5B0VA

Crystal structure of marburg virus vp40 dimer
Total Genus 45
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
45
sequence length
266
structure length
258
Chain Sequence
GITPNYVGDLNLDDQFKGNVCHAFTLEAIIDISNERTVKGVPAWLPLGIMSNFEYPLAHTVAALLTGSYTITQFTHNGQKFVRVNRLGTGIPAHPLRMLREGNQAFIQNMVIPRNFNQFTYNLTNLVLSVQKLPDDAWRPSKDKLIGNTMHPAVSIHPNLPPIVLPTVKKQAYRQHKNPNNGPLLAISGILHQLRVEKVPEKTSLFRISLPADMFSVKEGMMENSPVVYFQAPENFPLNGFNNRQVVLAYANPTLSAV
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal Structure of Marburg Virus VP40 Reveals a Broad, Basic Patch for Matrix Assembly and a Requirement of the N-Terminal Domain for Immunosuppression
pubmed doi rcsb
molecule tags Viral protein
source organism Lake victoria marburgvirus (strain musoke-80)
molecule keywords Matrix protein VP40
total genus 45
structure length 258
sequence length 266
chains with identical sequence B
ec nomenclature
pdb deposition date 2015-11-05

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF07447 VP40 Matrix protein VP40
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.70.20.20 Mainly Beta Distorted Sandwich Topoisomerase I; domain 3 Topoisomerase I; domain 3 5b0vA01
4LDMA 3TCQA 1H2DA 5B0VA 4LD8A 4LDDA 1ES6A 1H2CA 4LDBA
chains in the Genus database with same CATH superfamily
1CY8A 4HI6A 4CHTA 3F1JA 4RULA 2O5CA 2GAIA 4G1GA 2O5EA 4HI5A 1CY2A 4LD8A 4LDDA 2O19A 1CY0A 4HITA 1CY6A 4LDMA 2YKDA 1I7DA 4HIUA 1MW8X 2O59A 1ES6A 1H2CA 1D6MA 2GAJA 2VQPA 4HIWA 4G1OA 4HIYA 5B0VA 3PWTA 4V23A 2O54A 1MW9X 4LDBA 3TCQA 5D5HA 1H2DA 1CY7A 4G1LA 4D4TA 1CY4A 4LP7A 1CY9A 1CYYA 4CGYA 3PX7A 1ECLA 1CY1A
chains in the Genus database with same CATH topology
4HI6A 3F1JA 4G1GA 4HI5A 4LD8A 4LDDA 4HITA 4LDMA 2YKDA 4HIUA 1ES6A 1H2CA 2VQPA 4HIWA 4G1OA 5B0VA 4V23A 4LDBA 3TCQA 1H2DA 4G1LA 4D4TA 4LP7A 4HIYA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4LDM A;  3TCQ A;  1H2D A;  5B0V A;  4LD8 A;  4LDD A;  1ES6 A;  1H2C A;  4LDB A; 
#chains in the Genus database with same CATH topology
 1CY8 A;  4HI6 A;  4CHT A;  3F1J A;  4RUL A;  2O5C A;  2GAI A;  4G1G A;  2O5E A;  4HI5 A;  1CY2 A;  4LD8 A;  4LDD A;  2O19 A;  1CY0 A;  4HIT A;  1CY6 A;  4LDM A;  2YKD A;  1I7D A;  4HIU A;  1MW8 X;  2O59 A;  1ES6 A;  1H2C A;  1D6M A;  2GAJ A;  2VQP A;  4HIW A;  4G1O A;  4HIY A;  5B0V A;  3PWT A;  4V23 A;  2O54 A;  1MW9 X;  4LDB A;  3TCQ A;  5D5H A;  1H2D A;  1CY7 A;  4G1L A;  4D4T A;  1CY4 A;  4LP7 A;  1CY9 A;  1CYY A;  4CGY A;  3PX7 A;  1ECL A;  1CY1 A; 
#chains in the Genus database with same CATH homology
 4HI6 A;  3F1J A;  4G1G A;  4HI5 A;  4LD8 A;  4LDD A;  4HIT A;  4LDM A;  2YKD A;  4HIU A;  1ES6 A;  1H2C A;  2VQP A;  4HIW A;  4G1O A;  5B0V A;  4V23 A;  4LDB A;  3TCQ A;  1H2D A;  4G1L A;  4D4T A;  4LP7 A;  4HIY A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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