 A;  3GT9 A;  3SIQ A;  3UIH A;  4HY4 A;  4J47 A;  3UW5 A;  5C3H A;  3G76 A;  3GTA A;  1SE0 A;  1QBH A;  4LGU A;  5C7B A;  1C9Q A;  4MTZ A;  1OY7 A;  3M0D D;  1TFQ A;  4WVU A;  1JD5 A;  1TFT A;  3UEI A;  1TW6 A;  4J46 A;  3F7G A;  2UVL A;  1NW9 A;  4MTI A;  3UEC A;  3UIJ A;  2I3H A;  1SDZ A;  3CM2 A;  1G73 C;  2POI A;  3UEH A;  3MUP A;  3HL5 A;  1OXN A;  5C84 A;  3M0A D;  4J45 A;  4A0N A;  1F9X A;  4HY5 A;  2VM5 A;  2VSL A;  4WVT A;  4MU7 A;  4HY0 A;  1XB1 A;  4KJU A;  1I3O E;  1F3H A;  4KJV A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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