1HLOA

The crystal structure of an intact human max-dna complex: new insights into mechanisms of transcriptional control
Total Genus 30
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
30
sequence length
80
structure length
80
Chain Sequence
NDDIEVESDADKRAHHNALERKRRDHIKDSFHSLRDSVPSLQGEKASRAQILDKATEYIQYMRRKNHTHQQDIDDLKRQN
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title The crystal structure of an intact human Max-DNA complex: new insights into mechanisms of transcriptional control.
pubmed doi rcsb
molecule keywords DNA (5'-D(*CP*AP*CP*CP*AP*CP*GP*TP*GP*GP*T)-3')
molecule tags Transcription/dna
source organism Homo sapiens
total genus 30
structure length 80
sequence length 80
chains with identical sequence B
ec nomenclature
pdb deposition date 1997-09-10

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00010 HLH Helix-loop-helix DNA-binding domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
4.10.280.10 Few Secondary Structures Irregular MYOD Basic-Helix-Loop-Helix Domain, subunit B Helix-loop-helix DNA-binding domain 1hloA00
2YPBB 2QL2A 4H10A 5I50A 1AM9A 2MH3A 2QL2B 4H10B 1HLOA 4ATHA 2LFHA 5I4ZA 1A0AA 4ATKA 1NKPA 2YPAA 4ATIA 1UKLC 4F3LA 2YPAB 1MDYA 1NKPB 1R05A 5EYOA 3U5VA 4AYAA 1MDYB 4F3LB 3MUJA 1NLWA 2YPBA 1AN4A 1AN2A 1NLWB
chains in the Genus database with same CATH superfamily
2YPBB 2QL2A 4H10A 5I50A 1AM9A 2MH3A 2QL2B 4H10B 1HLOA 4ATHA 2LFHA 1K1FA 5I4ZA 1A0AA 4ATKA 1NKPA 2YPAA 4ATIA 1UKLC 4F3LA 2YPAB 1MDYA 1NKPB 1R05A 5EYOA 3U5VA 4AYAA 1MDYB 4F3LB 3MUJA 1NLWA 1ZZAA 2YPBA 1AN4A 1AN2A 1NLWB
chains in the Genus database with same CATH topology
2YPBB 2QL2A 4H10A 5I50A 1AM9A 2MH3A 2QL2B 4H10B 1HLOA 4ATHA 2LFHA 5I4ZA 1A0AA 4ATKA 1NKPA 2YPAA 4ATIA 1UKLC 4F3LA 2YPAB 1MDYA 1NKPB 1R05A 5EYOA 3U5VA 4AYAA 1MDYB 4F3LB 3MUJA 1NLWA 2YPBA 1AN4A 1AN2A 1NLWB
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2YPB B;  2QL2 A;  4H10 A;  5I50 A;  1AM9 A;  2MH3 A;  2QL2 B;  4H10 B;  1HLO A;  4ATH A;  2LFH A;  5I4Z A;  1A0A A;  4ATK A;  1NKP A;  2YPA A;  4ATI A;  1UKL C;  4F3L A;  2YPA B;  1MDY A;  1NKP B;  1R05 A;  5EYO A;  3U5V A;  4AYA A;  1MDY B;  4F3L B;  3MUJ A;  1NLW A;  2YPB A;  1AN4 A;  1AN2 A;  1NLW B; 
#chains in the Genus database with same CATH topology
 2YPB B;  2QL2 A;  4H10 A;  5I50 A;  1AM9 A;  2MH3 A;  2QL2 B;  4H10 B;  1HLO A;  4ATH A;  2LFH A;  1K1F A;  5I4Z A;  1A0A A;  4ATK A;  1NKP A;  2YPA A;  4ATI A;  1UKL C;  4F3L A;  2YPA B;  1MDY A;  1NKP B;  1R05 A;  5EYO A;  3U5V A;  4AYA A;  1MDY B;  4F3L B;  3MUJ A;  1NLW A;  1ZZA A;  2YPB A;  1AN4 A;  1AN2 A;  1NLW B; 
#chains in the Genus database with same CATH homology
 2YPB B;  2QL2 A;  4H10 A;  5I50 A;  1AM9 A;  2MH3 A;  2QL2 B;  4H10 B;  1HLO A;  4ATH A;  2LFH A;  5I4Z A;  1A0A A;  4ATK A;  1NKP A;  2YPA A;  4ATI A;  1UKL C;  4F3L A;  2YPA B;  1MDY A;  1NKP B;  1R05 A;  5EYO A;  3U5V A;  4AYA A;  1MDY B;  4F3L B;  3MUJ A;  1NLW A;  2YPB A;  1AN4 A;  1AN2 A;  1NLW B; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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#similar chains, but unknotted
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