1A5DA

Gammae crystallin from rat lens
Total Genus 42
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
42
sequence length
173
structure length
173
Chain Sequence
GKITFYEDRGFQGRHYECSTDHSNLQPYFSRCNSVRVDSGCWMLYEQPNFTGCQYFLRRGDYPDYQQWMGFSDSVRSCRLIPHSSSHRIRIYEREDYRGQMVEITDDCPHLQDRFHFSDFHSFHVMEGYWVLYEMPNYRGRQYLLRPGEYRRYHDWGAMNARVGSLRRIMDFY
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Towards a molecular understanding of phase separation in the lens: a comparison of the X-ray structures of two high Tc gamma-crystallins, gammaE and gammaF, with two low Tc gamma-crystallins, gammaB and gammaD.
pubmed doi rcsb
molecule tags Eye lens protein
molecule keywords GAMMAE CRYSTALLIN
total genus 42
structure length 173
sequence length 173
chains with identical sequence B
ec nomenclature
pdb deposition date 1998-02-12

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00030 Crystall Beta/Gamma crystallin
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.60.20.10 Mainly Beta Sandwich Gamma-B Crystallin; domain 1 Crystallins 1a5dA02
2.60.20.10 Mainly Beta Sandwich Gamma-B Crystallin; domain 1 Crystallins 1a5dA01
1A7HA 1E7NA 1ELPA 1OKIA 2G98A 2JDGA 4JGFA 4PSPA 1A45A 1ZWOA 1YHPA 2B1OA 1ZIEA 2JDFA 3HZBA 4PSRA 1NPSA 2M3UA 1A5DA 1ZIRA 2KFBA 3HZ2A 3CW3A 4W9AA 1YTQA 2A5MA 1H4AX 1PRRA 2BB2A 2K1WA 3ENTA 5HT8A 2KP5A 1BLBA 1BD7A 2M3CA 1AMMA 1ZWMA 3LWKA 1M8UA 2K1XA 1AG4A 3I9HA 4GR7A 3SO1A 1PRSA 1DSLA 2NBRA 3QK3A 3SNZA 1I5IA 1ZGTA 1HDFA 4EL6A 1GAMA 1HA4A 4NI3A 2DADA 4AKAA 5HT9A 2BV2A 2V2UA 3IAJA 4FD9A 4W9BA 2M3TA 3SNYA 3SO0A 1GCSA 1HK0X 4GCRA 1ZIQA 3ENUA 4IAUA
chains in the Genus database with same CATH superfamily
1OKIA 1ZIEA 3HZ2A 2KFBA 2BB2A 1H4AX 3LWKA 1PRSA 1I5IA 3UJZA 1HDFA 2DADA 4AKAA 2BV2A 2V2UA 4GCRA 1ZIQA 4IAUA 1A7HA 1G6EA 2JDGA 2JDFA 4W9AA 2A5MA 1PRRA 2K1WA 1AG4A 1ZGTA 4EL6A 1HA4A 4NI3A 1F53A 1GH5A 5HT9A 2M3TA 3ENUA 1ELPA 1E7NA 1BHUA 4JGFA 4PSPA 1A45A 2B1OA 4PSRA 1NPSA 1ZIRA 5HT8A 2M3CA 1AMMA 2K1XA 4GR7A 3QK3A 1C01A 3SNZA 4W9BA 2G98A 1ZWOA 1YHPA 3HZBA 2M3UA 1A5DA 3CW3A 1YTQA 3ENTA 2KP5A 1BLBA 1BD7A 1ZWMA 1M8UA 3I9HA 3SO1A 1DSLA 2NBRA 1GAMA 1WKTA 3IAJA 4FD9A 3SNYA 3SO0A 1GCSA 1HK0X
chains in the Genus database with same CATH topology
1A7HA 1E7NA 1ELPA 1OKIA 2G98A 2JDGA 4JGFA 4PSPA 1A45A 1ZWOA 1YHPA 2B1OA 1ZIEA 2JDFA 3HZBA 4PSRA 1NPSA 2M3UA 1A5DA 1ZIRA 2KFBA 3HZ2A 3CW3A 4W9AA 1YTQA 2A5MA 1H4AX 1PRRA 2BB2A 2K1WA 3ENTA 5HT8A 2KP5A 1BLBA 1BD7A 2M3CA 1AMMA 1ZWMA 3LWKA 1M8UA 2K1XA 1AG4A 3I9HA 4GR7A 3SO1A 1PRSA 1DSLA 2NBRA 3QK3A 3SNZA 1I5IA 1ZGTA 1HDFA 4EL6A 1GAMA 1HA4A 4NI3A 2DADA 4AKAA 5HT9A 2BV2A 2V2UA 3IAJA 4FD9A 4W9BA 2M3TA 3SNYA 3SO0A 1GCSA 1HK0X 4GCRA 1ZIQA 3ENUA 4IAUA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1A7H A;  1E7N A;  1ELP A;  1OKI A;  2G98 A;  2JDG A;  4JGF A;  4PSP A;  1A45 A;  1ZWO A;  1YHP A;  2B1O A;  1ZIE A;  2JDF A;  3HZB A;  4PSR A;  1NPS A;  2M3U A;  1A5D A;  1ZIR A;  2KFB A;  3HZ2 A;  3CW3 A;  4W9A A;  1YTQ A;  2A5M A;  1H4A X;  1PRR A;  2BB2 A;  2K1W A;  3ENT A;  5HT8 A;  2KP5 A;  1BLB A;  1BD7 A;  2M3C A;  1AMM A;  1ZWM A;  3LWK A;  1M8U A;  2K1X A;  1AG4 A;  3I9H A;  4GR7 A;  3SO1 A;  1PRS A;  1DSL A;  2NBR A;  3QK3 A;  3SNZ A;  1I5I A;  1ZGT A;  1HDF A;  4EL6 A;  1GAM A;  1HA4 A;  4NI3 A;  2DAD A;  4AKA A;  5HT9 A;  2BV2 A;  2V2U A;  3IAJ A;  4FD9 A;  4W9B A;  2M3T A;  3SNY A;  3SO0 A;  1GCS A;  1HK0 X;  4GCR A;  1ZIQ A;  3ENU A;  4IAU A; 
#chains in the Genus database with same CATH topology
 1OKI A;  1ZIE A;  3HZ2 A;  2KFB A;  2BB2 A;  1H4A X;  3LWK A;  1PRS A;  1I5I A;  3UJZ A;  1HDF A;  2DAD A;  4AKA A;  2BV2 A;  2V2U A;  4GCR A;  1ZIQ A;  4IAU A;  1A7H A;  1G6E A;  2JDG A;  2JDF A;  4W9A A;  2A5M A;  1PRR A;  2K1W A;  1AG4 A;  1ZGT A;  4EL6 A;  1HA4 A;  4NI3 A;  1F53 A;  1GH5 A;  5HT9 A;  2M3T A;  3ENU A;  1ELP A;  1E7N A;  1BHU A;  4JGF A;  4PSP A;  1A45 A;  2B1O A;  4PSR A;  1NPS A;  1ZIR A;  5HT8 A;  2M3C A;  1AMM A;  2K1X A;  4GR7 A;  3QK3 A;  1C01 A;  3SNZ A;  4W9B A;  2G98 A;  1ZWO A;  1YHP A;  3HZB A;  2M3U A;  1A5D A;  3CW3 A;  1YTQ A;  3ENT A;  2KP5 A;  1BLB A;  1BD7 A;  1ZWM A;  1M8U A;  3I9H A;  3SO1 A;  1DSL A;  2NBR A;  1GAM A;  1WKT A;  3IAJ A;  4FD9 A;  3SNY A;  3SO0 A;  1GCS A;  1HK0 X; 
#chains in the Genus database with same CATH homology
 1A7H A;  1E7N A;  1ELP A;  1OKI A;  2G98 A;  2JDG A;  4JGF A;  4PSP A;  1A45 A;  1ZWO A;  1YHP A;  2B1O A;  1ZIE A;  2JDF A;  3HZB A;  4PSR A;  1NPS A;  2M3U A;  1A5D A;  1ZIR A;  2KFB A;  3HZ2 A;  3CW3 A;  4W9A A;  1YTQ A;  2A5M A;  1H4A X;  1PRR A;  2BB2 A;  2K1W A;  3ENT A;  5HT8 A;  2KP5 A;  1BLB A;  1BD7 A;  2M3C A;  1AMM A;  1ZWM A;  3LWK A;  1M8U A;  2K1X A;  1AG4 A;  3I9H A;  4GR7 A;  3SO1 A;  1PRS A;  1DSL A;  2NBR A;  3QK3 A;  3SNZ A;  1I5I A;  1ZGT A;  1HDF A;  4EL6 A;  1GAM A;  1HA4 A;  4NI3 A;  2DAD A;  4AKA A;  5HT9 A;  2BV2 A;  2V2U A;  3IAJ A;  4FD9 A;  4W9B A;  2M3T A;  3SNY A;  3SO0 A;  1GCS A;  1HK0 X;  4GCR A;  1ZIQ A;  3ENU A;  4IAU A; 
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