1MDYA

Crystal structure of myod bhlh domain bound to dna: perspectives on dna recognition and implications for transcriptional activation
Total Genus 22
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
22
sequence length
68
structure length
68
Chain Sequence
MELKRKTTNADRRKAATMRERRRLSKVNEAFETLKRSTSSNPNQRLPKVEILRNAIRYIEGLQALLRD
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Crystal structure of MyoD bHLH domain-DNA complex: perspectives on DNA recognition and implications for transcriptional activation.
pubmed doi rcsb
molecule tags Transcription/dna
molecule keywords DNA (5'-D(*TP*CP*AP*AP*CP*AP*GP*CP*TP*GP*TP*TP*GP*A)-3')
total genus 22
structure length 68
sequence length 68
ec nomenclature
pdb deposition date 1994-06-09

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00010 HLH Helix-loop-helix DNA-binding domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
4.10.280.10 Few Secondary Structures Irregular MYOD Basic-Helix-Loop-Helix Domain, subunit B Helix-loop-helix DNA-binding domain 1mdyA00
4ATHA 4F3LB 4ATIA 5I50A 1MDYA 2MH3A 1AN4A 2YPBA 4ATKA 2YPAA 4F3LA 2LFHA 1AM9A 2QL2B 1HLOA 3MUJA 1NKPB 5EYOA 1AN2A 4H10B 1UKLC 1NKPA 5I4ZA 2QL2A 1NLWB 4H10A 1R05A 3U5VA 2YPBB 1MDYB 1A0AA 1NLWA 4AYAA 2YPAB
chains in the Genus database with same CATH superfamily
4ATHA 4F3LB 4ATIA 5I50A 1MDYA 2MH3A 1AN4A 2YPBA 4ATKA 2YPAA 1K1FA 4F3LA 2LFHA 1AM9A 2QL2B 1HLOA 3MUJA 1NKPB 5EYOA 1ZZAA 1AN2A 4H10B 1UKLC 1NKPA 5I4ZA 2QL2A 1NLWB 4H10A 1R05A 3U5VA 2YPBB 1MDYB 1A0AA 1NLWA 4AYAA 2YPAB
chains in the Genus database with same CATH topology
4ATHA 4F3LB 4ATIA 5I50A 1MDYA 2MH3A 1AN4A 2YPBA 4ATKA 2YPAA 4F3LA 2LFHA 1AM9A 2QL2B 1HLOA 3MUJA 1NKPB 5EYOA 1AN2A 4H10B 1UKLC 1NKPA 5I4ZA 2QL2A 1NLWB 4H10A 1R05A 3U5VA 2YPBB 1MDYB 1A0AA 1NLWA 4AYAA 2YPAB
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4ATH A;  4F3L B;  4ATI A;  5I50 A;  1MDY A;  2MH3 A;  1AN4 A;  2YPB A;  4ATK A;  2YPA A;  4F3L A;  2LFH A;  1AM9 A;  2QL2 B;  1HLO A;  3MUJ A;  1NKP B;  5EYO A;  1AN2 A;  4H10 B;  1UKL C;  1NKP A;  5I4Z A;  2QL2 A;  1NLW B;  4H10 A;  1R05 A;  3U5V A;  2YPB B;  1MDY B;  1A0A A;  1NLW A;  4AYA A;  2YPA B; 
#chains in the Genus database with same CATH topology
 4ATH A;  4F3L B;  4ATI A;  5I50 A;  1MDY A;  2MH3 A;  1AN4 A;  2YPB A;  4ATK A;  2YPA A;  1K1F A;  4F3L A;  2LFH A;  1AM9 A;  2QL2 B;  1HLO A;  3MUJ A;  1NKP B;  5EYO A;  1ZZA A;  1AN2 A;  4H10 B;  1UKL C;  1NKP A;  5I4Z A;  2QL2 A;  1NLW B;  4H10 A;  1R05 A;  3U5V A;  2YPB B;  1MDY B;  1A0A A;  1NLW A;  4AYA A;  2YPA B; 
#chains in the Genus database with same CATH homology
 4ATH A;  4F3L B;  4ATI A;  5I50 A;  1MDY A;  2MH3 A;  1AN4 A;  2YPB A;  4ATK A;  2YPA A;  4F3L A;  2LFH A;  1AM9 A;  2QL2 B;  1HLO A;  3MUJ A;  1NKP B;  5EYO A;  1AN2 A;  4H10 B;  1UKL C;  1NKP A;  5I4Z A;  2QL2 A;  1NLW B;  4H10 A;  1R05 A;  3U5V A;  2YPB B;  1MDY B;  1A0A A;  1NLW A;  4AYA A;  2YPA B; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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