5B0VA

Crystal structure of marburg virus vp40 dimer
Total Genus 45
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
45
sequence length
266
structure length
258
Chain Sequence
GITPNYVGDLNLDDQFKGNVCHAFTLEAIIDISNERTVKGVPAWLPLGIMSNFEYPLAHTVAALLTGSYTITQFTHNGQKFVRVNRLGTGIPAHPLRMLREGNQAFIQNMVIPRNFNQFTYNLTNLVLSVQKLPDDAWRPSKDKLIGNTMHPAVSIHPNLPPIVLPTVKKQAYRQHKNPNNGPLLAISGILHQLRVEKVPEKTSLFRISLPADMFSVKEGMMENSPVVYFQAPENFPLNGFNNRQVVLAYANPTLSAV
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal Structure of Marburg Virus VP40 Reveals a Broad, Basic Patch for Matrix Assembly and a Requirement of the N-Terminal Domain for Immunosuppression
pubmed doi rcsb
molecule keywords Matrix protein VP40
molecule tags Viral protein
source organism Lake victoria marburgvirus (strain musoke-80)
total genus 45
structure length 258
sequence length 266
chains with identical sequence B
ec nomenclature
pdb deposition date 2015-11-05

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF07447 VP40 Matrix protein VP40
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.70.20.20 Mainly Beta Distorted Sandwich Topoisomerase I; domain 3 Topoisomerase I; domain 3 5b0vA01
1ES6A 1H2CA 5B0VA 4LDMA 1H2DA 4LDDA 4LD8A 4LDBA 3TCQA
chains in the Genus database with same CATH superfamily
1CY9A 3F1JA 2VQPA 2GAIA 4G1LA 1CYYA 1CY0A 5D5HA 1MW8X 3TCQA 1CY4A 1ES6A 1MW9X 1ECLA 4RULA 4CGYA 2YKDA 4LDMA 2O5EA 1CY8A 4HI5A 4HIWA 4V23A 1CY1A 4CHTA 1H2DA 3PWTA 4LDDA 3PX7A 2O5CA 1D6MA 4LDBA 1I7DA 4G1GA 1CY6A 2GAJA 2O59A 1H2CA 4HI6A 4LP7A 5B0VA 4HIYA 4G1OA 2O54A 4HIUA 4LD8A 4HITA 2O19A 4D4TA 1CY2A 1CY7A
chains in the Genus database with same CATH topology
3F1JA 2VQPA 4G1LA 3TCQA 1ES6A 2YKDA 4LDMA 4HI5A 4HIWA 4V23A 1H2DA 4LDDA 4LDBA 4G1GA 1H2CA 4HI6A 4LP7A 5B0VA 4HIYA 4G1OA 4HIUA 4LD8A 4HITA 4D4TA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1ES6 A;  1H2C A;  5B0V A;  4LDM A;  1H2D A;  4LDD A;  4LD8 A;  4LDB A;  3TCQ A; 
#chains in the Genus database with same CATH topology
 1CY9 A;  3F1J A;  2VQP A;  2GAI A;  4G1L A;  1CYY A;  1CY0 A;  5D5H A;  1MW8 X;  3TCQ A;  1CY4 A;  1ES6 A;  1MW9 X;  1ECL A;  4RUL A;  4CGY A;  2YKD A;  4LDM A;  2O5E A;  1CY8 A;  4HI5 A;  4HIW A;  4V23 A;  1CY1 A;  4CHT A;  1H2D A;  3PWT A;  4LDD A;  3PX7 A;  2O5C A;  1D6M A;  4LDB A;  1I7D A;  4G1G A;  1CY6 A;  2GAJ A;  2O59 A;  1H2C A;  4HI6 A;  4LP7 A;  5B0V A;  4HIY A;  4G1O A;  2O54 A;  4HIU A;  4LD8 A;  4HIT A;  2O19 A;  4D4T A;  1CY2 A;  1CY7 A; 
#chains in the Genus database with same CATH homology
 3F1J A;  2VQP A;  4G1L A;  3TCQ A;  1ES6 A;  2YKD A;  4LDM A;  4HI5 A;  4HIW A;  4V23 A;  1H2D A;  4LDD A;  4LDB A;  4G1G A;  1H2C A;  4HI6 A;  4LP7 A;  5B0V A;  4HIY A;  4G1O A;  4HIU A;  4LD8 A;  4HIT A;  4D4T A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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