5BT2A

Mecp2 mbd domain (a140v) in complex with methylated dna
Total Genus 13
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
13
sequence length
71
structure length
71
Chain Sequence
GPMYDDPTLPEGWTRKLKQRKSGRSAGKYDVYLINPQGKAFRSKVELIVYFEKVGDTSLDPNDFDFTVTGR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title A/T Run Geometry of B-form DNA Is Independent of Bound Methyl-CpG Binding Domain, Cytosine Methylation and Flanking Sequence
doi rcsb
molecule tags Dna binding protein/dna
source organism Homo sapiens
molecule keywords Methyl-CpG-binding protein 2
total genus 13
structure length 71
sequence length 71
ec nomenclature
pdb deposition date 2015-06-02

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01429 MBD Methyl-CpG binding domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.890.10 Alpha Beta 2-Layer Sandwich Methyl-cpg-binding Protein 2; Chain A Methyl-cpg-binding Protein 2; Chain A 5bt2A01
2MOEA 3VYQA 5BT2A 3VXVA 1UB1A 3C2IA 1QK9A 2KY8A 3VXXA 1D9NA 4LG7A 3VYBA 2MB7A 1IG4A
chains in the Genus database with same CATH superfamily
2MOEA 3VYQA 5BT2A 3VXVA 1UB1A 3C2IA 1QK9A 2KY8A 3VXXA 1D9NA 4LG7A 3VYBA 2MB7A 1IG4A
chains in the Genus database with same CATH topology
2MOEA 3VYQA 5BT2A 3VXVA 1UB1A 3C2IA 1QK9A 2KY8A 3VXXA 1D9NA 4LG7A 3VYBA 2MB7A 1IG4A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2MOE A;  3VYQ A;  5BT2 A;  3VXV A;  1UB1 A;  3C2I A;  1QK9 A;  2KY8 A;  3VXX A;  1D9N A;  4LG7 A;  3VYB A;  2MB7 A;  1IG4 A; 
#chains in the Genus database with same CATH topology
 2MOE A;  3VYQ A;  5BT2 A;  3VXV A;  1UB1 A;  3C2I A;  1QK9 A;  2KY8 A;  3VXX A;  1D9N A;  4LG7 A;  3VYB A;  2MB7 A;  1IG4 A; 
#chains in the Genus database with same CATH homology
 2MOE A;  3VYQ A;  5BT2 A;  3VXV A;  1UB1 A;  3C2I A;  1QK9 A;  2KY8 A;  3VXX A;  1D9N A;  4LG7 A;  3VYB A;  2MB7 A;  1IG4 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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