1UE0A

Isoleucyl-trna synthetase editing domain complexed with l-valine
Total Genus 50
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
50
sequence length
181
structure length
181
Chain Sequence
QDPSVYVRFPLKEPKKLGLEKASLLIWTTTPWTLPGNVAAAVHPEYTYAAFQVGDEALILEEGLGRKLLGEGTQVLKTFPGKALEGLPYTPPYPQALEKGYFVVLADYVSQEDGTGIVHQAPAFGAEDLETARVYGLPLLKTVDEEGKLLVEPFKGLYFREANRAILRDLRGRGFLFKEES
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Crystal structures of the CP1 domain from Thermus thermophilus isoleucyl-tRNA synthetase and its complex with L-valine.
pubmed doi rcsb
molecule tags Ligase
source organism Thermus thermophilus
molecule keywords Isoleucyl-tRNA synthetase
total genus 50
structure length 181
sequence length 181
chains with identical sequence B
ec nomenclature ec 6.1.1.5: Isoleucine--tRNA ligase.
pdb deposition date 2003-05-08
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.740.10 Alpha Beta Alpha-Beta Complex Isoleucyl-tRNA Synthetase; domain 2 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain 1ue0A00
2WFEA 1JZQA 5AGHA 2BTEA 1WNZA 1QU3A 1WKAA 5AGIA 3ZGZA 1ILEA 3PZ0A 2AJGA 2WFGA 4ARIA 1WK8A 2BYTA 2V0GA 4K47A 2AJIA 3ZJTA 1GAXA 1UE0A 1WNYA 1JZSA 2AJHA 3ZJVA 1WKBA 3PZ6A 1OBCA 1QU2A 3O0AA 1WZ2A 1H3NA 4CQNA 1FFYA 2V0CA 2WFDA 1UDZA 5AGRA 3PZ5A 4AS1A 5AGSA 4ARCA 3ZJUA 5AGTA 1IVSA 1WK9A 5AGJA 4AQ7A 1OBHA 4K48A
chains in the Genus database with same CATH superfamily
2WFEA 1JZQA 5AGHA 2BTEA 1WNZA 1QU3A 1WKAA 5AGIA 3ZGZA 1ILEA 3PZ0A 2AJGA 2WFGA 4ARIA 1WK8A 2BYTA 2V0GA 4K47A 2AJIA 3ZJTA 1GAXA 1UE0A 1WNYA 1JZSA 2AJHA 3ZJVA 1WKBA 3PZ6A 1OBCA 1QU2A 3O0AA 1WZ2A 1H3NA 4CQNA 1FFYA 2V0CA 2WFDA 1UDZA 5AGRA 3PZ5A 4AS1A 5AGSA 4ARCA 3ZJUA 5AGTA 1IVSA 1WK9A 5AGJA 4AQ7A 1OBHA 4K48A
chains in the Genus database with same CATH topology
2WFEA 1JZQA 5AGHA 2BTEA 1WNZA 1QU3A 1WKAA 5AGIA 3ZGZA 1ILEA 3PZ0A 2AJGA 2WFGA 4ARIA 1WK8A 2BYTA 2V0GA 4K47A 2AJIA 3ZJTA 1GAXA 1UE0A 1WNYA 1JZSA 2AJHA 3ZJVA 1WKBA 3PZ6A 1OBCA 1QU2A 3O0AA 1WZ2A 1H3NA 4CQNA 1FFYA 2V0CA 2WFDA 1UDZA 5AGRA 3PZ5A 4AS1A 5AGSA 4ARCA 3ZJUA 5AGTA 1IVSA 1WK9A 5AGJA 4AQ7A 1OBHA 4K48A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2WFE A;  1JZQ A;  5AGH A;  2BTE A;  1WNZ A;  1QU3 A;  1WKA A;  5AGI A;  3ZGZ A;  1ILE A;  3PZ0 A;  2AJG A;  2WFG A;  4ARI A;  1WK8 A;  2BYT A;  2V0G A;  4K47 A;  2AJI A;  3ZJT A;  1GAX A;  1UE0 A;  1WNY A;  1JZS A;  2AJH A;  3ZJV A;  1WKB A;  3PZ6 A;  1OBC A;  1QU2 A;  3O0A A;  1WZ2 A;  1H3N A;  4CQN A;  1FFY A;  2V0C A;  2WFD A;  1UDZ A;  5AGR A;  3PZ5 A;  4AS1 A;  5AGS A;  4ARC A;  3ZJU A;  5AGT A;  1IVS A;  1WK9 A;  5AGJ A;  4AQ7 A;  1OBH A;  4K48 A; 
#chains in the Genus database with same CATH topology
 2WFE A;  1JZQ A;  5AGH A;  2BTE A;  1WNZ A;  1QU3 A;  1WKA A;  5AGI A;  3ZGZ A;  1ILE A;  3PZ0 A;  2AJG A;  2WFG A;  4ARI A;  1WK8 A;  2BYT A;  2V0G A;  4K47 A;  2AJI A;  3ZJT A;  1GAX A;  1UE0 A;  1WNY A;  1JZS A;  2AJH A;  3ZJV A;  1WKB A;  3PZ6 A;  1OBC A;  1QU2 A;  3O0A A;  1WZ2 A;  1H3N A;  4CQN A;  1FFY A;  2V0C A;  2WFD A;  1UDZ A;  5AGR A;  3PZ5 A;  4AS1 A;  5AGS A;  4ARC A;  3ZJU A;  5AGT A;  1IVS A;  1WK9 A;  5AGJ A;  4AQ7 A;  1OBH A;  4K48 A; 
#chains in the Genus database with same CATH homology
 2WFE A;  1JZQ A;  5AGH A;  2BTE A;  1WNZ A;  1QU3 A;  1WKA A;  5AGI A;  3ZGZ A;  1ILE A;  3PZ0 A;  2AJG A;  2WFG A;  4ARI A;  1WK8 A;  2BYT A;  2V0G A;  4K47 A;  2AJI A;  3ZJT A;  1GAX A;  1UE0 A;  1WNY A;  1JZS A;  2AJH A;  3ZJV A;  1WKB A;  3PZ6 A;  1OBC A;  1QU2 A;  3O0A A;  1WZ2 A;  1H3N A;  4CQN A;  1FFY A;  2V0C A;  2WFD A;  1UDZ A;  5AGR A;  3PZ5 A;  4AS1 A;  5AGS A;  4ARC A;  3ZJU A;  5AGT A;  1IVS A;  1WK9 A;  5AGJ A;  4AQ7 A;  1OBH A;  4K48 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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