1HLOA

The crystal structure of an intact human max-dna complex: new insights into mechanisms of transcriptional control
Total Genus 30
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
30
sequence length
80
structure length
80
Chain Sequence
NDDIEVESDADKRAHHNALERKRRDHIKDSFHSLRDSVPSLQGEKASRAQILDKATEYIQYMRRKNHTHQQDIDDLKRQN
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title The crystal structure of an intact human Max-DNA complex: new insights into mechanisms of transcriptional control.
pubmed doi rcsb
molecule tags Transcription/dna
source organism Homo sapiens
molecule keywords DNA (5'-D(*CP*AP*CP*CP*AP*CP*GP*TP*GP*GP*T)-3')
total genus 30
structure length 80
sequence length 80
chains with identical sequence B
ec nomenclature
pdb deposition date 1997-09-10

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00010 HLH Helix-loop-helix DNA-binding domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
4.10.280.10 Few Secondary Structures Irregular MYOD Basic-Helix-Loop-Helix Domain, subunit B Helix-loop-helix DNA-binding domain 1hloA00
2YPAA 2LFHA 4ATHA 2YPBB 1NKPB 4ATIA 1AN4A 1MDYB 4H10B 2YPBA 4ATKA 1NKPA 4F3LB 2MH3A 1MDYA 5EYOA 4H10A 4F3LA 1AM9A 3U5VA 1R05A 5I50A 1NLWB 1UKLC 3MUJA 2QL2B 1AN2A 1A0AA 1NLWA 2YPAB 4AYAA 2QL2A 5I4ZA 1HLOA
chains in the Genus database with same CATH superfamily
2YPAA 2LFHA 4ATHA 2YPBB 1NKPB 4ATIA 1AN4A 1MDYB 4H10B 2YPBA 4ATKA 1NKPA 4F3LB 2MH3A 1MDYA 5EYOA 4H10A 4F3LA 1AM9A 3U5VA 1R05A 5I50A 1NLWB 1UKLC 3MUJA 2QL2B 1AN2A 1A0AA 1NLWA 1ZZAA 2YPAB 4AYAA 2QL2A 5I4ZA 1K1FA 1HLOA
chains in the Genus database with same CATH topology
2YPAA 2LFHA 4ATHA 2YPBB 1NKPB 4ATIA 1AN4A 1MDYB 4H10B 2YPBA 4ATKA 1NKPA 4F3LB 2MH3A 1MDYA 5EYOA 4H10A 4F3LA 1AM9A 3U5VA 1R05A 5I50A 1NLWB 1UKLC 3MUJA 2QL2B 1AN2A 1A0AA 1NLWA 2YPAB 4AYAA 2QL2A 5I4ZA 1HLOA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2YPA A;  2LFH A;  4ATH A;  2YPB B;  1NKP B;  4ATI A;  1AN4 A;  1MDY B;  4H10 B;  2YPB A;  4ATK A;  1NKP A;  4F3L B;  2MH3 A;  1MDY A;  5EYO A;  4H10 A;  4F3L A;  1AM9 A;  3U5V A;  1R05 A;  5I50 A;  1NLW B;  1UKL C;  3MUJ A;  2QL2 B;  1AN2 A;  1A0A A;  1NLW A;  2YPA B;  4AYA A;  2QL2 A;  5I4Z A;  1HLO A; 
#chains in the Genus database with same CATH topology
 2YPA A;  2LFH A;  4ATH A;  2YPB B;  1NKP B;  4ATI A;  1AN4 A;  1MDY B;  4H10 B;  2YPB A;  4ATK A;  1NKP A;  4F3L B;  2MH3 A;  1MDY A;  5EYO A;  4H10 A;  4F3L A;  1AM9 A;  3U5V A;  1R05 A;  5I50 A;  1NLW B;  1UKL C;  3MUJ A;  2QL2 B;  1AN2 A;  1A0A A;  1NLW A;  1ZZA A;  2YPA B;  4AYA A;  2QL2 A;  5I4Z A;  1K1F A;  1HLO A; 
#chains in the Genus database with same CATH homology
 2YPA A;  2LFH A;  4ATH A;  2YPB B;  1NKP B;  4ATI A;  1AN4 A;  1MDY B;  4H10 B;  2YPB A;  4ATK A;  1NKP A;  4F3L B;  2MH3 A;  1MDY A;  5EYO A;  4H10 A;  4F3L A;  1AM9 A;  3U5V A;  1R05 A;  5I50 A;  1NLW B;  1UKL C;  3MUJ A;  2QL2 B;  1AN2 A;  1A0A A;  1NLW A;  2YPA B;  4AYA A;  2QL2 A;  5I4Z A;  1HLO A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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#similar chains, but unknotted
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