1MDYB

Crystal structure of myod bhlh domain bound to dna: perspectives on dna recognition and implications for transcriptional activation
Total Genus 22
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
22
sequence length
62
structure length
62
Chain Sequence
TTNADRRKAATMRERRRLSKVNEAFETLKRSTSSNPNQRLPKVEILRNAIRYIEGLQALLRD
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Crystal structure of MyoD bHLH domain-DNA complex: perspectives on DNA recognition and implications for transcriptional activation.
pubmed doi rcsb
molecule keywords DNA (5'-D(*TP*CP*AP*AP*CP*AP*GP*CP*TP*GP*TP*TP*GP*A)-3')
molecule tags Transcription/dna
total genus 22
structure length 62
sequence length 62
chains with identical sequence C, D
ec nomenclature
pdb deposition date 1994-06-09

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
B PF00010 HLH Helix-loop-helix DNA-binding domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
4.10.280.10 Few Secondary Structures Irregular MYOD Basic-Helix-Loop-Helix Domain, subunit B Helix-loop-helix DNA-binding domain 1mdyB00
2MH3A 1NKPB 1A0AA 1NLWB 4H10A 5I50A 1R05A 4ATIA 3U5VA 2QL2A 1HLOA 2LFHA 1AM9A 4H10B 2QL2B 5EYOA 2YPBA 4ATHA 5I4ZA 2YPBB 4F3LA 1AN4A 4AYAA 1AN2A 2YPAA 1MDYA 4ATKA 1UKLC 4F3LB 3MUJA 1NKPA 1NLWA 2YPAB 1MDYB
chains in the Genus database with same CATH superfamily
2MH3A 1NKPB 1A0AA 1NLWB 4H10A 5I50A 1R05A 4ATIA 3U5VA 2QL2A 1HLOA 2LFHA 1AM9A 4H10B 2QL2B 5EYOA 2YPBA 1ZZAA 4ATHA 5I4ZA 2YPBB 4F3LA 1AN4A 4AYAA 1AN2A 1K1FA 2YPAA 1MDYA 4ATKA 1UKLC 4F3LB 3MUJA 1NKPA 1NLWA 2YPAB 1MDYB
chains in the Genus database with same CATH topology
2MH3A 1NKPB 1A0AA 1NLWB 4H10A 5I50A 1R05A 4ATIA 3U5VA 2QL2A 1HLOA 2LFHA 1AM9A 4H10B 2QL2B 5EYOA 2YPBA 4ATHA 5I4ZA 2YPBB 4F3LA 1AN4A 4AYAA 1AN2A 2YPAA 1MDYA 4ATKA 1UKLC 4F3LB 3MUJA 1NKPA 1NLWA 2YPAB 1MDYB
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2MH3 A;  1NKP B;  1A0A A;  1NLW B;  4H10 A;  5I50 A;  1R05 A;  4ATI A;  3U5V A;  2QL2 A;  1HLO A;  2LFH A;  1AM9 A;  4H10 B;  2QL2 B;  5EYO A;  2YPB A;  4ATH A;  5I4Z A;  2YPB B;  4F3L A;  1AN4 A;  4AYA A;  1AN2 A;  2YPA A;  1MDY A;  4ATK A;  1UKL C;  4F3L B;  3MUJ A;  1NKP A;  1NLW A;  2YPA B;  1MDY B; 
#chains in the Genus database with same CATH topology
 2MH3 A;  1NKP B;  1A0A A;  1NLW B;  4H10 A;  5I50 A;  1R05 A;  4ATI A;  3U5V A;  2QL2 A;  1HLO A;  2LFH A;  1AM9 A;  4H10 B;  2QL2 B;  5EYO A;  2YPB A;  1ZZA A;  4ATH A;  5I4Z A;  2YPB B;  4F3L A;  1AN4 A;  4AYA A;  1AN2 A;  1K1F A;  2YPA A;  1MDY A;  4ATK A;  1UKL C;  4F3L B;  3MUJ A;  1NKP A;  1NLW A;  2YPA B;  1MDY B; 
#chains in the Genus database with same CATH homology
 2MH3 A;  1NKP B;  1A0A A;  1NLW B;  4H10 A;  5I50 A;  1R05 A;  4ATI A;  3U5V A;  2QL2 A;  1HLO A;  2LFH A;  1AM9 A;  4H10 B;  2QL2 B;  5EYO A;  2YPB A;  4ATH A;  5I4Z A;  2YPB B;  4F3L A;  1AN4 A;  4AYA A;  1AN2 A;  2YPA A;  1MDY A;  4ATK A;  1UKL C;  4F3L B;  3MUJ A;  1NKP A;  1NLW A;  2YPA B;  1MDY B; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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