5B0HA

Crystal structure of human leukocyte cell-derived chemotaxin 2
Total Genus 33

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
33
sequence length
133
structure length
133
Chain Sequence
GPWANICAGKSSNEIRTCDRHGCGQYSAQRSQRPHQGVDVLCSAGSTVYAPFTGMIVGQEKPYQNKNAINNGVRISGRGFCVKMFYIKPIKYKGPIKKGEKLGTLLPLQKVYPGIQSHVHIENCDSSDPTAYL

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
EMPTYS4 (46-50)TI1 (7-10)S1 (18-19)TI2 (19-22)S2 (22-23)TII4 (112-115)TI3 (30-33)TI5 (123-126)TII1 (25-28)TII2 (43-46)S10 (100-105)TII3 (97-100)S5 (54-59)TIV1 (89-92)S7 (80-85)O1 (106-108)S8 (87-89)S9 (94-96)AH1 (108-111)S11 (118-123)TI4 (67-70)S3 (38-41)S6 (72-77)3H1 (130-132)Updating...
connected with : NaN
molecule tags Metal binding protein
source organism Homo sapiens
publication title Crystal Structure of Human Leukocyte Cell-derived Chemotaxin 2 (LECT2) Reveals a Mechanistic Basis of Functional Evolution in a Mammalian Protein with an M23 Metalloendopeptidase Fold
pubmed doi rcsb
molecule keywords Leukocyte cell-derived chemotaxin-2
total genus 33
structure length 133
sequence length 133
chains with identical sequence B
ec nomenclature
pdb deposition date 2015-10-29

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01551 Peptidase_M23 Peptidase family M23
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.70.70.10 Mainly Beta Distorted Sandwich Glucose Permease (Domain IIA) Glucose Permease (Domain IIA) 5b0hA00
3CSQA 4RNYA 3IT7A 1F3ZA 3TUFB 2HSIA 2B0PA 4LXCA 1GPRA 3NYYA 1F3GA 1GLEF 1AX3A 2GU1A 2F3GA 3OURB 5B0HA 5KVPA 1O2FA 1GGRA 4RNZA 4QPBA 4ZYBA 2GPRA 3UZ0B 1GLDF 4JBWM 2B13A 1GLCF 1QWYA 3SLUA 3IT5A 1GLBF 4QP5A 2B44A 1GLAF 4BH5A 2MP0B
chains in the Genus database with same CATH superfamily
3CSQA 4RNYA 3IT7A 1F3ZA 3TUFB 2HSIA 2B0PA 4LXCA 1GPRA 3NYYA 1F3GA 1GLEF 1AX3A 2GU1A 2F3GA 3OURB 5B0HA 5KVPA 1O2FA 1GGRA 4RNZA 4QPBA 4ZYBA 2GPRA 3UZ0B 1GLDF 4JBWM 2B13A 1GLCF 1QWYA 3SLUA 3IT5A 1GLBF 4QP5A 2B44A 1GLAF 4BH5A 2MP0B
chains in the Genus database with same CATH topology
3CSQA 4RNYA 3IT7A 1F3ZA 3TUFB 2HSIA 2B0PA 4LXCA 1GPRA 3NYYA 1F3GA 1GLEF 1AX3A 2GU1A 2F3GA 3OURB 5B0HA 5KVPA 1O2FA 1GGRA 4RNZA 4QPBA 4ZYBA 2GPRA 3UZ0B 1GLDF 4JBWM 2B13A 1GLCF 1QWYA 3SLUA 3IT5A 1GLBF 4QP5A 2B44A 1GLAF 4BH5A 2MP0B
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3CSQ A;  4RNY A;  3IT7 A;  1F3Z A;  3TUF B;  2HSI A;  2B0P A;  4LXC A;  1GPR A;  3NYY A;  1F3G A;  1GLE F;  1AX3 A;  2GU1 A;  2F3G A;  3OUR B;  5B0H A;  5KVP A;  1O2F A;  1GGR A;  4RNZ A;  4QPB A;  4ZYB A;  2GPR A;  3UZ0 B;  1GLD F;  4JBW M;  2B13 A;  1GLC F;  1QWY A;  3SLU A;  3IT5 A;  1GLB F;  4QP5 A;  2B44 A;  1GLA F;  4BH5 A;  2MP0 B; 
#chains in the Genus database with same CATH topology
 3CSQ A;  4RNY A;  3IT7 A;  1F3Z A;  3TUF B;  2HSI A;  2B0P A;  4LXC A;  1GPR A;  3NYY A;  1F3G A;  1GLE F;  1AX3 A;  2GU1 A;  2F3G A;  3OUR B;  5B0H A;  5KVP A;  1O2F A;  1GGR A;  4RNZ A;  4QPB A;  4ZYB A;  2GPR A;  3UZ0 B;  1GLD F;  4JBW M;  2B13 A;  1GLC F;  1QWY A;  3SLU A;  3IT5 A;  1GLB F;  4QP5 A;  2B44 A;  1GLA F;  4BH5 A;  2MP0 B; 
#chains in the Genus database with same CATH homology
 3CSQ A;  4RNY A;  3IT7 A;  1F3Z A;  3TUF B;  2HSI A;  2B0P A;  4LXC A;  1GPR A;  3NYY A;  1F3G A;  1GLE F;  1AX3 A;  2GU1 A;  2F3G A;  3OUR B;  5B0H A;  5KVP A;  1O2F A;  1GGR A;  4RNZ A;  4QPB A;  4ZYB A;  2GPR A;  3UZ0 B;  1GLD F;  4JBW M;  2B13 A;  1GLC F;  1QWY A;  3SLU A;  3IT5 A;  1GLB F;  4QP5 A;  2B44 A;  1GLA F;  4BH5 A;  2MP0 B; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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