2QL2B

Crystal structure of the basic-helix-loop-helix domains of the heterodimer e47/neurod1 bound to dna
Total Genus 23
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
23
sequence length
59
structure length
59
Chain Sequence
SRRMKANARERNRMHGLNAALDNLRKVVPCYSKTQKLSKIETLRLAKNYIWALSEILRS
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Crystal structure of E47-NeuroD1/beta2 bHLH domain-DNA complex: heterodimer selectivity and DNA recognition.
pubmed doi rcsb
molecule tags Transcription/dna
source organism Mus musculus
molecule keywords Transcription factor E2-alpha
total genus 23
structure length 59
sequence length 59
chains with identical sequence D
ec nomenclature
pdb deposition date 2007-07-12

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
B PF00010 HLH Helix-loop-helix DNA-binding domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
4.10.280.10 Few Secondary Structures Irregular MYOD Basic-Helix-Loop-Helix Domain, subunit B Helix-loop-helix DNA-binding domain 2ql2B00
4ATKA 3MUJA 1NKPB 2YPBB 2MH3A 4ATHA 4AYAA 2QL2A 1MDYA 1HLOA 1UKLC 5I4ZA 2YPAB 1A0AA 4ATIA 1NLWA 2YPBA 1NKPA 1AM9A 1R05A 3U5VA 4H10B 4F3LB 1AN4A 5I50A 1MDYB 2LFHA 2QL2B 2YPAA 1AN2A 5EYOA 4H10A 1NLWB 4F3LA
chains in the Genus database with same CATH superfamily
4ATKA 3MUJA 1NKPB 2YPBB 2MH3A 4ATHA 4AYAA 2QL2A 1MDYA 1HLOA 1UKLC 1ZZAA 5I4ZA 1K1FA 2YPAB 1A0AA 4ATIA 1NLWA 2YPBA 1NKPA 1AM9A 1R05A 3U5VA 4H10B 4F3LB 1AN4A 5I50A 1MDYB 2LFHA 2QL2B 2YPAA 1AN2A 5EYOA 4H10A 1NLWB 4F3LA
chains in the Genus database with same CATH topology
4ATKA 3MUJA 1NKPB 2YPBB 2MH3A 4ATHA 4AYAA 2QL2A 1MDYA 1HLOA 1UKLC 5I4ZA 2YPAB 1A0AA 4ATIA 1NLWA 2YPBA 1NKPA 1AM9A 1R05A 3U5VA 4H10B 4F3LB 1AN4A 5I50A 1MDYB 2LFHA 2QL2B 2YPAA 1AN2A 5EYOA 4H10A 1NLWB 4F3LA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4ATK A;  3MUJ A;  1NKP B;  2YPB B;  2MH3 A;  4ATH A;  4AYA A;  2QL2 A;  1MDY A;  1HLO A;  1UKL C;  5I4Z A;  2YPA B;  1A0A A;  4ATI A;  1NLW A;  2YPB A;  1NKP A;  1AM9 A;  1R05 A;  3U5V A;  4H10 B;  4F3L B;  1AN4 A;  5I50 A;  1MDY B;  2LFH A;  2QL2 B;  2YPA A;  1AN2 A;  5EYO A;  4H10 A;  1NLW B;  4F3L A; 
#chains in the Genus database with same CATH topology
 4ATK A;  3MUJ A;  1NKP B;  2YPB B;  2MH3 A;  4ATH A;  4AYA A;  2QL2 A;  1MDY A;  1HLO A;  1UKL C;  1ZZA A;  5I4Z A;  1K1F A;  2YPA B;  1A0A A;  4ATI A;  1NLW A;  2YPB A;  1NKP A;  1AM9 A;  1R05 A;  3U5V A;  4H10 B;  4F3L B;  1AN4 A;  5I50 A;  1MDY B;  2LFH A;  2QL2 B;  2YPA A;  1AN2 A;  5EYO A;  4H10 A;  1NLW B;  4F3L A; 
#chains in the Genus database with same CATH homology
 4ATK A;  3MUJ A;  1NKP B;  2YPB B;  2MH3 A;  4ATH A;  4AYA A;  2QL2 A;  1MDY A;  1HLO A;  1UKL C;  5I4Z A;  2YPA B;  1A0A A;  4ATI A;  1NLW A;  2YPB A;  1NKP A;  1AM9 A;  1R05 A;  3U5V A;  4H10 B;  4F3L B;  1AN4 A;  5I50 A;  1MDY B;  2LFH A;  2QL2 B;  2YPA A;  1AN2 A;  5EYO A;  4H10 A;  1NLW B;  4F3L A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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