1E7NA

The n-terminal domain of beta-b2-crystallin resembles the putative ancestral homodimer
Total Genus 16
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
16
sequence length
89
structure length
89
Chain Sequence
LNPKIIIFEQENFQGHSHELSGPCPNLKETGMEKAGSVLVQAGPWVGYEQANCKGEQFVFEKGEYPRWDSWTSSRRTDSLSSLRPIKVD
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title The N-Terminal Domain of Betab2-Crystallin Resembles the Putative Ancestral Homodimer.
pubmed doi rcsb
molecule tags Structural protein
source organism Mus musculus
molecule keywords BETA-CRYSTALLIN B2
total genus 16
structure length 89
sequence length 89
chains with identical sequence B
ec nomenclature
pdb deposition date 2000-08-31

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00030 Crystall Beta/Gamma crystallin
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.60.20.10 Mainly Beta Sandwich Gamma-B Crystallin; domain 1 Crystallins 1e7nA00
1I5IA 4W9AA 5HT8A 2K1WA 1HA4A 1PRSA 1YHPA 2BB2A 2K1XA 3HZBA 4JGFA 4AKAA 3ENUA 1DSLA 1ZWMA 1YTQA 3CW3A 2M3TA 4GR7A 4PSPA 3SNZA 3LWKA 4NI3A 2M3CA 4EL6A 1ZIEA 2JDGA 1AG4A 1NPSA 1HK0X 3IAJA 1BLBA 1PRRA 1ZIRA 1A45A 2KP5A 4FD9A 4PSRA 4W9BA 2BV2A 2B1OA 2DADA 3ENTA 5HT9A 4IAUA 1BD7A 3QK3A 1M8UA 1A7HA 1H4AX 1E7NA 1OKIA 2NBRA 1A5DA 1ZIQA 2KFBA 3SNYA 1GAMA 2A5MA 1HDFA 1ZGTA 3SO1A 2JDFA 1ZWOA 4GCRA 1AMMA 3I9HA 2G98A 3SO0A 2M3UA 3HZ2A 1ELPA 1GCSA 2V2UA
chains in the Genus database with same CATH superfamily
1I5IA 1YHPA 3HZBA 1ZIEA 1BLBA 3ENTA 1M8UA 3UJZA 1WKTA 1HDFA 1ZWOA 4GCRA 1AMMA 2V2UA 1HA4A 1PRSA 2BB2A 2K1XA 4AKAA 4GR7A 1YTQA 4PSPA 3LWKA 4W9BA 1G6EA 2KP5A 2BV2A 2DADA 3QK3A 1A7HA 1H4AX 1GH5A 1OKIA 2NBRA 2JDFA 3I9HA 3SO0A 1C01A 2M3UA 3HZ2A 2G98A 1GCSA 2K1WA 4JGFA 3ENUA 1DSLA 1ZWMA 3CW3A 2M3TA 3SNZA 4NI3A 2M3CA 1AG4A 1BHUA 1ZIRA 4FD9A 5HT9A 4IAUA 1E7NA 1F53A 1A5DA 5HT8A 4W9AA 4EL6A 2JDGA 1NPSA 1HK0X 3IAJA 1PRRA 4PSRA 1A45A 2B1OA 1BD7A 1ZIQA 2KFBA 3SNYA 1GAMA 2A5MA 1ZGTA 3SO1A 1ELPA
chains in the Genus database with same CATH topology
1I5IA 4W9AA 5HT8A 2K1WA 1HA4A 1PRSA 1YHPA 2BB2A 2K1XA 3HZBA 4JGFA 4AKAA 3ENUA 1DSLA 1ZWMA 1YTQA 3CW3A 2M3TA 4GR7A 4PSPA 3SNZA 3LWKA 4NI3A 2M3CA 4EL6A 1ZIEA 2JDGA 1AG4A 1NPSA 1HK0X 3IAJA 1BLBA 1PRRA 1ZIRA 1A45A 2KP5A 4FD9A 4PSRA 4W9BA 2BV2A 2B1OA 2DADA 3ENTA 5HT9A 4IAUA 1BD7A 3QK3A 1M8UA 1A7HA 1H4AX 1E7NA 1OKIA 2NBRA 1A5DA 1ZIQA 2KFBA 3SNYA 1GAMA 2A5MA 1HDFA 1ZGTA 3SO1A 2JDFA 1ZWOA 4GCRA 1AMMA 3I9HA 2G98A 3SO0A 2M3UA 3HZ2A 1ELPA 1GCSA 2V2UA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1I5I A;  4W9A A;  5HT8 A;  2K1W A;  1HA4 A;  1PRS A;  1YHP A;  2BB2 A;  2K1X A;  3HZB A;  4JGF A;  4AKA A;  3ENU A;  1DSL A;  1ZWM A;  1YTQ A;  3CW3 A;  2M3T A;  4GR7 A;  4PSP A;  3SNZ A;  3LWK A;  4NI3 A;  2M3C A;  4EL6 A;  1ZIE A;  2JDG A;  1AG4 A;  1NPS A;  1HK0 X;  3IAJ A;  1BLB A;  1PRR A;  1ZIR A;  1A45 A;  2KP5 A;  4FD9 A;  4PSR A;  4W9B A;  2BV2 A;  2B1O A;  2DAD A;  3ENT A;  5HT9 A;  4IAU A;  1BD7 A;  3QK3 A;  1M8U A;  1A7H A;  1H4A X;  1E7N A;  1OKI A;  2NBR A;  1A5D A;  1ZIQ A;  2KFB A;  3SNY A;  1GAM A;  2A5M A;  1HDF A;  1ZGT A;  3SO1 A;  2JDF A;  1ZWO A;  4GCR A;  1AMM A;  3I9H A;  2G98 A;  3SO0 A;  2M3U A;  3HZ2 A;  1ELP A;  1GCS A;  2V2U A; 
#chains in the Genus database with same CATH topology
 1I5I A;  1YHP A;  3HZB A;  1ZIE A;  1BLB A;  3ENT A;  1M8U A;  3UJZ A;  1WKT A;  1HDF A;  1ZWO A;  4GCR A;  1AMM A;  2V2U A;  1HA4 A;  1PRS A;  2BB2 A;  2K1X A;  4AKA A;  4GR7 A;  1YTQ A;  4PSP A;  3LWK A;  4W9B A;  1G6E A;  2KP5 A;  2BV2 A;  2DAD A;  3QK3 A;  1A7H A;  1H4A X;  1GH5 A;  1OKI A;  2NBR A;  2JDF A;  3I9H A;  3SO0 A;  1C01 A;  2M3U A;  3HZ2 A;  2G98 A;  1GCS A;  2K1W A;  4JGF A;  3ENU A;  1DSL A;  1ZWM A;  3CW3 A;  2M3T A;  3SNZ A;  4NI3 A;  2M3C A;  1AG4 A;  1BHU A;  1ZIR A;  4FD9 A;  5HT9 A;  4IAU A;  1E7N A;  1F53 A;  1A5D A;  5HT8 A;  4W9A A;  4EL6 A;  2JDG A;  1NPS A;  1HK0 X;  3IAJ A;  1PRR A;  4PSR A;  1A45 A;  2B1O A;  1BD7 A;  1ZIQ A;  2KFB A;  3SNY A;  1GAM A;  2A5M A;  1ZGT A;  3SO1 A;  1ELP A; 
#chains in the Genus database with same CATH homology
 1I5I A;  4W9A A;  5HT8 A;  2K1W A;  1HA4 A;  1PRS A;  1YHP A;  2BB2 A;  2K1X A;  3HZB A;  4JGF A;  4AKA A;  3ENU A;  1DSL A;  1ZWM A;  1YTQ A;  3CW3 A;  2M3T A;  4GR7 A;  4PSP A;  3SNZ A;  3LWK A;  4NI3 A;  2M3C A;  4EL6 A;  1ZIE A;  2JDG A;  1AG4 A;  1NPS A;  1HK0 X;  3IAJ A;  1BLB A;  1PRR A;  1ZIR A;  1A45 A;  2KP5 A;  4FD9 A;  4PSR A;  4W9B A;  2BV2 A;  2B1O A;  2DAD A;  3ENT A;  5HT9 A;  4IAU A;  1BD7 A;  3QK3 A;  1M8U A;  1A7H A;  1H4A X;  1E7N A;  1OKI A;  2NBR A;  1A5D A;  1ZIQ A;  2KFB A;  3SNY A;  1GAM A;  2A5M A;  1HDF A;  1ZGT A;  3SO1 A;  2JDF A;  1ZWO A;  4GCR A;  1AMM A;  3I9H A;  2G98 A;  3SO0 A;  2M3U A;  3HZ2 A;  1ELP A;  1GCS A;  2V2U A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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