1ICRA

The structure of escherichia coli nitroreductase complexed with nicotinic acid
Total Genus 72
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
72
sequence length
216
structure length
216
Chain Sequence
DIISVALKRHSTKAFDASKKLTPEQAEQIKTLLQYSPSSTNSQPWHFIVASTEEGKARVAKSAAGNYVFNERKMLDASHVVVFCAKTAMDDVWLKLVVDQEDADGRFATPEAKAANDKGRKFFADMHRKDLHDDAEWMAKQVYLNVGNFLLGVAALGLDAVPIEGFDAAILDAEFGLKEKGYTSLVVVPVGHHSVEDFNATLPKSRLPQNITLTEV
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title The structure of Escherichia coli nitroreductase complexed with nicotinic acid: three crystal forms at 1.7 A, 1.8 A and 2.4 A resolution.
pubmed doi rcsb
molecule tags Oxidoreductase
source organism Escherichia coli
molecule keywords OXYGEN-INSENSITIVE NAD(P)H NITROREDUCTASE
total genus 72
structure length 216
sequence length 216
chains with identical sequence B
ec nomenclature ec 1.5.1.34: 6,7-dihydropteridine reductase.
pdb deposition date 2001-04-02

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00881 Nitroreductase Nitroreductase family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.109.10 Alpha Beta 3-Layer(aba) Sandwich NADH Oxidase NADH Oxidase 1icrA00
3BM1A 3N2SA 3GE6A 2FREA 3EOFA 3PXVA 1OONA 3G14A 2HAYA 4BN8A 5HEIA 2ISLA 3GAGA 1V5YA 3K6HA 4URPA 1KQCA 4BN9A 4BN6A 3GFAA 3H4OA 3BM2A 1BKJA 1ZCHA 3E39A 4XOMA 4EO3A 3TO0A 1ICVA 3E10A 1YKIA 5HDJA 3HOIA 3EK3A 3BEMA 2WZWA 4TTCA 5KRDA 3GE5A 3KWKA 1NOXA 2BKJA 2ISJA 1KQDA 5KO7A 3M5KA 1IDTA 2WQFA 4XOQA 4DN2A 4TTBA 1KQBA 3GR3A 3OF4A 3X22A 1YWQA 3HJ9A 1VFRA 3GBHA 3HZNA 3X21A 1F5VA 4BN7A 1NECA 1YLRA 1OOQA 2YMVA 3EO7A 3EO8A 1VKWA 4QLYA 2B67A 3GB5A 3QDLA 1YLUA 2H0UA 1OO6A 3TNZA 1DS7A 4BNBA 3KOQA 1ICRA 2WZVA 2IFAA 4G8SA 1ICUA 1OO5A 5J6CA 3GFDA 2I7HA 4QLXA 2ISKA 5KO8A 4XOOA 2R01A 3GH8A 1V5ZA
chains in the Genus database with same CATH superfamily
3BM1A 3N2SA 3GE6A 2FREA 3EOFA 3PXVA 1OONA 3G14A 2HAYA 4BN8A 5HEIA 2ISLA 3GAGA 1V5YA 3K6HA 4URPA 1KQCA 4BN9A 4BN6A 3GFAA 3H4OA 3BM2A 1BKJA 1ZCHA 3E39A 4XOMA 4EO3A 3TO0A 1ICVA 3E10A 1YKIA 5HDJA 3HOIA 3EK3A 3BEMA 2WZWA 4TTCA 5KRDA 3GE5A 3KWKA 1NOXA 2BKJA 2ISJA 1KQDA 5KO7A 3M5KA 1IDTA 2WQFA 4XOQA 4DN2A 4TTBA 1KQBA 3GR3A 3OF4A 3X22A 1YWQA 3HJ9A 1VFRA 3GBHA 3HZNA 3X21A 1F5VA 4BN7A 1NECA 1YLRA 1OOQA 2YMVA 3EO7A 3EO8A 1VKWA 4QLYA 2B67A 3GB5A 3QDLA 1J6RA 1YLUA 2H0UA 1OO6A 3TNZA 1DS7A 4BNBA 3KOQA 1ICRA 2WZVA 2IFAA 4G8SA 1ICUA 1OO5A 5J6CA 3GFDA 2I7HA 4QLXA 2ISKA 5KO8A 4XOOA 2R01A 3GH8A 1V5ZA
chains in the Genus database with same CATH topology
3BM1A 3N2SA 3GE6A 2FREA 3EOFA 3PXVA 1OONA 3G14A 2HAYA 4BN8A 5HEIA 2ISLA 3GAGA 1V5YA 3K6HA 4URPA 1KQCA 4BN9A 4BN6A 3GFAA 3H4OA 3BM2A 1BKJA 1ZCHA 3E39A 4XOMA 4EO3A 3TO0A 1ICVA 3E10A 1YKIA 5HDJA 3HOIA 3EK3A 3BEMA 2WZWA 4TTCA 5KRDA 3GE5A 3KWKA 1NOXA 2BKJA 2ISJA 1KQDA 5KO7A 3M5KA 1IDTA 2WQFA 4XOQA 4DN2A 4TTBA 1KQBA 3GR3A 3OF4A 3X22A 1YWQA 3HJ9A 1VFRA 3GBHA 3HZNA 3X21A 1F5VA 4BN7A 1NECA 1YLRA 1OOQA 2YMVA 3EO7A 3EO8A 1VKWA 4QLYA 2B67A 3GB5A 3QDLA 1J6RA 1YLUA 2H0UA 1OO6A 3TNZA 1DS7A 4BNBA 3KOQA 1ICRA 2WZVA 2IFAA 4G8SA 1ICUA 1OO5A 5J6CA 3GFDA 2I7HA 4QLXA 2ISKA 5KO8A 4XOOA 2R01A 3GH8A 1V5ZA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3BM1 A;  3N2S A;  3GE6 A;  2FRE A;  3EOF A;  3PXV A;  1OON A;  3G14 A;  2HAY A;  4BN8 A;  5HEI A;  2ISL A;  3GAG A;  1V5Y A;  3K6H A;  4URP A;  1KQC A;  4BN9 A;  4BN6 A;  3GFA A;  3H4O A;  3BM2 A;  1BKJ A;  1ZCH A;  3E39 A;  4XOM A;  4EO3 A;  3TO0 A;  1ICV A;  3E10 A;  1YKI A;  5HDJ A;  3HOI A;  3EK3 A;  3BEM A;  2WZW A;  4TTC A;  5KRD A;  3GE5 A;  3KWK A;  1NOX A;  2BKJ A;  2ISJ A;  1KQD A;  5KO7 A;  3M5K A;  1IDT A;  2WQF A;  4XOQ A;  4DN2 A;  4TTB A;  1KQB A;  3GR3 A;  3OF4 A;  3X22 A;  1YWQ A;  3HJ9 A;  1VFR A;  3GBH A;  3HZN A;  3X21 A;  1F5V A;  4BN7 A;  1NEC A;  1YLR A;  1OOQ A;  2YMV A;  3EO7 A;  3EO8 A;  1VKW A;  4QLY A;  2B67 A;  3GB5 A;  3QDL A;  1YLU A;  2H0U A;  1OO6 A;  3TNZ A;  1DS7 A;  4BNB A;  3KOQ A;  1ICR A;  2WZV A;  2IFA A;  4G8S A;  1ICU A;  1OO5 A;  5J6C A;  3GFD A;  2I7H A;  4QLX A;  2ISK A;  5KO8 A;  4XOO A;  2R01 A;  3GH8 A;  1V5Z A; 
#chains in the Genus database with same CATH topology
 3BM1 A;  3N2S A;  3GE6 A;  2FRE A;  3EOF A;  3PXV A;  1OON A;  3G14 A;  2HAY A;  4BN8 A;  5HEI A;  2ISL A;  3GAG A;  1V5Y A;  3K6H A;  4URP A;  1KQC A;  4BN9 A;  4BN6 A;  3GFA A;  3H4O A;  3BM2 A;  1BKJ A;  1ZCH A;  3E39 A;  4XOM A;  4EO3 A;  3TO0 A;  1ICV A;  3E10 A;  1YKI A;  5HDJ A;  3HOI A;  3EK3 A;  3BEM A;  2WZW A;  4TTC A;  5KRD A;  3GE5 A;  3KWK A;  1NOX A;  2BKJ A;  2ISJ A;  1KQD A;  5KO7 A;  3M5K A;  1IDT A;  2WQF A;  4XOQ A;  4DN2 A;  4TTB A;  1KQB A;  3GR3 A;  3OF4 A;  3X22 A;  1YWQ A;  3HJ9 A;  1VFR A;  3GBH A;  3HZN A;  3X21 A;  1F5V A;  4BN7 A;  1NEC A;  1YLR A;  1OOQ A;  2YMV A;  3EO7 A;  3EO8 A;  1VKW A;  4QLY A;  2B67 A;  3GB5 A;  3QDL A;  1J6R A;  1YLU A;  2H0U A;  1OO6 A;  3TNZ A;  1DS7 A;  4BNB A;  3KOQ A;  1ICR A;  2WZV A;  2IFA A;  4G8S A;  1ICU A;  1OO5 A;  5J6C A;  3GFD A;  2I7H A;  4QLX A;  2ISK A;  5KO8 A;  4XOO A;  2R01 A;  3GH8 A;  1V5Z A; 
#chains in the Genus database with same CATH homology
 3BM1 A;  3N2S A;  3GE6 A;  2FRE A;  3EOF A;  3PXV A;  1OON A;  3G14 A;  2HAY A;  4BN8 A;  5HEI A;  2ISL A;  3GAG A;  1V5Y A;  3K6H A;  4URP A;  1KQC A;  4BN9 A;  4BN6 A;  3GFA A;  3H4O A;  3BM2 A;  1BKJ A;  1ZCH A;  3E39 A;  4XOM A;  4EO3 A;  3TO0 A;  1ICV A;  3E10 A;  1YKI A;  5HDJ A;  3HOI A;  3EK3 A;  3BEM A;  2WZW A;  4TTC A;  5KRD A;  3GE5 A;  3KWK A;  1NOX A;  2BKJ A;  2ISJ A;  1KQD A;  5KO7 A;  3M5K A;  1IDT A;  2WQF A;  4XOQ A;  4DN2 A;  4TTB A;  1KQB A;  3GR3 A;  3OF4 A;  3X22 A;  1YWQ A;  3HJ9 A;  1VFR A;  3GBH A;  3HZN A;  3X21 A;  1F5V A;  4BN7 A;  1NEC A;  1YLR A;  1OOQ A;  2YMV A;  3EO7 A;  3EO8 A;  1VKW A;  4QLY A;  2B67 A;  3GB5 A;  3QDL A;  1J6R A;  1YLU A;  2H0U A;  1OO6 A;  3TNZ A;  1DS7 A;  4BNB A;  3KOQ A;  1ICR A;  2WZV A;  2IFA A;  4G8S A;  1ICU A;  1OO5 A;  5J6C A;  3GFD A;  2I7H A;  4QLX A;  2ISK A;  5KO8 A;  4XOO A;  2R01 A;  3GH8 A;  1V5Z A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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