1A45A

Gammaf crystallin from bovine lens
Total Genus 37
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
37
sequence length
173
structure length
173
Chain Sequence
GKITFYEDRGFQGRHYECSSDHSNLQPYFSRCNSIRVDSGCWMLYEQPNFQGPQYFLRRGDYPDYQQWMGLNDSIRSCRLIPHTGSHRLRIYEREDYRGQMVEITEDCSSLHDRFHFSEIHSFNVLEGWWVLYEMTNYRGRQYLLRPGDYRRYHDWGATNARVGSLRRAVDFY
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Towards a molecular understanding of phase separation in the lens: a comparison of the X-ray structures of two high Tc gamma-crystallins, gammaE and gammaF, with two low Tc gamma-crystallins, gammaB and gammaD.
pubmed doi rcsb
molecule tags Eye lens protein
molecule keywords GAMMAF CRYSTALLIN
total genus 37
structure length 173
sequence length 173
ec nomenclature
pdb deposition date 1998-02-10

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00030 Crystall Beta/Gamma crystallin
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.60.20.10 Mainly Beta Sandwich Gamma-B Crystallin; domain 1 Crystallins 1a45A02
2.60.20.10 Mainly Beta Sandwich Gamma-B Crystallin; domain 1 Crystallins 1a45A01
1A45A 4GCRA 1I5IA 3SO1A 4IAUA 1M8UA 1ZWMA 4GR7A 1A5DA 4PSRA 1BD7A 1PRSA 4PSPA 1E7NA 1HDFA 1PRRA 1ZIRA 1BLBA 3HZ2A 3SO0A 2BB2A 3ENTA 1ZIQA 3HZBA 1ZWOA 2V2UA 4W9BA 2G98A 2DADA 1AG4A 2K1WA 2KP5A 2M3TA 3LWKA 5HT8A 5HT9A 2KFBA 4AKAA 1ELPA 1HK0X 1ZGTA 2M3CA 2B1OA 2JDGA 1GCSA 2A5MA 4JGFA 4EL6A 2NBRA 1YHPA 3ENUA 3SNYA 1HA4A 1GAMA 1NPSA 2K1XA 3I9HA 3QK3A 4FD9A 4NI3A 1A7HA 1H4AX 3SNZA 2M3UA 1OKIA 1DSLA 2JDFA 4W9AA 1YTQA 1ZIEA 1AMMA 2BV2A 3CW3A 3IAJA
chains in the Genus database with same CATH superfamily
3SO1A 4IAUA 4PSPA 1PRSA 1ZIRA 1HDFA 1PRRA 3HZ2A 1ZIQA 3HZBA 2K1WA 5HT9A 5HT8A 1ZGTA 1G6EA 2B1OA 4EL6A 4JGFA 1F53A 2NBRA 3ENUA 3SNYA 2K1XA 4FD9A 2M3UA 1YTQA 1ZIEA 2BV2A 1A45A 1I5IA 4PSRA 1A5DA 1BD7A 1ZWOA 2V2UA 2KP5A 2M3TA 1GH5A 2KFBA 4AKAA 1ELPA 2JDGA 1GCSA 2A5MA 1YHPA 1NPSA 1H4AX 1DSLA 2JDFA 1AMMA 3IAJA 4GCRA 4GR7A 3SO0A 1BLBA 2DADA 1AG4A 3LWKA 1HK0X 3UJZA 3QK3A 3I9HA 1A7HA 1C01A 1M8UA 1ZWMA 1E7NA 2BB2A 3ENTA 4W9BA 2G98A 2M3CA 1BHUA 1WKTA 1HA4A 1GAMA 4NI3A 3SNZA 1OKIA 4W9AA 3CW3A
chains in the Genus database with same CATH topology
1A45A 4GCRA 1I5IA 3SO1A 4IAUA 1M8UA 1ZWMA 4GR7A 1A5DA 4PSRA 1BD7A 1PRSA 4PSPA 1E7NA 1HDFA 1PRRA 1ZIRA 1BLBA 3HZ2A 3SO0A 2BB2A 3ENTA 1ZIQA 3HZBA 1ZWOA 2V2UA 4W9BA 2G98A 2DADA 1AG4A 2K1WA 2KP5A 2M3TA 3LWKA 5HT8A 5HT9A 2KFBA 4AKAA 1ELPA 1HK0X 1ZGTA 2M3CA 2B1OA 2JDGA 1GCSA 2A5MA 4JGFA 4EL6A 2NBRA 1YHPA 3ENUA 3SNYA 1HA4A 1GAMA 1NPSA 2K1XA 3I9HA 3QK3A 4FD9A 4NI3A 1A7HA 1H4AX 3SNZA 2M3UA 1OKIA 1DSLA 2JDFA 4W9AA 1YTQA 1ZIEA 1AMMA 2BV2A 3CW3A 3IAJA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1A45 A;  4GCR A;  1I5I A;  3SO1 A;  4IAU A;  1M8U A;  1ZWM A;  4GR7 A;  1A5D A;  4PSR A;  1BD7 A;  1PRS A;  4PSP A;  1E7N A;  1HDF A;  1PRR A;  1ZIR A;  1BLB A;  3HZ2 A;  3SO0 A;  2BB2 A;  3ENT A;  1ZIQ A;  3HZB A;  1ZWO A;  2V2U A;  4W9B A;  2G98 A;  2DAD A;  1AG4 A;  2K1W A;  2KP5 A;  2M3T A;  3LWK A;  5HT8 A;  5HT9 A;  2KFB A;  4AKA A;  1ELP A;  1HK0 X;  1ZGT A;  2M3C A;  2B1O A;  2JDG A;  1GCS A;  2A5M A;  4JGF A;  4EL6 A;  2NBR A;  1YHP A;  3ENU A;  3SNY A;  1HA4 A;  1GAM A;  1NPS A;  2K1X A;  3I9H A;  3QK3 A;  4FD9 A;  4NI3 A;  1A7H A;  1H4A X;  3SNZ A;  2M3U A;  1OKI A;  1DSL A;  2JDF A;  4W9A A;  1YTQ A;  1ZIE A;  1AMM A;  2BV2 A;  3CW3 A;  3IAJ A; 
#chains in the Genus database with same CATH topology
 3SO1 A;  4IAU A;  4PSP A;  1PRS A;  1ZIR A;  1HDF A;  1PRR A;  3HZ2 A;  1ZIQ A;  3HZB A;  2K1W A;  5HT9 A;  5HT8 A;  1ZGT A;  1G6E A;  2B1O A;  4EL6 A;  4JGF A;  1F53 A;  2NBR A;  3ENU A;  3SNY A;  2K1X A;  4FD9 A;  2M3U A;  1YTQ A;  1ZIE A;  2BV2 A;  1A45 A;  1I5I A;  4PSR A;  1A5D A;  1BD7 A;  1ZWO A;  2V2U A;  2KP5 A;  2M3T A;  1GH5 A;  2KFB A;  4AKA A;  1ELP A;  2JDG A;  1GCS A;  2A5M A;  1YHP A;  1NPS A;  1H4A X;  1DSL A;  2JDF A;  1AMM A;  3IAJ A;  4GCR A;  4GR7 A;  3SO0 A;  1BLB A;  2DAD A;  1AG4 A;  3LWK A;  1HK0 X;  3UJZ A;  3QK3 A;  3I9H A;  1A7H A;  1C01 A;  1M8U A;  1ZWM A;  1E7N A;  2BB2 A;  3ENT A;  4W9B A;  2G98 A;  2M3C A;  1BHU A;  1WKT A;  1HA4 A;  1GAM A;  4NI3 A;  3SNZ A;  1OKI A;  4W9A A;  3CW3 A; 
#chains in the Genus database with same CATH homology
 1A45 A;  4GCR A;  1I5I A;  3SO1 A;  4IAU A;  1M8U A;  1ZWM A;  4GR7 A;  1A5D A;  4PSR A;  1BD7 A;  1PRS A;  4PSP A;  1E7N A;  1HDF A;  1PRR A;  1ZIR A;  1BLB A;  3HZ2 A;  3SO0 A;  2BB2 A;  3ENT A;  1ZIQ A;  3HZB A;  1ZWO A;  2V2U A;  4W9B A;  2G98 A;  2DAD A;  1AG4 A;  2K1W A;  2KP5 A;  2M3T A;  3LWK A;  5HT8 A;  5HT9 A;  2KFB A;  4AKA A;  1ELP A;  1HK0 X;  1ZGT A;  2M3C A;  2B1O A;  2JDG A;  1GCS A;  2A5M A;  4JGF A;  4EL6 A;  2NBR A;  1YHP A;  3ENU A;  3SNY A;  1HA4 A;  1GAM A;  1NPS A;  2K1X A;  3I9H A;  3QK3 A;  4FD9 A;  4NI3 A;  1A7H A;  1H4A X;  3SNZ A;  2M3U A;  1OKI A;  1DSL A;  2JDF A;  4W9A A;  1YTQ A;  1ZIE A;  1AMM A;  2BV2 A;  3CW3 A;  3IAJ A; 
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