1F5VA

Structure and site-directed mutagenesis of a flavoprotein from escherichia coli that reduces nitrocompounds. alteration of pyridine nucleotide binding by a single amino acid substitution
Total Genus 77
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
77
sequence length
240
structure length
240
Chain Sequence
MTPTIELICGHRSIRHFTDEPISEAQREAIINSARATSSSSFLQCSSIIRITDKALREELVTLTGGQKHVAQAAEFWVFCADFNRHLQICPDAQLGLAEQLLLGVVDTAMMAQNALIAAESLGLGGVYIGGLRNNIEAVTKLLKLPQHVLPLFGLCLGWPADNPDLKPRLPASILVHENSYQPLDKGALAQYDEQLAEYYLTRGSNNRRDTWSDHIRRTIIKESRPFILDYLHKQGWATR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Oxidoreductase
source organism Escherichia coli
publication title Structure and site-directed mutagenesis of a flavoprotein from Escherichia coli that reduces nitrocompounds: alteration of pyridine nucleotide binding by a single amino acid substitution.
pubmed doi rcsb
molecule keywords OXYGEN-INSENSITIVE NADPH NITROREDUCTASE
total genus 77
structure length 240
sequence length 240
chains with identical sequence B
ec nomenclature ec 1.6.99.6: Transferred entry: 1.6.5.10.
pdb deposition date 2000-06-17

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00881 Nitroreductase Nitroreductase family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.109.10 Alpha Beta 3-Layer(aba) Sandwich NADH Oxidase NADH Oxidase 1f5vA00
4XOOA 3EOFA 4G8SA 3EK3A 4TTBA 3GBHA 3GE5A 3TNZA 1IDTA 3GFDA 3TO0A 3EO7A 4QLYA 4EO3A 1YKIA 3HJ9A 1KQBA 3E39A 2H0UA 1BKJA 2HAYA 2I7HA 3OF4A 5KO7A 4BN9A 1OONA 1KQDA 4XOQA 3E10A 4BN6A 1F5VA 4BN8A 1V5ZA 1KQCA 3BM2A 3GH8A 2BKJA 1YLUA 3HOIA 2ISJA 2WZVA 3BEMA 3H4OA 1OO6A 1NOXA 2WQFA 4BN7A 4BNBA 3G14A 1OOQA 5KO8A 5KRDA 1ICRA 3GB5A 3QDLA 4XOMA 3BM1A 3PXVA 3N2SA 4TTCA 1VFRA 5HEIA 1ICUA 4QLXA 3GFAA 1ICVA 2ISKA 2WZWA 5J6CA 2YMVA 1VKWA 2R01A 3M5KA 3GAGA 4URPA 3GR3A 1OO5A 2IFAA 1YWQA 1ZCHA 1V5YA 2FREA 3EO8A 1YLRA 3X22A 2B67A 3X21A 3KWKA 2ISLA 4DN2A 1DS7A 3K6HA 1NECA 3GE6A 3HZNA 5HDJA 3KOQA
chains in the Genus database with same CATH superfamily
4XOOA 3EOFA 4G8SA 3EK3A 4TTBA 3GBHA 3GE5A 3TNZA 1IDTA 3GFDA 3TO0A 3EO7A 4QLYA 4EO3A 1YKIA 3HJ9A 1KQBA 3E39A 2H0UA 1BKJA 2HAYA 2I7HA 3OF4A 5KO7A 4BN9A 1OONA 1KQDA 4XOQA 3E10A 4BN6A 1F5VA 4BN8A 1V5ZA 1KQCA 3BM2A 3GH8A 2BKJA 1YLUA 3HOIA 2ISJA 2WZVA 3BEMA 3H4OA 1OO6A 1NOXA 2WQFA 4BN7A 4BNBA 3G14A 1OOQA 5KO8A 5KRDA 1ICRA 3GB5A 3QDLA 4XOMA 3BM1A 1J6RA 3PXVA 3N2SA 4TTCA 1VFRA 5HEIA 1ICUA 4QLXA 3GFAA 1ICVA 2ISKA 2WZWA 5J6CA 2YMVA 1VKWA 2R01A 3M5KA 3GAGA 4URPA 3GR3A 1OO5A 2IFAA 1YWQA 1ZCHA 1V5YA 2FREA 3EO8A 1YLRA 3X22A 2B67A 3X21A 3KWKA 2ISLA 4DN2A 1DS7A 3K6HA 1NECA 3GE6A 3HZNA 5HDJA 3KOQA
chains in the Genus database with same CATH topology
4XOOA 3EOFA 4G8SA 3EK3A 4TTBA 3GBHA 3GE5A 3TNZA 1IDTA 3GFDA 3TO0A 3EO7A 4QLYA 4EO3A 1YKIA 3HJ9A 1KQBA 3E39A 2H0UA 1BKJA 2HAYA 2I7HA 3OF4A 5KO7A 4BN9A 1OONA 1KQDA 4XOQA 3E10A 4BN6A 1F5VA 4BN8A 1V5ZA 1KQCA 3BM2A 3GH8A 2BKJA 1YLUA 3HOIA 2ISJA 2WZVA 3BEMA 3H4OA 1OO6A 1NOXA 2WQFA 4BN7A 4BNBA 3G14A 1OOQA 5KO8A 5KRDA 1ICRA 3GB5A 3QDLA 4XOMA 3BM1A 1J6RA 3PXVA 3N2SA 4TTCA 1VFRA 5HEIA 1ICUA 4QLXA 3GFAA 1ICVA 2ISKA 2WZWA 5J6CA 2YMVA 1VKWA 2R01A 3M5KA 3GAGA 4URPA 3GR3A 1OO5A 2IFAA 1YWQA 1ZCHA 1V5YA 2FREA 3EO8A 1YLRA 3X22A 2B67A 3X21A 3KWKA 2ISLA 4DN2A 1DS7A 3K6HA 1NECA 3GE6A 3HZNA 5HDJA 3KOQA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4XOO A;  3EOF A;  4G8S A;  3EK3 A;  4TTB A;  3GBH A;  3GE5 A;  3TNZ A;  1IDT A;  3GFD A;  3TO0 A;  3EO7 A;  4QLY A;  4EO3 A;  1YKI A;  3HJ9 A;  1KQB A;  3E39 A;  2H0U A;  1BKJ A;  2HAY A;  2I7H A;  3OF4 A;  5KO7 A;  4BN9 A;  1OON A;  1KQD A;  4XOQ A;  3E10 A;  4BN6 A;  1F5V A;  4BN8 A;  1V5Z A;  1KQC A;  3BM2 A;  3GH8 A;  2BKJ A;  1YLU A;  3HOI A;  2ISJ A;  2WZV A;  3BEM A;  3H4O A;  1OO6 A;  1NOX A;  2WQF A;  4BN7 A;  4BNB A;  3G14 A;  1OOQ A;  5KO8 A;  5KRD A;  1ICR A;  3GB5 A;  3QDL A;  4XOM A;  3BM1 A;  3PXV A;  3N2S A;  4TTC A;  1VFR A;  5HEI A;  1ICU A;  4QLX A;  3GFA A;  1ICV A;  2ISK A;  2WZW A;  5J6C A;  2YMV A;  1VKW A;  2R01 A;  3M5K A;  3GAG A;  4URP A;  3GR3 A;  1OO5 A;  2IFA A;  1YWQ A;  1ZCH A;  1V5Y A;  2FRE A;  3EO8 A;  1YLR A;  3X22 A;  2B67 A;  3X21 A;  3KWK A;  2ISL A;  4DN2 A;  1DS7 A;  3K6H A;  1NEC A;  3GE6 A;  3HZN A;  5HDJ A;  3KOQ A; 
#chains in the Genus database with same CATH topology
 4XOO A;  3EOF A;  4G8S A;  3EK3 A;  4TTB A;  3GBH A;  3GE5 A;  3TNZ A;  1IDT A;  3GFD A;  3TO0 A;  3EO7 A;  4QLY A;  4EO3 A;  1YKI A;  3HJ9 A;  1KQB A;  3E39 A;  2H0U A;  1BKJ A;  2HAY A;  2I7H A;  3OF4 A;  5KO7 A;  4BN9 A;  1OON A;  1KQD A;  4XOQ A;  3E10 A;  4BN6 A;  1F5V A;  4BN8 A;  1V5Z A;  1KQC A;  3BM2 A;  3GH8 A;  2BKJ A;  1YLU A;  3HOI A;  2ISJ A;  2WZV A;  3BEM A;  3H4O A;  1OO6 A;  1NOX A;  2WQF A;  4BN7 A;  4BNB A;  3G14 A;  1OOQ A;  5KO8 A;  5KRD A;  1ICR A;  3GB5 A;  3QDL A;  4XOM A;  3BM1 A;  1J6R A;  3PXV A;  3N2S A;  4TTC A;  1VFR A;  5HEI A;  1ICU A;  4QLX A;  3GFA A;  1ICV A;  2ISK A;  2WZW A;  5J6C A;  2YMV A;  1VKW A;  2R01 A;  3M5K A;  3GAG A;  4URP A;  3GR3 A;  1OO5 A;  2IFA A;  1YWQ A;  1ZCH A;  1V5Y A;  2FRE A;  3EO8 A;  1YLR A;  3X22 A;  2B67 A;  3X21 A;  3KWK A;  2ISL A;  4DN2 A;  1DS7 A;  3K6H A;  1NEC A;  3GE6 A;  3HZN A;  5HDJ A;  3KOQ A; 
#chains in the Genus database with same CATH homology
 4XOO A;  3EOF A;  4G8S A;  3EK3 A;  4TTB A;  3GBH A;  3GE5 A;  3TNZ A;  1IDT A;  3GFD A;  3TO0 A;  3EO7 A;  4QLY A;  4EO3 A;  1YKI A;  3HJ9 A;  1KQB A;  3E39 A;  2H0U A;  1BKJ A;  2HAY A;  2I7H A;  3OF4 A;  5KO7 A;  4BN9 A;  1OON A;  1KQD A;  4XOQ A;  3E10 A;  4BN6 A;  1F5V A;  4BN8 A;  1V5Z A;  1KQC A;  3BM2 A;  3GH8 A;  2BKJ A;  1YLU A;  3HOI A;  2ISJ A;  2WZV A;  3BEM A;  3H4O A;  1OO6 A;  1NOX A;  2WQF A;  4BN7 A;  4BNB A;  3G14 A;  1OOQ A;  5KO8 A;  5KRD A;  1ICR A;  3GB5 A;  3QDL A;  4XOM A;  3BM1 A;  1J6R A;  3PXV A;  3N2S A;  4TTC A;  1VFR A;  5HEI A;  1ICU A;  4QLX A;  3GFA A;  1ICV A;  2ISK A;  2WZW A;  5J6C A;  2YMV A;  1VKW A;  2R01 A;  3M5K A;  3GAG A;  4URP A;  3GR3 A;  1OO5 A;  2IFA A;  1YWQ A;  1ZCH A;  1V5Y A;  2FRE A;  3EO8 A;  1YLR A;  3X22 A;  2B67 A;  3X21 A;  3KWK A;  2ISL A;  4DN2 A;  1DS7 A;  3K6H A;  1NEC A;  3GE6 A;  3HZN A;  5HDJ A;  3KOQ A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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#similar chains, but unknotted
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