5B0VA

Crystal structure of marburg virus vp40 dimer
Total Genus 45
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
45
sequence length
266
structure length
258
Chain Sequence
GITPNYVGDLNLDDQFKGNVCHAFTLEAIIDISNERTVKGVPAWLPLGIMSNFEYPLAHTVAALLTGSYTITQFTHNGQKFVRVNRLGTGIPAHPLRMLREGNQAFIQNMVIPRNFNQFTYNLTNLVLSVQKLPDDAWRPSKDKLIGNTMHPAVSIHPNLPPIVLPTVKKQAYRQHKNPNNGPLLAISGILHQLRVEKVPEKTSLFRISLPADMFSVKEGMMENSPVVYFQAPENFPLNGFNNRQVVLAYANPTLSAV
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal Structure of Marburg Virus VP40 Reveals a Broad, Basic Patch for Matrix Assembly and a Requirement of the N-Terminal Domain for Immunosuppression
pubmed doi rcsb
molecule tags Viral protein
source organism Lake victoria marburgvirus (strain musoke-80)
molecule keywords Matrix protein VP40
total genus 45
structure length 258
sequence length 266
chains with identical sequence B
ec nomenclature
pdb deposition date 2015-11-05

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF07447 VP40 Matrix protein VP40
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.70.20.20 Mainly Beta Distorted Sandwich Topoisomerase I; domain 3 Topoisomerase I; domain 3 5b0vA01
4LDBA 5B0VA 3TCQA 4LD8A 1H2DA 1H2CA 4LDDA 4LDMA 1ES6A
chains in the Genus database with same CATH superfamily
1CYYA 3PX7A 1D6MA 1ECLA 1CY6A 4G1GA 4LD8A 2GAIA 1CY0A 1CY8A 1H2DA 1ES6A 4D4TA 1CY4A 5D5HA 1MW8X 2YKDA 4RULA 4HIWA 1CY1A 3TCQA 4HI6A 4LP7A 2O59A 4CGYA 4LDMA 1CY2A 1I7DA 2O5EA 4G1LA 4V23A 5B0VA 4CHTA 1CY7A 2VQPA 4G1OA 4HI5A 2O5CA 3PWTA 4LDBA 4HITA 1CY9A 4HIUA 2O19A 2GAJA 3F1JA 1MW9X 2O54A 1H2CA 4HIYA 4LDDA
chains in the Genus database with same CATH topology
4G1GA 4LD8A 1H2DA 1ES6A 4D4TA 2YKDA 4HIWA 3TCQA 4HI6A 4LP7A 4LDMA 4G1LA 4V23A 5B0VA 2VQPA 4G1OA 4HI5A 4LDBA 4HITA 4HIUA 3F1JA 1H2CA 4HIYA 4LDDA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4LDB A;  5B0V A;  3TCQ A;  4LD8 A;  1H2D A;  1H2C A;  4LDD A;  4LDM A;  1ES6 A; 
#chains in the Genus database with same CATH topology
 1CYY A;  3PX7 A;  1D6M A;  1ECL A;  1CY6 A;  4G1G A;  4LD8 A;  2GAI A;  1CY0 A;  1CY8 A;  1H2D A;  1ES6 A;  4D4T A;  1CY4 A;  5D5H A;  1MW8 X;  2YKD A;  4RUL A;  4HIW A;  1CY1 A;  3TCQ A;  4HI6 A;  4LP7 A;  2O59 A;  4CGY A;  4LDM A;  1CY2 A;  1I7D A;  2O5E A;  4G1L A;  4V23 A;  5B0V A;  4CHT A;  1CY7 A;  2VQP A;  4G1O A;  4HI5 A;  2O5C A;  3PWT A;  4LDB A;  4HIT A;  1CY9 A;  4HIU A;  2O19 A;  2GAJ A;  3F1J A;  1MW9 X;  2O54 A;  1H2C A;  4HIY A;  4LDD A; 
#chains in the Genus database with same CATH homology
 4G1G A;  4LD8 A;  1H2D A;  1ES6 A;  4D4T A;  2YKD A;  4HIW A;  3TCQ A;  4HI6 A;  4LP7 A;  4LDM A;  4G1L A;  4V23 A;  5B0V A;  2VQP A;  4G1O A;  4HI5 A;  4LDB A;  4HIT A;  4HIU A;  3F1J A;  1H2C A;  4HIY A;  4LDD A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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