1KQDA

Structure of nitroreductase from e. cloacae bound with 2e-reduced flavin mononucleotide (fmn)
Total Genus 74
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
74
sequence length
216
structure length
216
Chain Sequence
DIISVALKRHSTKAFDASKKLTAEEAEKIKTLLQYSPSSTNSQPWHFIVASTEEGKARVAKSAAGTYVFNERKMLDASHVVVFCAKTAMDDAWLERVVDQEEADGRFNTPEAKAANHKGRTYFADMHRVDLKDDDQWMAKQVYLNVGNFLLGVGAMGLDAVPIEGFDAAILDEEFGLKEKGFTSLVVVPVGHHSVEDFNATLPKSRLPLSTIVTEC
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structures of nitroreductase in three states: effects of inhibitor binding and reduction.
pubmed doi rcsb
molecule tags Oxidoreductase
source organism Enterobacter cloacae
molecule keywords OXYGEN-INSENSITIVE NAD(P)H NITROREDUCTASE
total genus 74
structure length 216
sequence length 216
chains with identical sequence B, C, D
ec nomenclature ec 1.6.6.-:
pdb deposition date 2002-01-04

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00881 Nitroreductase Nitroreductase family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.109.10 Alpha Beta 3-Layer(aba) Sandwich NADH Oxidase NADH Oxidase 1kqdA00
5J6CA 3X21A 3EO8A 1YWQA 2FREA 3GE5A 4EO3A 3KWKA 3HJ9A 1ICUA 5KO7A 4XOMA 3E10A 3GBHA 4XOOA 1OO5A 4BN7A 1OOQA 1NECA 1OO6A 2ISKA 3BM2A 1KQBA 3PXVA 1KQCA 1OONA 3H4OA 1NOXA 1DS7A 4XOQA 1V5ZA 2B67A 1V5YA 3GR3A 3K6HA 5HDJA 3TO0A 5KRDA 5KO8A 2IFAA 2WZWA 3EOFA 3GB5A 4QLYA 4QLXA 4TTCA 4BNBA 1VKWA 3BM1A 5HEIA 1F5VA 2WZVA 3N2SA 4G8SA 3E39A 4BN9A 3EO7A 3QDLA 3TNZA 3X22A 4TTBA 3M5KA 2ISLA 3G14A 2H0UA 3BEMA 4DN2A 3GH8A 3OF4A 3EK3A 2BKJA 2ISJA 1YKIA 2WQFA 1VFRA 3HZNA 4BN6A 3GFDA 4URPA 3GAGA 2HAYA 1YLUA 1ICVA 2YMVA 1BKJA 1YLRA 1KQDA 3KOQA 2I7HA 3GE6A 4BN8A 1ICRA 1IDTA 1ZCHA 2R01A 3HOIA 3GFAA
chains in the Genus database with same CATH superfamily
5J6CA 3X21A 3EO8A 1YWQA 2FREA 3GE5A 4EO3A 3KWKA 3HJ9A 1ICUA 5KO7A 4XOMA 3E10A 3GBHA 4XOOA 1OO5A 4BN7A 1OOQA 1NECA 1OO6A 2ISKA 3BM2A 1KQBA 3PXVA 1KQCA 1OONA 3H4OA 1NOXA 1DS7A 1J6RA 4XOQA 1V5ZA 2B67A 1V5YA 3GR3A 3K6HA 5HDJA 3TO0A 5KRDA 5KO8A 2IFAA 2WZWA 3EOFA 3GB5A 4QLYA 4QLXA 4TTCA 4BNBA 1VKWA 3BM1A 5HEIA 1F5VA 2WZVA 3N2SA 4G8SA 3E39A 4BN9A 3EO7A 3QDLA 3TNZA 3X22A 4TTBA 3M5KA 2ISLA 3G14A 2H0UA 3BEMA 4DN2A 3GH8A 3OF4A 3EK3A 2BKJA 2ISJA 1YKIA 2WQFA 1VFRA 3HZNA 4BN6A 3GFDA 4URPA 3GAGA 2HAYA 1YLUA 1ICVA 2YMVA 1BKJA 1YLRA 1KQDA 3KOQA 2I7HA 3GE6A 4BN8A 1ICRA 1IDTA 1ZCHA 2R01A 3HOIA 3GFAA
chains in the Genus database with same CATH topology
5J6CA 3X21A 3EO8A 1YWQA 2FREA 3GE5A 4EO3A 3KWKA 3HJ9A 1ICUA 5KO7A 4XOMA 3E10A 3GBHA 4XOOA 1OO5A 4BN7A 1OOQA 1NECA 1OO6A 2ISKA 3BM2A 1KQBA 3PXVA 1KQCA 1OONA 3H4OA 1NOXA 1DS7A 1J6RA 4XOQA 1V5ZA 2B67A 1V5YA 3GR3A 3K6HA 5HDJA 3TO0A 5KRDA 5KO8A 2IFAA 2WZWA 3EOFA 3GB5A 4QLYA 4QLXA 4TTCA 4BNBA 1VKWA 3BM1A 5HEIA 1F5VA 2WZVA 3N2SA 4G8SA 3E39A 4BN9A 3EO7A 3QDLA 3TNZA 3X22A 4TTBA 3M5KA 2ISLA 3G14A 2H0UA 3BEMA 4DN2A 3GH8A 3OF4A 3EK3A 2BKJA 2ISJA 1YKIA 2WQFA 1VFRA 3HZNA 4BN6A 3GFDA 4URPA 3GAGA 2HAYA 1YLUA 1ICVA 2YMVA 1BKJA 1YLRA 1KQDA 3KOQA 2I7HA 3GE6A 4BN8A 1ICRA 1IDTA 1ZCHA 2R01A 3HOIA 3GFAA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5J6C A;  3X21 A;  3EO8 A;  1YWQ A;  2FRE A;  3GE5 A;  4EO3 A;  3KWK A;  3HJ9 A;  1ICU A;  5KO7 A;  4XOM A;  3E10 A;  3GBH A;  4XOO A;  1OO5 A;  4BN7 A;  1OOQ A;  1NEC A;  1OO6 A;  2ISK A;  3BM2 A;  1KQB A;  3PXV A;  1KQC A;  1OON A;  3H4O A;  1NOX A;  1DS7 A;  4XOQ A;  1V5Z A;  2B67 A;  1V5Y A;  3GR3 A;  3K6H A;  5HDJ A;  3TO0 A;  5KRD A;  5KO8 A;  2IFA A;  2WZW A;  3EOF A;  3GB5 A;  4QLY A;  4QLX A;  4TTC A;  4BNB A;  1VKW A;  3BM1 A;  5HEI A;  1F5V A;  2WZV A;  3N2S A;  4G8S A;  3E39 A;  4BN9 A;  3EO7 A;  3QDL A;  3TNZ A;  3X22 A;  4TTB A;  3M5K A;  2ISL A;  3G14 A;  2H0U A;  3BEM A;  4DN2 A;  3GH8 A;  3OF4 A;  3EK3 A;  2BKJ A;  2ISJ A;  1YKI A;  2WQF A;  1VFR A;  3HZN A;  4BN6 A;  3GFD A;  4URP A;  3GAG A;  2HAY A;  1YLU A;  1ICV A;  2YMV A;  1BKJ A;  1YLR A;  1KQD A;  3KOQ A;  2I7H A;  3GE6 A;  4BN8 A;  1ICR A;  1IDT A;  1ZCH A;  2R01 A;  3HOI A;  3GFA A; 
#chains in the Genus database with same CATH topology
 5J6C A;  3X21 A;  3EO8 A;  1YWQ A;  2FRE A;  3GE5 A;  4EO3 A;  3KWK A;  3HJ9 A;  1ICU A;  5KO7 A;  4XOM A;  3E10 A;  3GBH A;  4XOO A;  1OO5 A;  4BN7 A;  1OOQ A;  1NEC A;  1OO6 A;  2ISK A;  3BM2 A;  1KQB A;  3PXV A;  1KQC A;  1OON A;  3H4O A;  1NOX A;  1DS7 A;  1J6R A;  4XOQ A;  1V5Z A;  2B67 A;  1V5Y A;  3GR3 A;  3K6H A;  5HDJ A;  3TO0 A;  5KRD A;  5KO8 A;  2IFA A;  2WZW A;  3EOF A;  3GB5 A;  4QLY A;  4QLX A;  4TTC A;  4BNB A;  1VKW A;  3BM1 A;  5HEI A;  1F5V A;  2WZV A;  3N2S A;  4G8S A;  3E39 A;  4BN9 A;  3EO7 A;  3QDL A;  3TNZ A;  3X22 A;  4TTB A;  3M5K A;  2ISL A;  3G14 A;  2H0U A;  3BEM A;  4DN2 A;  3GH8 A;  3OF4 A;  3EK3 A;  2BKJ A;  2ISJ A;  1YKI A;  2WQF A;  1VFR A;  3HZN A;  4BN6 A;  3GFD A;  4URP A;  3GAG A;  2HAY A;  1YLU A;  1ICV A;  2YMV A;  1BKJ A;  1YLR A;  1KQD A;  3KOQ A;  2I7H A;  3GE6 A;  4BN8 A;  1ICR A;  1IDT A;  1ZCH A;  2R01 A;  3HOI A;  3GFA A; 
#chains in the Genus database with same CATH homology
 5J6C A;  3X21 A;  3EO8 A;  1YWQ A;  2FRE A;  3GE5 A;  4EO3 A;  3KWK A;  3HJ9 A;  1ICU A;  5KO7 A;  4XOM A;  3E10 A;  3GBH A;  4XOO A;  1OO5 A;  4BN7 A;  1OOQ A;  1NEC A;  1OO6 A;  2ISK A;  3BM2 A;  1KQB A;  3PXV A;  1KQC A;  1OON A;  3H4O A;  1NOX A;  1DS7 A;  1J6R A;  4XOQ A;  1V5Z A;  2B67 A;  1V5Y A;  3GR3 A;  3K6H A;  5HDJ A;  3TO0 A;  5KRD A;  5KO8 A;  2IFA A;  2WZW A;  3EOF A;  3GB5 A;  4QLY A;  4QLX A;  4TTC A;  4BNB A;  1VKW A;  3BM1 A;  5HEI A;  1F5V A;  2WZV A;  3N2S A;  4G8S A;  3E39 A;  4BN9 A;  3EO7 A;  3QDL A;  3TNZ A;  3X22 A;  4TTB A;  3M5K A;  2ISL A;  3G14 A;  2H0U A;  3BEM A;  4DN2 A;  3GH8 A;  3OF4 A;  3EK3 A;  2BKJ A;  2ISJ A;  1YKI A;  2WQF A;  1VFR A;  3HZN A;  4BN6 A;  3GFD A;  4URP A;  3GAG A;  2HAY A;  1YLU A;  1ICV A;  2YMV A;  1BKJ A;  1YLR A;  1KQD A;  3KOQ A;  2I7H A;  3GE6 A;  4BN8 A;  1ICR A;  1IDT A;  1ZCH A;  2R01 A;  3HOI A;  3GFA A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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#similar chains, but unknotted
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